Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells von Kuntz, Elodie M, Baquero, Pablo, Michie, Alison M, Dunn, Karen, Tardito, Saverio, Holyoake, Tessa L, Helgason, G Vignir, Gottlieb, Eyal

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The discrete roles of individual FOXO transcription factor family members in B-cell malignancies von Lees, Jamie, Hay, Jodie, Moles, Michael W, Michie, Alison M

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The role of mTOR-mediated signaling in the regulation of cellular migration von Holroyd, Ailsa K., Michie, Alison M.

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Death-associated protein kinase (DAPK) and signal transduction: regulation in cancer von Michie, Alison M, McCaig, Alison M, Nakagawa, Rinako, Vukovic, Milica

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CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells von Sinclair, Amy, Park, Laura, Shah, Mansi, Drotar, Mark, Calaminus, Simon, Hopcroft, Lisa E.M., Kinstrie, Ross, Guitart, Amelie V., Dunn, Karen, Abraham, Sheela A., Sansom, Owen, Michie, Alison M., Machesky, Laura, Kranc, Kamil R., Graham, Gerard J., Pellicano, Francesca, Holyoake, Tessa L.

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CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression von Tarafdar, Anuradha, Hopcroft, Lisa E.M., Gallipoli, Paolo, Pellicano, Francesca, Cassels, Jennifer, Hair, Alan, Korfi, Koorosh, Jørgensen, Heather G., Vetrie, David, Holyoake, Tessa L., Michie, Alison M.

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Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells von Rattigan, Kevin M., Brabcova, Zuzana, Sarnello, Daniele, Zarou, Martha M., Roy, Kiron, Kwan, Ryan, de Beauchamp, Lucie, Dawson, Amy, Ianniciello, Angela, Khalaf, Ahmed, Kalkman, Eric R., Scott, Mary T., Dunn, Karen, Sumpton, David, Michie, Alison M., Copland, Mhairi, Tardito, Saverio, Gottlieb, Eyal, Vignir Helgason, G.

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Targeting quiescent leukemic stem cells using second generation autophagy inhibitors von Baquero, Pablo, Dawson, Amy, Mukhopadhyay, Arunima, Kuntz, Elodie M., Mitchell, Rebecca, Olivares, Orianne, Ianniciello, Angela, Scott, Mary T., Dunn, Karen, Nicastri, Michael C., Winkler, Jeffrey D., Michie, Alison M., Ryan, Kevin M., Halsey, Christina, Gottlieb, Eyal, Keaney, Erin P., Murphy, Leon O., Amaravadi, Ravi K., Holyoake, Tessa L., Helgason, G. Vignir

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Dasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12 von McCaig, Alison M, Cosimo, Emilio, Leach, Michael T, Michie, Alison M

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IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors von Wiesheu, Robert, Edwards, Sarah C, Hedley, Ann, Hall, Holly, Tosolini, Marie, Fares da Silva, Marcelo Gregorio Filho, Sumaria, Nital, Castenmiller, Suzanne M, Wardak, Leyma, Optaczy, Yasmin, Lynn, Amy, Hill, David G, Hayes, Alan J, Hay, Jodie, Kilbey, Anna, Shaw, Robin, Whyte, Declan, Walsh, Peter J, Michie, Alison M, Graham, Gerard J, Manoharan, Anand, Halsey, Christina, Blyth, Karen, Wolkers, Monika C, Miller, Crispin, Pennington, Daniel J, Jones, Gareth W, Fournie, Jean-Jacques, Bekiaris, Vasileios, Coffelt, Seth B

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Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease von Scott, Mary T., Liu, Wei, Mitchell, Rebecca, Clarke, Cassie J., Kinstrie, Ross, Warren, Felix, Almasoudi, Hassan, Stevens, Thomas, Dunn, Karen, Pritchard, John, Drotar, Mark E., Michie, Alison M., Jørgensen, Heather G., Higgins, Brian, Copland, Mhairi, Vetrie, David

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The MYC–NFATC2 axis maintains the cell cycle and mitochondrial function in acute myeloid leukaemia cells von Patterson, Shaun D., Massett, Matthew E., Huang, Xu, Jørgensen, Heather G., Michie, Alison M.

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Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells von Donnelly, Hannah, Ross, Ewan, Xiao, Yinbo, Hermantara, Rio, Taqi, Aqeel F., Doherty-Boyd, W. Sebastian, Cassels, Jennifer, Tsimbouri, Penelope. M., Dunn, Karen M., Hay, Jodie, Cheng, Annie, Meek, R. M. Dominic, Jain, Nikhil, West, Christopher, Wheadon, Helen, Michie, Alison M., Peault, Bruno, West, Adam G., Salmeron-Sanchez, Manuel, Dalby, Matthew J.

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Nfix expression critically modulates early B lymphopoiesis and myelopoiesis von O'Connor, Caitríona, Campos, Joana, Osinski, Jason M, Gronostajski, Richard M, Michie, Alison M, Keeshan, Karen

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A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival von Massett, Matthew E., Monaghan, Laura, Patterson, Shaun, Mannion, Niamh, Bunschoten, Roderick P., Hoose, Alex, Marmiroli, Sandra, Liskamp, Robert M. J., Jørgensen, Heather G., Vetrie, David, Michie, Alison M., Huang, Xu

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mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia von Malik, Natasha, Hay, Jodie, Almuhanna, Hassan N. B., Dunn, Karen M., Lees, Jamie, Cassels, Jennifer, Li, Jiatian, Nakagawa, Rinako, Sansom, Owen J., Michie, Alison M.

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Editorial: Special Issue on Innovative Multi-Disciplinary Approaches for Precision Studies in Leukemia von Marmiroli, Sandra, Huang, Xu, Serafin, Valentina, Michie, Alison M.

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Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro‐survival microenvironmental... von MCCaig, Alison M., Cosimo, Emilio, Leach, Michael T., Michie, Alison M.

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mTORC1 activity is essential for erythropoiesis and B cell lineage commitment von Malik, Natasha, Dunn, Karen M., Cassels, Jennifer, Hay, Jodie, Estell, Christopher, Sansom, Owen J., Michie, Alison M.

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AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival von Cosimo, Emilio, Tarafdar, Anuradha, Moles, Michael W, Holroyd, Ailsa K, Malik, Natasha, Catherwood, Mark A, Hay, Jodie, Dunn, Karen M, Macdonald, Alan M, Guichard, Sylvie M, O'Rourke, Declan, Leach, Michael T, Sansom, Owen J, Cosulich, Sabina C, McCaig, Alison M, Michie, Alison M

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