Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators von Liu, Nian, Lee, Cameron H., Swigut, Tomek, Grow, Edward, Gu, Bo, Bassik, Michael C., Wysocka, Joanna

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Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes von Hess, Gaelen T., Tycko, Josh, Yao, David, Bassik, Michael C.

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation von Gilbert, Luke A., Horlbeck, Max A., Adamson, Britt, Villalta, Jacqueline E., Chen, Yuwen, Whitehead, Evan H., Guimaraes, Carla, Panning, Barbara, Ploegh, Hidde L., Bassik, Michael C., Qi, Lei S., Kampmann, Martin, Weissman, Jonathan S.

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SLC19A1 Is an Importer of the Immunotransmitter cGAMP von Ritchie, Christopher, Cordova, Anthony F., Hess, Gaelen T., Bassik, Michael C., Li, Lingyin

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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis von Bersuker, Kirill, Hendricks, Joseph M., Li, Zhipeng, Magtanong, Leslie, Ford, Breanna, Tang, Peter H., Roberts, Melissa A., Tong, Bingqi, Maimone, Thomas J., Zoncu, Roberto, Bassik, Michael C., Nomura, Daniel K., Dixon, Scott J., Olzmann, James A.

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Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes von Morgens, David W, Deans, Richard M, Li, Amy, Bassik, Michael C

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A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility von Bassik, Michael C., Kampmann, Martin, Lebbink, Robert Jan, Wang, Shuyi, Hein, Marco Y., Poser, Ina, Weibezahn, Jimena, Horlbeck, Max A., Chen, Siyuan, Mann, Matthias, Hyman, Anthony A., LeProust, Emily M., McManus, Michael T., Weissman, Jonathan S.

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Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions von Han, Kyuho, Jeng, Edwin E, Hess, Gaelen T, Morgens, David W, Li, Amy, Bassik, Michael C

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Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells von Hess, Gaelen T, Frésard, Laure, Han, Kyuho, Lee, Cameron H, Li, Amy, Cimprich, Karlene A, Montgomery, Stephen B, Bassik, Michael C

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Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain von Marschallinger, Julia, Iram, Tal, Zardeneta, Macy, Lee, Song E., Lehallier, Benoit, Haney, Michael S., Pluvinage, John V., Mathur, Vidhu, Hahn, Oliver, Morgens, David W., Kim, Justin, Tevini, Julia, Felder, Thomas K., Wolinski, Heimo, Bertozzi, Carolyn R., Bassik, Michael C., Aigner, Ludwig, Wyss-Coray, Tony

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LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP von Lahey, Lauren J., Mardjuki, Rachel E., Wen, Xianlan, Hess, Gaelen T., Ritchie, Christopher, Carozza, Jacqueline A., Böhnert, Volker, Maduke, Merritt, Bassik, Michael C., Li, Lingyin

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Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development von Phanstiel, Douglas H., Van Bortle, Kevin, Spacek, Damek, Hess, Gaelen T., Shamim, Muhammad Saad, Machol, Ido, Love, Michael I., Aiden, Erez Lieberman, Bassik, Michael C., Snyder, Michael P.

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Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens von Morgens, David W., Wainberg, Michael, Boyle, Evan A., Ursu, Oana, Araya, Carlos L., Tsui, C. Kimberly, Haney, Michael S., Hess, Gaelen T., Han, Kyuho, Jeng, Edwin E., Li, Amy, Snyder, Michael P., Greenleaf, William J., Kundaje, Anshul, Bassik, Michael C.

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CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity von Kramer, Nicholas J., Haney, Michael S., Morgens, David W., Jovičić, Ana, Couthouis, Julien, Li, Amy, Ousey, James, Ma, Rosanna, Bieri, Gregor, Tsui, C. Kimberly, Shi, Yingxiao, Hertz, Nicholas T., Tessier-Lavigne, Marc, Ichida, Justin K., Bassik, Michael C., Gitler, Aaron D.

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CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities von Han, Kyuho, Pierce, Sarah E., Li, Amy, Spees, Kaitlyn, Anderson, Gray R., Seoane, Jose A., Lo, Yuan-Hung, Dubreuil, Michael, Olivas, Micah, Kamber, Roarke A., Wainberg, Michael, Kostyrko, Kaja, Kelly, Marcus R., Yousefi, Maryam, Simpkins, Scott W., Yao, David, Lee, Keonil, Kuo, Calvin J., Jackson, Peter K., Sweet-Cordero, Alejandro, Kundaje, Anshul, Gentles, Andrew J., Curtis, Christina, Winslow, Monte M., Bassik, Michael C.

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Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7 von Wisnovsky, Simon, Möckl, Leonhard, Malaker, Stacy A., Pedram, Kayvon, Hess, Gaelen T., Riley, Nicholas M., Gray, Melissa A., Smith, Benjamin A. H., Bassik, Michael C., Moerner, W. E., Bertozzi, Carolyn R.

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Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells von Kampmann, Martin, Bassik, Michael C, Weissman, Jonathan S

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation von Cheng, Weiwei, Wang, Shaopeng, Zhang, Zhe, Morgens, David W., Hayes, Lindsey R., Lee, Soojin, Portz, Bede, Xie, Yongzhi, Nguyen, Baotram V., Haney, Michael S., Yan, Shirui, Dong, Daoyuan, Coyne, Alyssa N., Yang, Junhua, Xian, Fengfan, Cleveland, Don W., Qiu, Zhaozhu, Rothstein, Jeffrey D., Shorter, James, Gao, Fen-Biao, Bassik, Michael C., Sun, Shuying

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Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens von Haney, Michael S., Bohlen, Christopher J., Morgens, David W., Ousey, James A., Barkal, Amira A., Tsui, C. Kimberly, Ego, Braeden K., Levin, Roni, Kamber, Roarke A., Collins, Hannah, Tucker, Andrew, Li, Amy, Vorselen, Daan, Labitigan, Lorenzo, Crane, Emily, Boyle, Evan, Jiang, Lihua, Chan, Joanne, Rincón, Esther, Greenleaf, William J., Li, Billy, Snyder, Michael P., Weissman, Irving L., Theriot, Julie A., Collins, Sean R., Barres, Ben A., Bassik, Michael C.

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Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements von Tycko, Josh, Wainberg, Michael, Marinov, Georgi K., Ursu, Oana, Hess, Gaelen T., Ego, Braeden K., Aradhana, Li, Amy, Truong, Alisa, Trevino, Alexandro E., Spees, Kaitlyn, Yao, David, Kaplow, Irene M., Greenside, Peyton G., Morgens, David W., Phanstiel, Douglas H., Snyder, Michael P., Bintu, Lacramioara, Greenleaf, William J., Kundaje, Anshul, Bassik, Michael C.

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