Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives von Krueger, A. Chris, Madigan, Darold L., Green, Brian E., Hutchinson, Douglas K., Jiang, Wen W., Kati, Warren M., Liu, Yaya, Maring, Clarence J., Masse, Sherie V., McDaniel, Keith F., Middleton, Tim R., Mo, Hongmei, Molla, Akhteruzzaman, Montgomery, Debra A., Ng, Teresa I., Kempf, Dale J.

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Use of SAM2® Biotin Capture Membrane in Microarrayed Compound Screening (μARCS) Format for Nucleic Acid Polymerization Assays von Xuei, Xiaoling, David, Caroline A., Middleton, Tim R., Lim, Ben, Pithawalla, Ron, Chen, Chih-Ming, Tripathi, Rakesh L., Burns, David J., Warrior, Usha

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IMOS National Reference Stations: a continental-wide physical, chemical and biological coastal observing system von Lynch, Tim P, Morello, Elisabetta B, Evans, Karen, Richardson, Anthony J, Rochester, Wayne, Steinberg, Craig R, Roughan, Moninya, Thompson, Peter, Middleton, John F, Feng, Ming, Sherrington, Robert, Brando, Vittorio, Tilbrook, Bronte, Ridgway, Ken, Allen, Simon, Doherty, Peter, Hill, Katherine, Moltmann, Tim C

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Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995–2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer reg... von Coleman, MP, Prof, Forman, D, PhD, Bryant, H, Prof, Butler, J, MRCOG, Rachet, B, PhD, Maringe, C, MSc, Nur, U, PhD, Tracey, E, MPH, Coory, M, PhD, Hatcher, J, PhD, McGahan, CE, MSc, Turner, D, PhD, Marrett, L, Prof, Gjerstorff, ML, MSc, Johannesen, TB, MD, Adolfsson, J, MD, Lambe, M, MD, Lawrence, G, PhD, Meechan, D, MPH, Morris, EJ, PhD, Middleton, R, PhD, Steward, J, FFPH, Richards, MA, Prof

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Vaccine effectiveness against COVID-19 breakthrough infections in patients with cancer (UKCCEP): a population-based test-negative case-control study von Lee, Lennard Y W, Starkey, Thomas, Ionescu, Maria C, Little, Martin, Tilby, Michael, Tripathy, Arvind R, Mckenzie, Hayley S, Al-Hajji, Youssra, Barnard, Matthew, Benny, Liza, Burnett, Alexander, Cattell, Emma L, Charman, Jackie, Clark, James J, Khan, Sam, Ghafoor, Qamar, Illsley, George, Harper-Wynne, Catherine, Hattersley, Rosie J, Lee, Alvin J X, Leonard, Pauline C, Liu, Justin K H, Kinloch, Emma, Lam, Emily, Murphy, Gillian, Rhodes, Malcolm, Robinson, Kate, Pang, Matthew, Pascoe, Jennifer S, Platt, James R, Potter, Vanessa A, Randle, Amelia, Rigg, Anne S, Robinson, Tim M, Roques, Tom W, Roux, René L, Rozmanowski, Stefan, Tuthill, Mark H, Watts, Isabella, Williams, Sarah, Iveson, Tim, Lee, Siow Ming, Middleton, Gary, Middleton, Mark, Protheroe, Andrew, Fittall, Matthew W, Fowler, Tom, Johnson, Peter

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Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase... von Neoptolemos, John P, Prof, Palmer, Daniel H, Prof, Ghaneh, Paula, Prof, Psarelli, Eftychia E, MSc, Valle, Juan W, MD, Halloran, Christopher M, MD, Faluyi, Olusola, MD, O'Reilly, Derek A, MD, Cunningham, David, Prof, Wadsley, Jonathan, Prof, Darby, Suzanne, MD, Meyer, Tim, Prof, Gillmore, Roopinder, MD, Anthoney, Alan, MD, Lind, Pehr, MD, Glimelius, Bengt, MD, Falk, Stephen, MD, Izbicki, Jakob R, Prof, Middleton, Gary William, MD, Cummins, Sebastian, MD, Ross, Paul J, MD, Wasan, Harpreet, MD, McDonald, Alec, MD, Crosby, Tom, MD, Ma, Yuk Ting, MD, Patel, Kinnari, MD, Sherriff, David, FRCR, Soomal, Rubin, MD, Borg, David, MD, Sothi, Sharmila, MD, Hammel, Pascal, Prof, Hackert, Thilo, MD, Jackson, Richard, PhD, Büchler, Markus W, Prof

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Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer von Valle, Juan, Wasan, Harpreet, Palmer, Daniel H, Cunningham, David, Anthoney, Alan, Maraveyas, Anthony, Madhusudan, Srinivasan, Iveson, Tim, Hughes, Sharon, Pereira, Stephen P, Roughton, Michael, Bridgewater, John

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Open letter to Prime Minister David Cameron on food poverty in the UK von Ashton, John R, Middleton, John, Lang, Tim

