Mechanisms generating cancer genome complexity from a single cell division error von Umbreit, Neil T, Zhang, Cheng-Zhong, Lynch, Luke D, Blaine, Logan J, Cheng, Anna M, Tourdot, Richard, Sun, Lili, Almubarak, Hannah F, Judge, Kim, Mitchell, Thomas J, Spektor, Alexander, Pellman, David

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The mutational landscape of normal human endometrial epithelium von Moore, Luiza, Leongamornlert, Daniel, Coorens, Tim H. H., Sanders, Mathijs A., Ellis, Peter, Dentro, Stefan C., Dawson, Kevin J., Butler, Tim, Rahbari, Raheleh, Mitchell, Thomas J., Maura, Francesco, Nangalia, Jyoti, Tarpey, Patrick S., Brunner, Simon F., Lee-Six, Henry, Hooks, Yvette, Moody, Sarah, Mahbubani, Krishnaa T., Jimenez-Linan, Mercedes, Brosens, Jan J., Iacobuzio-Donahue, Christine A., Martincorena, Inigo, Saeb-Parsy, Kourosh, Campbell, Peter J., Stratton, Michael R.

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Genomic landscape and chronological reconstruction of driver events in multiple myeloma von Maura, Francesco, Bolli, Niccoló, Angelopoulos, Nicos, Dawson, Kevin J., Leongamornlert, Daniel, Martincorena, Inigo, Mitchell, Thomas J., Fullam, Anthony, Gonzalez, Santiago, Szalat, Raphael, Abascal, Federico, Rodriguez-Martin, Bernardo, Samur, Mehmet Kemal, Glodzik, Dominik, Roncador, Marco, Fulciniti, Mariateresa, Tai, Yu Tzu, Minvielle, Stephane, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth C., Tubio, Jose M. C., Wedge, David C., Gerstung, Moritz, Avet-Loiseau, Hervé, Munshi, Nikhil, Campbell, Peter J.

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Timing the initiation of multiple myeloma von Rustad, Even H., Yellapantula, Venkata, Leongamornlert, Daniel, Bolli, Niccolò, Ledergor, Guy, Nadeu, Ferran, Angelopoulos, Nicos, Dawson, Kevin J., Mitchell, Thomas J., Osborne, Robert J., Ziccheddu, Bachisio, Carniti, Cristiana, Montefusco, Vittorio, Corradini, Paolo, Anderson, Kenneth C., Moreau, Philippe, Papaemmanuil, Elli, Alexandrov, Ludmil B., Puente, Xose S., Campo, Elias, Siebert, Reiner, Avet-Loiseau, Herve, Landgren, Ola, Munshi, Nikhil, Campbell, Peter J., Maura, Francesco

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Interactive molecular dynamics in virtual reality from quantum chemistry to drug binding: An open-source multi-person framework von O’Connor, Michael B., Bennie, Simon J., Deeks, Helen M., Jamieson-Binnie, Alexander, Jones, Alex J., Shannon, Robin J., Walters, Rebecca, Mitchell, Thomas J., Mulholland, Adrian J., Glowacki, David R.

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Targetable NOTCH1 rearrangements in reninoma von Treger, Taryn D., Lawrence, John E. G., Anderson, Nathaniel D., Coorens, Tim H. H., Letunovska, Aleksandra, Abby, Emilie, Lee-Six, Henry, Oliver, Thomas R. W., Al-Saadi, Reem, Tullus, Kjell, Morcrette, Guillaume, Hutchinson, J. Ciaran, Rampling, Dyanne, Sebire, Neil, Pritchard-Jones, Kathy, Young, Matthew D., Mitchell, Thomas J., Jones, Philip H., Tran, Maxine, Behjati, Sam, Chowdhury, Tanzina

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Clonal diversification and histogenesis of malignant germ cell tumours von Oliver, Thomas R. W., Chappell, Lia, Sanghvi, Rashesh, Deighton, Lauren, Ansari-Pour, Naser, Dentro, Stefan C., Young, Matthew D., Coorens, Tim H. H., Jung, Hyunchul, Butler, Tim, Neville, Matthew D. C., Leongamornlert, Daniel, Sanders, Mathijs A., Hooks, Yvette, Cagan, Alex, Mitchell, Thomas J., Cortes-Ciriano, Isidro, Warren, Anne Y., Wedge, David C., Heer, Rakesh, Coleman, Nicholas, Murray, Matthew J., Campbell, Peter J., Rahbari, Raheleh, Behjati, Sam

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Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors von Smith, Christopher G, Moser, Tina, Mouliere, Florent, Field-Rayner, Johanna, Eldridge, Matthew, Riediger, Anja L, Chandrananda, Dineika, Heider, Katrin, Wan, Jonathan C M, Warren, Anne Y, Morris, James, Hudecova, Irena, Cooper, Wendy N, Mitchell, Thomas J, Gale, Davina, Ruiz-Valdepenas, Andrea, Klatte, Tobias, Ursprung, Stephan, Sala, Evis, Riddick, Antony C P, Aho, Tevita F, Armitage, James N, Perakis, Samantha, Pichler, Martin, Seles, Maximilian, Wcislo, Gabriel, Welsh, Sarah J, Matakidou, Athena, Eisen, Tim, Massie, Charles E, Rosenfeld, Nitzan, Heitzer, Ellen, Stewart, Grant D

