Large water-table response to rainfall in a shallow bedrock aquifer having minimal overburden cover von Miles, Owen W., Novakowski, Kent S.

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Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function von Welsh, Gavin I., Hale, Lorna J., Eremina, Vera, Jeansson, Marie, Maezawa, Yoshiro, Lennon, Rachel, Pons, Deborah A., Owen, Rachel J., Satchell, Simon C., Miles, Mervyn J., Caunt, Christopher J., McArdle, Craig A., Pavenstädt, Hermann, Tavaré, Jeremy M., Herzenberg, Andrew M., Kahn, C. Ronald, Mathieson, Peter W., Quaggin, Susan E., Saleem, Moin A., Coward, Richard J.M.

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Alkyne Derivatives of SARS-CoV‑2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine von Brewitz, Lennart, Dumjahn, Leo, Zhao, Yilin, Owen, C. David, Laidlaw, Stephen M., Malla, Tika R., Nguyen, Dung, Lukacik, Petra, Salah, Eidarus, Crawshaw, Adam D., Warren, Anna J., Trincao, Jose, Strain-Damerell, Claire, Carroll, Miles W., Walsh, Martin A., Schofield, Christopher J.

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A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19 von Huo, Jiandong, Mikolajek, Halina, Le Bas, Audrey, Clark, Jordan J., Sharma, Parul, Kipar, Anja, Dormon, Joshua, Norman, Chelsea, Weckener, Miriam, Clare, Daniel K., Harrison, Peter J., Tree, Julia A., Buttigieg, Karen R., Salguero, Francisco J., Watson, Robert, Knott, Daniel, Carnell, Oliver, Ngabo, Didier, Elmore, Michael J., Fotheringham, Susan, Harding, Adam, Moynié, Lucile, Ward, Philip N., Dumoux, Maud, Prince, Tessa, Hall, Yper, Hiscox, Julian A., Owen, Andrew, James, William, Carroll, Miles W., Stewart, James P., Naismith, James H., Owens, Raymond J.

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An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike von Schoof, Michael, Faust, Bryan, Saunders, Reuben A, Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B, Puchades, Cristina, Azumaya, Caleigh M, Kratochvil, Huong T, Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C, Chio, Cynthia M, Merz, Gregory E, Thompson, Michael C, Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A, Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R, Leon, Kristoffer, White, Kris M, Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M, Rizo, Alexandrea N, Moss, Frank, Brilot, Axel F, Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W, Nock, Silke, Liu, Yuwei, Krogan, Nevan J, Ralston, Corie Y, Swaney, Danielle L, García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish

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Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis by the ENIGMA Eating Disorders Working Group von Walton, Esther, Bernardoni, Fabio, Batury, Victoria-Luise, Bahnsen, Klaas, Larivière, Sara, Abbate-Daga, Giovanni, Andres-Perpiña, Susana, Bang, Lasse, Bischoff-Grethe, Amanda, Brooks, Samantha J., Campbell, Iain C., Cascino, Giammarco, Castro-Fornieles, Josefina, Collantoni, Enrico, D’Agata, Federico, Dahmen, Brigitte, Danner, Unna N., Favaro, Angela, Feusner, Jamie D., Frank, Guido K.W., Friederich, Hans-Christoph, Graner, John L., Herpertz-Dahlmann, Beate, Hess, Andreas, Horndasch, Stefanie, Kaplan, Allan S., Kaufmann, Lisa-Katrin, Kaye, Walter H., Khalsa, Sahib S., LaBar, Kevin S., Lavagnino, Luca, Lazaro, Luisa, Manara, Renzo, Miles, Amy E., Milos, Gabriella F., Monteleone, Alessio Maria, Monteleone, Palmiero, Mwangi, Benson, O’Daly, Owen, Pariente, Jose, Roesch, Julie, Schmidt, Ulrike H., Seitz, Jochen, Shott, Megan E., Simon, Joe J., Smeets, Paul A.M., Tamnes, Christian K., Tenconi, Elena, Thomopoulos, Sophia I., van Elburg, Annemarie A., Voineskos, Aristotle N., von Polier, Georg G., Wierenga, Christina E., Zucker, Nancy L., Jahanshad, Neda, King, Joseph A., Thompson, Paul M., Berner, Laura A., Ehrlich, Stefan

