Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration von Joshi, Amit U., Minhas, Paras S., Liddelow, Shane A., Haileselassie, Bereketeab, Andreasson, Katrin I., Dorn, Gerald W., Mochly-Rosen, Daria

Volltext

Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy von Haileselassie, Bereketeab, Joshi, Amit U, Minhas, Paras S, Mukherjee, Riddhita, Andreasson, Katrin I, Mochly-Rosen, Daria

Volltext

Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation von Minhas, Paras S., Liu, Ling, Moon, Peter K., Joshi, Amit U., Dove, Christopher, Mhatre, Siddhita, Contrepois, Kevin, Wang, Qian, Lee, Brittany A., Coronado, Michael, Bernstein, Daniel, Snyder, Michael P., Migaud, Marie, Majeti, Ravindra, Mochly-Rosen, Daria, Rabinowitz, Joshua D., Andreasson, Katrin I.

Volltext

Restoring metabolism of myeloid cells reverses cognitive decline in ageing von Minhas, Paras S., Latif-Hernandez, Amira, McReynolds, Melanie R., Durairaj, Aarooran S., Wang, Qian, Rubin, Amanda, Joshi, Amit U., He, Joy Q., Gauba, Esha, Liu, Ling, Wang, Congcong, Linde, Miles, Sugiura, Yuki, Moon, Peter K., Majeti, Ravi, Suematsu, Makoto, Mochly-Rosen, Daria, Weissman, Irving L., Longo, Frank M., Rabinowitz, Joshua D., Andreasson, Katrin I.

Volltext

Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity von Liu, Qingkun, Johnson, Emily M., Lam, Rachel K., Wang, Qian, Bo Ye, Hong, Wilson, Edward N., Minhas, Paras S., Liu, Ling, Swarovski, Michelle S., Tran, Stephanie, Wang, Jing, Mehta, Swapnil S., Yang, Xi, Rabinowitz, Joshua D., Yang, Samuel S., Shamloo, Mehrdad, Mueller, Christoph, James, Michelle L., Andreasson, Katrin I.

Volltext

Soluble TREM2 is elevated in Parkinson's disease subgroups with increased CSF tau von Wilson, Edward N, Swarovski, Michelle S, Linortner, Patricia, Shahid, Marian, Zuckerman, Abigail J, Wang, Qian, Channappa, Divya, Minhas, Paras S, Mhatre, Siddhita D, Plowey, Edward D, Quinn, Joseph F, Zabetian, Cyrus P, Tian, Lu, Longo, Frank M, Cholerton, Brenna, Montine, Thomas J, Poston, Kathleen L, Andreasson, Katrin I

Volltext

Teasing apart NAD+ metabolism in inflammation: commentary on Zhou et al. (2016). Br J Pharmacol 173: 2352–2368 von Moon, Peter, Minhas, Paras

Volltext

Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer's disease related pathology von Joshi, Amit U, Van Wassenhove, Lauren D, Logas, Kelsey R, Minhas, Paras S, Andreasson, Katrin I, Weinberg, Kenneth I, Chen, Che-Hong, Mochly-Rosen, Daria

Volltext

Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies von Minhas, Paras S, Jones, Jeffrey R, Latif-Hernandez, Amira, Sugiura, Yuki, Durairaj, Aarooran S, Wang, Qian, Mhatre, Siddhita D, Uenaka, Takeshi, Crapser, Joshua, Conley, Travis, Ennerfelt, Hannah, Jung, Yoo Jin, Liu, Ling, Prasad, Praveena, Jenkins, Brenita C, Ay, Yeonglong Albert, Matrongolo, Matthew, Goodman, Ryan, Newmeyer, Traci, Heard, Kelly, Kang, Austin, Wilson, Edward N, Yang, Tao, Ullian, Erik M, Serrano, Geidy E, Beach, Thomas G, Wernig, Marius, Rabinowitz, Joshua D, Suematsu, Makoto, Longo, Frank M, McReynolds, Melanie R, Gage, Fred H, Andreasson, Katrin I

Volltext

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models von Wilson, Edward N., Wang, Congcong, Swarovski, Michelle S., Zera, Kristy A., Ennerfelt, Hannah E., Wang, Qian, Chaney, Aisling, Gauba, Esha, Ramos Benitez, Javier A., Le Guen, Yann, Minhas, Paras S., Panchal, Maharshi, Tan, Yuting J., Blacher, Eran, A. Iweka, Chinyere, Cropper, Haley, Jain, Poorva, Liu, Qingkun, Mehta, Swapnil S., Zuckerman, Abigail J., Xin, Matthew, Umans, Jacob, Huang, Jolie, Durairaj, Aarooran S., Serrano, Geidy E., Beach, Thomas G., Greicius, Michael D., James, Michelle L., Buckwalter, Marion S., McReynolds, Melanie R., Rabinowitz, Joshua D., Andreasson, Katrin I.

Volltext

On the promise of glycogen phosphorylase inhibition in acute inflammation von Durairaj, Aarooran Sivakumaran, Minhas, Paras Singh

Volltext

A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity‐dependent synaptic and microglial transcriptomic changes in a late‐stage Alzheimer's mo... von Latif‐Hernandez, Amira, Yang, Tao, Butler, Robert R., Losada, Patricia Moran, Minhas, Paras S., White, Halle, Tran, Kevin C., Liu, Harry, Simmons, Danielle A., Langness, Vanessa, Andreasson, Katrin I., Wyss‐Coray, Tony, Longo, Frank M.

Volltext

Author Correction: Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration von Joshi, Amit U., Minhas, Paras S., Liddelow, Shane A., Haileselassie, Bereketeab, Andreasson, Katrin I., Dorn, Gerald W., Mochly-Rosen, Daria

Volltext

The Dueling Duo: IL10 and TNF Face Off in Microglial Recovery from Endotoxin Challenge von Minhas, Paras Singh, Durairaj, Aarooran Sivakumaran, Andreasson, Katrin I.

Volltext

Passport to pathology: transforming the medical student pathology elective from a passive educational experience to an exciting, immersive clinical rotation von Minhas, Paras S., Enogieru, Imarhia E., Mitchell, Richard N., Mata, Douglas A.

Volltext

Reexamining IFN-γ Stimulation of De Novo NAD+ in Monocyte-Derived Macrophages von Moon, Peter, Minhas, Paras Singh

Volltext

Revisiting IDO and its value as a predictive marker for anti-PD-1 resistance von Moon, Peter Kim, Tran, Stephanie, Minhas, Paras Singh

Volltext

A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation von Li, Li, Conradson, Devon M., Bharat, Vinita, Kim, Min Joo, Hsieh, Chung-Han, Minhas, Paras S., Papakyrikos, Amanda M., Durairaj, Aarooran Sivakumaran, Ludlam, Anthony, Andreasson, Katrin I., Partridge, Linda, Cianfrocco, Michael A., Wang, Xinnan

Volltext

Immersion medicine programme for secondary students von Minhas, Paras S, Kim, Nathan, Myers, Jayson, Caceres, Wendy, Martin, Marina, Singh, Baldeep

Volltext

Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease von Zhang, Liang, Zhang, Song, Maezawa, Izumi, Trushin, Sergey, Minhas, Paras, Pinto, Matthew, Jin, Lee-Way, Prasain, Keshar, Nguyen, Thi D.T., Yamazaki, Yu, Kanekiyo, Takahisa, Bu, Guojun, Gateno, Benjamin, Chang, Kyeong-Ok, Nath, Karl A., Nemutlu, Emirhan, Dzeja, Petras, Pang, Yuan-Ping, Hua, Duy H., Trushina, Eugenia

Volltext