canSAR chemistry registration and standardization pipeline von Dolciami, Daniela, Villasclaras-Fernandez, Eloy, Kannas, Christos, Meniconi, Mirco, Al-Lazikani, Bissan, Antolin, Albert A.

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Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase von Pollock, Katie, Liu, Manjuan, Zaleska, Mariola, Meniconi, Mirco, Pfuhl, Mark, Collins, Ian, Guettler, Sebastian

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Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhib... von Maillard, Michel C, Brookfield, Frederick A, Courtney, Stephen M, Eustache, Florence M, Gemkow, Mark J, Handel, Rebecca K, Johnson, Laura C, Johnson, Peter D, Kerry, Mark A, Krieger, Florian, Meniconi, Mirco, Muñoz-Sanjuán, Ignacio, Palfrey, Jordan J, Park, Hyunsun, Schaertl, Sabine, Taylor, Malcolm G, Weddell, Derek, Dominguez, Celia

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Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors von Davis, Owen A., Cheung, Kwai-Ming J., Brennan, Alfie, Lloyd, Matthew G., Rodrigues, Matthew J., Pierrat, Olivier A., Collie, Gavin W., Le Bihan, Yann-Vaï, Huckvale, Rosemary, Harnden, Alice C., Varela, Ana, Bright, Michael D., Eve, Paul, Hayes, Angela, Henley, Alan T., Carter, Michael D., McAndrew, P. Craig, Talbot, Rachel, Burke, Rosemary, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Meniconi, Mirco, Bellenie, Benjamin R., Hoelder, Swen

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Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket von Lloyd, Matthew G, Huckvale, Rosemary, Cheung, Kwai-Ming J, Rodrigues, Matthew J, Collie, Gavin W, Pierrat, Olivier A, Gatti Iou, Mahad, Carter, Michael, Davis, Owen A, McAndrew, P. Craig, Gunnell, Emma, Le Bihan, Yann-Vaï, Talbot, Rachel, Henley, Alan T, Johnson, Louise D, Hayes, Angela, Bright, Michael D, Raynaud, Florence I, Meniconi, Mirco, Burke, Rosemary, van Montfort, Rob L. M, Rossanese, Olivia W, Bellenie, Benjamin R, Hoelder, Swen

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Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones von Harnden, Alice C., Davis, Owen A., Box, Gary M., Hayes, Angela, Johnson, Louise D., Henley, Alan T., de Haven Brandon, Alexis K., Valenti, Melanie, Cheung, Kwai-Ming J., Brennan, Alfie, Huckvale, Rosemary, Pierrat, Olivier A., Talbot, Rachel, Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, de Klerk, Selby, McAndrew, Peter Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

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Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo von Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

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Abstract 5231: Small-molecule inhibitors of SCF-Skp2-Cks1 ubiquitin E3 ligase stabilize nuclear p27kip1 as a novel therapeutic approach to endometrial cancer von Egbuta, Chinaza, Dubrulle, Julien, Tellechea, Ana, Manzanares, Miguel A., Li, Yunfeng, Duan, Shanshan, Dickson, John K., Meniconi, Mirco, Huang, Kuo-sen, Huang, Xinyan, Shohdy, Nadim, Pagano, Michelle, Hao, Bing, Mancini, Michael A., Gold, Leslie I.

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Exploiting differences in caspase-2 and -3 S 2 subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhi... von Maillard, Michel C., Brookfield, Frederick A., Courtney, Stephen M., Eustache, Florence M., Gemkow, Mark J., Handel, Rebecca K., Johnson, Laura C., Johnson, Peter D., Kerry, Mark A., Krieger, Florian, Meniconi, Mirco, Muñoz-Sanjuán, Ignacio, Palfrey, Jordan J., Park, Hyunsun, Schaertl, Sabine, Taylor, Malcolm G., Weddell, Derek, Dominguez, Celia