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Development of a detection system for gas-phase aromatics and other molecules ionizable by soft X-rays demonstrated using methyl salicylate von Kwak, Dong-Bin, Kim, Seong Chan, Mulholland, George W., Owen, Miles C., Kim, Changhyuk, Lee, Handol, Pui, David Y.H

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Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19 von Salguero, Francisco J., White, Andrew D., Slack, Gillian S., Fotheringham, Susan A., Bewley, Kevin R., Gooch, Karen E., Longet, Stephanie, Humphries, Holly E., Watson, Robert J., Hunter, Laura, Ryan, Kathryn A., Hall, Yper, Sibley, Laura, Sarfas, Charlotte, Allen, Lauren, Aram, Marilyn, Brunt, Emily, Brown, Phillip, Buttigieg, Karen R., Cavell, Breeze E., Cobb, Rebecca, Coombes, Naomi S., Darby, Alistair, Daykin-Pont, Owen, Elmore, Michael J., Garcia-Dorival, Isabel, Gkolfinos, Konstantinos, Godwin, Kerry J., Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J., Hender, Thomas, Ho, Catherine M. K., Kennard, Chelsea L., Knott, Daniel, Leung, Stephanie, Lucas, Vanessa, Mabbutt, Adam, Morrison, Alexandra L., Nelson, Charlotte, Ngabo, Didier, Paterson, Jemma, Penn, Elizabeth J., Pullan, Steve, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Tree, Julia A., Turner, Carrie, Vamos, Edith, Wand, Nadina, Wiblin, Nathan R., Charlton, Sue, Dong, Xiaofeng, Hallis, Bassam, Pearson, Geoffrey, Rayner, Emma L., Nicholson, Andrew G., Funnell, Simon G., Hiscox, Julian A., Dennis, Mike J., Gleeson, Fergus V., Sharpe, Sally, Carroll, Miles W.

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Musculoskeletal injury symptoms among hired Latinx child farmworkers in North Carolina von Quandt, Sara A., Arnold, Taylor J., Talton, Jennifer W., Miles, Christopher M., Mora, Dana C., Arcury, Thomas A., Daniel, Stephanie S.

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Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2 von Bracken, Colton J., Lim, Shion A., Solomon, Paige, Rettko, Nicholas J., Nguyen, Duy P., Zha, Beth Shoshana, Schaefer, Kaitlin, Byrnes, James R., Zhou, Jie, Lui, Irene, Liu, Jia, Pance, Katarina, Zhou, Xin X., Leung, Kevin K., Wells, James A.

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Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region von Barrett, Jeffrey C, Lee, James C, Lees, Charles W, Prescott, Natalie J, Anderson, Carl A, Phillips, Anne, Wesley, Emma, Parnell, Kirstie, Zhang, Hu, Drummond, Hazel, Nimmo, Elaine R, Massey, Dunecan, Blaszczyk, Kasia, Elliott, Timothy, Cotterill, Lynn, Dallal, Helen, Lobo, Alan J, Mowat, Craig, Sanderson, Jeremy D, Jewell, Derek P, Newman, William G, Edwards, Cathryn, Ahmad, Tariq, Mansfield, John C, Satsangi, Jack, Parkes, Miles, Mathew, Christopher G, Donnelly, Peter, Peltonen, Leena, Blackwell, Jenefer M, Bramon, Elvira, Brown, Matthew A, Casas, Juan P, Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S, McCarthy, Mark I, Palmer, Colin N A, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Samani, Nilesh, Trembath, Richard C, Viswanathan, Anath C, Wood, Nicholas, Spencer, Chris C A, Bellenguez, Céline, Davison, Daniel, Freeman, Colin, Strange, Amy, Langford, Cordelia, Hunt, Sarah E, Edkins, Sarah, Gwilliam, Rhian, Blackburn, Hannah, Bumpstead, Suzannah J, Dronov, Serge, Gillman, Matthew, Gray, Emma, Hammond, Naomi, Jayakumar, Alagurevathi, McCann, Owen T, Liddle, Jennifer, Perez, Marc L, Potter, Simon C, Ravindrarajah, Radhi, Ricketts, Michelle, Waller, Matthew, Weston, Paul, Widaa, Sara, Whittaker, Pamela, Attwood, Antony P, Stephens, Jonathan, Sambrook, Jennifer, Ouwehand, Willem H, McArdle, Wendy L, Ring, Susan M, Strachan, David P

