Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis von Rupaimoole, Rajesha, Lee, Jaehyuk, Haemmerle, Monika, Ling, Hui, Previs, Rebecca A., Pradeep, Sunila, Wu, Sherry Y., Ivan, Cristina, Ferracin, Manuela, Dennison, Jennifer B., Millward, Niki M. Zacharias, Nagaraja, Archana S., Gharpure, Kshipra M., McGuire, Michael, Sam, Nidhin, Armaiz-Pena, Guillermo N., Sadaoui, Nouara C., Rodriguez-Aguayo, Cristian, Calin, George A., Drapkin, Ronny I., Kovacs, Jeffery, Mills, Gordon B., Zhang, Wei, Lopez-Berestein, Gabriel, Bhattacharya, Pratip K., Sood, Anil K.

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Immunogenomic determinants of exceptional response to immune checkpoint inhibition in renal cell carcinoma von Jammihal, Tejas, Saliby, Renee Maria, Labaki, Chris, Soulati, Hanna, Gallegos, Juan, Peris, Arnau, McCurry, Dustin, Yu, Chunlei, Shah, Valisha, Poduval, Deepak, El Zarif, Talal, El Ahmar, Nourhan, Laimon, Yasmin Nabil, Eid, Marc, Sheshdeh, Aseman Bagheri, Krajewski, Katherine M, Büttner, Florian A, Schwab, Matthias, Heng, Daniel, Casellas, Rafael C, Rai, Kunal, Zacharias Millward, Niki M, Msaouel, Pavlos, Karam, Jose, Signoretti, Sabina, Van Allen, Eliezer, Choueiri, Toni K, Braun, David A, Shukla, Sachet A

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Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo von Jeong, Gijin, Lee, Jee-Wook, Gong, Gyeonghyeon, Ko, Hyeji, Choi, Ikjang, Seo, Hyeonglim, Lee, Youngbok, Millward, Niki M. Zacharias, Bhattacharya, Pratip K.

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Chemical reaction-induced multi-molecular polarization (CRIMP) von Lee, Y, Zacharias, N M, Piwnica-Worms, D, Bhattacharya, P K

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Abstract PL07-01: Altered metabolism in leukemic microenvironment von Konopleva, Marina Y., Zal, Tomasz, Millward, Niki M. Zacharias, Cho, Byoung-Sik, Harutyunyan, Karine, Zal, Anna, Mu, Hong, Konoplev, Sergej, Benito, Juliana, Velez, Juliana, Bueso-Ramso, Carlos, Molina, Jennifer, Bhattacharya, Pratip K., Francesco, Maria Emilia Di, Marszalek, Joseph, Andreeff, Michael

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Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia von Zacharias, Niki M, Baran, Natalia, Shanmugavelandy, Sriram S, Lee, Jaehyuk, Lujan, Juliana Velez, Dutta, Prasanta, Millward, Steven W, Cai, Tianyu, Wood, Christopher G, Piwnica-Worms, David, Konopleva, Marina, Bhattacharya, Pratip K

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Directed Evolution of PD-L1-Targeted Affibodies by mRNA Display von Grindel, Brian J., Engel, Brian J., Ong, Justin N., Srinivasamani, Anupallavi, Liang, Xiaowen, Zacharias, Niki M., Bast, Robert C., Curran, Michael A., Takahashi, Terry T., Roberts, Richard W., Millward, Steven W.

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Prolyl Hydroxylase 3 Knockdown Accelerates VHL -Mutant Kidney Cancer Growth In Vivo von Zacharias, Niki M, Wang, Lei, Maity, Tapati, Li, Li, Millward, Steven W, Karam, Jose A, Wood, Christopher G, Navai, Neema

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6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers von Yang, Hailing, Shu, Zhang, Jiang, Yongying, Mao, Weiqun, Pang, Lan, Redwood, Abena, Jeter-Jones, Sabrina L, Jennings, Nicholas B, Ornelas, Argentina, Zhou, Jinhua, Rodriguez-Aguayo, Cristian, Bartholomeusz, Geoffrey, Iles, LaKesla R, Zacharias, Niki M, Millward, Steven W, Lopez-Berestein, Gabriel, Le, Xiao-Feng, Ahmed, Ahmed A, Piwnica-Worms, Helen, Sood, Anil K, Bast, Robert C, Lu, Zhen

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Real‐Time Interrogation of Aspirin Reactivity, Biochemistry, and Biodistribution by Hyperpolarized Magnetic Resonance Spectroscopy von Zacharias, Niki M., Ornelas, Argentina, Lee, Jaehyuk, Hu, Jingzhe, Davis, Jennifer S., Uddin, Nasir, Pudakalakatti, Shivanand, Menter, David G., Karam, Jose A., Wood, Christopher G., Hawk, Ernest T., Kopetz, Scott, Vilar, Eduardo, Bhattacharya, Pratip K., Millward, Steven W.

