Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models von Yang, Yanping, Yang, Huan, Alcaina, Yago, Puc, Janusz, Birt, Alyssa, Vedvyas, Yogindra, Gallagher, Michael, Alla, Srinija, Riascos, Maria Cristina, McCloskey, Jaclyn E., Du, Karrie, Gonzalez-Valdivieso, Juan, Min, Irene M., de Stanchina, Elisa, Britz, Matt, von Hofe, Eric, Jin, Moonsoo M.

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Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response von Yang, Yanping, Vedvyas, Yogindra, Alcaina, Yago, Son, Ju Y, Min, Irene M, Jin, Moonsoo M

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The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells von Min, Irene M, Pietramaggiori, Giorgio, Kim, Francis S, Passegué, Emmanuelle, Stevenson, Kristen E, Wagers, Amy J

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Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression von Hartford, Suzanne A, Luo, Yunhai, Southard, Teresa L, Min, Irene M, Lis, John T, Schimenti, John C

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Chimeric Antigen Receptor T Cell Therapy Targeting ICAM-1 in Gastric Cancer von Jung, Minkyu, Yang, Yanping, McCloskey, Jaclyn E., Zaman, Marjan, Vedvyas, Yogindra, Zhang, Xianglan, Stefanova, Dessislava, Gray, Katherine D., Min, Irene M., Zarnegar, Raza, Choi, Yoon Young, Cheong, Jae-Ho, Noh, Sung Hoon, Rha, Sun Young, Chung, Hyun Cheol, Jin, Moonsoo M.

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Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells von Breault, David T, Min, Irene M, Carlone, Diana L, Farilla, Loredana G, Ambruzs, Dana M, Henderson, Daniel E, Algra, Selma, Montgomery, Robert K, Wagers, Amy J, Hole, Nicholas

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Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity von Park, Spencer, Shevlin, Enda, Vedvyas, Yogindra, Zaman, Marjan, Park, Susan, Hsu, Yen-Michael S., Min, Irene M., Jin, Moonsoo M.

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Sol-Gel SELEX Circumventing Chemical Conjugation of Low Molecular Weight Metabolites Discovers Aptamers Selective to Xanthine von Bae, Hyunjung, Ren, Shuo, Kang, Jeehye, Kim, Minjung, Jiang, Yuanyuan, Jin, Moonsoo M., Min, Irene M., Kim, Soyoun

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Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration von Greenberg, Jacques, Limberg, Jessica, Verma, Akanksha, Kim, David, Chen, Xiang, Lee, Yeon J, Moore, Maureen D, Ullmann, Timothy M, Thiesmeyer, Jessica W, Loewenstein, Zachary, Chen, Kevin J, Egan, Caitlin E, Stefanova, Dessislava, Bareja, Rohan, Zarnegar, Rasa, Finnerty, Brendan M, Scognamiglio, Theresa, Du, Yi-Chieh Nancy, Elemento, Olivier, Fahey, 3rd, Thomas J, Min, Irene M

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CAR T Therapy Targeting ICAM-1 Eliminates Advanced Human Thyroid Tumors von Min, Irene M, Shevlin, Enda, Vedvyas, Yogindra, Zaman, Marjan, Wyrwas, Brian, Scognamiglio, Theresa, Moore, Maureen D, Wang, Weibin, Park, Susan, Park, Spencer, Panjwani, Suraj, Gray, Katherine D, Tassler, Andrew B, Zarnegar, Rasa, Fahey, 3rd, Thomas J, Jin, Moonsoo M

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Discovering aptamers by cell-SELEX against human soluble growth factors ectopically expressed on yeast cell surface von Meng, Hsien-Wei, Pagano, John M, White, Brian S, Toyoda, Yoshiko, Min, Irene M, Craighead, Harold G, Shalloway, David, Lis, John T, Xiao, Kai, Jin, Moonsoo M

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Manufacturing and preclinical validation of CAR T cells targeting ICAM-1 for advanced thyroid cancer therapy von Vedvyas, Yogindra, McCloskey, Jaclyn E., Yang, Yanping, Min, Irene M., Fahey, Thomas J., Zarnegar, Rasa, Hsu, Yen-Michael S., Hsu, Jing-Mei, Van Besien, Koen, Gaudet, Ian, Law, Ping, Kim, Nak Joon, Hofe, Eric von, Jin, Moonsoo M.

