Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes von Di Micco, Raffaella, Fontanals-Cirera, Barbara, Low, Vivien, Ntziachristos, Panagiotis, Yuen, Stephanie K, Lovell, Claudia D, Dolgalev, Igor, Yonekubo, Yoshiya, Zhang, Guangtao, Rusinova, Elena, Gerona-Navarro, Guillermo, Cañamero, Marta, Ohlmeyer, Michael, Aifantis, Iannis, Zhou, Ming-Ming, Tsirigos, Aristotelis, Hernando, Eva

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miR-30b/30d Regulation of GalNAc Transferases Enhances Invasion and Immunosuppression during Metastasis von Gaziel-Sovran, Avital, Segura, Miguel F., Di Micco, Raffaella, Collins, Mary K., Hanniford, Douglas, Vega-Saenz de Miera, Eleazar, Rakus, John F., Dankert, John F., Shang, Shulian, Kerbel, Robert S., Bhardwaj, Nina, Shao, Yongzhao, Darvishian, Farbod, Zavadil, Jiri, Erlebacher, Adrian, Mahal, Lara K., Osman, Iman, Hernando, Eva

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Cellular senescence in ageing: from mechanisms to therapeutic opportunities von Di Micco, Raffaella, Krizhanovsky, Valery, Baker, Darren, d’Adda di Fagagna, Fabrizio

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Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis von Biavasco, Riccardo, Lettera, Emanuele, Giannetti, Kety, Gilioli, Diego, Beretta, Stefano, Conti, Anastasia, Scala, Serena, Cesana, Daniela, Gallina, Pierangela, Norelli, Margherita, Basso-Ricci, Luca, Bondanza, Attilio, Cavalli, Giulio, Ponzoni, Maurilio, Dagna, Lorenzo, Doglioni, Claudio, Aiuti, Alessandro, Merelli, Ivan, Di Micco, Raffaella, Montini, Eugenio

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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response von Schiroli, Giulia, Conti, Anastasia, Ferrari, Samuele, della Volpe, Lucrezia, Jacob, Aurelien, Albano, Luisa, Beretta, Stefano, Calabria, Andrea, Vavassori, Valentina, Gasparini, Patrizia, Salataj, Eralda, Ndiaye-Lobry, Delphine, Brombin, Chiara, Chaumeil, Julie, Montini, Eugenio, Merelli, Ivan, Genovese, Pietro, Naldini, Luigi, Di Micco, Raffaella

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Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer von Sulli, Gabriele, Di Micco, Raffaella, di Fagagna, Fabrizio d'Adda

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An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro‐inflammatory... von Gnani, Daniela, Crippa, Stefania, della Volpe, Lucrezia, Rossella, Valeria, Conti, Anastasia, Lettera, Emanuele, Rivis, Silvia, Ometti, Marco, Fraschini, Gianfranco, Bernardo, Maria Ester, Di Micco, Raffaella

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p53 activation: a checkpoint for precision genome editing? von Conti, Anastasia, Di Micco, Raffaella

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication von d'Adda di Fagagna, Fabrizio, Di Micco, Raffaella, Fumagalli, Marzia, Cicalese, Angelo, Piccinin, Sara, Gasparini, Patrizia, Luise, Chiara, Schurra, Catherine, Garre', Massimiliano, Giovanni Nuciforo, Paolo, Bensimon, Aaron, Maestro, Roberta, Giuseppe Pelicci, Pier

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Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia von Naldini, Matteo Maria, Casirati, Gabriele, Barcella, Matteo, Rancoita, Paola Maria Vittoria, Cosentino, Andrea, Caserta, Carolina, Pavesi, Francesca, Zonari, Erika, Desantis, Giacomo, Gilioli, Diego, Carrabba, Matteo Giovanni, Vago, Luca, Bernardi, Massimo, Di Micco, Raffaella, Di Serio, Clelia, Merelli, Ivan, Volpin, Monica, Montini, Eugenio, Ciceri, Fabio, Gentner, Bernhard

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Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer von Mercurio, Ciro, dal Zuffo, Roberto, Liontos, Michalis, d'Ario, Giovanni, Hahn, William C, Gorgoulis, Vassilis, Dobreva, Miryana, Minucci, Saverio, Sulli, Gabriele, Montani, Erica, d'Adda di Fagagna, Fabrizio, Matti, Valentina, Gargiulo, Gaetano, Di Micco, Raffaella, Botrugno, Oronza A