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Common variants near MC4R are associated with fat mass, weight and risk of obesity von Day, Ian, Dermitzakis, Emmanouil T, Randall, Joshua C, Weedon, Michael N, Hinney, Anke, Evans, David M, Qi, Lu, Bennett, Amanda J, Munroe, Patricia B, Herrera, Blanca, Johnson, Toby, Elliott, Katherine S, Song, Kijoung, Zeggini, Eleftheria, Cauchi, Stéphane, Teichmann, Sarah A, Lindgren, Cecilia M, Brown, Morris, Sims, Matthew A, Karpe, Fredrik, O'Rahilly, Stephen, Hattersley, Andrew T, Scherag, André, Samani, Nilesh J, Keniry, Andrew, Li, Shengxu, Beckmann, Jacques S, Cooper, Cyrus, Caulfield, Mark J, Owen, Katharine R, Luben, Robert N, McGinnis, Ralph, Ghori, Jilur, Ness, Andrew R, Bochud, Murielle, Jarvelin, Marjo-Riitta, Hebebrand, Johannes, Ong, Ken K, Freathy, Rachel M, McArdle, Wendy L, Potter, Simon, Wareham, Nicholas J, Ganz Vogel, Carla I, Mooser, Vincent, Barroso, Inês, Deloukas, Panos, Waterworth, Dawn M, Bergmann, Sven, Elliott, Paul, Gwilliam, Rhian, Tobias, Jonathan H, Jolley, Jennifer D M, Morris, Andrew D, Loos, Ruth J F, Yuan, Xin, Smith, George Davey, Palmer, Colin N A, Groves, Christopher J, Dina, Christian, Syddall, Holly E, Waeber, Gerard, Zhao, Jing Hua, Sandhu, Manjinder S, Doney, Alex S F, Hunt, Sarah E, Pouta, Anneli, Speliotes, Elizabeth K, Connell, John M, Timpson, Nicholas J, Wallace, Chris, Attwood, Antony P, Hall, Alistair S, Khaw, Kay-Tee, Meyre, David, Vollenweider, Peter, Bingham, Sheila A, Berndt, Sonja I, Hadley, David, Rayner, Nigel W, Frayling, Timothy M, Sadaf Farooqi, I, Hirschhorn, Joel N, Strachan, David P, Inouye, Michael, Papadakis, Konstantinos, Ring, Susan M, Wraight, Vicki L, Willer, Cristen J, Marchini, Jonathan, Uda, Manuela, Nica, Alexandra C, Mangino, Massimo, Soranzo, Nicole, McCarthy, Mark I, De, Subhajyoti, Neville, Matthew J, Prokopenko, Inga, Wheeler, Eleanor, Heid, Iris M, Froguel, Philippe

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Alcohol trait and transcriptional genomic analysis of C57BL/6 substrains von Mulligan, M. K., Ponomarev, I., Boehm, S. L., Owen, J. A., Levin, P. S., Berman, A. E., Blednov, Y. A., Crabbe, J. C., Williams, R. W., Miles, M. F., Bergeson, S. E.

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Gammaherpesvirus latency induces antibody-associated thrombocytopenia in mice von Freeman, Michael L, Burkum, Claire E, Lanzer, Kathleen G, Roberts, Alan D, Pinkevych, Mykola, Itakura, Asako, Kummer, Lawrence W, Szaba, Frank M, Davenport, Miles P, McCarty, Owen J.T, Woodland, David L, Smiley, Stephen T, Blackman, Marcia A

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Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency von Murray, Christopher W, Carr, Maria G, Callaghan, Owen, Chessari, Gianni, Congreve, Miles, Cowan, Suzanna, Coyle, Joseph E, Downham, Robert, Figueroa, Eva, Frederickson, Martyn, Graham, Brent, McMenamin, Rachel, O’Brien, M. Alistair, Patel, Sahil, Phillips, Theresa R, Williams, Glyn, Woodhead, Andrew J, Woolford, Alison J.-A

