Circulating Nucleosomes and Neutrophil Activation as Risk Factors for Deep Vein Thrombosis von van Montfoort, Maurits L, Stephan, Femke, Lauw, Mandy N, Hutten, Barbara A, Van Mierlo, Gerard J, Solati, Shabnam, Middeldorp, Saskia, Meijers, Joost C.M, Zeerleder, Sacha

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Biomarkers to predict infection and infection‐related complications during chemotherapy‐induced neutropenia in acute myeloid leukaemia: a pilot study von Geer, Annemarie, Zandstra, Judith, Tanck, Michael W. T., Nur, Erfan, Mierlo, Gerard, Jongerius, Ilse, Bruggen, Robin, Zeerleder, Sacha S., Kuijpers, Taco W.

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The relation between fibrinogen level, neutrophil activity and nucleosomes in the onset of disseminated intravascular coagulation in the critically ill von Müller, Marcella C.A., Dujardin, Romein W.G., Thachil, Jecko, Mierlo, Gerard, Zeerleder, Sacha S., Juffermans, Nicole P.

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Nucleosomes and neutrophil activation in sickle cell disease painful crisis von Schimmel, Marein, Nur, Erfan, Biemond, Bart J, van Mierlo, Gerard J, Solati, Shabnam, Brandjes, Dees P, Otten, Hans-Martin, Schnog, John-John, Zeerleder, Sacha

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Activated protein C inhibits neutrophil migration in allergic asthma: a randomised trial von de Boer, J Daan, Berger, Marieke, Majoor, Christof J, Kager, Liesbeth M, Meijers, Joost C M, Terpstra, Sanne, Nieuwland, Rienk, Boing, Anita N, Lutter, René, Wouters, Diana, van Mierlo, Gerard J, Zeerleder, Sacha S, Bel, Elisabeth H, van't Veer, Cornelis, de Vos, Alex F, van der Zee, Jaring S, van der Poll, Tom

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Effect of C1‐inhibitor in adults with mild asthma: A randomized controlled trial von Yang, Jack, Engelen, Tjitske S. R., Haak, Bastiaan W., Bonta, Peter I., Majoor, Christof J., Veer, Cornelis, Vos, Alex F., Kemper, E. Marleen, Lutter, René, Mierlo, Gerard, Zeerleder, Sacha S., Bel, Elisabeth H., Poll, Tom

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Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors von Steenhuis, Maurice, Mierlo, Gerard, Derksen, Ninotska IL, Ooijevaar‐de Heer, Pleuni, Kruithof, Simone, Loeff, Floris L, Berkhout, Lea C, Linty, Federica, Reusken, Chantal, Reimerink, Johan, Hogema, Boris, Zaaijer, Hans, Watering, Leo, Swaneveld, Francis, Gils, Marit J, Bosch, Berend Jan, Ham, S Marieke, Brinke, Anja, Vidarsson, Gestur, Schoot, Ellen C, Rispens, Theo

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S100A8/A9 Is a Marker for the Release of Neutrophil Extracellular Traps and Induces Neutrophil Activation von Sprenkeler, Evelien G G, Zandstra, Judith, van Kleef, Nadine D, Goetschalckx, Ines, Verstegen, Bibian, Aarts, Cathelijn E M, Janssen, Hans, Tool, Anton T J, van Mierlo, Gerard, van Bruggen, Robin, Jongerius, Ilse, Kuijpers, Taco W

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Suppressed IgG4 class switching in dupilumab‐ and TNF inhibitor‐treated patients after mRNA vaccination von Valk, Anika M., Keijser, Jim B. D., Dam, Koos P. J., Stalman, Eileen W., Wieske, Luuk, Steenhuis, Maurice, Kummer, Laura Y. L., Spuls, Phyllis I., Bekkenk, Marcel W., Musters, Annelie H., Post, Nicoline F., Bosma, Angela L., Horváth, Barbara, Hijnen, Dirk‐Jan, Schreurs, Corine R. G., Kempen, Zoé L. E., Killestein, Joep, Volkers, Adriaan G., Tas, Sander W., Boekel, Laura, Wolbink, Gerrit J., Keijzer, Sofie, Derksen, Ninotska I. L., Deelen, Melanie, Mierlo, Gerard, Kuijpers, Taco W., Eftimov, Filip, Ham, S. Marieke, Brinke, Anja, Rispens, Theo

