Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway von Isaacs, Jennifer S., Jung, Yun-Jin, Mimnaugh, Edward G., Martinez, Alfredo, Cuttitta, Frank, Neckers, Leonard M.

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Endoplasmic Reticulum Vacuolization and Valosin-Containing Protein Relocalization Result from Simultaneous Hsp90 Inhibition by Geldanamycin and Proteasome Inhibition by Velcade von Mimnaugh, Edward G, Xu, Wanping, Vos, Michele, Yuan, Xitong, Neckers, Len

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Chaperone-Dependent E3 Ubiquitin Ligase CHIP Mediates a Degradative Pathway for c-ErbB2/Neu von Xu, Wanping, Marcu, Monica, Yuan, Xitong, Mimnaugh, Edward, Patterson, Cam, Neckers, Len

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Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity von Mimnaugh, Edward G, Xu, Wanping, Vos, Michele, Yuan, Xitong, Isaacs, Jennifer S, Bisht, Kheem S, Gius, David, Neckers, Len

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Sensitivity of Mature ErbB2 to Geldanamycin Is Conferred by Its Kinase Domain and Is Mediated by the Chaperone Protein Hsp90 von Xu, Wanping, Mimnaugh, Edward, Rosser, Meredith F.N., Nicchitta, Christopher, Marcu, Monica, Yarden, Yosef, Neckers, Len

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Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex von Neckers, Len, Xu, Wanping, Yuan, Xitong, Xiang, Zhexin, Mimnaugh, Edward, Marcu, Monica

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Inhibition of heat shock protein HSP90-pp60(v-src) heteroprotein complex formation by benzoquinone ansamycins: Essential role for stress proteins in oncogenic transformation von Whitesell, Luke, Mimnaugh, Edward G, De Costa, Brian, Myers, Charles E

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The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation von Grenert, James P., Sullivan, William P., Fadden, Patrick, Haystead, Timothy A.J., Clark, Jenny, Mimnaugh, Edward, Krutzsch, Henry, Ochel, Hans-Joachim, Schulte, Theodor W., Sausville, Edward, Neckers, Leonard M., Toft, David O.

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Geldanamycin as a potential anti-cancer agent : Its molecular target and biochemical activity von NECKERS, L, SCHULTE, T. W, MIMNAUGH, E

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Rapid Deubiquitination of Nucleosomal Histones in Human Tumor Cells Caused by Proteasome Inhibitors and Stress Response Inducers:  Effects on Replication, Transcription, Translatio... von Mimnaugh, Edward G, Chen, Hou Yu, Davie, James R, Celis, Julio E, Neckers, Len

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Taxol induction of p21WAF1 and p53 requires c-raf-1 von BLAGOSKLONNY, M. V, SCHULTE, T. W, PHYONGMAI NGUYEN, MIMNAUGH, E. G, TREPEL, J, NECKERS, L

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Prevention of cisplatin–DNA adduct repair and potentiation of cisplatin-induced apoptosis in ovarian carcinoma cells by proteasome inhibitors von Mimnaugh, Edward G, Yunmbam, Manasses K, Li, Qingdi, Bonvini, Paolo, Hwang, Sang-Gu, Trepel, Jane, Reed, Eddie, Neckers, Len

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Measuring Ubiquitin Conjugation in Cells von Mimnaugh, Edward G., Neckers, Leonard M.

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Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2 von Xu, Wanping, Mimnaugh, Edward G., Kim, Jung-Sik, Trepel, Jane B., Neckers, Leonard M.

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The measurement of ubiquitin and ubiquitinated proteins von Mimnaugh, Edward G., Bonvini, Paolo, Neckers, Len

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17AAG: low target binding affinity and potent cell activity--finding an explanation von Chiosis, Gabriela, Huezo, Henri, Rosen, Neal, Mimnaugh, Edward, Whitesell, Luke, Neckers, Len

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Possible Role for Serine/Threonine Phosphorylation in the Regulation of the Heteroprotein Complex between the hsp90 Stress Protein and the pp60 Tyrosine Kinase von Edward G. Mimnaugh, Peter J. Worland, Luke Whitesell, Leonard M. Neckers

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Free radicals and anticancer drug resistance: Oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors von Sinha, Birandra K., Mimnaugh, Edward G.

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Differential oxygen radical susceptibility of adriamycin-sensitive and -resistant MCF-7 human breast tumor cells von MIMNAUGH, E. G, DUSRE, L, ATWELL, J, MYERS, C. E

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Adriamycin-enhanced membrane lipid peroxidation in isolated rat nuclei von MIMNAUGH, E. G, KENNEDY, K. A, TRUSH, M. A, SINHA, B. K

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