Exploring the specificity of the PI3K family inhibitor LY294002 von Gharbi, Severine I, Zvelebil, Marketa J, Shuttleworth, Stephen J, Hancox, Tim, Saghir, Nahid, Timms, John F, Waterfield, Michael D

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A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding von Jefferies, Harold B J, Cooke, Frank T, Jat, Parmjit, Boucheron, Christine, Koizumi, Tomonobu, Hayakawa, Masahiko, Kaizawa, Hiroyuki, Ohishi, Takahide, Workman, Paul, Waterfield, Michael D, Parker, Peter J

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CELLULAR FUNCTION OF PHOSPHOINOSITIDE 3-KINASES: Implications for Development, Immunity, Homeostasis, and Cancer von Katso, Roy, Okkenhaug, Klaus, Ahmadi, Khatereh, White, Sarah, Timms, John, Waterfield, Michael D

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SYNTHESIS AND FUNCTION OF 3-PHOSPHORYLATED INOSITOL LIPIDS von Vanhaesebroeck, Bart, Leevers, Sally J, Ahmadi, Khatereh, Timms, John, Katso, Roy, Driscoll, Paul C, Woscholski, Rudiger, Parker, Peter J, Waterfield, Michael D

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Evaluation of Two-dimensional Differential Gel Electrophoresis for Proteomic Expression Analysis of a Model Breast Cancer Cell System von Gharbi, Severine, Gaffney, Piers, Yang, Alice, Zvelebil, Marketa J, Cramer, Rainer, Waterfield, Michael D, Timms, John F

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Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras von Rodriguez-Viciana, Pablo, Warne, Patricia H, Khwaja, Asim, Marte, Barbara M, Pappin, Darryl, Das, Pamela, Waterfield, Michael D, Ridley, Anne, Downward, Julian

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Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis von Jovceva, Eleonora, Larsen, Martin R, Waterfield, Michael D, Baum, Buzz, Timms, John F

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Major Role of Epidermal Growth Factor Receptor and Src Kinases in Promoting Oxidative Stress-dependent Loss of Adhesion and Apoptosis in Epithelial Cells von Chan, Hong-Lin, Chou, Hsiu-Chuan, Duran, MaCarmen, Gruenewald, Jana, Waterfield, Michael D, Ridley, Anne, Timms, John F

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Cloning and Characterization of a G Protein-Activated Human Phosphoinositide-3 Kinase von Stoyanov, Borislav, Volinia, Stefano, Hanck, Theodor, Rubio, Ignacio, Loubtchenkov, Michael, Malek, Daria, Stoyanova, Stefka, Vanhaesebroeck, Bart, Dhand, Ritu, Nürnberg, Bernd, Gierschik, Peter, Seedorf, Klaus, Hsuan, J. Justin, Waterfield, Michael D., Wetzker, Reinhard

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Proteomic analysis of UVC irradiation-induced damage of plasma proteins: Serum amyloid P component as a major target of photolysis von Chan, Hong-Lin, Gaffney, Piers R., Waterfield, Michael D., Anderle, Heinz, Peter Matthiessen, H., Schwarz, Hans-Peter, Turecek, Peter L., Timms, John F.

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A selective PIKfyve inhibitor blocks PtdIns(3,5)P 2 production and disrupts endomembrane transport and retroviral budding von Jefferies, Harold B J, Cooke, Frank T, Jat, Parmjit, Boucheron, Christine, Koizumi, Tomonobu, Hayakawa, Masahiko, Kaizawa, Hiroyuki, Ohishi, Takahide, Workman, Paul, Waterfield, Michael D, Parker, Peter J

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Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation von Arcaro, Alexandre, Khanzada, Umme K., Vanhaesebroeck, Bart, Tetley, Teresa D., Waterfield, Michael D., Seckl, Michael J.

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Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice von Okkenhaug, Klaus, Bilancio, Antonio, Farjot, Géraldine, Priddle, Helen, Sancho, Sara, Peskett, Emma, Pearce, Wayne, Meek, Stephen E., Salpekar, Ashreena, Waterfield, Michael D., Andrew J. H. Smith, Vanhaesebroeck, Bart

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Signalling through phosphoinositide 3-kinases: the lipids take centre stage von Leevers, Sally J, Vanhaesebroeck, Bart, Waterfield, Michael D

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Synthesis and biological evaluation of pyrido[3′,2′:4,5]furo[3,2- d]pyrimidine derivatives as novel PI3 kinase p110α inhibitors von Hayakawa, Masahiko, Kaizawa, Hiroyuki, Moritomo, Hiroyuki, Koizumi, Tomonobu, Ohishi, Takahide, Yamano, Mayumi, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi, Raynaud, Florence I., Workman, Paul, Waterfield, Michael D., Parker, Peter

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Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2- a]pyridines as novel PI3 kinase p110α inhibitors von Hayakawa, Masahiko, Kawaguchi, Ken-ichi, Kaizawa, Hiroyuki, Koizumi, Tomonobu, Ohishi, Takahide, Yamano, Mayumi, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi, Raynaud, Florence I., Parker, Peter, Workman, Paul, Waterfield, Michael D.

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Targeted Expression of the Class II Phosphoinositide 3-Kinase in Drosophila melanogaster Reveals Lipid Kinase-Dependent Effects on Patterning and Interactions with Receptor Signali... von MacDougall, Lindsay K., Gagou, Mary Elizabeth, Leevers, Sally J., Hafen, Ernst, Waterfield, Michael D.

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Synthesis and biological evaluation of imidazo[1,2- a]pyridine derivatives as novel PI3 kinase p110α inhibitors von Hayakawa, Masahiko, Kaizawa, Hiroyuki, Kawaguchi, Ken-ichi, Ishikawa, Noriko, Koizumi, Tomonobu, Ohishi, Takahide, Yamano, Mayumi, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi, Raynaud, Florence I., Waterfield, Michael D., Parker, Peter, Workman, Paul

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Proteomic analysis of redox- and ErbB2-dependent changes in mammary luminal epithelial cells using cysteine- and lysine-labelling two-dimensional difference gel electrophoresis von Chan, Hong-Lin, Gharbi, Severine, Gaffney, Piers R., Cramer, Rainer, Waterfield, Michael D., Timms, John F.

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Identification of novel candidates for replicative senescence by functional proteomics von BENVENUTI, Silvia, CRAMER, Rainer, BRUCE, Jim, WATERFIELD, Michael D, JAT, Parmjit S

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