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Steroidal Mineralocorticoid Receptor Antagonists: Synthesis and Biology von Yarnold, Christopher, Bainbridge, J. Marie, Boehm, Helen S., Brewer, Mark, Courtney, Stephen, Deboves, Hervé, Di Lucrezia, Raffaella, Giles, Paul, Hamelin, Estelle, Jungmann, Jörn, Leonardi, Amedeo, Meniconi, Mirco, Riva, Carlo, Scheel, Andreas, Selvaratnam, Suganthan, Shanmugathasan, Sakthi, Sironi, Giorgio, Tavecchia, Paolo, Willows, David

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Exploiting differences in caspase-2 and -3 S sub(2 subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2... von Maillard, Michel C, Brookfield, Frederick A, Courtney, Stephen M, Eustache, Florence M, Gemkow, Mark J, Handel, Rebecca K, Johnson, Laura C, Johnson, Peter D, Kerry, Mark A, Krieger, Florian, Meniconi, Mirco, Munoz-Sanjuan, Ignacio, Palfrey, Jordan J, Park, Hyunsun, Schaertl, Sabine, Taylor, Malcolm G, Weddell, Derek, Dominguez, Celia

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Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin:  From a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses von Macchiarulo, Antonio, Costantino, Gabriele, Meniconi, Mirco, Pleban, Karin, Ecker, Gerhard, Bellocchi, Daniele, Pellicciari, Roberto

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The role of electrostatic interaction in the molecular recognition of selective agonists to metabotropic glutamate receptors von Macchiarulo, Antonio, Costantino, Gabriele, Sbaglia, Robert, Aiello, Stefania, Meniconi, Mirco, Pellicciari, Roberto

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BCL6 inhibitors von Rosemary Huckvale, Mirco Meniconi, Matthew Garth Lloyd, Swen Hoelder, Gavin Collie, Kwai Ming Jack Cheung, Alfie Brennan, Benjamin Richard Bellenie, Owen Alexander Davis

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BCL6 INHIBITORS von Davis, Owen Alexander, Lloyd, Matthew Garth, Collie, Gavin, Hoelder, Swen, Bellenie, Benjamin Richard, Huckvale, Rosemary, Meniconi, Mirco, Cheung, Kwai Ming Jack, Brennan, Alfie

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BCL6 inhibitors von CHEUNG, Kwai Ming Jack, HOELDER, Swen, MENICONI, Mirco, HUCKVALE, Rosemary, BELLENIE, Benjamin Richard, COLLIE, Gavin, DAVIS, Owen Alexander, BRENNAN, Alfie, LLOYD, Matthew Garth

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BCL6 INHIBITORS von CHEUNG, Kwai Ming Jack, HOELDER, Swen, MENICONI, Mirco, HUCKVALE, Rosemary, BELLENIE, Benjamin Richard, COLLIE, Gavin, DAVIS, Owen Alexander, BRENNAN, Alfie, LLOYD, Matthew Garth

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BCL6 INHIBITORS von Davis, Owen Alexander, Lloyd, Matthew Garth, Collie, Gavin, Hoelder, Swen, Bellenie, Benjamin Richard, Huckvale, Rosemary, Meniconi, Mirco, Cheung, Kwai Ming Jack, Brennan, Alfie

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HETEROARYL INHIBITORS OF PAD4 von DEVRAJ, Rajesh, RIDGILL, Mark, MENICONI, Mirco, LOKE, Pui, KUMARAVEL, Gnanasambandam, TYE, Heather, MONCK, Nat, NORTH, Carl, LECCI, Cristina

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Heteroaryl inhibitors of PAD4 von Papadopoulos, Kostas, Gadouleau, Elise, Monck, Nat, Beaumont, Edward, Palfrey, Jordan, Tye, Heather, Meniconi, Mirco, Woods, Philip A, Gleave, Laura, Kerry, Philip Stephen, Atton, Holly, Devraj, Rajesh, Kumaravel, Gnanasambandam, Lecci, Cristina

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