Abstract 616: The novel α-Gal-based immunotherapy AGI-134 invokes CD8+ T cell-mediated immunity by driving tumor cell destruction, phagocytosis and tumor-associated antigen cross-p... von Middleton, Jenny L., Schulz, Oliver, Charlemagne, Amber, Kristian, Sascha A., Shaw, Stephen Michael

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Managing Incidental Thyroid Nodules Detected on Imaging: White Paper of the ACR Incidental Thyroid Findings Committee von Hoang, Jenny K., MBBS, Langer, Jill E., MD, Middleton, William D., MD, Wu, Carol C., MD, Hammers, Lynwood W., DO, Cronan, John J., MD, Tessler, Franklin N., MD, CM, Grant, Edward G., MD, Berland, Lincoln L., MD

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Thyroid Ultrasound Reporting Lexicon: White Paper of the ACR Thyroid Imaging, Reporting and Data System (TIRADS) Committee von Grant, Edward G., MD, Tessler, Franklin N., MD, Hoang, Jenny K., MBBS, Langer, Jill E., MD, Beland, Michael D., MD, Berland, Lincoln L., MD, Cronan, John J., MD, Desser, Terry S., MD, Frates, Mary C., MD, Hamper, Ulrike M., MD, Middleton, William D., MD, Reading, Carl C., MD, Scoutt, Leslie M., MD, Stavros, A. Thomas, MD, Teefey, Sharlene A., MD

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Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction von Kaitu’u-Lino, Tu’uhevaha J., MacDonald, Teresa M., Cannon, Ping, Nguyen, Tuong-Vi, Hiscock, Richard J., Haan, Nick, Myers, Jenny E., Hastie, Roxanne, Dane, Kirsten M., Middleton, Anna L., Bittar, Intissar, Sferruzzi-Perri, Amanda N., Pritchard, Natasha, Harper, Alesia, Hannan, Natalie J., Kyritsis, Valerie, Crinis, Nick, Hui, Lisa, Walker, Susan P., Tong, Stephen

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Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data von Wright, Caroline F, Dr, Fitzgerald, Tomas W, MS, Jones, Wendy D, MBBS, Clayton, Stephen, MRes, McRae, Jeremy F, PhD, van Kogelenberg, Margriet, PhD, King, Daniel A, MD, Ambridge, Kirsty, BSc, Barrett, Daniel M, BSc, Bayzetinova, Tanya, BSc, Bevan, A Paul, PhD, Bragin, Eugene, MSc, Chatzimichali, Eleni A, PhD, Gribble, Susan, PhD, Jones, Philip, MSc, Krishnappa, Netravathi, MSc, Mason, Laura E, BSc, Miller, Ray, PhD, Morley, Katherine I, PhD, Parthiban, Vijaya, PhD, Prigmore, Elena, PhD, Rajan, Diana, MSc, Sifrim, Alejandro, PhD, Swaminathan, G Jawahar, PhD, Tivey, Adrian R, MSc, Middleton, Anna, PhD, Parker, Michael, Prof, Carter, Nigel P, PhD, Barrett, Jeffrey C, PhD, Hurles, Matthew E, PhD, FitzPatrick, David R, Prof, Firth, Helen V, DM

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ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee von Tessler, Franklin N., MD, CM, Middleton, William D., MD, Grant, Edward G., MD, Hoang, Jenny K., MBBS, Berland, Lincoln L., MD, Teefey, Sharlene A., MD, Cronan, John J., MD, Beland, Michael D., MD, Desser, Terry S., MD, Frates, Mary C., MD, Hammers, Lynwood W., DO, Hamper, Ulrike M., MD, Langer, Jill E., MD, Reading, Carl C., MD, Scoutt, Leslie M., MD, Stavros, A. Thomas, MD

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Inhibition of WEE1 Is Effective in TP53 - and RAS -Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring von Seligmann, Jenny F, Fisher, David J, Brown, Louise C, Adams, Richard A, Graham, Janet, Quirke, Philip, Richman, Susan D, Butler, Rachel, Domingo, Enric, Blake, Andrew, Yates, Emma, Braun, Michael, Collinson, Fiona, Jones, Rob, Brown, Ewan, de Winton, Emma, Humphrey, Timothy C, Parmar, Mahesh, Kaplan, Richard, Wilson, Richard H, Seymour, Matthew, Maughan, Timothy S

