Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action von Milicaj, Jozafina, Hassan, Bakar A., Cote, Joy M., Ramirez-Mondragon, Carlos A., Jaunbocus, Nadiya, Rafalowski, Angelika, Patel, Kaelan R., Castro, Colleen D., Muthyala, Ramaiah, Sham, Yuk Y., Taylor, Erika A.

Volltext

Perturbing Lipopolysaccharide Biosynthesis through Inhibition of Heptosyltransferase I von Milicaj, Jozafina

Volltext

Conserved Conformational Hierarchy across Functionally Divergent Glycosyltransferases of the GT-B Structural Superfamily as Determined from Microsecond Molecular Dynamics von Ramirez-Mondragon, Carlos A., Nguyen, Megin E., Milicaj, Jozafina, Hassan, Bakar A., Tucci, Frank J., Muthyala, Ramaiah, Gao, Jiali, Taylor, Erika A., Sham, Yuk Y.

Volltext

Extraction of ADP-Heptose and Kdo2-Lipid A from E. coli Deficient in the Heptosyltransferase I Gene von Milicaj, Jozafina, Castro, Colleen D., Jaunbocus, Nadiya, Taylor, Erika A.

Volltext

Ligand-Induced Conformational and Dynamical Changes in a GT-B Glycosyltransferase: Molecular Dynamics Simulations of Heptosyltransferase | Complexes von Hassan, Bakar A, Milicaj, Jozafina, Ramirez-Mondragon, Carlos Andres, Sham, Yuk Yin, Taylor, Erika A

Volltext

In Vitro and In Silico Explorations of the Protein Conformational Changes of Corynebacterium glutamicum MshA, a Model Retaining GT‑B Glycosyltransferase von Hassan, Bakar A., Milicaj, Jozafina, Tyson, Meka, Karki, Ramesh, Sham, Yuk Y., Frantom, Patrick A., Taylor, Erika A.

Volltext

Ligand-Induced Conformational and Dynamical Changes in a GT‑B Glycosyltransferase: Molecular Dynamics Simulations of Heptosyltransferase I Complexes von Hassan, Bakar A, Milicaj, Jozafina, Ramirez-Mondragon, Carlos Andres, Sham, Yuk Yin, Taylor, Erika A

Volltext

Kinetic Characterization and Computational Modeling of Escherichia coli Heptosyltransferase II: Exploring the Role of Protein Dynamics in Catalysis for GT‑B Glycosyltransferase von Hassan, Bakar A., Liu, Zhiqi A., Milicaj, Jozafina, Kim, Mia S., Tyson, Meka, Sham, Yuk Y., Taylor, Erika A.

Volltext

A General Strategy to Synthesize ADP-7-Azido-heptose and ADP-Azido-mannoses and Their Heptosyltransferase Binding Properties von Li, Tianlei, Tikad, Abdellatif, Fu, Huixiao, Milicaj, Jozafina, Castro, Colleen D, Lacritick, Marine, Pan, Weidong, Taylor, Erika A, Vincent, Stéphane P

Volltext

Extraction of ADP-Heptose and Kdo(2)-Lipid A from E. coli Deficient in the Heptosyltransferase I Gene von Milicaj, Jozafina, Castro, Colleen D., Jaunbocus, Nadiya, Taylor, Erika A.

Volltext

Facile and Adaptable Synthesis of a Prazosin Analogue Library: Bringing Medicinal Chemistry into the Undergraduate Curriculum von Milicaj, Jozafina, Dodda, Vasudeva R, Patel, Kaelan R, Aragon, Ingrid Rodriguez, O’Connell, Timothy, Muthyala, Ramaiah, Taylor, Erika A, Sham, Yuk Y

Volltext