The role of mTOR-mediated signaling in the regulation of cellular migration von Holroyd, Ailsa K., Michie, Alison M.

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Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro‐survival microenvironmental... von MCCaig, Alison M., Cosimo, Emilio, Leach, Michael T., Michie, Alison M.

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Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells von Kuntz, Elodie M, Baquero, Pablo, Michie, Alison M, Dunn, Karen, Tardito, Saverio, Holyoake, Tessa L, Helgason, G Vignir, Gottlieb, Eyal

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Regulation of thymocyte differentiation: pre-TCR signals and β-selection von Michie, Alison M, Zúñiga-Pflücker, Juan Carlos

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The discrete roles of individual FOXO transcription factor family members in B-cell malignancies von Lees, Jamie, Hay, Jodie, Moles, Michael W, Michie, Alison M

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Subcellular Fractionation of Primary Chronic Lymphocytic Leukemia Cells to Monitor Nuclear/Cytoplasmic Protein Trafficking von Hay, Jodie, Moles, Michael W, Cassels, Jennifer, Michie, Alison M

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Modulation of PKC‐α promotes lineage reprogramming of committed B lymphocytes von Nakagawa, Rinako, Vukovic, Milica, Cosimo, Emilio, Michie, Alison M.

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Death-associated protein kinase (DAPK) and signal transduction: regulation in cancer von Michie, Alison M, McCaig, Alison M, Nakagawa, Rinako, Vukovic, Milica

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CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells von Sinclair, Amy, Park, Laura, Shah, Mansi, Drotar, Mark, Calaminus, Simon, Hopcroft, Lisa E.M., Kinstrie, Ross, Guitart, Amelie V., Dunn, Karen, Abraham, Sheela A., Sansom, Owen, Michie, Alison M., Machesky, Laura, Kranc, Kamil R., Graham, Gerard J., Pellicano, Francesca, Holyoake, Tessa L.

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CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression von Tarafdar, Anuradha, Hopcroft, Lisa E.M., Gallipoli, Paolo, Pellicano, Francesca, Cassels, Jennifer, Hair, Alan, Korfi, Koorosh, Jørgensen, Heather G., Vetrie, David, Holyoake, Tessa L., Michie, Alison M.

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Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells von Rattigan, Kevin M., Brabcova, Zuzana, Sarnello, Daniele, Zarou, Martha M., Roy, Kiron, Kwan, Ryan, de Beauchamp, Lucie, Dawson, Amy, Ianniciello, Angela, Khalaf, Ahmed, Kalkman, Eric R., Scott, Mary T., Dunn, Karen, Sumpton, David, Michie, Alison M., Copland, Mhairi, Tardito, Saverio, Gottlieb, Eyal, Vignir Helgason, G.

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Targeting quiescent leukemic stem cells using second generation autophagy inhibitors von Baquero, Pablo, Dawson, Amy, Mukhopadhyay, Arunima, Kuntz, Elodie M., Mitchell, Rebecca, Olivares, Orianne, Ianniciello, Angela, Scott, Mary T., Dunn, Karen, Nicastri, Michael C., Winkler, Jeffrey D., Michie, Alison M., Ryan, Kevin M., Halsey, Christina, Gottlieb, Eyal, Keaney, Erin P., Murphy, Leon O., Amaravadi, Ravi K., Holyoake, Tessa L., Helgason, G. Vignir

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IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors von Wiesheu, Robert, Edwards, Sarah C, Hedley, Ann, Hall, Holly, Tosolini, Marie, Fares da Silva, Marcelo Gregorio Filho, Sumaria, Nital, Castenmiller, Suzanne M, Wardak, Leyma, Optaczy, Yasmin, Lynn, Amy, Hill, David G, Hayes, Alan J, Hay, Jodie, Kilbey, Anna, Shaw, Robin, Whyte, Declan, Walsh, Peter J, Michie, Alison M, Graham, Gerard J, Manoharan, Anand, Halsey, Christina, Blyth, Karen, Wolkers, Monika C, Miller, Crispin, Pennington, Daniel J, Jones, Gareth W, Fournie, Jean-Jacques, Bekiaris, Vasileios, Coffelt, Seth B

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Dasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12 von McCaig, Alison M, Cosimo, Emilio, Leach, Michael T, Michie, Alison M

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Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease von Scott, Mary T., Liu, Wei, Mitchell, Rebecca, Clarke, Cassie J., Kinstrie, Ross, Warren, Felix, Almasoudi, Hassan, Stevens, Thomas, Dunn, Karen, Pritchard, John, Drotar, Mark E., Michie, Alison M., Jørgensen, Heather G., Higgins, Brian, Copland, Mhairi, Vetrie, David

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The MYC–NFATC2 axis maintains the cell cycle and mitochondrial function in acute myeloid leukaemia cells von Patterson, Shaun D., Massett, Matthew E., Huang, Xu, Jørgensen, Heather G., Michie, Alison M.

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Nfix expression critically modulates early B lymphopoiesis and myelopoiesis von O'Connor, Caitríona, Campos, Joana, Osinski, Jason M, Gronostajski, Richard M, Michie, Alison M, Keeshan, Karen

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Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells von Donnelly, Hannah, Ross, Ewan, Xiao, Yinbo, Hermantara, Rio, Taqi, Aqeel F., Doherty-Boyd, W. Sebastian, Cassels, Jennifer, Tsimbouri, Penelope. M., Dunn, Karen M., Hay, Jodie, Cheng, Annie, Meek, R. M. Dominic, Jain, Nikhil, West, Christopher, Wheadon, Helen, Michie, Alison M., Peault, Bruno, West, Adam G., Salmeron-Sanchez, Manuel, Dalby, Matthew J.

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mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia von Malik, Natasha, Hay, Jodie, Almuhanna, Hassan N. B., Dunn, Karen M., Lees, Jamie, Cassels, Jennifer, Li, Jiatian, Nakagawa, Rinako, Sansom, Owen J., Michie, Alison M.

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A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival von Massett, Matthew E., Monaghan, Laura, Patterson, Shaun, Mannion, Niamh, Bunschoten, Roderick P., Hoose, Alex, Marmiroli, Sandra, Liskamp, Robert M. J., Jørgensen, Heather G., Vetrie, David, Michie, Alison M., Huang, Xu

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