SARS-CoV-2-specific CD4 + and CD8 + T cell responses can originate from cross-reactive CMV-specific T cells von Pothast, Cilia R, Dijkland, Romy C, Thaler, Melissa, Hagedoorn, Renate S, Kester, Michel G D, Wouters, Anne K, Hiemstra, Pieter S, van Hemert, Martijn J, Gras, Stephanie, Falkenburg, J H Frederik, Heemskerk, Mirjam H M

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PD-1/PD-L1 Interactions Contribute to Functional T-Cell Impairment in Patients Who Relapse with Cancer After Allogeneic Stem Cell Transplantation von NORDE, Wieger J, MAAS, Frans, VAN DER VOORT, Robbert, DOLSTRA, Harry, HOBO, Willemijn, KORMAN, Alan, QUIGLEY, Michael, KESTER, Michel G. D, HEBEDA, Konnie, FALKENBURG, J. H. Frederik, SCHAAP, Nicolaas, DE WITTE, Theo M

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PRAME-Specific Allo-HLA―Restricted T Cells with Potent Antitumor Reactivity Useful for Therapeutic T-Cell Receptor Gene Transfer von AMIR, Avital L, VAN DER STEEN, Dirk M, JEDEMA, Inge, GRIFFIOEN, Marieke, VAN VEELEN, Peter A, FALKENBURG, J. H. Frederik, HEEMSKERK, Mirjam H. M, VAN LOENEN, Marleen M, HAGEDOORN, Renate S, DE BOER, Renate, KESTER, Michel D. G, DE RU, Arnoud H, LUGTHART, Gert-Jan, VAN KOOTEN, Cees, HIEMSTRA, Pieter S

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Autoreactive CD8 T Cells Associated with β Cell Destruction in Type 1 Diabetes von Gabrielle G. M. Pinkse, Odette H. M. Tysma, Cees A. M. Bergen, Michel G. D. Kester, Ossendorp, Ferry, van Veelen, Peter A., Bart Keymeulen, Pipeleers, Danny, Drijfhout, Jan W., Roep, Bart O., van Rood, Johannes

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High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning von VAN BERGEN, Cornelis A. M, RUTTEN, Caroline E, GRIFFIOEN, Marieke, VAN DER MEIJDEN, Edith D, VAN LUXEMBURG-HEIJS, Simone A. P, LURVINK, Ellie G. A, HOUWING-DUISTERMAAT, Jeanine J, KESTER, Michel G. D, MULDER, Arend, WILLEMZE, Roel, FALKENBURG, J. H. Frederik

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High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations von Hombrink, Pleun, Hadrup, Sine R, Bakker, Arne, Kester, Michel G D, Falkenburg, J H Frederik, von dem Borne, Peter A, Schumacher, Ton N M, Heemskerk, Mirjam H M

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Allo-HLA reactivity of virus-specific memory T cells is common von Amir, Avital L, D'Orsogna, Lloyd J.A, Roelen, Dave L, van Loenen, Marleen M, Hagedoorn, Renate S, de Boer, Renate, van der Hoorn, Menno A.W.G, Kester, Michel G.D, Doxiadis, Ilias I.N, Falkenburg, J. H. Frederik, Claas, Frans H.J, Heemskerk, Mirjam H.M

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Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection von ZANDVLIET, Maarten L, FREDERIK FALKENBURG, J. H, GUCHELAAR, Henk-Jan, SCHILHAM, Marco W, MEIJ, Pauline, VAN LIEMPT, Ellis, VELTROP-DUITS, Louise A, LANKESTER, Arjan C, KALPOE, Jayant S, KESTER, Michel G. D, VAN DER STEEN, Dirk M, VAN TOL, Maarten J, WILLEMZE, Roel

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Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+ T cell and NK cell responses in vitro and in vivo von van Eck van der Sluijs, Jesper, van Ens, Diede, Brummelman, Jolanda, Heister, Daan, Sareen, Aastha, Truijen, Lisa, van Ingen Schenau, Dorette S., Heemskerk, Mirjam H. M., Griffioen, Marieke, Kester, Michel G. D., Schaap, Nicolaas P. M., Jansen, Joop H., van der Waart, Anniek B., Dolstra, Harry, Hobo, Willemijn