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COVID-19: Third dose booster vaccine effectiveness against breakthrough coronavirus infection, hospitalisations and death in patients with cancer: A population-based study von Lee, Lennard Y.W., Ionescu, Maria C., Starkey, Thomas, Little, Martin, Tilby, Michael, Tripathy, Arvind R., Mckenzie, Hayley S., Al-Hajji, Youssra, Appanna, Nathan, Barnard, Matthew, Benny, Liza, Burnett, Alexander, Cattell, Emma L., Clark, James J., Khan, Sam, Ghafoor, Qamar, Panneerselvam, Hari, Illsley, George, Harper-Wynne, Catherine, Hattersley, Rosie J., Lee, Alvin JX, Lomas, Oliver, Liu, Justin KH, McCauley, Amanda, Pang, Matthew, Pascoe, Jennifer S., Platt, James R., Patel, Grisma, Patel, Vijay, Potter, Vanessa A., Randle, Amelia, Rigg, Anne S., Robinson, Tim M., Roques, Tom W., Roux, René L., Rozmanowski, Stefan, Taylor, Harriet, Tuthill, Mark H., Watts, Isabella, Williams, Sarah, Beggs, Andrew, Iveson, Tim, Lee, Siow M., Middleton, Gary, Middleton, Mark, Protheroe, Andrew, Fittall, Matthew W., Fowler, Tom, Johnson, Peter, Kinloch, Emma, Lam, Emily, Murphy, Gillian, Rhodes, Malcolm, Robinson, Kate, Swarup, Sanskriti, Bernhardt, Keeley, Bytyci, Jola, Ying, Yuxin, Johal, Sukhmunni, Sheehan, Remarez

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Associations of Disease-Modifying Therapies With COVID-19 Severity in Multiple Sclerosis von Simpson-Yap, Steve, De Brouwer, Edward, Kalincik, Tomas, Rijke, Nick, Hillert, Jan A., Walton, Clare, Edan, Gilles, Moreau, Yves, Spelman, Tim, Geys, Lotte, Parciak, Tina, Gautrais, Clement, Lazovski, Nikola, Pirmani, Ashkan, Ardeshirdavanai, Amin, Forsberg, Lars, Glaser, Anna, McBurney, Robert, Schmidt, Hollie, Bergmann, Arnfin B., Braune, Stefan, Stahmann, Alexander, Middleton, Rodden, Salter, Amber, Fox, Robert J., van der Walt, Anneke, Butzkueven, Helmut, Alroughani, Raed, Ozakbas, Serkan, Rojas, Juan I., van der Mei, Ingrid, Nag, Nupur, Ivanov, Rumen, Sciascia do Olival, Guilherme, Dias, Alice Estavo, Magyari, Melinda, Brum, Doralina, Mendes, Maria Fernanda, Alonso, Ricardo N., Nicholas, Richard S., Bauer, Johana, Chertcoff, Aníbal Sebastián, Zabalza, Anna, Arrambide, Georgina, Fidao, Alexander, Comi, Giancarlo, Peeters, Liesbet

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Tracking the Evolution of Non–Small-Cell Lung Cancer von Jamal-Hanjani, Mariam, Wilson, Gareth A, McGranahan, Nicholas, Birkbak, Nicolai J, Watkins, Thomas B.K, Veeriah, Selvaraju, Shafi, Seema, Johnson, Diana H, Mitter, Richard, Rosenthal, Rachel, Salm, Max, Horswell, Stuart, Escudero, Mickael, Matthews, Nik, Rowan, Andrew, Chambers, Tim, Moore, David A, Turajlic, Samra, Xu, Hang, Lee, Siow-Ming, Forster, Martin D, Ahmad, Tanya, Hiley, Crispin T, Abbosh, Christopher, Falzon, Mary, Borg, Elaine, Marafioti, Teresa, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M, Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Summers, Yvonne, Shah, Rajesh, Joseph, Leena, Quinn, Anne M, Crosbie, Phil A, Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean A, Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-Sellers, Melanie, Prakash, Vineet, Lester, Jason F, Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Davies, Helen, Dentro, Stefan, Taniere, Philippe, O’Sullivan, Brendan, Lowe, Helen L, Hartley, John A, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Shaw, Jacqui A, Herrero, Javier, Szallasi, Zoltan, Schwarz, Roland F, Stewart, Aengus, Quezada, Sergio A, Le Quesne, John, Van Loo, Peter, Dive, Caroline, Hackshaw, Allan, Swanton, Charles

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Cerebrospinal fluid markers of neuroinflammation in delirium: A role for interleukin-1β in delirium after hip fracture von Cape, Eleanor, Hall, Roanna J, van Munster, Barbara C, de Vries, Annick, Howie, Sarah EM, Pearson, Andrew, Middleton, Scott D, Gillies, Fiona, Armstrong, Ian R, White, Tim O, Cunningham, Colm, de Rooij, Sophia E, MacLullich, Alasdair MJ

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The impact of smoking cessation on multiple sclerosis disease progression von Rodgers, Jeff, Friede, Tim, Vonberg, Frederick W, Constantinescu, Cris S, Coles, Alasdair, Chataway, Jeremy, Duddy, Martin, Emsley, Hedley, Ford, Helen, Fisniku, Leonora, Galea, Ian, Harrower, Timothy, Hobart, Jeremy, Huseyin, Huseyin, Kipps, Christopher M, Marta, Monica, McDonnell, Gavin V, McLean, Brendan, Pearson, Owen R, Rog, David, Schmierer, Klaus, Sharrack, Basil, Straukiene, Agne, Wilson, Heather C, Ford, David V, Middleton, Rod M, Nicholas, Richard