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Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency von Milardi, Giulia, Di Lorenzo, Biagio, Gerosa, Jolanda, Barzaghi, Federica, Di Matteo, Gigliola, Omrani, Maryam, Jofra, Tatiana, Merelli, Ivan, Barcella, Matteo, Filippini, Matteo, Conti, Anastasia, Ferrua, Francesca, Pozzo Giuffrida, Francesco, Dionisio, Francesca, Rovere‐Querini, Patrizia, Marktel, Sarah, Assanelli, Andrea, Piemontese, Simona, Brigida, Immacolata, Zoccolillo, Matteo, Cirillo, Emilia, Giardino, Giuliana, Danieli, Maria Giovanna, Specchia, Fernando, Pacillo, Lucia, Di Cesare, Silvia, Giancotta, Carmela, Romano, Francesca, Matarese, Alessandro, Chetta, Alfredo Antonio, Trimarchi, Matteo, Laurenzi, Andrea, De Pellegrin, Maurizio, Darin, Silvia, Montin, Davide, Marinoni, Maddalena, Dellepiane, Rosa Maria, Sordi, Valeria, Lougaris, Vassilios, Vacca, Angelo, Melzi, Raffaella, Nano, Rita, Azzari, Chiara, Bongiovanni, Lucia, Pignata, Claudio, Cancrini, Caterina, Plebani, Alessandro, Piemonti, Lorenzo, Petrovas, Constantinos, Di Micco, Raffaella, Ponzoni, Maurilio, Aiuti, Alessandro, Cicalese, Maria Pia, Fousteri, Georgia

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Epigenetic Therapies for Acute Myeloid Leukemia and Their Immune-Related Effects von Gambacorta, Valentina, Gnani, Daniela, Vago, Luca, Di Micco, Raffaella

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The transcription factor HIF2α partakes in the differentiation block of acute myeloid leukemia von Magliulo, Daniela, Simoni, Matilde, Caserta, Carolina, Fracassi, Cristina, Belluschi, Serena, Giannetti, Kety, Pini, Raffaella, Zapparoli, Ettore, Beretta, Stefano, Uggè, Martina, Draghi, Eleonora, Rossari, Federico, Coltella, Nadia, Tresoldi, Cristina, Morelli, Marco J, Di Micco, Raffaella, Gentner, Bernhard, Vago, Luca, Bernardi, Rosa

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Goodbye, senescent cells: CAR-T cells unleashed to fight ageing von Di Micco, Raffaella

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TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells von Cianciotti, Beatrice Claudia, Magnani, Zulma Irene, Ugolini, Alessia, Camisa, Barbara, Merelli, Ivan, Vavassori, Valentina, Potenza, Alessia, Imparato, Antonio, Manfredi, Francesco, Abbati, Danilo, Perani, Laura, Spinelli, Antonello, Shifrut, Eric, Ciceri, Fabio, Vago, Luca, Di Micco, Raffaella, Naldini, Luigi, Genovese, Pietro, Ruggiero, Eliana, Bonini, Chiara

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Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients von Marcovecchio, Genni Enza, Ferrua, Francesca, Fontana, Elena, Beretta, Stefano, Genua, Marco, Bortolomai, Ileana, Conti, Anastasia, Montin, Davide, Cascarano, Maria Teresa, Bergante, Sonia, D’Oria, Veronica, Giamberti, Alessandro, Amodio, Donato, Cancrini, Caterina, Carotti, Adriano, Di Micco, Raffaella, Merelli, Ivan, Bosticardo, Marita, Villa, Anna

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A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34 + hematopoietic cells while allowing the detection of tumorigenic expansion von Ritter, Paolo, Oliveto, Stefania, Cordiglieri, Chiara, Fasciani, Alessandra, Di Buduo, Christian Andrea, Della Volpe, Lucrezia, Bocconi, Alberto, Conci, Claudio, Miguel, Carolina Paula, Di Micco, Raffaella, Balduini, Alessandra, Raimondi, Manuela Teresa, Biffo, Stefano

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Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene von Fontanals-Cirera, Barbara, Hasson, Dan, Vardabasso, Chiara, Di Micco, Raffaella, Agrawal, Praveen, Chowdhury, Asif, Gantz, Madeleine, de Pablos-Aragoneses, Ana, Morgenstern, Ari, Wu, Pamela, Filipescu, Dan, Valle-Garcia, David, Darvishian, Farbod, Roe, Jae-Seok, Davies, Michael A., Vakoc, Christopher R., Hernando, Eva, Bernstein, Emily

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Breaking news: high-speed race ends in arrest – how oncogenes induce senescence von Di Micco, Raffaella, Fumagalli, Marzia, d’Adda di Fagagna, Fabrizio

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