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Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy von Abou Jamra, Rami, Accogli, Andrea, Amburgey, Kimberly, Basinger, Alice A., Ceulemans, Sophia, Charles, Perrine, McRae, Jeremy F., Rajan, Diana, Ambridge, Kirsty, Jones, Philip, Jones, Wendy D., Ahmed, Munaza, Anjum, Uruj, Armstrong, Ruth, Barnicoat, Angela, Bennett, Chris, Blair, Edward, Blyth, Moira, Bourdon, Louise, Brady, Angela, Burn, John, Canham, Natalie, Cilliers, Deirdre, Clayton-Smith, Jill, Coates, Andrea, Cooper, Nicola, Dabir, Tabib, Davies, Sally, Dean, John, Devlin, Gemma, Donnai, Dian, Donnelly, Carina, Evans, Karenza, Fendick, Tina, Goodship, Judith, Green, Andrew, Harrison, Lucy, Holden, Simon, Jarvis, Joanna, Johnson, Diana, Jones, Elizabeth, Kumar, V. K. Ajith, Lachlan, Katherine, Langman, Caroline, Maye, Una, McMullan, Dominic J., McWilliam, Catherine, Metcalfe, Kay, Norman, Andrew, Ogilvie, Caroline, Park, Soo-Mi, Phipps, Julie, Prescott, Katrina, Procter, Annie, Purnell, Hellen, Ross, Alison, Sampson, Julian, Shannon, Nora, Skitt, Zara, Stewart, Fiona, Stewart, Helen, Swaminathan, Ganesh Jawahar, Taylor, Cat, Tein, Mark, Treacy, Becky, Vandersteen, Anthony, Wallwark, Sarah, Waters, Jonathon, Weber, Astrid, Whiteford, Margo, Widaa, Sara, Wilcox, Sarah, Wilkinson, Emily, Parker, Michael, FitzPatrick, David R., Demurger, Florence, Eiset, Saga Elise, Ferrarini, Alessandra, Haack, Tobias B., Hashim, Mona, Jonasson, Amy R., Kok, Fernando, Marcelis, Carlo L.M., McWalter, Kirsty, Mercimek-Andrews, Saadet, Person, Richard, Ramelli, Gian Paolo, Rauch, Anita, Sanchez-Valle, Amarilis, Sattar, Shifteh, Saunders, Carol, Steindl, Katharina, Syrbe, Steffen, Taylor, Jenny C., Trauner, Doris A., Vogel, Ida, Widjaja, Elysa, Zak, Jaroslav, Banka, Siddharth, Rodan, Lance H.

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Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial von Adams, Richard A, Fisher, David J, Graham, Janet, Seligmann, Jenny F, Seymour, Matthew, Kaplan, Richard, Yates, Emma, Parmar, Mahesh, Richman, Susan D, Quirke, Philip, Butler, Rachel, Brown, Ewan, Collinson, Fiona, Falk, Stephen, Wasan, Harpreet, Shiu, Kai-Keen, Middleton, Gary, Samuel, Leslie, Wilson, Richard H, Brown, Louise C, Maughan, Timothy S

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Pravastatin for early‐onset pre‐eclampsia: a randomised, blinded, placebo‐controlled trial von Ahmed, A, Williams, DJ, Cheed, V, Middleton, LJ, Ahmad, S, Wang, K, Vince, AT, Hewett, P, Spencer, K, Khan, KS, Daniels, JP, Barber, Katherine, Kilby, Mark, Knox, Ellen, Sellman, Tara, Trinham, Paula, Tuffnell, Derek, Jones, Vicky, Syson, Jennifer, Shah, Neil, Deeks, Laurie, Carter, Wendy, Dorman, Ed, Thomas, Susannah, Harrington, Deborah, Higgins, Nicola, Wilmott‐Powell, Mirriam, Simpson, Nigel, Dolby, Vivian, Bricker, Leanne, Walkinshaw, Steve, Houghton, Gillian, Longworth, Heather, Williamson, Catherine, Dhanjal, Mandish, Noori, Muna, Machirori, Mavis, Howard, Richard, Murray, Rebecca, Weist, Sarah, Denison, Fiona, Crawford, Isobel, Robson, Stephen, Allan, Carly, Myers, Jenny, Bernatavicius, Giovanna, Moorhead, Lynsey, Chappell, Lucy, Nelson‐Piercy, Catherine, Williams, David, Daley, Rebecca, Rosas, Miguel, Greer, Ian, Vitek, Libor, Shennan, Andy, Marlow, Neil, Barnard, Ann Marie, Thornton, Jim, Rennie, Janet, Peacock, Janet, Gao Smith, Fang, Hyde, Carolyn, Crawford, Isobel, Cudmore, Melissa, Furmston, Alex, Fulcher, Leanne, Homer, Leanne, Howman, Andrew, Hilken, Nicholas, Brown, Stephen