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PET/MR Imaging of a Lung Metastasis Model of Clear Cell Renal Cell Carcinoma with (2S,4R)-4-[18F]Fluoroglutamine von Pollard, Alyssa C., Paolillo, Vincenzo, Radaram, Bhasker, Qureshy, Sarah, Li, Li, Maity, Tapati, Wang, Lei, Uddin, Md. Nasir, Wood, Christopher G., Karam, Jose A., Pagel, Mark D., Piwnica-Worms, David, Millward, Steven W., Fowlkes, Natalie Wall, Norton, William, Engel, Brian J., Pisaneschi, Federica, Zacharias, Niki M.

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Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models von Ornelas, Argentina, McCullough, Christopher R, Lu, Zhen, Zacharias, Niki M, Kelderhouse, Lindsay E, Gray, Joshua, Yang, Hailing, Engel, Brian J, Wang, Yan, Mao, Weiqun, Sutton, Margie N, Bhattacharya, Pratip K, Bast, Jr, Robert C, Millward, Steven W

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NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors von Pudakalakatti, Shivanand, Audia, Alessandra, Mukhopadhyay, Anirudh, Enriquez, José S., Bourgeois, Dontrey, Tayob, Nabihah, Zacharias, Niki M., Millward, Steven W., Carson, Daniel, Farach-Carson, Mary C., Lang, Frederick F., Heimberger, Amy B., Bhat, Krishna P., Bhattacharya, Pratip K.

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Real-Time MRI-Guided Catheter Tracking Using Hyperpolarized Silicon Particles von Whiting, Nicholas, Hu, Jingzhe, Shah, Jay V., Cassidy, Maja C., Cressman, Erik, Zacharias Millward, Niki, Menter, David G., Marcus, Charles M., Bhattacharya, Pratip K.

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Mammalian Expression and In Situ Biotinylation of Extracellular Protein Targets for Directed Evolution von Grindel, Brian J, Engel, Brian J, Hall, Carolyn G, Kelderhouse, Lindsay E, Lucci, Anthony, Zacharias, Niki M, Takahashi, Terry T, Millward, Steven W

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SMARCB1 regulates the hypoxic stress response in sickle cell trait von Soeung, Melinda, Perelli, Luigi, Chen, Ziheng, Dondossola, Eleonora, Ho, I-Lin, Carbone, Federica, Zhang, Li, Khan, Hania, Le, Courtney N, Zhu, Cihui, Peoples, Michael D, Feng, Ningping, Jiang, Shan, Zacharias, Niki Millward, Minelli, Rosalba, Shapiro, Daniel D, Deem, Angela K, Gao, Sisi, Cheng, Emily H, Lucchetti, Donatella, Walker, Cheryl L, Carugo, Alessandro, Giuliani, Virginia, Heffernan, Timothy P, Viale, Andrea, Tannir, Nizar M, Draetta, Giulio F, Msaouel, Pavlos, Genovese, Giannicola

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Abstract 1247: Targeting neddylation in combination with cytotoxic chemotherapy for the treatment of renal medullary carcinoma von Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Bertocchio, Jean-Philippe, Soeung, Melinda, Rao, Priya, Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Wood, Christopher G., Karam, Jose A., Msaouel, Pavlos

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Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy von Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Karki, Menuka, Bertocchio, Jean‐Philippe, Soeung, Melinda, He, Rong, Westerman, Mary E., Gao, Jianjun, Rao, Priya, Lam, Truong N. A., Jonasch, Eric, Perelli, Luigi, Cheng, Emily H., Carugo, Alessandro, Heffernan, Timothy P., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Karam, Jose A., Msaouel, Pavlos

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Real‐Time Interrogation of Aspirin Reactivity, Biochemistry, and Biodistribution by Hyperpolarized Magnetic Resonance Spectroscopy von Zacharias, Niki M., Ornelas, Argentina, Lee, Jaehyuk, Hu, Jingzhe, Davis, Jennifer S., Uddin, Nasir, Pudakalakatti, Shivanand, Menter, David G., Karam, Jose A., Wood, Christopher G., Hawk, Ernest T., Kopetz, Scott, Vilar, Eduardo, Bhattacharya, Pratip K., Millward, Steven W.

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