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Surveillance of Vermont wildlife in 2021–2022 reveals no detected SARS-CoV-2 viral RNA von Despres, Hannah W., Mills, Margaret G., Schmidt, Madaline M., Gov, Jolene, Perez, Yael, Jindrich, Mars, Crawford, Allison M. L., Kohl, Warren T., Rosenblatt, Elias, Kubinski, Hannah C., Simmons, Benjamin C., Nippes, Miles C., Goldenberg, Anne J., Murtha, Kristina E., Nicoloro, Samantha, Harris, Mia J., Feeley, Avery C., Gelinas, Taylor K., Cronin, Maeve K., Frederick, Robert S., Thomas, Matthew, Johnson, Meaghan E., Murphy, James, Lenzini, Elle B., Carr, Peter A., Berger, Danielle H., Mehta, Soham P., Floreani, Christopher J., Koval, Amelia C., Young, Aleah L., Fish, Jess H., Wallace, Jack, Chaney, Ella, Ushay, Grace, Ross, Rebecca S., Vostal, Erin M., Thisner, Maya C., Gonet, Kyliegh E., Deane, Owen C., Pelletiere, Kari R., Rockafeller, Vegas C., Waterman, Madeline, Barry, Tyler W., Goering, Catriona C., Shipman, Sarah D., Shiers, Allie C., Reilly, Claire E., Duff, Alanna M., Madruga, Sarah L., Shirley, David J., Jerome, Keith R., Pérez-Osorio, Ailyn C., Greninger, Alexander L., Fortin, Nick, Mosher, Brittany A., Bruce, Emily A.

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Application of Fragment Screening by X-ray Crystallography to β-Secretase von Murray, Christopher W, Callaghan, Owen, Chessari, Gianni, Cleasby, Anne, Congreve, Miles, Frederickson, Martyn, Hartshorn, Michael J, McMenamin, Rachel, Patel, Sahil, Wallis, Nicola

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How to specify healthcare process improvements collaboratively using rapid, remote consensus-building: a framework and a case study of its application von van der Scheer, Jan W, Woodward, Matthew, Ansari, Akbar, Draycott, Tim, Winter, Cathy, Martin, Graham, Kuberska, Karolina, Richards, Natalie, Kern, Ruth, Dixon-Woods, Mary

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Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency... von Edwards, Philip D, Albert, Jeffrey S, Sylvester, Mark, Aharony, David, Andisik, Donald, Callaghan, Owen, Campbell, James B, Carr, Robin A, Chessari, Gianni, Congreve, Miles, Frederickson, Martyn, Folmer, Rutger H. A, Geschwindner, Stefan, Koether, Gerard, Kolmodin, Karin, Krumrine, Jennifer, Mauger, Russell C, Murray, Christopher W, Olsson, Lise-Lotte, Patel, Sahil, Spear, Nate, Tian, Gaochao

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Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals with Anorexia Nervosa - A Coordinated Analysis by the ENIGMA Eating Disorders Working Group von Walton, Esther, Bernardoni, Fabio, Batury, Victoria-Luise, Bahnsen, Klaas, Larivière, Sara, Abbate-Daga, Giovanni, Andres-Perpiña, Susana, Bang, Lasse, Bischoff-Grethe, Amanda, Brooks, Samantha J., Campbell, Iain C., Cascino, Giammarco, Castro-Fornieles, Josefina, Collantoni, Enrico, D'Agata, Federico, Dahmen, Brigitte, Danner, Unna N., Favaro, Angela, Feusner, Jamie D., Frank, Guido KW, Friederich, Hans-Christoph, Graner, John L., Herpertz-Dahlmann, Beate, Hess, Andreas, Horndasch, Stefanie, Kaplan, Allan S., Kaufmann, Lisa-Katrin, Kaye, Walter H., Khalsa, Sahib S., LaBar, Kevin S., Lavagnino, Luca, Lazaro, Luisa, Manara, Renzo, Miles, Amy E., Milos, Gabriella F., Monteleone Alessio, Maria, Monteleone, Palmiero, Mwangi, Benson, O'Daly, Owen, Pariente, Jose, Roesch, Julie, Schmidt, Ulrike H., Seitz, Jochen, Shott, Megan E., Simon, Joe J., Smeets, Paul A.M., Tamnes, Christian K., Tenconi, Elena, Thomopoulos, Sophia I., van Elburg, Annemarie A.

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