Machine learning liver-injuring drug interactions with non-steroidal anti-inflammatory drugs (NSAIDs) from a retrospective electronic health record (EHR) cohort von Datta, Arghya, Flynn, Noah R., Barnette, Dustyn A., Woeltje, Keith F., Miller, Grover P., Swamidass, S. Joshua

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Modeling Epoxidation of Drug-like Molecules with a Deep Machine Learning Network von Hughes, Tyler B, Miller, Grover P, Swamidass, S. Joshua

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Editorial: Advancements in computational studies of drug toxicity von Flynn, Noah R, Miller, Grover P, Swamidass, S Joshua

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Modeling Reactivity to Biological Macromolecules with a Deep Multitask Network von Hughes, Tyler B, Dang, Na Le, Miller, Grover P, Swamidass, S. Joshua

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Lamisil (terbinafine) toxicity: Determining pathways to bioactivation through computational and experimental approaches von Barnette, Dustyn A., Davis, Mary A., Dang, Na L., Pidugu, Anirudh S., Hughes, Tyler, Swamidass, S. Joshua, Boysen, Gunnar, Miller, Grover P.

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CYP2C19 and 3A4 Dominate Metabolic Clearance and Bioactivation of Terbinafine Based on Computational and Experimental Approaches von Davis, Mary A, Barnette, Dustyn A, Flynn, Noah R, Pidugu, Anirudh S, Swamidass, S. Joshua, Boysen, Gunnar, Miller, Grover P

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CYP2E1 hydroxylation of aniline involves negative cooperativity von Hartman, Jessica H., Knott, Katie, Miller, Grover P.

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Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics von Pinson, Anna O., Pouncey, Dakota L., Schleiff, Mary A., Fantegrossi, William E., Prather, Paul L., Radominska-Pandya, Anna, Boysen, Gunnar, Miller, Grover P.

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Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids von Mazur, Anna, Lichti, Cheryl F., Prather, Paul L., Zielinska, Agnieszka K., Bratton, Stacie M., Gallus-Zawada, Anna, Finel, Moshe, Miller, Grover P., Radomińska-Pandya, Anna, Moran, Jeffery H.

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Discovery of Novel Reductive Elimination Pathway for 10-Hydroxywarfarin von Pouncey, Dakota L, Barnette, Dustyn A, Sinnott, Riley W, Phillips, Sarah J, Flynn, Noah R, Hendrickson, Howard P, Swamidass, S Joshua, Miller, Grover P

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The Role of Cytochrome P450 3A4-Mediated Metabolism in Sorafenib and Lapatinib Hepatotoxicity von McGill, Mitchell R., Kaufmann, Yihong, LoBianco, Francesca V., Schleiff, Mary A., Aykin-Burns, Nukhet, Miller, Grover P.

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Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures von Hartman, Jessica H., Letzig, Lynda G., Roberts, Dean W., James, Laura P., Fifer, E.Kim, Miller, Grover P.

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CYP2E1 metabolism of styrene involves allostery von Hartman, Jessica H, Boysen, Gunnar, Miller, Grover P

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Toxicological implications of mitochondrial localization of CYP2E1 von Hartman, Jessica H, Miller, Grover P, Meyer, Joel N

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Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes von Crosby, Samantha V, Ahmed, Izzeldin Y, Osborn, Laura R, Wang, Zeyuan, Schleiff, Mary A, Fantegrossi, William E, Nagar, Swati, Prather, Paul L, Boysen, Gunnar, Miller, Grover P

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Site of Reactivity Models Predict Molecular Reactivity of Diverse Chemicals with Glutathione von Hughes, Tyler B, Miller, Grover P, Swamidass, S. Joshua

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The Role of ERp44 in Maturation of Serotonin Transporter Protein von Freyaldenhoven, Samuel, Li, Yicong, Kocabas, Arif M., Ziu, Enrit, Ucer, Serra, Ramanagoudr-Bhojappa, Raman, Miller, Grover P., Kilic, Fusun

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Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors von Flynn, Noah R., Ward, Michael D., Schleiff, Mary A., Laurin, Corentine M. C., Farmer, Rohit, Conway, Stuart J., Boysen, Gunnar, Swamidass, S. Joshua, Miller, Grover P.

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Elucidation of Distinct Ligand Binding Sites for Cytochrome P450 3A4 von Hosea, Natilie A, Miller, Grover P, Guengerich, F. Peter

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Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam von Barnette, Dustyn A., Schleiff, Mary A., Datta, Arghya, Flynn, Noah, Swamidass, S. Joshua, Miller, Grover P.

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