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Src Family Kinase Activity Is Up-Regulated in Hormone-Refractory Prostate Cancer von TATAROV, Oleg, MITCHELL, Thomas J, SEYWRIGHT, Morag, LEUNG, Hing Y, BRUNTON, Valerie G, EDWARDS, Joanne

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The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel tr... von Ursprung, Stephan, Mossop, Helen, Gallagher, Ferdia A, Sala, Evis, Skells, Richard, Sipple, Jamal A N, Mitchell, Thomas J, Chhabra, Anita, Fife, Kate, Matakidou, Athena, Young, Gemma, Walker, Amanda, Thomas, Martin G, Ortuzar, Mireia Crispin, Sullivan, Mark, Protheroe, Andrew, Oades, Grenville, Venugopal, Balaji, Warren, Anne Y, Stone, John, Eisen, Tim, Wason, James, Welsh, Sarah J, Stewart, Grant D

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The mutational landscape of human somatic and germline cells von Moore, Luiza, Cagan, Alex, Coorens, Tim H. H., Neville, Matthew D. C., Sanghvi, Rashesh, Sanders, Mathijs A., Oliver, Thomas R. W., Leongamornlert, Daniel, Ellis, Peter, Noorani, Ayesha, Mitchell, Thomas J., Butler, Timothy M., Hooks, Yvette, Warren, Anne Y., Jorgensen, Mette, Dawson, Kevin J., Menzies, Andrew, O’Neill, Laura, Latimer, Calli, Teng, Mabel, van Boxtel, Ruben, Iacobuzio-Donahue, Christine A., Martincorena, Inigo, Heer, Rakesh, Campbell, Peter J., Fitzgerald, Rebecca C., Stratton, Michael R., Rahbari, Raheleh

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Multiarm, non-randomised, single-centre feasibility study—investigation of the differential biology between benign and malignant renal masses using advanced magnetic resonance imag... von Horvat-Menih, Ines, McLean, Mary A, Zamora-Morales, Maria Jesus, Wylot, Marta, Kaggie, Joshua, Khan, Alixander S, Gill, Andrew B, Duarte, Joao, Locke, Matthew J, Mendichovszky, Iosif, Li, Hao, Priest, Andrew N, Warren, Anne Y, Welsh, Sarah J, Jones, James O, Armitage, James N, Mitchell, Thomas J, Stewart, Grant D, Gallagher, Ferdia A

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Extensive phylogenies of human development inferred from somatic mutations von Coorens, Tim H. H., Moore, Luiza, Robinson, Philip S., Sanghvi, Rashesh, Christopher, Joseph, Hewinson, James, Przybilla, Moritz J., Lawson, Andrew R. J., Spencer Chapman, Michael, Cagan, Alex, Oliver, Thomas R. W., Neville, Matthew D. C., Hooks, Yvette, Noorani, Ayesha, Mitchell, Thomas J., Fitzgerald, Rebecca C., Campbell, Peter J., Martincorena, Iñigo, Rahbari, Raheleh, Stratton, Michael R.

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Establishing the reliability of rhesus macaque social network assessment from video observations von Feczko, Eric, Mitchell, Thomas A.J., Walum, Hasse, Brooks, Jenna M., Heitz, Thomas R., Young, Larry J., Parr, Lisa A.

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Extensive heterogeneity in somatic mutation and selection in the human bladder von Lawson, Andrew R J, Abascal, Federico, Coorens, Tim H H, Hooks, Yvette, O'Neill, Laura, Latimer, Calli, Raine, Keiran, Sanders, Mathijs A, Warren, Anne Y, Mahbubani, Krishnaa T A, Bareham, Bethany, Butler, Timothy M, Harvey, Luke M R, Cagan, Alex, Menzies, Andrew, Moore, Luiza, Colquhoun, Alexandra J, Turner, William, Thomas, Benjamin, Gnanapragasam, Vincent, Williams, Nicholas, Rassl, Doris M, Vöhringer, Harald, Zumalave, Sonia, Nangalia, Jyoti, Tubío, José M C, Gerstung, Moritz, Saeb-Parsy, Kourosh, Stratton, Michael R, Campbell, Peter J, Mitchell, Thomas J, Martincorena, Iñigo

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Intra-tumour diversification in colorectal cancer at the single-cell level von Roerink, Sophie F., Sasaki, Nobuo, Lee-Six, Henry, Young, Matthew D., Alexandrov, Ludmil B., Behjati, Sam, Mitchell, Thomas J., Grossmann, Sebastian, Lightfoot, Howard, Egan, David A., Pronk, Apollo, Smakman, Niels, van Gorp, Joost, Anderson, Elizabeth, Gamble, Stephen J., Alder, Chris, van de Wetering, Marc, Campbell, Peter J., Stratton, Michael R., Clevers, Hans

