Discovery and hit-to-lead evaluation of piperazine amides as selective, state-dependent NaV1.7 inhibitors von Sparling, Brian A, Yi, S, Able, J, Bregman, H, DiMauro, Erin F, Foti, R S, Gao, H, Guzman-Perez, A, Huang, H, Jarosh, M, Kornecook, T, Ligutti, J, Milgram, B C, Moyer, B D, Youngblood, B, Yu, V L, Weiss, M M

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Discovery and hit-to-lead evaluation of piperazine amides as selective, state-dependent Na V 1.7 inhibitors von Sparling, Brian A, Yi, S, Able, J, Bregman, H, DiMauro, Erin F, Foti, R S, Gao, H, Guzman-Perez, A, Huang, H, Jarosh, M, Kornecook, T, Ligutti, J, Milgram, B C, Moyer, B D, Youngblood, B, Yu, V L, Weiss, M M

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Identification of STX-721, an EGFR exon 20 mutant inhibitor with superior selectivity and a potential best-in-class profile von Pagliarini, R., Milgram, B.C., Borrelli, D.R., Brooijmans, N., Huff, M.R., Ito, T., Jonsson, P., Ladd, B., O’Hearn, E., Wang, W., Kuzmic, P., Bellier, J., Hata, A.N., Guzman-Perez, A., Stuart, D.D.

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Catalytic Conjugate Additions of Carbonyl Anions under Neutral Aqueous Conditions von Myers, Michael C, Bharadwaj, Ashwin R, Milgram, Benjamin C, Scheidt, Karl A

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Discovery and hit-to-lead evaluation of piperazine amides as selective, state-dependent NaV1.7 inhibitorsThe authors declare no competing financial interests.Electronic supplementa... von Sparling, Brian A, Yi, S, Able, J, Bregman, H, DiMauro, Erin F, Foti, R. S, Gao, H, Guzman-Perez, A, Huang, H, Jarosh, M, Kornecook, T, Ligutti, J, Milgram, B. C, Moyer, B. D, Youngblood, B, Yu, V. L, Weiss, M. M

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Discovery and hit-to-lead evaluation of piperazine amides as selective, state-dependent NaV1.7 inhibitors† †The authors declare no competing financial interests. ‡ ‡Electronic supp... von Sparling, Brian A., Yi, S., Able, J., Bregman, H., DiMauro, Erin F., Foti, R. S., Gao, H., Guzman-Perez, A., Huang, H., Jarosh, M., Kornecook, T., Ligutti, J., Milgram, B. C., Moyer, B. D., Youngblood, B., Yu, V. L., Weiss, M. M.

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Efficient Synthesis of Acylsilanes Using Morpholine Amides von Clark, Christopher T, Milgram, Benjamin C, Scheidt, Karl A

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Dietary enrichment counteracts age-associated cognitive dysfunction in canines von Milgram, N.W, Zicker, S.C, Head, E, Muggenburg, B.A, Murphey, H, Ikeda-Douglas, C.J, Cotman, C.W

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Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study von Milgram, N.W., Head, E., Zicker, S.C., Ikeda-Douglas, C.J., Murphey, H., Muggenburg, B., Siwak, C., Tapp, D., Cotman, C.W.

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Total Syntheses of HMP-Y1, Hibarimicinone, and HMP-P1 von Liau, Brian B, Milgram, Benjamin C, Shair, Matthew D

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Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator recons... von KONSTAN, Michael W, DAVIS, Pamela B, OETTE, Sharon M, PAYNE, Jennifer M, MUHAMMAD, Osman, ZIADY, Assem G, MOEN, Robert C, COOPER, Mark J, WAGENER, Jeffrey S, HILLIARD, Kathleen A, STERN, Robert C, MILGRAM, Laura J. H, KOWALCZYK, Tomasz H, HYATT, Susannah L, FINK, Tamara L, GEDEON, Christopher R

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Quantitative Detection of Eight Phthalate Metabolites in Human Urine Using HPLC−APCI-MS/MS von Blount, Benjamin C, Milgram, K. Eric, Silva, Manori J, Malek, Nicole A, Reidy, John A, Needham, Larry L, Brock, John W

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PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data von Bahl, Amit, Brunk, Brian, Crabtree, Jonathan, Fraunholz, Martin J., Gajria, Bindu, Grant, Gregory R., Ginsburg, Hagai, Gupta, Dinesh, Kissinger, Jessica C., Labo, Philip, Li, Li, Mailman, Matthew D., Milgram, Arthur J., Pearson, David S., Roos, David S., Schug, Jonathan, Stoeckert, Christian J., Whetzel, Patricia

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Oxidative damage increases with age in a canine model of human brain aging von Head, E., Liu, J., Hagen, T. M., Muggenburg, B. A., Milgram, N. W., Ames, B. N., Cotman, C. W.

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Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction von Cotman, Carl W, Head, Elizabeth, Muggenburg, Bruce A, Zicker, S, Milgram, Norton W

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Compartmentalized Autocrine Signaling to Cystic Fibrosis Transmembrane Conductance Regulator at the Apical Membrane of Airway Epithelial Cells von Huang, Pingbo, Lazarowski, Eduardo R., Tarran, Robert, Milgram, Sharon L., Boucher, Richard C., Stutts, M. Jackson

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Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging von Tapp, P Dwight, Siwak, Christina T, Estrada, Jimena, Head, Elizabeth, Muggenburg, Bruce A, Cotman, Carl W, Milgram, Norton W

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An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton von Short, Douglas B., Trotter, Kevin W., Reczek, David, Kreda, Silvia M., Bretscher, Anthony, Boucher, Richard C., Stutts, M. Jackson, Milgram, Sharon L.

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Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors von Schenkel, Laurie B., DiMauro, Erin F., Nguyen, Hanh N., Chakka, Nagasree, Du, Bingfan, Foti, Robert S., Guzman-Perez, Angel, Jarosh, Michael, La, Daniel S., Ligutti, Joseph, Milgram, Benjamin C., Moyer, Bryan D., Peterson, Emily A., Roberts, John, Yu, Violeta L., Weiss, Matthew M.

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Uranium Induces Apoptosis and Is Genotoxic to Normal Rat Kidney (NRK-52E) Proximal Cells von Thiébault, Céline, Carrière, Marie, Milgram, Sarah, Simon, Angélique, Avoscan, Laure, Gouget, Barbara

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