Molecular Pathways: Targeting Mechanisms of Asbestos and Erionite Carcinogenesis in Mesothelioma von CARBONS, Michele, HAINING YANG

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HMGB1 as a therapeutic target in disease von Xue, Jiaming, Suarez, Joelle S., Minaai, Michael, Li, Shuangjing, Gaudino, Giovanni, Pass, Harvey I., Carbone, Michele, Yang, Haining

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Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma von Guo, Guangwu, Chmielecki, Juliann, Goparaju, Chandra, Heguy, Adriana, Dolgalev, Igor, Carbone, Michele, Seepo, Sara, Meyerson, Matthew, Pass, Harvey I

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Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer von Carbone, Michele, Harbour, J. William, Brugarolas, James, Bononi, Angela, Pagano, Ian, Dey, Anwesha, Krausz, Thomas, Pass, Harvey, Yang, Haining, Gaudino, Giovanni

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Mesothelioma: Scientific clues for prevention, diagnosis, and therapy von Carbone, Michele, Adusumilli, Prasad S., Alexander, H. Richard, Baas, Paul, Bardelli, Fabrizio, Bononi, Angela, Bueno, Raphael, Felley‐Bosco, Emanuela, Galateau‐Salle, Francoise, Jablons, David, Mansfield, Aaron S., Minaai, Michael, Perrot, Marc, Pesavento, Patricia, Rusch, Valerie, Severson, David T., Taioli, Emanuela, Tsao, Anne, Woodard, Gavitt, Yang, Haining, Zauderer, Marjorie G., Pass, Harvey I.

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BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation von Bononi, Angela, Giorgi, Carlotta, Patergnani, Simone, Larson, David, Verbruggen, Kaitlyn, Tanji, Mika, Pellegrini, Laura, Signorato, Valentina, Olivetto, Federica, Pastorino, Sandra, Nasu, Masaki, Napolitano, Andrea, Gaudino, Giovanni, Morris, Paul, Sakamoto, Greg, Ferris, Laura K., Danese, Alberto, Raimondi, Andrea, Tacchetti, Carlo, Kuchay, Shafi, Pass, Harvey I., Affar, El Bachir, Yang, Haining, Pinton, Paolo, Carbone, Michele

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Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burden of mesothelioma von Carbone, Michele, Minaai, Michael, Takinishi, Yasutaka, Pagano, Ian, Yang, Haining

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Germline BAP1 mutations predispose to malignant mesothelioma von Testa, Joseph R, Carbone, Michele, Cheung, Mitchell, Pei, Jianming, Below, Jennifer E, Tan, Yinfei, Sementino, Eleonora, Cox, Nancy J, Dogan, A Umran, Pass, Harvey I, Trusa, Sandra, Hesdorffer, Mary, Nasu, Masaki, Powers, Amy, Rivera, Zeyana, Comertpay, Sabahattin, Tanji, Mika, Gaudino, Giovanni, Yang, Haining

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High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma von Nasu, Masaki, Emi, Mitsuru, Pastorino, Sandra, Tanji, Mika, Powers, Amy, Luk, Hugh, Baumann, Francine, Zhang, Yu-an, Gazdar, Adi, Kanodia, Shreya, Tiirikainen, Maarit, Flores, Erin, Gaudino, Giovanni, Becich, Michael J., Pass, Harvey I., Yang, Haining, Carbone, Michele

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Malignant mesothelioma: Facts, Myths, and Hypotheses von Carbone, Michele, Ly, Bevan H., Dodson, Ronald F., Pagano, Ian, Morris, Paul T., Dogan, Umran A., Gazdar, Adi F., Pass, Harvey I., Yang, Haining

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Germline BAP1 mutations induce a Warburg effect von Bononi, Angela, Yang, Haining, Giorgi, Carlotta, Patergnani, Simone, Pellegrini, Laura, Su, Mingming, Xie, Guoxiang, Signorato, Valentina, Pastorino, Sandra, Morris, Paul, Sakamoto, Greg, Kuchay, Shafi, Gaudino, Giovanni, Pass, Harvey I, Napolitano, Andrea, Pinton, Paolo, Jia, Wei, Carbone, Michele

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HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients von Napolitano, Andrea, Antoine, Daniel J, Pellegrini, Laura, Baumann, Francine, Pagano, Ian, Pastorino, Sandra, Goparaju, Chandra M, Prokrym, Kirill, Canino, Claudia, Pass, Harvey I, Carbone, Michele, Yang, Haining

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Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy von Xue, Jiaming, Patergnani, Simone, Giorgi, Carlotta, Suarez, Joelle, Goto, Keisuke, Bononi, Angela, Tanji, Mika, Novelli, Flavia, Pastorino, Sandra, Xu, Ronghui, Caroccia, Natascia, Dogan, A. Umran, Pass, Harvey I., Tognon, Mauro, Pinton, Paolo, Gaudino, Giovanni, Mak, Tak W., Carbone, Michele, Yang, Haining

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Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma von JUBE, Sandro, RIVERA, Zeyana S, BIANCHI, Marco E, POWERS, Amy, WANG, Ena, PAGANO, Ian, PASS, Harvey I, GAUDINO, Giovanni, CARBONE, Michele, HAINING YANG

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Mesothelioma Biomarkers: A Review Highlighting Contributions from the Early Detection Research Network von Pass, Harvey I., Alimi, Marjan, Carbone, Michele, Yang, Haining, Goparaju, Chandra M.

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Fibulin-3 as a Blood and Effusion Biomarker for Pleural Mesothelioma von Pass, Harvey I, Levin, Stephen M, Harbut, Michael R, Melamed, Jonathan, Chiriboga, Luis, Donington, Jessica, Huflejt, Margaret, Carbone, Michele, Chia, David, Goodglick, Lee, Goodman, Gary E, Thornquist, Mark D, Liu, Geoffrey, de Perrot, Marc, Tsao, Ming-Sound, Goparaju, Chandra

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Scientific Advances and New Frontiers in Mesothelioma Therapeutics von Mutti, Luciano, Peikert, Tobias, Robinson, Bruce W.S., Scherpereel, Arnaud, Tsao, Anne S., de Perrot, Marc, Woodard, Gavitt A., Jablons, David M., Wiens, Jacinta, Hirsch, Fred R., Yang, Haining, Carbone, Michele, Thomas, Anish, Hassan, Raffit

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Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation von Yang, Haining, Rivera, Zeyana, Jube, Sandro, Nasu, Masaki, Bertino, Pietro, Goparaju, Chandra, Franzoso, Guido, Lotze, Michael T., Krausz, Thomas, Pass, Harvey I., Bianchi, Marco E., Carbone, Michele, Rowley, Janet D.

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The Presence of Asbestos in the Natural Environment is Likely Related to Mesothelioma in Young Individuals and Women from Southern Nevada von Baumann, Francine, Buck, Brenda J., Metcalf, Rodney V., McLaurin, Brett T., Merkler, Douglas J., Carbone, Michele

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The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer von Daou, Salima, Hammond-Martel, Ian, Mashtalir, Nazar, Barbour, Haithem, Gagnon, Jessica, Iannantuono, NicholasV.G., Nkwe, Nadine Sen, Motorina, Alena, Pak, Helen, Yu, Helen, Wurtele, Hugo, Milot, Eric, Mallette, Frédérick A., Carbone, Michele, Affar, El Bachir

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