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Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer von Li, Ruoyan, Ferdinand, John R., Loudon, Kevin W., Bowyer, Georgina S., Laidlaw, Sean, Muyas, Francesc, Mamanova, Lira, Neves, Joana B., Bolt, Liam, Fasouli, Eirini S., Lawson, Andrew R.J., Young, Matthew D., Hooks, Yvette, Oliver, Thomas R.W., Butler, Timothy M., Armitage, James N., Aho, Tev, Riddick, Antony C.P., Gnanapragasam, Vincent, Welsh, Sarah J., Meyer, Kerstin B., Warren, Anne Y., Tran, Maxine G.B., Stewart, Grant D., Cortés-Ciriano, Isidro, Behjati, Sam, Clatworthy, Menna R., Campbell, Peter J., Teichmann, Sarah A., Mitchell, Thomas J.

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Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal von Turajlic, Samra, Xu, Hang, Litchfield, Kevin, Rowan, Andrew, Horswell, Stuart, Chambers, Tim, O’Brien, Tim, Lopez, Jose I., Watkins, Thomas B.K., Nicol, David, Stares, Mark, Challacombe, Ben, Hazell, Steve, Chandra, Ashish, Mitchell, Thomas J., Au, Lewis, Eichler-Jonsson, Claudia, Jabbar, Faiz, Soultati, Aspasia, Chowdhury, Simon, Rudman, Sarah, Lynch, Joanna, Fernando, Archana, Stamp, Gordon, Nye, Emma, Stewart, Aengus, Xing, Wei, Smith, Jonathan C., Escudero, Mickael, Huffman, Adam, Matthews, Nik, Elgar, Greg, Phillimore, Ben, Costa, Marta, Begum, Sharmin, Ward, Sophia, Salm, Max, Boeing, Stefan, Fisher, Rosalie, Spain, Lavinia, Navas, Carolina, Grönroos, Eva, Hobor, Sebastijan, Sharma, Sarkhara, Aurangzeb, Ismaeel, Lall, Sharanpreet, Polson, Alexander, Varia, Mary, Horsfield, Catherine, Fotiadis, Nicos, Pickering, Lisa, Schwarz, Roland F., Silva, Bruno, Herrero, Javier, Luscombe, Nick M., Jamal-Hanjani, Mariam, Rosenthal, Rachel, Birkbak, Nicolai J., Wilson, Gareth A., Pipek, Orsolya, Ribli, Dezso, Krzystanek, Marcin, Csabai, Istvan, Szallasi, Zoltan, Gore, Martin, McGranahan, Nicholas, Van Loo, Peter, Campbell, Peter, Larkin, James, Swanton, Charles

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Embryonal precursors of Wilms tumor von Coorens, Tim H H, Treger, Taryn D, Al-Saadi, Reem, Moore, Luiza, Tran, Maxine G B, Mitchell, Thomas J, Tugnait, Suzanne, Thevanesan, Christine, Young, Matthew D, Oliver, Thomas R W, Oostveen, Minou, Collord, Grace, Tarpey, Patrick S, Cagan, Alex, Hooks, Yvette, Brougham, Mark, Reynolds, Ben C, Barone, Giuseppe, Anderson, John, Jorgensen, Mette, Burke, G A Amos, Visser, Johannes, Nicholson, James C, Smeulders, Naima, Mushtaq, Imran, Stewart, Grant D, Campbell, Peter J, Wedge, David C, Martincorena, Iñigo, Rampling, Dyanne, Hook, Liz, Warren, Anne Y, Coleman, Nicholas, Chowdhury, Tanzina, Sebire, Neil, Drost, Jarno, Saeb-Parsy, Kourosh, Stratton, Michael R, Straathof, Karin, Pritchard-Jones, Kathy, Behjati, Sam

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Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors von Young, Matthew D, Mitchell, Thomas J, Vieira Braga, Felipe A, Tran, Maxine G B, Stewart, Benjamin J, Ferdinand, John R, Collord, Grace, Botting, Rachel A, Popescu, Dorin-Mirel, Loudon, Kevin W, Vento-Tormo, Roser, Stephenson, Emily, Cagan, Alex, Farndon, Sarah J, Del Castillo Velasco-Herrera, Martin, Guzzo, Charlotte, Richoz, Nathan, Mamanova, Lira, Aho, Tevita, Armitage, James N, Riddick, Antony C P, Mushtaq, Imran, Farrell, Stephen, Rampling, Dyanne, Nicholson, James, Filby, Andrew, Burge, Johanna, Lisgo, Steven, Maxwell, Patrick H, Lindsay, Susan, Warren, Anne Y, Stewart, Grant D, Sebire, Neil, Coleman, Nicholas, Haniffa, Muzlifah, Teichmann, Sarah A, Clatworthy, Menna, Behjati, Sam

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