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Blood Metal Levels and Amyotrophic Lateral Sclerosis Risk: A Prospective Cohort von Peters, Susan, Broberg, Karin, Gallo, Valentina, Levi, Michael, Kippler, Maria, Vineis, Paolo, Veldink, Jan, Berg, Leonard, Middleton, Lefkos, Travis, Ruth C., Bergmann, Manuela M., Palli, Domenico, Grioni, Sara, Tumino, Rosario, Elbaz, Alexis, Vlaar, Tim, Mancini, Francesca, Kühn, Tilman, Katzke, Verena, Agudo, Antonio, Goñi, Fernando, Gómez, Jesús‐Humberto, Rodríguez‐Barranco, Miguel, Merino, Susana, Barricarte, Aurelio, Trichopoulou, Antonia, Jenab, Mazda, Weiderpass, Elisabete, Vermeulen, Roel

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The impact of healthcare systems on the clinical diagnosis and disease-modifying treatment usage in relapse-onset multiple sclerosis: a real-world perspective in five registries ac... von Nicholas, Richard, Rodgers, Jeff, Witts, James, Lerede, Annalaura, Friede, Tim, Hillert, Jan, Forsberg, Lars, Glaser, Anna, Manouchehrinia, Ali, Ramanujam, Ryan, Spelman, Tim, Klyve, Pernilla, Drahota, Jiri, Horakova, Dana, Joensen, Hanna, Pontieri, Luigi, Magyari, Melinda, Ellenberger, David, Stahmann, Alexander, Butzkueven, Helmut, Van Der Walt, Anneke, Bezlyak, Vladimir, Lines, Carol, Middleton, Rod

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Severe acute myositis and myocarditis on initiation of 6-weekly pembrolizumab post-COVID-19 mRNA vaccination von Watson, Robert A, Ye, Weiyu, Taylor, Chelsea A, Jungkurth, Elsita, Cooper, Rosalin, Tong, Orion, James, Tim, Shine, Brian, Hofer, Monika, Jenkins, Damian, Pell, Robert, Ieremia, Eleni, Jones, Stephanie, Maldonado-Perez, David, Roberts, Ian S D, Coupe, Nicholas, Middleton, Mark R, Payne, Miranda J, Fairfax, Benjamin P

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Immune complex glomerulonephritis of suspected iatrogenic origin in five Japanese Black calves von GOSSELIN, Véronique BERNIER, KIM, Dae Y., NAGY, Dusty W., SHOEMAKE, Brian M., SHAW, Daniel P., ROYAL, Angela B., EVANS, Tim J., MIDDLETON, John R.

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Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer von Lawler, Mark, Alsina, Deborah, Adams, Richard A, Anderson, Annie S, Brown, Gina, Fearnhead, Nicola S, Fenwick, Stephen W, Halloran, Stephen P, Hochhauser, Daniel, Hull, Mark A, Koelzer, Viktor H, McNair, Angus G K, Monahan, Kevin J, Näthke, Inke, Norton, Christine, Novelli, Marco R, Steele, Robert J C, Thomas, Anne L, Wilde, Lisa M, Wilson, Richard H, Tomlinson, Ian

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Asymptomatic internal carotid artery stenosis and cerebrovascular risk stratification von Nicolaides, Andrew N., MS, FRCS, PhD (Hon), Kakkos, Stavros K., MD, MSc, PhD, DIC, Kyriacou, Efthyvoulos, BSc, PhD, Griffin, Maura, MSc, DIC, PhD, Sabetai, Michael, MD, FRCS, PhD, Thomas, Dafydd J., MD, PhD, Tegos, Thomas, MD, PhD, Geroulakos, George, MD, PhD, Labropoulos, Nicos, PhD, DIC, RVT, Doré, Caroline J., BSc, Morris, Tim P., MSc, Naylor, Ross, MD, FRCS, Abbott, Anne L., MB, BS, FRACP, PhD

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People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population von WINNEY, Bruce, BOUMERTIT, Abdelhamid, TONKS, Susan, XIAOFENG YANG, CHESHIRE, James, LONGLEY, Paul, MATEOS, Pablo, GROOM, Alexandra, RELTON, Caroline, TIM BISHOP, D, BLACK, Kathryn, NORTHWOOD, Emma, DAY, Tammy, PARKINSON, Louise, FRAYLING, Timothy M, STEELE, Anna, SAMPSON, Julian R, KING, Turi, DIXON, Ron, MIDDLETON, Derek, JENNINGS, Barbara, BOWDEN, Rory, DONNELLY, Peter, DAVISON, Dan, BODMER, Walter, ECHETA, Chikodi, EVSEEVA, Irina, HUTNIK, Katarzyna, LESLIE, Stephen, NICODEMUS, Kristin, ROYRVIK, Ellen C

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