Creation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis von Ogawa, Noriyuki, Kimura, Takehide, Umehara, Fumi, Katayama, Yuki, Nagai, Go, Suzuki, Keiko, Aisaka, Kazuo, Maruyama, Yukie, Itoh, Takafumi, Hashimoto, Wataru, Murata, Kousaku, Ichimura, Michio

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In Vitro and in Vivo Antitrypanosomal Activitiy of Two Microbial Metabolites, KS-505a and Alazopeptin von Ishiyama, Aki, Otoguro, Kazuhiko, Namatame, Miyuki, Nishihara, Aki, Furusawa, Toshiaki, Masuma, Rokuro, Shiomi, Kazuro, Takahashi, Yoko, Ichimura, Michio, Yamada, Haruki, Ōmura, Satoshi

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Differential Effects of PDE4 Inhibitors on Cortical Neurons and T-Lymphocytes von Hirose, Ryo, Manabe, Haruhiko, Yanagawa, Koji, Ohshima, Etsuo, Ichimura, Michio

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YCM1008A, a Novel Ca2+-Signaling Inhibitor, Produced by Fusarium sp. YCM1008 von Koizumi, Fumito, Fukumitsu, Naomi, Zhao, Jinrong, Chanklan, Ruthada, Miyakawa, Tokichi, Kawahara, Shoko, Iwamoto, Shin, Suzuki, Makoto, Kakita, Shingo, Rahayu, Endang S, Hosokawa, Seijiro, Tatsuta, Kuniaki, Ichimura, Michio

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Conformational significance of EH21A1–A4, phenolic derivatives of geldanamycin, for Hsp90 inhibitory activity von Onodera, Hideyuki, Kaneko, Masami, Takahashi, Yuichi, Uochi, Yumiko, Funahashi, Jun, Nakashima, Takayuki, Soga, Shiro, Suzuki, Makoto, Ikeda, Shunichi, Yamashita, Yoshinori, Rahayu, Endang S., Kanda, Yutaka, Ichimura, Michio

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Potent and Selective Inhibitors of Platelet-Derived Growth Factor Receptor Phosphorylation. 3. Replacement of Quinazoline Moiety and Improvement of Metabolic Polymorphism of 4-[4-(... von Matsuno, Kenji, Ushiki, Junko, Seishi, Takashi, Ichimura, Michio, Giese, Neill A, Yu, Jin-Chen, Takahashi, Shusuke, Oda, Shoji, Nomoto, Yuji

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Potent and Selective Inhibitors of Platelet-Derived Growth Factor Receptor Phosphorylation. 1. Synthesis, Structure−Activity Relationship, and Biological Effects of a New Class of... von Matsuno, Kenji, Ichimura, Michio, Nakajima, Takao, Tahara, Keiko, Fujiwara, Shigeki, Kase, Hiroshi, Ushiki, Junko, Giese, Neill A, Pandey, Anjali, Scarborough, Robert M, Lokker, Nathalie A, Yu, Jin-Chen, Irie, Junko, Tsukuda, Eiji, Ide, Shin-ichi, Oda, Shoji, Nomoto, Yuji

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Drug Discovery Research for Microbial Metabolites von Ichimura, Michio

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Potent and Selective Inhibitors of PDGF Receptor Phosphorylation. 2. Synthesis, Structure Activity Relationship, Improvement of Aqueous Solubility, and Biological Effects of 4-[4-(... von Matsuno, Kenji, Nakajima, Takao, Ichimura, Michio, Giese, Neill A, Yu, Jin-Chen, Lokker, Nathalie A, Ushiki, Junko, Ide, Shin-ichi, Oda, Shoji, Nomoto, Yuji

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Unique binding pocket for KW-4679 in the histamine H1 receptor von NONAKA, H, OTAKI, S, OHSHIMA, E, KONO, M, KASE, H, OHTA, K, FUKUI, H, ICHIMURA, M

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Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. Part 4: structure–activity relationships for substituents on the quinazoline moiety of 4... von Matsuno, Kenji, Seishi, Takashi, Nakajima, Takao, Ichimura, Michio, Giese, Neill A, Yu, Jin-Chen, Oda, Shoji, Nomoto, Yuji

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Isoforms of JSAP1 scaffold protein generated through alternative splicing von Ito, Michihiko, Akechi, Mizuho, Hirose, Ryo, Ichimura, Michio, Takamatsu, Nobuhiko, Xu, Ping, Nakabeppu, Yusaku, Tadayoshi, Shiba, Yamamoto, Ken-ichi, Yoshioka, Katsuji

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Adenosine A2A receptor enhances GABAA-mediated IPSCs in the rat globus pallidus von Shindou, Tomomi, Mori, Akihisa, Kase, Hiroshi, Ichimura, Michio

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KF31327, a new potent and selective inhibitor of cyclic nucleotide phosphodiesterase 5 von Hirose, Ryo, Okumura, Hiroshi, Yoshimatsu, Akiko, Irie, Junko, Onoda, Yasuo, Nomoto, Yuji, Takai, Haruki, Ohno, Tetsuji, Ichimura, Michio

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Duocarmycins, Potent Antitumor Antibiotics Produced by Streptomyces sp. Structures and Chemistry von YASUZAWA, Tohru, MUROI, Ken'ichi, ICHIMURA, Michio, TAKAHASHI, Isami, OGAWA, Tatsuhiro, TAKAHASHI, Keiichi, SANO, Hiroshi, SAITOH, Yutaka

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DUOCARMYCIN SA, A NEW ANTITUMOR ANTIBIOTIC FROM STREPTOMYCES SP von ICHIMURA, MICHIO, OGAWA, TATSUHIRO, TAKAHASHI, KEI-ICHI, KOBAYASHI, EIJI, KAWAMOTO, ISAO, YASUZAWA, TOHRU, TAKAHASHI, ISAMI, NAKANO, HIROFUMI

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KW‐3902, a selective high affinity antagonist for adenosine A1 receptors von Nonakay, Hiromi, Ichimura, Michio, Takeda, Masami, Kanda, Tomoyuki, Shimada, Junichi, Suzuki, Fumio, Kase, Hiroshi

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Studies of Cardiotonic Agents. 8. Synthesis and Biological Activities of Optically Active 6-(4-(Benzylamino)-7-quinazolinyl)-4,5-dihydro-5-methyl- 3(2H)-pyridazinone (KF15232) von Nomoto, Yuji, Takai, Haruki, Ohno, Tetsuji, Nagashima, Ken, Yao, Kozo, Yamada, Koji, Kubo, Kazuhiro, Ichimura, Michio, Mihara, Akira, Kase, Hiroshi

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Adenosine A 2A receptor enhances GABA A ‐mediated IPSCs in the rat globus pallidus von Shindou, Tomomi, Mori, Akihisa, Kase, Hiroshi, Ichimura, Michio

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Presynaptic adenosine A2A receptors enhance GABAergic synaptic transmission via a cyclic AMP dependent mechanism in the rat globus pallidus von Shindou, Tomomi, Nonaka, Hiromi, Richardson, Peter J, Mori, Akihisa, Kase, Hiroshi, Ichimura, Michio

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