ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia von Zhou, Jianbiao, Yiying Quah, Jessie, Ng, Yvonne, Chooi, Jing-Yuan, Hui-Min Toh, Sabrina, Lin, Baohong, Zea Tan, Tuan, Hosoi, Hiroki, Osato, Motomi, Seet, Qihui, Ooi, Lisa A G, Lindmark, Bertil, McHale, Mark, Chng, Wee-Joo

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Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma von Zhou, Jianbiao, Toh, Sabrina Hui-Min, Tan, Tze King, Balan, Kalpnaa, Lim, Jing Quan, Tan, Tuan Zea, Xiong, Sinan, Jia, Yunlu, Ng, Siok-Bian, Peng, Yanfen, Jeyasekharan, Anand D, Fan, Shuangyi, Lim, Soon Thye, Ong, Chin-Ann Johnny, Ong, Choon Kiat, Sanda, Takaomi, Chng, Wee-Joo

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Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia von Zhou, Jianbiao, Bi, Chonglei, Ching, Ying Qing, Chooi, Jing-Yuan, Lu, Xiao, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Chan, Zit-Liang, Tan, Tuan Zea, Chong, Phyllis Sy, Chng, Wee-Joo

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A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase von Zhou, Jianbiao, Toh, Sabrina Hui-Min, Chan, Zit-Liang, Quah, Jessie Yiying, Chooi, Jing-Yuan, Tan, Tuan Zea, Chong, Phyllis S Y, Zeng, Qi, Chng, Wee-Joo

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Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma von Xiong, Sinan, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Tan, Tuan Zea, Toh, Sabrina Hui-Min, Tang, Nicole Xin Ning, Jia, Yunlu, See, Yi Xiang, Fullwood, Melissa Jane, Sanda, Takaomi, Chng, Wee-Joo

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MMSET I acts as an oncoprotein and regulates GLO1 expression in t(4;14) multiple myeloma cells von Xie, Zhigang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Yang, Dongxiao, Basri, Nurhidayah Binte, Ho, Ying Swan, Chng, Wee Joo

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Non-canonical activation of β-catenin by PRL-3 phosphatase in acute myeloid leukemia von Chong, Phyllis S. Y., Zhou, Jianbiao, Chooi, Jing-Yuan, Chan, Zit-Liang, Toh, Sabrina Hui Min, Tan, Tuan Zea, Wee, Sheena, Gunaratne, Jayantha, Zeng, Qi, Chng, Wee-Joo

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Epigenetic dysregulation of eukaryotic initiation factor 3 subunit E (eIF3E) by lysine methyltransferase REIIBP confers a pro-inflammatory phenotype in t(4;14) myeloma von Chong, Phyllis S Y, Chooi, Jing Yuan, Lim, Sze Lynn Julia, Chung, Tae-Hoon, Brunmeir, Reinhard, Leow, Aaron Chung Yong, Toh, Sabrina Hui Min, Balan, Kalpnaa, Azaman, Muhamad Irfan Bin, Wu, Zhengwei, Subramaniam, Nagavidya, Vardy, Leah A, Chng, Wee-Joo

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Determinants of response to daratumumab in Epstein-Barr virus-positive natural killer and T-cell lymphoma von Mustafa, Nurulhuda, Nee, Adina Huey Fang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Chung, Tae-Hoon, Selvarajan, Viknesvaran, Fan, Shuangyi, Ng, Siok Bian, Poon, Michelle, Chan, Esther, Lee, Joanne, Chee, Yen Lin, Jeyasekharan, Anand D, Zhou, Longen, Yang, Jennifer, Chng, Wee Joo

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NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B von Zhou, Jianbiao, Chooi, Jing-Yuan, Ching, Ying Qing, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Ng, Yvonne, Tan, Tuan Zea, Chng, Wee-Joo

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SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic PTP4A3 through Chromatin Remodeling in t(4;14) Multiple Myeloma von Chong, Phyllis S Y, Chooi, Jing Yuan, Lim, Julia S L, Toh, Sabrina Hui Min, Tan, Tuan Zea, Chng, Wee-Joo

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Super-Enhancer-Driven PPP1R15B As an Oncogenic and Potential Therapeutic Target in Multiple Myeloma von Xiong, Sinan, Zhou, Jianbiao, Tan, Tze King, Toh, Sabrina Hui-Min, Balan, Kalpnaa, Jia, Yunlu, Chung, Tae-Hoon, Sanda, Takaomi, Chng, Wee Joo

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Histone methyltransferase NSD2 activates PKCα to drive metabolic reprogramming and lenalidomide resistance in multiple myeloma von Chong, Phyllis S Y, Chooi, Jing-Yuan, Lim, Julia S L, Leow, Aaron C Y, Toh, Sabrina Hui Min, Azaman, Irfan, Koh, Mun Yee, Teoh, Phaik Ju, Tan, Tuan Zea, Chung, Tae-Hoon, Chng, Wee Joo

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Single-Cell Multi-Omic Analysis Uncovers Comprised Immune Function and Primary Resistance Mechanism in Acute Myeloid Leukemia von Zhou, Jianbiao, Scolnick, Jonathan Adam, Xu, Stacy, Ooi, Melissa, Chia, Priscella Shirley, Toh, Sabrina Hui-Min, Balan, Kalpnaa, Lovci, Michael, Tan, Tuan Zea, Ying, Jen Wei, NG, Chin-Hin, Chng, Wee-Joo

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MMSET I Acts As an Oncoprotein and Regulates GLO1 Expression in T(4;14) Multiple Myeloma Cells von Xie, Zhigang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Chng, Wee Joo

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P-348 ADAR1-regulated cytoplasmic dsRNA-immune sensing pathway is a novel mechanism of lenalidomide resistance in multiple myeloma von Koh, Mun Yee, Chung, Tae-Hoon, Toh, Sabrina Hui Min, Tang, Nicole Xin Ning, Zhou, Jianbiao, Chen, Leilei, Chng, Wee Joo, Teoh, Phaik Ju

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Super-Enhancer-Driven TOX2 Mediates Oncogenesis in Natural Killer/T Cell Lymphoma von Zhou, Jianbiao, Toh, Sabrina Hui Min, Balan, Kalpnaa, Tan, Tze King, Jia, Yunlu, Lim, Jing Quan, Ong, Choon Kiat, Lim, Soon Thye, Tan, Tuan Zea, Ng, Siok-Bian, Sanda, Takaomi, Chng, Wee-Joo

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Non-canonical activation of [beta]-catenin by PRL-3 phosphatase in acute myeloid leukemia von Chong, Phyllis S. Y, Zhou, Jianbiao, Chooi, Jing-Yuan, Chan, Zit-Liang, Toh, Sabrina Hui Min, Tan, Tuan Zea, Wee, Sheena

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CD55 and CD59 Can Limit the Anti-Tumor Efficacy of Daratumumab in Natural Killer/T-Cell Lymphoma von Mustafa, Nurulhuda, Nee, Adina Huey Fang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Hee, Yan Ting, Selvarajan, Viknesvaran, Zhou, Longen, Yang, Jennifer, Chng, Wee Joo

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P-098: Super-enhancer-driven PPP1R15B as an oncogenic and potential therapeutic target in Multiple Myeloma von Xiong, Sinan, Zhou, Jianbiao, Tan, Tze King, Toh, Sabrina Hui-Min, Balan, Kalpnaa, Jia, Yunlu, Chung, Tae-Hoon, Sanda, Takaomi, Chng, Wee-Joo

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