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Circulating Tissue Factor Pathway Inhibitor (TFPI) is increased preceding preeclampsia diagnosis and in established preeclampsia von MacDonald, Teresa M., Tong, Stephen, Myers, Jenny, Cannon, Ping, Nguyen, Tuong-Vi, Keenan, Emerson, Murray, Elizabeth, Harper, Alesia, Pritchard, Natasha, Hannan, Natalie J., Dane, Kirsten M., Middleton, Anna L., Kyritsis, Valerie P., Walker, Susan P., Kaitu’u-Lino, Tu'uhevaha J.

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O20 Advanced melanoma is associated with distinct circulating B-cell profiles enriched with immunoregulatory and autoreactive features von Willsmore, Zena, Crescioli, Silvia, Booth, Lucy, Laddach, Roman, Yorke, Rozalyn, Harris, Robert , Chauhan, Jitesh, Chenoweth, Alicia , Adams, Rebecca , Osborn, Gabriel, Di Meo, Ashley , Prassas, Ioannis, Geh, Jenny L C, Patel, Akshay J  , Middleton, Gary W, MacKenzie Ross, Alastair D  , Healey, Ciaran, Diamandis, Eleftherios P, Sinha, Khushboo, Wu, Yin, Whittaker, Sean J, Perucha, Esperanza, Papa, Sophie, Lacy, Katie E  , Karagiannis, Sophia N

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The National COVID‐19 Clinical Evidence Taskforce: pregnancy and perinatal guidelines von Homer, Caroline SE, Roach, Vijay, Cusack, Leila, Giles, Michelle L, Whitehead, Clare, Burton, Wendy, Downton, Teena, Gleeson, Glenda, Gordon, Adrienne, Hose, Karen, Hunt, Jenny, Kitschke, Jackie, McDonnell, Nolan, Middleton, Philippa, Oats, Jeremy JN, Shand, Antonia W, Wilton, Kellie, Vogel, Joshua, Elliott, Julian, McGloughlin, Steven, McDonald, Steve J, White, Heath, Cheyne, Saskia, Turner, Tari

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A community-sourced glossary of open scholarship terms von Parsons, Sam, Azevedo, Flávio, Guay, Samuel, Shahim, Owen N., Govaart, Gisela H., Norris, Emma, O’Mahony, Aoife, Parker, Adam J., Todorovic, Ana, Garcia-Pelegrin, Elias, Lazić, Aleksandra, Middleton, Sara L., Valentini, Beatrice, McCuaig, Joanne, Baker, Bradley J., Collins, Elizabeth, Lonsdorf, Tina B., Lim, Michele C., Vanek, Norbert, Kovacs, Marton, Rishi, Sonia, Miranda, Jacob F., Jaquiery, Matt, Agostini, Valeria, Stewart, Andrew J., Izydorczak, Kamil, Ashcroft-Jones, Sarah, Hartmann, Helena, Ingham, Madeleine, Vasilev, Martin R., Dechterenko, Filip, Albayrak-Aydemir, Nihan, Yang, Yu-Fang, LaPlume, Annalise A., Wolska, Julia K., Henderson, Emma L., Zaneva, Mirela, Farrar, Benjamin G., Mounce, Ross, Kalandadze, Tamara, Li, Wanyin, Xiao, Qinyu, Ross, Robert M., Yeung, Siu Kit, Liu, Meng, Vandegrift, Micah L., Kekecs, Zoltan, Baum, Myriam A., Williams, Emily A., Assaneea, Asma A., Bret, Amélie, Cashin, Aidan G., Ballou, Nick, Dumbalska, Tsvetomira, Kern, Bettina M. J., Melia, Claire R., Arendt, Beatrix, Vineyard, Gerald H., Pickering, Jade S., Evans, Thomas R., Laverty, Catherine, Woodward, Eliza A., Roche, Dominique G., Rinke, Eike M., Reid, Graham, Garcia-Garzon, Eduardo, Verheyen, Steven, Blake, Ashley R., Cockcroft, Jamie P., Micheli, Leticia, Bret, Brice Beffara, Flack, Zoe M., Szaszi, Barnabas, Weinmann, Markus, Lecuona, Oscar, Schmidt, Birgit, Ngiam, William X., Francis, Shannon, Gall, Brett J., Paul, Mariella, Keating, Connor T., Grose-Hodge, Magdalena, Bartlett, James E., Iley, Bethan J., Spitzer, Lisa, Pownall, Madeleine, Graham, Christopher J., Wingen, Tobias, Terry, Jenny, Oliveira, Catia Margarida F., Millager, Ryan A., Fox, Kerry J., AlDoh, Alaa, Hart, Alexander, van den Akker, Olmo R., Feldman, Gilad, Pomareda, Christina, Krautter, Kai, Al-Hoorie, Ali H., Aczel, Balazs