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Interaction of Bordetella pertussis filamentous hemagglutinin with human TLR2: identification of the TLR2-binding domain von Asgarian-Omran, Hossein, Amirzargar, Ali Akbar, Zeerleder, Sacha, Mahdavi, Marzieh, van Mierlo, Gerard, Solati, Shabnam, Jeddi-Tehrani, Mahmood, Rabbani, Hodjatallah, Aarden, Leucien, Shokri, Fazel

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Immunothrombosis and Complement Activation Contribute to Disease Severity and Adverse Outcome in COVID-19 von Ruggeri, Tiphaine, De Wit, Yasmin, Schärz, Noëlia, van Mierlo, Gerard, Angelillo-Scherrer, Anne, Brodard, Justine, Schefold, Joerg C., Hirzel, Cédric, Jongerius, Ilse, Zeerleder, Sacha

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Complement factor H contributes to mortality in humans and mice with bacterial meningitis von Kasanmoentalib, E Soemirien, Valls Serón, Mercedes, Engelen-Lee, Joo Yeon, Tanck, Michael W, Pouw, Richard B, van Mierlo, Gerard, Wouters, Diana, Pickering, Matthew C, van der Ende, Arie, Kuijpers, Taco W, Brouwer, Matthijs C, van de Beek, Diederik

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Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma von van Beek, Anna E, Pouw, Richard B, Brouwer, Mieke C, van Mierlo, Gerard, Geissler, Judy, Ooijevaar-de Heer, Pleuni, de Boer, Martin, van Leeuwen, Karin, Rispens, Theo, Wouters, Diana, Kuijpers, Taco W

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The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients von de Beer, Friso M., Wieske, Luuk, van Mierlo, Gerard, Wouters, Diana, Zeerleder, Sacha, Bos, Lieuwe D., Juffermans, Nicole P., Schultz, Marcus J., van der Poll, Tom, Lagrand, Wim K., Horn, Janneke

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Increased intra- and extracellular granzyme expression in patients with tuberculosis von Garcia-Laorden, M. Isabel, Blok, Dana C, Kager, Liesbeth M, Hoogendijk, Arie J, van Mierlo, Gerard J, Lede, Ivar O, Rahman, Wahid, Afroz, Rumana, Ghose, Aniruddha, Visser, Caroline E, Md Zahed, Abu Shahed, Husain, Md Anwar, Alam, Khan Mashrequl, Chandra Barua, Pravat, Hassan, Mahtabuddin, Hossain, Ahmed, Tayab, Md Abu, Day, Nick, Dondorp, Arjen M, de Vos, Alex F, van der Poll, Tom

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Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes von Keizer, Mischa P, Kamp, Angela, van Mierlo, Gerard, Kuijpers, Taco W, Wouters, Diana

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Sugar Matters: Improving In Vivo Clearance Rate of Highly Glycosylated Recombinant Plasma Proteins for Therapeutic Use von Zeerleder, Sacha, Engel, Ruchira, Zhang, Tao, Roem, Dorina, van Mierlo, Gerard, Wagenaar-Bos, Ineke, van Ham, Sija Marieke, Wuhrer, Manfred, Wouters, Diana, Jongerius, Ilse

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Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice von Stroo, Ingrid, Yang, Jack, Anas, Adam A, de Boer, J Daan, van Mierlo, Gerard, Roem, Dorina, Wouters, Diana, Engel, Ruchira, Roelofs, Joris J T H, van 't Veer, Cornelis, van der Poll, Tom, Zeerleder, Sacha

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Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation von van Osch, Thijs L. J., Nouta, Jan, Derksen, Ninotska I. L., van Mierlo, Gerard, van der Schoot, C. Ellen, Wuhrer, Manfred, Rispens, Theo, Vidarsson, Gestur

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153 Visualizing complement activation and regulation in the tumor microenvironment von van Keulen, Joanne, de Boer, Esther, van Mierlo, Gerard, Kamp, Angela, Paul de Boer, Jan, Kuijpers, Taco, Pouw, Richard

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