TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis von Ganz, Tomas, Nemeth, Elizabeta, Rivella, Stefano, Goldberg, Paul, Dibble, Andrew R., McCaleb, Michael L., Guo, Shuling, Monia, Brett P., Barrett, Terrance D.

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Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice von Yu, Xing Xian, Watts, Lynnetta M, Manchem, Vara Prasad, Chakravarty, Kaushik, Monia, Brett P, McCaleb, Michael L, Bhanot, Sanjay

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IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal von Weng, Shih-Yen, Wang, Xiaoyu, Vijayan, Santosh, Tang, Yilang, Kim, Yong Ook, Padberg, Kornelius, Regen, Tommy, Molokanova, Olena, Chen, Tao, Bopp, Tobias, Schild, Hansjörg, Brombacher, Frank, Crosby, Jeff R., McCaleb, Michael L., Waisman, Ari, Bockamp, Ernesto, Schuppan, Detlef

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Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration von Murray, Susan F, Jazayeri, Ali, Matthes, Michael T, Yasumura, Douglas, Yang, Haidong, Peralta, Raechel, Watt, Andy, Freier, Sue, Hung, Gene, Adamson, Peter S, Guo, Shuling, Monia, Brett P, LaVail, Matthew M, McCaleb, Michael L

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New Potent Antihyperglycemic Agents in db/db Mice:  Synthesis and Structure−Activity Relationship Studies of (4-Substituted benzyl)(trifluoromethyl)pyrazoles and -pyrazolones von Kees, Kenneth L, Fitzgerald, John J, Steiner, Kurt E, Mattes, James F, Mihan, Brenda, Tosi, Theresa, Mondoro, Diane, McCaleb, Michael L

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In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides von Billioud, Gaetan, Kruse, Robert L, Carrillo, Melissa, Whitten-Bauer, Christina, Gao, Dacao, Kim, Aneeza, Chen, Leon, McCaleb, Michael L, Crosby, Jeffrey R, Hamatake, Robert, Hong, Zhi, Garaigorta, Urtzi, Swayze, Eric, Bissig, Karl-Dimiter, Wieland, Stefan

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Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice von Guo, Shuling, Booten, Sheri L, Aghajan, Mariam, Hung, Gene, Zhao, Chenguang, Blomenkamp, Keith, Gattis, Danielle, Watt, Andrew, Freier, Susan M, Teckman, Jeffery H, McCaleb, Michael L, Monia, Brett P

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Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide von Grossman, Tamar R, Carrer, Michele, Shen, Lijiang, Johnson, Robert B, Hettrick, Lisa A, Henry, Scott P, Monia, Brett P, McCaleb, Michael L

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Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice von Grossman, Tamar R, Hettrick, Lisa A, Johnson, Robert B, Hung, Gene, Peralta, Raechel, Watt, Andrew, Henry, Scott P, Adamson, Peter, Monia, Brett P, McCaleb, Michael L

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593 Antisense Oligonucleotide Reduction of Mutant Alpha-1 Antitrypsin Protein for the Treatment of Alpha-1 Antitrypsin Liver Disease von Guo, Shuling, Freier, Susan M, Booten, Sheri L, Watt, Andrew, Peralta, Raechel Q, Blomenkamp, Keith S, Teckman, Jeffrey, Monia, Brett P, McCaleb, Michael L

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Identification of a Novel Hypothalamic Neuropeptide Y Receptor Associated with Feeding Behavior von Yinghe Hu, Brian T. Bloomquist, Linda J. Cornfield, Lynn B. DeCarr, Jaime R. Flores-Riveros, Lizbeth Friedman, Peiling Jiang, Lore Lewis-Higgins, Yola Sadlowski, Jean Schaefer, Nelson Velazquez, Michael L. McCaleb

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Molecular Characterization of a Second Mouse Pancreatic Polypeptide Receptor and Its Inactivated Human Homologue von Gregor, Paul, Feng, Yun, DeCarr, Lynn B., Cornfield, Linda J., McCaleb, Michael L.

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Clinical Trial Design for Alpha-1 Antitrypsin Deficiency: A Model for Rare Diseases von Wanner, Adam, Groft, Stephen C, Teagarden, J Russell, Krischer, Jeffrey, Davis, Barry R, Coffey, Christopher S, Hickam, David H, Teckman, Jeffrey, Nelson, David R, McCaleb, Michael L, Loomba, Rohit, Strange, Charlie, Sandhaus, Robert A, Brantly, Mark, Edelman, Jonathan M, Farrugia, Albert

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Studies on New Acidic Azoles as Glucose-Lowering Agents in Obese, Diabetic db/db Mice von Kees, Kenneth L, Caggiano, Thomas J, Steiner, Kurt E, Fitzgerald, John J, Kates, Michael J, Christos, Thomas E, Kulishoff, John M, Moore, Robin D, McCaleb, Michael L

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Cloning and characterization of a novel receptor to pancreatic polypeptide, a member of the neuropeptide Y receptor family von Gregor, Paul, Millham, Michele L., Feng, Yun, DeCarr, Lynn B., McCaleb, Michael L., Cornfield, Linda J.

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Antihyperglycemic activity of novel substituted 3H-1,2,3,5-oxathiadiazole 2-oxides von Ellingboe, John W, Alessi, Thomas R, Dolak, Terence M, Nguyen, Thomas T, Tomer, John D, Guzzo, Frieda, Bagli, Jehan F, McCaleb, Michael L

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Synthesis and antihyperglycemic activity of novel 5-(naphthalenylsulfonyl)-2,4-thiazolidinediones von Zask, Arie, Jirkovsky, Ivo, Nowicki, James W, McCaleb, Michael L

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Metabolic abnormalities of the hyperglycemic obese Zucker rat von McCaleb, Michael L., Sredy, Janet

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Degenerated intramural pericytes ('ghost cells') in the retinal capillaries of diabetic rats von Robinson, W. Gerald, McCaleb, Michael L., Feld, Leonard G., Michaelis, Otho E., And, Nora Laver, Mercandetti, Michael

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Perfluorocarbon-based antidiabetic agents von Kees, Kenneth L, Smith, Ted M, McCaleb, Michael L, Prozialeck, Dorothy H, Cheeseman, Robert S, Christos, Thomas E, Patt, William C, Steiner, Kurt E

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