Kinetic and Structural Studies on the Interaction of Cholinesterases with the Anti-Alzheimer Drug Rivastigmine von Bar-On, P, Millard, C. B, Harel, M, Dvir, H, Enz, A, Sussman, J. L, Silman, I

Volltext

Crystal Structures of Aged Phosphonylated Acetylcholinesterase:  Nerve Agent Reaction Products at the Atomic Level von Millard, Charles B, Kryger, Gitay, Ordentlich, Arie, Greenblatt, Harry M, Harel, Michal, Raves, Mia L, Segall, Yoffi, Barak, Dov, Shafferman, Avigdor, Silman, Israel, Sussman, Joel L

Volltext

Serotype-selective, small-molecule inhibitors of the zinc endopeptidase of botulinum neurotoxin serotype A von Park, Jewn Giew, Sill, Peter C., Makiyi, Edward F., Garcia-Sosa, Alfonso T., Millard, Charles B., Schmidt, James J., Pang, Yuan-Ping

Volltext

Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica von Koellner, G, Kryger, G, Millard, C B, Silman, I, Sussman, J L, Steiner, T

Volltext

Reaction Products of Acetylcholinesterase and VX Reveal a Mobile Histidine in the Catalytic Triad von Millard, Charles B, Koellner, Gertraud, Ordentlich, Arie, Shafferman, Avigdor, Silman, Israel, Sussman, Joel L

Volltext

High-Throughput Assays for Botulinum Neurotoxin Proteolytic Activity: Serotypes A, B, D, and F von Schmidt, James J., Stafford, Robert G., Millard, Charles B.

Volltext

Improved stability of a protein vaccine through elimination of a partially unfolded state von McHugh, Colleen A., Tammariello, Ralph F., Millard, Charles B., Carra, John H.

Volltext

Finding a new vaccine in the ricin protein fold von Olson, Mark A., Carra, John H., Roxas-Duncan, Virginia, Wannemacher, Robert W., Smith, Leonard A., Millard, Charles B.

Volltext

Anticholinesterases: Medical Applications of Neurochemical Principles von Millard, Charles B., Broomfield, Clarence A.

Volltext

Organophosphorus Acid Anhydride Hydrolase Activity in Human Butyrylcholinesterase:  Synergy Results in a Somanase von Millard, Charles B, Lockridge, Oksana, Broomfield, Clarence A

Volltext

A Neutral Molecule in a Cation-binding Site: Specific Binding of a PEG-SH to Acetylcholinesterase from Torpedo californica von Koellner, Gertraud, Steiner, Thomas, Millard, Charles B., Silman, Israel, Sussman, Joel L.

Volltext

A Single Amino Acid Substitution, Gly117His, Confers Phosphotriesterase (Organophosphorus Acid Anhydride Hydrolase) Activity on Human Butyrylcholinesterase von Lockridge, Oksana, Blong, Renee M, Masson, Patrick, Froment, Marie-Thérèse, Millard, Charles B, Broomfield, Clarence A

Volltext

Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones von Millard, Charles B., Shnyrov, Valery L., Newstead, Simon, Shin, Irina, Roth, Esther, Silman, Israel, Weiner, Lev

Volltext

Bis-imidazoles as molecular probes for peripheral sites of the zinc endopeptidase of botulinum neurotoxin serotype A von Merino, Isidro, Thompson, Jason D., Millard, Charles B., Schmidt, James J., Pang, Yuan-Ping

Volltext

Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase von Millard, Charles B, Lockridge, Oksana, Broomfield, Clarence A

Volltext

Integrated Bioassays in Microfluidic Devices: Botulinum Toxin Assays von Mangru, Shakuntala, Bentz, Bryan L., Davis, Timothy J., Desai, Nitin, Stabile, Paul J., Schmidt, James J., Millard, Charles B., Bavari, Sina, Kodukula, Krishna

Volltext

Conformational energy landscape of the acyl pocket loop in acetylcholinesterase: a Monte Carlo-generalized Born model study von Carlacci, Louis, Millard, Charles B., Olson, Mark A.

Volltext

Validation of ELISA for the determination of anti-ricin immunoglobulin G concentration in mouse sera von Lindsey, Changhong Y., Pace-Templeton, Judith G., Millard, Charles B., Wannemacher, Robert W., Hewetson, John F.

Volltext

Alterations in human lymphocyte DNA caused by sulfur mustard can be mitigated by selective inhibitors of poly(ADP-ribose) polymerase von Meier, Henry Louis, Millard, Charles B.

Volltext

Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization von Broomfield, Clarence A., Lockridge, Oksana, Millard, Charles B.

Volltext