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Development of a bioavailability‐based risk assessment framework for nickel in Southeast Asia and Melanesia von Garman, Emily R, Schlekat, Christian E, Middleton, Ellie, Merrington, Graham, Peters, Adam, Smith, Ross, Stauber, Jenny L, Leung, Kenneth MY, Gissi, Francesca, Binet, Monique T, Adams, Merrin S, Gillmore, Megan L, Golding, Lisa A, Jolley, Dianne, Wang, Zhen, Reichelt‐Brushett, Amanda

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Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study von Kasperavičiūtė, Dalia, Catarino, Claudia B., Heinzen, Erin L., Depondt, Chantal, Cavalleri, Gianpiero L., Caboclo, Luis O., Tate, Sarah K., Jamnadas-Khoda, Jenny, Chinthapalli, Krishna, Clayton, Lisa M.S., Shianna, Kevin V., Radtke, Rodney A., Mikati, Mohamad A., Gallentine, William B., Husain, Aatif M., Alhusaini, Saud, Leppert, David, Middleton, Lefkos T., Gibson, Rachel A., Johnson, Michael R., Matthews, Paul M., Hosford, David, Heuser, Kjell, Amos, Leslie, Ortega, Marcos, Zumsteg, Dominik, Wieser, Heinz-Gregor, Steinhoff, Bernhard J., Krämer, Günter, Hansen, Jörg, Dorn, Thomas, Kantanen, Anne-Mari, Gjerstad, Leif, Peuralinna, Terhi, Hernandez, Dena G., Eriksson, Kai J., Kälviäinen, Reetta K., Doherty, Colin P., Wood, Nicholas W., Pandolfo, Massimo, Duncan, John S., Sander, Josemir W., Delanty, Norman, Goldstein, David B., Sisodiya, Sanjay M.

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Misinterpretation of the American College of Radiology White Paper on Managing Incidental Thyroid Nodules von Hoang, Jenny K., Langer, Jill E., Middleton, William D., Wu, Carol C., Hammers, Lynnwood W., Cronan, John J., Tessler, Franklin N., Grant, Edward G., Berland, Lincoln L.

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HLA-A, -B, -C, and -DRB1 genotyping and haplotype frequencies for a Hong Kong Chinese population of 7595 individuals von Kwok, Janette, Guo, Mengbiao, Yang, Wanling, Lee, C.K., Ho, Jenny, Tang, W.H., Chan, Y.S., Middleton, Derek, Lu, L.W., Chan, Godfrey C.F.

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High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation von Tran, Jenny N., Günther, Oliver P., Sherwood, Karen R., Fenninger, Franz, Allan, Lenka L., Lan, James, Sapir-Pichhadze, Ruth, Duquesnoy, Rene, Claas, Frans, Marsh, Steven G. E., McMaster, W. Robert, Keown, Paul A.

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HLA-A, -B and -DRB1 genotyping and haplotype frequencies of 3892 cord blood units in the Hong Kong Chinese Cord Blood Registry von Kwok, Janette, Guo, Mengbiao, Yang, Wanling, Lee, C.K., Chan, N.K., Ho, Jenny, Tang, W.H., Chan, Y.S., Middleton, Derek, Lu, L.W., Chan, Godfrey C.F.

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