Identification of MK-944a:  A Second Clinical Candidate from the Hydroxylaminepentanamide Isostere Series of HIV Protease Inhibitors von Dorsey, Bruce D, McDonough, Colleen, McDaniel, Stacey L, Levin, Rhonda B, Newton, Christina L, Hoffman, Jacob M, Darke, Paul L, Zugay-Murphy, Joan A, Emini, Emilio A, Schleif, William A, Olsen, David B, Stahlhut, Mark W, Rutkowski, Carrie A, Kuo, Lawrence C, Lin, Jiunn H, Chen, I-W, Michelson, Stuart R, Holloway, M. Katharine, Huff, Joel R, Vacca, Joseph P

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Affinity purification of the HIV-1 protease von Heimbach, Jill C., Garsky, Victor M., Michelson, Stuart R., Dixon, Richard A.F., Sigal, Irving S., Darke, Paul L.

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4-Substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors von Hartman, George D, Halczenko, Wasyl, Smith, Robert L, Sugrue, Michael F, Mallorga, Pierre J, Michelson, Stuart R, Randall, William C, Schwam, Harvey, Sondey, John M

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Nonpeptide oxytocin antagonists: Analogs of L-371,257 with improved potency von Williams, Peter D., Bock, Mark G., Evans, Ben E., Freidinger, Roger M., Gallicchio, Steven N., Guidotti, Maribeth T., Jacobson, Marlene A., Kuo, Michelle S., Levy, Michelle R., Lis, Edward V., Michelson, Stuart R., Pawluczyk, Joseph M., Perlow, Debra S., Pettibone, Douglas J., Quigley, Amy G., Reiss, Duane R., Salvatore, Christopher, Stauffer, Kenneth J., Woyden, Carla J.

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Inhibitors of glycolic acid oxidase. 4-Substituted 3-hydroxy-1H-pyrrole-2,5-dione derivatives von Rooney, C. S, Randall, W. C, Streeter, K. B, Ziegler, C, Cragoe, E. J, Schwam, H, Michelson, S. R, Williams, H. W. R, Eichler, E

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(Acyloxy)alkyl carbamates as novel bioreversible prodrugs for amines: increased permeation through biological membranes von Alexander, J, Cargill, R, Michelson, S R, Schwam, H

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3-Substituted thieno[2,3-b][1,4]thiazine-6-sulfonamides. A novel class of topically active carbonic anhydrase inhibitors von Hunt, Cecilia A, Mallorga, Pierre J, Michelson, Stuart R, Schwam, Harvey, Sondey, John M, Smith, Robert L, Sugrue, Michael F, Shepard, Kenneth L

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Thieno[2,3-b]furan-2-sulfonamides as topical carbonic anhydrase inhibitors von Hartman, George D, Halczenko, Wasyl, Prugh, John D, Smith, Robert L, Sugrue, Michael F, Mallorga, Pierre, Michelson, Stuart R, Randall, William C, Schwam, Harvey, Sondey, John M

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Inhibitors of glycolic acid oxidase. 4-Substituted-2,4-dioxobutanoic acid derivatives von Williams, H. W. R., Eichler, E., Randall, W. C., Rooney, C. S., Cragoe, E. J., Streeter, K. B., Schwam, H., Michelson, S. R., Patchett, A. A., Taub, D.

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Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides von Graham, Samuel L, Hoffman, Jacob M, Gautheron, Pierre, Michelson, Stuart R, Scholz, Thomas H, Schwam, Harvey, Shepard, Kenneth L, Smith, Anthony M, Smith, Robert L

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Development of Orally Active Oxytocin Antagonists:  Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d... von Bell, Ian M, Erb, Jill M, Freidinger, Roger M, Gallicchio, Steven N, Guare, James P, Guidotti, Maribeth T, Halpin, Rita A, Hobbs, Doug W, Homnick, Carl F, Kuo, Michelle S, Lis, Edward V, Mathre, David J, Michelson, Stuart R, Pawluczyk, Joseph M, Pettibone, Douglas J, Reiss, Duane R, Vickers, Stanley, Williams, Peter D, Woyden, Carla J

