Molecular mechanisms of protein aggregation from global fitting of kinetic models von Meisl, Georg, Kirkegaard, Julius B, Arosio, Paolo, Michaels, Thomas C T, Vendruscolo, Michele, Dobson, Christopher M, Linse, Sara, Knowles, Tuomas P J

Volltext

Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation von Michaels, Thomas C.T, Šari, An ela, Habchi, Johnny, Chia, Sean, Meisl, Georg, Vendruscolo, Michele, Dobson, Christopher M, Knowles, Tuomas P.J

Volltext

Secondary nucleation in amyloid formation von Törnquist, Mattias, Michaels, Thomas C. T, Sanagavarapu, Kalyani, Yang, Xiaoting, Meisl, Georg, Cohen, Samuel I. A, Knowles, Tuomas P. J, Linse, Sara

Volltext

Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide von Michaels, Thomas C. T., Šarić, Andela, Curk, Samo, Bernfur, Katja, Arosio, Paolo, Meisl, Georg, Dear, Alexander J., Cohen, Samuel I. A., Dobson, Christopher M., Vendruscolo, Michele, Linse, Sara, Knowles, Tuomas P. J.

Volltext

Identification of on- and off-pathway oligomers in amyloid fibril formation von Dear, Alexander J, Meisl, Georg, Šari, An ela, Michaels, Thomas C. T, Kjaergaard, Magnus, Linse, Sara, Knowles, Tuomas P. J

Volltext

Kinetic diversity of amyloid oligomers von Dear, Alexander J., Michaels, Thomas C. T., Meisl, Georg, Klenerman, David, Wu, Si, Perrett, Sarah, Linse, Sara, Dobson, Christopher M., Knowles, Tuomas P. J.

Volltext

Mechanical basis for fibrillar bundle morphology von Michaels, Thomas C. T, Memet, Edvin, Mahadevan, L

Volltext

A solid beta-sheet structure is formed at the surface of FUS droplets during aging von Emmanouilidis, Leonidas, Bartalucci, Ettore, Kan, Yelena, Ijavi, Mahdiye, Pérez, Maria Escura, Afanasyev, Pavel, Boehringer, Daniel, Zehnder, Johannes, Parekh, Sapun H., Bonn, Mischa, Michaels, Thomas C. T., Wiegand, Thomas, Allain, Frédéric H.-T.

Volltext

Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces von Levin, Aviad, Michaels, Thomas C. T, Mason, Thomas O, Müller, Thomas, Adler-Abramovich, Lihi, Mahadevan, Lakshminarayanan, Cates, Michael E, Gazit, Ehud, Knowles, Tuomas P. J

Volltext

Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces von Song, Yang, Shimanovich, Ulyana, Michaels, Thomas C. T., Ma, Qingming, Li, Jingmei, Knowles, Tuomas P. J., Shum, Ho Cheung

Volltext

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation von Galvagnion, Céline, Buell, Alexander K, Meisl, Georg, Michaels, Thomas C T, Vendruscolo, Michele, Knowles, Tuomas P J, Dobson, Christopher M

Volltext

Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils von Song, Yang, Michaels, Thomas C. T., Ma, Qingming, Liu, Zhou, Yuan, Hao, Takayama, Shuichi, Knowles, Tuomas P. J., Shum, Ho Cheung

Volltext

Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation von Arosio, Paolo, Michaels, Thomas C. T., Linse, Sara, Månsson, Cecilia, Emanuelsson, Cecilia, Presto, Jenny, Johansson, Jan, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.

Volltext

Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes von Habchi, Johnny, Chia, Sean, Galvagnion, Céline, Michaels, Thomas C. T., Bellaiche, Mathias M. J., Ruggeri, Francesco Simone, Sanguanini, Michele, Idini, Ilaria, Kumita, Janet R., Sparr, Emma, Linse, Sara, Dobson, Christopher M., Knowles, Tuomas P. J., Vendruscolo, Michele

Volltext

Physical determinants of the self-replication of protein fibrils von Šarić, Anđela, Buell, Alexander K., Meisl, Georg, Michaels, Thomas C. T., Dobson, Christopher M., Linse, Sara, Knowles, Tuomas P. J., Frenkel, Daan

Volltext

Analytical Solution to the Flory–Huggins Model von Qian, Daoyuan, Michaels, Thomas C. T., Knowles, Tuomas P. J.

Volltext

Scaling analysis reveals the mechanism and rates of prion replication in vivo von Meisl, Georg, Kurt, Timothy, Condado-Morales, Itzel, Bett, Cyrus, Sorce, Silvia, Nuvolone, Mario, Michaels, Thomas C. T., Heinzer, Daniel, Avar, Merve, Cohen, Samuel I. A., Hornemann, Simone, Aguzzi, Adriano, Dobson, Christopher M., Sigurdson, Christina J., Knowles, Tuomas P. J.

Volltext

Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation von Šarić, Anđela, Michaels, Thomas C. T., Zaccone, Alessio, Knowles, Tuomas P. J., Frenkel, Daan

Volltext

Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform von Mason, Thomas O, Michaels, Thomas C. T, Levin, Aviad, Gazit, Ehud, Dobson, Christopher M, Buell, Alexander K, Knowles, Tuomas P. J

Volltext

Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly von Adler-Abramovich, Lihi, Marco, Pini, Arnon, Zohar A, Creasey, Rhiannon C. G, Michaels, Thomas C. T, Levin, Aviad, Scurr, David J, Roberts, Clive J, Knowles, Tuomas P. J, Tendler, Saul J. B, Gazit, Ehud

Volltext