The Immunity‐malignancy equilibrium in multiple myeloma: lessons from oncogenic events in plasma cells von Perini, Tommaso, Materozzi, Maria, Milan, Enrico

Volltext

Editorial: Proteomic and metabolic reprogramming in myeloma cells within the tumor microenvironment von Milan, Enrico, Gullà, Annamaria

Volltext

A novel proteomic signature of osteoclast differentiation unveils the deubiquitinase UCHL1 as a necessary osteoclastogenic driver von Materozzi, Maria, Resnati, Massimo, Facchi, Cecilia, Trudu, Matteo, Orfanelli, Ugo, Perini, Tommaso, Gennari, Luigi, Milan, Enrico, Cenci, Simone

Volltext

TENT5C/FAM46C modulation in vivo reveals a trade-off between antibody secretion and tumor growth in multiple myeloma von Resnati, Massimo, Pennacchio, Sara, Viviani, Lisa, Perini, Tommaso, Materozzi, Maria, Orfanelli, Ugo, Bordini, Jessica, Molteni, Raffaella, Nuvolone, Mario, Da Vià, Matteo, Lazzaroni, Francesca, Bolli, Niccolò, Cenci, Simone, Milan, Enrico

Volltext

The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis von Fucci, Chiara, Resnati, Massimo, Riva, Elena, Perini, Tommaso, Ruggieri, Elena, Orfanelli, Ugo, Paradiso, Francesca, Cremasco, Floriana, Raimondi, Andrea, Pasqualetto, Elena, Nuvolone, Mario, Rampoldi, Luca, Cenci, Simone, Milan, Enrico

Volltext

Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors von Cenci, Simone, Oliva, Laura, Cerruti, Fulvia, Milan, Enrico, Bianchi, Giada, Raule, Mary, Mezghrani, Alexandre, Pasqualetto, Elena, Sitia, Roberto, Cascio, Paolo

Volltext

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling von Zhang, Xing-Ding, Baladandayuthapani, Veerabhadran, Lin, Heather, Mulligan, George, Li, Bin, Esseltine, Dixie-Lee W., Qi, Lin, Xu, Jianliang, Hunziker, Walter, Barlogie, Bart, Usmani, Saad Z., Zhang, Qing, Crowley, John, Hoering, Antje, Shah, Jatin J., Weber, Donna M., Manasanch, Elisabet E., Thomas, Sheeba K., Li, Bing-Zong, Wang, Hui-Han, Zhang, Jiexin, Kuiatse, Isere, Tang, Jin-Le, Wang, Hua, He, Jin, Yang, Jing, Milan, Enrico, Cenci, Simone, Ma, Wen-Cai, Wang, Zhi-Qiang, Davis, Richard Eric, Yang, Lin, Orlowski, Robert Z.

Volltext

Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation von Battista, R Alessia, Resnati, Massimo, Facchi, Cecilia, Ruggieri, Elena, Cremasco, Floriana, Paradiso, Francesca, Orfanelli, Ugo, Giordano, Leone, Bussi, Mario, Cenci, Simone, Milan, Enrico

Volltext

The Autophagic Process Occurs in Human Bone Metastasis and Implicates Molecular Mechanisms Differently Affected by Rab5a in the Early and Late Stages von Maroni, Paola, Bendinelli, Paola, Resnati, Massimo, Matteucci, Emanuela, Milan, Enrico, Desiderio, Maria Alfonsina

Volltext

Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells von Auner, Holger W, Moody, Anne Marie, Ward, Theresa H, Kraus, Marianne, Milan, Enrico, May, Philippa, Chaidos, Aristeidis, Driessen, Christoph, Cenci, Simone, Dazzi, Francesco, Rahemtulla, Amin, Apperley, Jane F, Karadimitris, Anastasios, Dillon, Niall

Volltext

A FAM46C-Dependent Molecular Circuit Modulates Antibody Synthesis and Proliferation in Plasma Cell Dyscrasias von Milan, Enrico, Resnati, Massimo, Riva, Elena, Nuvolone, Mario, Cenci, Simone

Volltext

Autophagy in Plasma Cell Ontogeny and Malignancy von Milan, Enrico, Fabbri, Monica, Cenci, Simone

Volltext

Plasma cells require autophagy for sustainable immunoglobulin production von Pengo, Niccolò, Scolari, Maria, Oliva, Laura, Milan, Enrico, Mainoldi, Federica, Raimondi, Andrea, Fagioli, Claudio, Merlini, Arianna, Mariani, Elisabetta, Pasqualetto, Elena, Orfanelli, Ugo, Ponzoni, Maurilio, Sitia, Roberto, Casola, Stefano, Cenci, Simone

Volltext

The amyloidogenic light chain is a stressor that sensitizes plasma cells to proteasome inhibitor toxicity von Oliva, Laura, Orfanelli, Ugo, Resnati, Massimo, Raimondi, Andrea, Orsi, Andrea, Milan, Enrico, Palladini, Giovanni, Milani, Paolo, Cerruti, Fulvia, Cascio, Paolo, Casarini, Simona, Rognoni, Paola, Touvier, Thierry, Marcatti, Magda, Ciceri, Fabio, Mangiacavalli, Silvia, Corso, Alessandro, Merlini, Giampaolo, Cenci, Simone

Volltext

A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells von Milan, Enrico, Perini, Tommaso, Resnati, Massimo, Orfanelli, Ugo, Oliva, Laura, Raimondi, Andrea, Cascio, Paolo, Bachi, Angela, Marcatti, Magda, Ciceri, Fabio, Cenci, Simone

Volltext

P-204 Targeting TENT5C-associated regulation of antibody synthesis against multiple myeloma von Milan, Enrico, Resnati, Massimo, Pennacchio, Sara, Viviani, Lisa, Perini, Tommaso, Cenci, Simone

Volltext

Targeting the Mitochondrial Protease Clpp Unveils Mitochondrial Vulnerabilities in Multiple Myeloma von Perini, Tommaso, Oliva, Laura, Materozzi, Maria, Del Pizzo, Rossella, Cassina, Laura, Samur, Mehmet K., Orfanelli, Ugo, Milan, Enrico, Boletta, Alessandra, Munshi, Nikhil C, Cenci, Simone

Volltext

HMGB1, an evolving pleiotropic protein critical for cellular and tissue homeostasis: Role in aging and age-related diseases von Ruggieri, Elena, Di Domenico, Erika, Locatelli, Andrea Giacomo, Isopo, Flavio, Damanti, Sarah, De Lorenzo, Rebecca, Milan, Enrico, Musco, Giovanna, Rovere-Querini, Patrizia, Cenci, Simone, Vénéreau, Emilie

Volltext

SAA1 is over-expressed in plasma of non small cell lung cancer patients with poor outcome after treatment with epidermal growth factor receptor tyrosine-kinase inhibitors von Milan, Enrico, Lazzari, Chiara, Anand, Santosh, Floriani, Irene, Torri, Valter, Sorlini, Cristina, Gregorc, Vanesa, Bachi, Angela

Volltext

OAB-028: FAM46C-dependent tuning of endoplasmic reticulum capacity in Multiple Myeloma von Milan, Enrico, Riva, Elena, Fucci, Chiara, Resnati, Massimo, Perini, Tommaso, Cenci, Simone

Volltext