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Ovulated oocytes in adult mice derive from non-circulating germ cells von Jurga, Sara, Min, Irene M, Gosden, Roger, Wagers, Amy J, Eggan, Kevin

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PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer von Gray, Katherine D., McCloskey, Jaclyn E., Vedvyas, Yogindra, Kalloo, Olivia R., El Eshaky, Steve, Yang, Yanping, Shevlin, Enda, Zaman, Marjan, Ullmann, Timothy M., Liang, Heng, Stefanova, Dessislava, Christos, Paul J., Scognamiglio, Theresa, Tassler, Andrew B., Zarnegar, Rasa, Fahey, Thomas J., Jin, Moonsoo M., Min, Irene M.

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Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance von Yang, Yanping, Louie, Raymond, Puc, Janusz, Vedvyas, Yogindra, Alcaina, Yago, Min, Irene M, Britz, Matt, Luciani, Fabio, Jin, Moonsoo M

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CSPG4 Is a Potential Therapeutic Target in Anaplastic Thyroid Cancer von Egan, Caitlin E., Stefanova, Dessislava, Ahmed, Adnan, Raja, Vijay J., Thiesmeyer, Jessica W., Chen, Kevin J., Greenberg, Jacques A., Zhang, Taotao, He, Bing, Finnerty, Brendan M., Zarnegar, Rasa, Jin, Moonsoo M., Scognamiglio, Theresa, Dephoure, Noah, Fahey, Thomas, Min, Irene M.

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Activation of the JAK/STAT Pathway Leads to BRAF Inhibitor Resistance in BRAFV600E Positive Thyroid Carcinoma von Limberg, Jessica, Egan, Caitlin E, Gray, Katherine D, Singh, Mandeep, Loewenstein, Zachary, Yang, Yanping, Riascos, Maria Cristina, Al Asadi, Hala, Safe, Parima, El Eshaky, Steve, Liang, Heng, Ullmann, Timothy M, Wang, Weibin, Li, Wei, Zhang, Tuo, Xiang, Jenny, Stefanova, Dessislava, Jin, Moonsoo M, Zarnegar, Rasa, Fahey, Thomas J, Min, Irene M

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Bispecific CAR T Cells against EpCAM and Inducible ICAM-1 Overcome Antigen Heterogeneity and Generate Superior Antitumor Responses von Yang, Yanping, McCloskey, Jaclyn E., Yang, Huan, Puc, Janusz, Alcaina, Yago, Vedvyas, Yogindra, Gomez Gallegos, Angel A., Ortiz-Sanchez, Elizabeth, de Stanchina, Elisa, Min, Irene M., von Hofe, Eric, Jin, Moonsoo M.

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Sex-Based Clinicopathologic and Survival Differences Among Patients with Pancreatic Neuroendocrine Tumors von Greenberg, Jacques A., Ivanov, Nikolay A, Egan, Caitlin E., Lee, Yeon Joo, Zarnegar, Rasa, Fahey, Thomas J., Finnerty, Brendan M., Min, Irene M.

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Dual inhibition of BRAF and MEK increases expression of sodium iodide symporter in patient-derived papillary thyroid cancer cells in vitro von Ullmann, Timothy M., Liang, Heng, Moore, Maureen D., Al-Jamed, Isra, Gray, Katherine D., Limberg, Jessica, Stefanova, Dessislava, Buicko, Jessica L., Finnerty, Brendan, Beninato, Toni, Zarnegar, Rasa, Min, Irene M., Fahey, Thomas J.

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