STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain von Timofeeva, Olga A., Tarasova, Nadya I., Zhang, Xueping, Chasovskikh, Sergey, Cheema, Amrita K., Wang, Honghe, Brown, Milton L., Dritschilo, Anatoly

Volltext

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion von Rahim, Said, Beauchamp, Elspeth M, Kong, Yali, Brown, Milton L, Toretsky, Jeffrey A, Üren, Aykut

Volltext

Radiation Induced Skin Fibrosis (RISF): Opportunity for Angiotensin II-Dependent Intervention von Boothe, Patricia F, Kumar, Vidya P, Kong, Yali, Wang, Kan, Levinson, Howard, Mu, David, Brown, Milton L

Volltext

DIM (3,3′-diindolylmethane) confers protection against ionizing radiation by a unique mechanism von Fan, Saijun, Meng, Qinghui, Xu, Jiaying, Jiao, Yang, Zhao, Lin, Zhang, Xiaodong, Sarkar, Fazlul H., Brown, Milton L., Dritschilo, Anatoly, Rosen, Eliot M.

Volltext

Mechanisms of Unphosphorylated STAT3 Transcription Factor Binding to DNA von Timofeeva, Olga A., Chasovskikh, Sergey, Lonskaya, Irina, Tarasova, Nadya I., Khavrutskii, Lyuba, Tarasov, Sergey G., Zhang, Xueping, Korostyshevskiy, Valeriy R., Cheema, Amrita, Zhang, Lihua, Dakshanamurthy, Sivanesan, Brown, Milton L., Dritschilo, Anatoly

Volltext

High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition von Awad, Ola, Yustein, Jason T, Shah, Preeti, Gul, Naheed, Katuri, Varalakshmi, O'Neill, Alison, Kong, Yali, Brown, Milton L, Toretsky, Jeffrey A, Loeb, David M

Volltext

Total Synthesis of 7‑Hydroxymurrayazolinine, Murrayamine D, and Mahanine via m‑Nitro Group Activated Pyran Annulation von Hou, Shujie, Liu, Yong, Kong, Yali, Brown, Milton L

Volltext

A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model von Rahim, Said, Minas, Tsion, Hong, Sung-Hyeok, Justvig, Sarah, Çelik, Haydar, Kont, Yasemin Saygideger, Han, Jenny, Kallarakal, Abraham T, Kong, Yali, Rudek, Michelle A, Brown, Milton L, Kallakury, Bhaskar, Toretsky, Jeffrey A, Üren, Aykut

Volltext

Exploring Angiotensin II and Oxidative Stress in Radiation-Induced Cataract Formation: Potential for Therapeutic Intervention von Kumar, Vidya P, Kong, Yali, Dolland, Riana, Brown, Sandra R, Wang, Kan, Dolland, Damian, Mu, David, Brown, Milton L

Volltext

AMP-activated protein kinase promotes human prostate cancer cell growth and survival von Park, Hyeon Ung, Suy, Simeng, Danner, Malika, Dailey, Vernon, Zhang, Ying, Li, Henghong, Hyduke, Daniel R, Collins, Brian T, Gagnon, Gregory, Kallakury, Bhaskar, Kumar, Deepak, Brown, Milton L, Fornace, Albert, Dritschilo, Anatoly, Collins, Sean P

Volltext

Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma von Paige, Mikell, Kosturko, George, Bulut, Güllay, Miessau, Matthew, Rahim, Said, Toretsky, Jeffrey A., Brown, Milton L., Üren, Aykut

Volltext

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies von Assefnia, Shahin, Dakshanamurthy, Sivanesan, Guidry Auvil, Jaime M, Hampel, Constanze, Anastasiadis, Panos Z, Kallakury, Bhaskar, Uren, Aykut, Foley, David W, Brown, Milton L, Shapiro, Lawrence, Brenner, Michael, Haigh, David, Byers, Stephen W

Volltext

Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1 von Barber-Rotenberg, Julie S, Selvanathan, Saravana P, Kong, Yali, Erkizan, Hayriye V, Snyder, Tara M, Hong, S Peter, Kobs, Christina L, South, Natalie L, Summer, Steven, Monroe, Philip J, Chruszcz, Maksymilian, Dobrev, Veselin, Tosso, Perrer N, Scher, Lauren J, Minor, Wladek, Brown, Milton L, Metallo, Steven J, Üren, Aykut, Toretsky, Jeffrey A

Volltext

Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase von Holder, Sheldon, Lilly, Michael, Brown, Milton L.

Volltext

Synthesis and structure-activity relationship of boronic acid bioisosteres of combretastatin A-4 as anticancer agents von Kong, Yali, Edler, Michael C., Hamel, Ernest, Britton-Jenkins, Asa R., Gillan, Omar, Mooberry, Susan L., Mu, David, Brown, Milton L.

Volltext

Synthesis of (S)-Jamaicamide C Carboxylic Acid von Graf, Kristin M, Tabor, Martin G, Brown, Milton L, Paige, Mikell

Volltext

Predicting New Indications for Approved Drugs Using a Proteochemometric Method von Dakshanamurthy, Sivanesan, Issa, Naiem T, Assefnia, Shahin, Seshasayee, Ashwini, Peters, Oakland J, Madhavan, Subha, Uren, Aykut, Brown, Milton L, Byers, Stephen W

Volltext

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma von Toretsky, Jeffrey A, Erkizan, Hayriye V, Kong, Yali, Merchant, Melinda, Schlottmann, Silke, Barber-Rotenberg, Julie S, Yuan, Linshan, Abaan, Ogan D, Chou, Tsu-hang, Dakshanamurthy, Sivanesan, Brown, Milton L, Üren, Aykut

Volltext

Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockers von De Oliveira, Eliseu O., Graf, Kristin M., Patel, Manoj K., Baheti, Aparna, Kong, Hye-Sik, MacArthur, Linda H., Dakshanamurthy, Sivanesan, Wang, Kan, Brown, Milton L., Paige, Mikell

Volltext

Asymmetric Synthesis of 2,3-Dihydro-2-arylquinazolin-4-ones: Methodology and Application to a Potent Fluorescent Tubulin Inhibitor with Anticancer Activity von Chinigo, Gary M, Paige, Mikell, Grindrod, Scott, Hamel, Ernest, Dakshanamurthy, Sivanesan, Chruszcz, Maksymilian, Minor, Wladek, Brown, Milton L

Volltext