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New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thioph... von Prugh, John D, Hartman, George D, Mallorga, Pierre J, McKeever, Brian M, Michelson, Stuart R, Murcko, Mark A, Schwam, Harvey, Smith, Robert L, Sondey, John M

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Development of orally active oxytocin antagonists : Studies on 1-(1-{4-[1-(2-methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2-methoxybenzo yl}piperidin-4-yl)-1,4-dihydrobenz[d... von BELL, I. M, ERB, J. M, LIS, E. V, MATHRE, D. J, MICHELSON, S. R, PAWLUCZYK, J. M, PETTIBONE, D. J, REISS, D. R, VICKERS, S, WILLIAMS, P. D, WOYDEN, C. J, FREIDINGER, R. M, GALLICCHIO, S. N, GUARE, J. P, GUIDOTTI, M. T, HALPIN, R. A, HOBBS, D. W, HOMNICK, C. F, KUO, M. S

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Topically active carbonic anhydrase inhibitors. 4. [(Hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides von Shepard, Kenneth L, Graham, Samuel L, Hudcosky, Ronald J, Michelson, Stuart R, Scholz, Thomas H, Schwam, Harvey, Smith, Anthony M, Sondey, John M, Strohmaier, Kim M

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Topically active carbonic anhydrase inhibitors. 1. O-Acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide von Woltersdorf, O. W., Schwam, H., Bicking, J. B., Brown, S. L., DeSolms, S. J., Fishman, D. R., Graham, S. L., Gautheron, P. D., Hoffman, J. M.

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Topically active carbonic anhydrase inhibitors. IV: [(hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides von SHEPARD, K. L, GRAHAM, S. L, SUGRUE, M. F, HUDCOSKY, R. J, MICHELSON, S. R, SCHOLZ, T. H, SCHWAM, H, SMITH, A. M, SONDEY, J. M, STROHMAIER, K. M, SMITH, R. L

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New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors : 5-substituted thieno [2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]tiop... von PRUGH, J. D, HARTMAN, G. D, SUGRUE, M. F, MALLORGA, P. J, MCKEEVER, B. M, MICHELSON, S. R, MURCKO, M. A, SCHWAM, H, SMITH, R. L, SONDEY, J. M, SPRINGER, J. P

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Topically active carbonic anhydrase inhibitors. III: Benzofuran- and indole-2-sulfonamides von GRAHAM, S. L, HOFFMAN, J. M, SUGRUE, M. F, GAUTHERON, P, MICHELSON, S. R, SCHOLZ, T. H, SCHWAM, H, SHEPARD, K. L, SMITH, A. M, SMITH, R. L, SONDEY, J. M

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Topically active carbonic anhydrase inhibitors. II: Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity von GRAHAM, S. L, SHEPARD, K. L, LYLE, P. A, MICHELSON, S. R, PONTICELLO, G. S, ROBB, C. M, SCHWAM, H, SMITH, A. M, SMITH, R. L, SONDEY, J. M, STROHMAIER, K. M, SUGRUE, M. F, ANDERSON, P. S, VARGA, S. L, BALDWIN, J. J, BEST, D. B, CHRISTY, M. E, FREEDMAN, M. B, GAUTHERON, P, HABECKER, C. N, HOFFMAN, J. M

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Topically active carbonic anhydrase inhibitors. I: O-Acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide von WOLTERSDORF, O. W. JR, SCHWAM, H, LEE, W. S, MICHELSON, S. R, ROBB, C. M, SHARE, N. N, SHEPARD, K. L, SMITH, A. M, SMITH, R. L, SMITH, J. M, SONDEY, J. M, STROHMAIER, K. M, BICKING, J. B, SUGRUE, M. F, VIADER, M. P, BROWN, S. L, DESOLMS, S. J, FISHMAN, D. R, GRAHAM, S. L, GAUTHERON, P. D, HOFFMAN, J. M, LARSON, R. D

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