Rheumatoid Arthritis Pathogenesis, Prediction, and Prevention: An Emerging Paradigm Shift von Deane, Kevin D., Holers, V. Michael

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Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo von Chen, Fangfang, Wang, Guankui, Griffin, James I., Brenneman, Barbara, Banda, Nirmal K., Holers, V. Michael, Backos, Donald S., Wu, LinPing, Moghimi, Seyed Moein, Simberg, Dmitri

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Complement in the Initiation and Evolution of Rheumatoid Arthritis von Holers, V Michael, Banda, Nirmal K

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Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction von Holers, V. Michael, Demoruelle, M. Kristen, Kuhn, Kristine A., Buckner, Jane H., Robinson, William H., Okamoto, Yuko, Norris, Jill M., Deane, Kevin D.

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Genetic and environmental risk factors for rheumatoid arthritis von Deane, Kevin D., Demoruelle, M. Kristen, Kelmenson, Lindsay B., Kuhn, Kristine A., Norris, Jill M., Holers, V. Michael

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Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis von Sokolove, Jeremy, Bromberg, Reuven, Deane, Kevin D, Lahey, Lauren J, Derber, Lezlie A, Chandra, Piyanka E, Edison, Jess D, Gilliland, William R, Tibshirani, Robert J, Norris, Jill M, Holers, V Michael, Robinson, William H

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Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry von Zhang, Fan, Wei, Kevin, Slowikowski, Kamil, Fonseka, Chamith Y., Rao, Deepak A., Kelly, Stephen, Goodman, Susan M., Tabechian, Darren, Hughes, Laura B., Salomon-Escoto, Karen, Watts, Gerald F. M., Jonsson, A. Helena, Rangel-Moreno, Javier, Meednu, Nida, Rozo, Cristina, Apruzzese, William, Eisenhaure, Thomas M., Lieb, David J., Boyle, David L., Mandelin, Arthur M., Boyce, Brendan F., DiCarlo, Edward, Gravallese, Ellen M., Gregersen, Peter K., Moreland, Larry, Firestein, Gary S., Hacohen, Nir, Nusbaum, Chad, Lederer, James A., Perlman, Harris, Pitzalis, Costantino, Filer, Andrew, Holers, V. Michael, Bykerk, Vivian P., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya

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Biological classification of childhood arthritis: roadmap to a molecular nomenclature von Nigrovic, Peter A., Colbert, Robert A., Holers, V. Michael, Ozen, Seza, Ruperto, Nicolino, Thompson, Susan D., Wedderburn, Lucy R., Yeung, Rae S. M., Martini, Alberto

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Complement and Its Receptors: New Insights into Human Disease von Holers, V. Michael

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Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis von Mikuls, Ted R., Thiele, Geoffrey M., Deane, Kevin D., Payne, Jeffrey B., O'Dell, James R., Yu, Fang, Sayles, Harlan, Weisman, Michael H., Gregersen, Peter K., Buckner, Jane H., Keating, Richard M., Derber, Lezlie A., Robinson, William H., Holers, V. Michael, Norris, Jill M.

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The Central Role of the Alternative Complement Pathway in Human Disease von Thurman, Joshua M, Holers, V. Michael

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Complement: The Road Less Traveled von Kemper, Claudia, Ferreira, Viviana P, Paz, Jeanne T, Holers, V Michael, Lionakis, Michail S, Alexander, Jessy J

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Biomarkers of terminal complement activation confirm the diagnosis of aHUS and differentiate aHUS from TTP von Cataland, Spero R., Holers, V. Michael, Geyer, Susan, Yang, Shangbin, Wu, Haifeng M.

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C3 glomerulopathy: consensus report von Pickering, Matthew C., D'Agati, Vivette D., Nester, Carla M., Smith, Richard J., Haas, Mark, Appel, Gerald B., Alpers, Charles E., Bajema, Ingeborg M., Bedrosian, Camille, Braun, Michael, Doyle, Mittie, Fakhouri, Fadi, Fervenza, Fernando C., Fogo, Agnes B., Frémeaux-Bacchi, Véronique, Gale, Daniel P., Goicoechea de Jorge, Elena, Griffin, Gene, Harris, Claire L., Michael Holers, V., Johnson, Sally, Lavin, Peter J., Medjeral-Thomas, Nicholas, Paul Morgan, B., Nast, Cynthia C., Noel, Laure-Hélène, Keith Peters, D., Rodríguez de Córdoba, Santiago, Servais, Aude, Sethi, Sanjeev, Song, Wen-Chao, Tamburini, Paul, Thurman, Joshua M., Zavros, Michael, Terence Cook, H.

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Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension von Frid, Maria G, McKeon, B Alexandre, Thurman, Joshua M, Maron, Bradley A, Li, Min, Zhang, Hui, Kumar, Sushil, Sullivan, Timothy, Laskowsky, Jennifer, Fini, Mehdi A, Hu, Samantha, Tuder, Rubin M, Gandjeva, Aneta, Wilkins, Martin R, Rhodes, Christopher J, Ghataorhe, Pavandeep, Leopold, Jane A, Wang, Rui-Sheng, Holers, V Michael, Stenmark, Kurt R

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Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction von Girardi, Guillermina, Yarilin, Dmitry, Thurman, Joshua M, Holers, V Michael, Salmon, Jane E

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Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway–mediated diseases von Fridkis-Hareli, Masha, Storek, Michael, Mazsaroff, Istvan, Risitano, Antonio M., Lundberg, Ante S., Horvath, Christopher J., Holers, V. Michael

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Identification of a central role for complement in osteoarthritis von Wang, Qian, Rozelle, Andrew L, Lepus, Christin M, Scanzello, Carla R, Song, Jason J, Larsen, D Meegan, Crish, James F, Bebek, Gurkan, Ritter, Susan Y, Lindstrom, Tamsin M, Hwang, Inyong, Wong, Heidi H, Punzi, Leonardo, Encarnacion, Angelo, Shamloo, Mehrdad, Goodman, Stuart B, Wyss-Coray, Tony, Goldring, Steven R, Banda, Nirmal K, Thurman, Joshua M, Gobezie, Reuben, Crow, Mary K, Holers, V Michael, Lee, David M, Robinson, William H

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In Memoriam: William Phelps Arend, MD, 1937–2020 von Michael Holers, V., Firestein, Gary S., Deane, Kevin D.

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Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis von Hernandez, Giovanny, Mills, Taylor S, Rabe, Jennifer L, Chavez, James S, Kuldanek, Susan, Kirkpatrick, Gregory, Noetzli, Leila, Jubair, Widian K, Zanche, Michelle, Myers, Jason R, Stevens, Brett M, Fleenor, Courtney J, Adane, Biniam, Dinarello, Charles A, Ashton, John, Jordan, Craig T, Di Paola, Jorge, Hagman, James R, Holers, V Michael, Kuhn, Kristine A, Pietras, Eric M

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