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Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers von Unger, Wendy W, Velthuis, Jurjen, Abreu, Joana R.F, Laban, Sandra, Quinten, Edwin, Kester, Michel G.D, Reker-Hadrup, Sine, Bakker, Arnold H, Duinkerken, Gaby, Mulder, Arend, Franken, Kees L.M.C, Hilbrands, Robert, Keymeulen, Bart, Peakman, Mark, Ossendorp, Ferry, Drijfhout, Jan Wouter, Schumacher, Ton N, Roep, Bart O

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Antibody-mediated delivery of viral epitopes to redirect EBV-specific CD8+ T-cell immunity towards cancer cells von van der Wulp, Willemijn, Remst, Dennis F. G., Kester, Michel G. D., Hagedoorn, Renate S., Parren, Paul W. H. I., van Kasteren, Sander I., Schuurman, Janine, Hoeben, Rob C., Ressing, Maaike E., Bleijlevens, Boris, Heemskerk, Mirjam H. M.

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Clinically applicable CD34+-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses von van Eck van der Sluijs, Jesper, van Ens, Diede, Thordardottir, Soley, Vodegel, Denise, Hermens, Inge, van der Waart, Anniek B., Falkenburg, J. H. Frederik, Kester, Michel G. D., de Rink, Iris, Heemskerk, Mirjam H. M., Borst, Jannie, Schaap, Nicolaas P. M., Jansen, Joop H., Xiao, Yanling, Dolstra, Harry, Hobo, Willemijn

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Accurate prediction of HLA class II antigen presentation across all loci using tailored data acquisition and refined machine learning von Nilsson, Jonas B, Kaabinejadian, Saghar, Yari, Hooman, Kester, Michel G D, van Balen, Peter, Hildebrand, William H, Nielsen, Morten

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Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy von Griffioen, Marieke, van Egmond, Esther H.M, Kester, Michel G.D, Willemze, Roel, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M

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The Human Leukocyte Antigen–presented Ligandome of B Lymphocytes von Hassan, Chopie, Kester, Michel G.D., de Ru, Arnoud H., Hombrink, Pleun, Drijfhout, Jan Wouter, Nijveen, Harm, Leunissen, Jack A.M., Heemskerk, Mirjam H.M., Falkenburg, J.H. Frederik, van Veelen, Peter A.

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Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy von Mousset, Charlotte M., Hobo, Willemijn, Ji, Yun, Fredrix, Hanny, De Giorgi, Valeria, Allison, Robert D., Kester, Michel G. D., Falkenburg, J. H. Frederik, Schaap, Nicolaas P. M., Jansen, Joop H., Gattinoni, Luca, Dolstra, Harry, van der Waart, Anniek B.

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Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity von Laghmouchi, Aicha, Kester, Michel G D, Hoogstraten, Conny, Hageman, Lois, de Klerk, Wendy, Huisman, Wesley, Koster, Eva A S, de Ru, Arnoud H, van Balen, Peter, Klobuch, Sebastian, van Veelen, Peter A, Falkenburg, J H Frederik, Jedema, Inge

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Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain von Meeuwsen, Miranda H, Wouters, Anne K, Wachsmann, Tassilo L A, Hagedoorn, Renate S, Kester, Michel G D, Remst, Dennis F G, van der Steen, Dirk M, de Ru, Arnoud H, van Hees, Els P, Kremer, Martijn, Griffioen, Marieke, van Veelen, Peter A, Falkenburg, J H Frederik, Heemskerk, Mirjam H M

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Promiscuous binding of invariant chain-derived CLIP peptide to distinct HLA-I molecules revealed in leukemic cells von van Luijn, Marvin M, van de Loosdrecht, Arjan A, Lampen, Margit H, van Veelen, Peter A, Zevenbergen, Adri, Kester, Michel G D, de Ru, Arnoud H, Ossenkoppele, Gert J, van Hall, Thorbald, van Ham, S Marieke

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Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice von Unger, Wendy W J, Pearson, Todd, Abreu, Joana R F, Laban, Sandra, van der Slik, Arno R, der Kracht, Sacha Mulder-van, Kester, Michel G D, Serreze, Dave V, Shultz, Leonard D, Griffioen, Marieke, Drijfhout, Jan Wouter, Greiner, Dale L, Roep, Bart O

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