Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors von Savill, Kristin M. Zimmerman, Lee, Brian B., Oeh, Jason, Lin, Jie, Lin, Eva, Chung, Wei-Jen, Young, Amy, Chen, Wennie, Miś, Monika, Mesh, Kathryn, Eastham, Jeffrey, Gnad, Florian, Jiang, Zhaoshi, Stawiski, Eric W., Haley, Benjamin, Daemen, Anneleen, Wang, Xiaojing, Koeppen, Hartmut, Modrusan, Zora, Martin, Scott E., Sampath, Deepak, Lin, Kui

Volltext

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities von Hart, Traver, Chandrashekhar, Megha, Aregger, Michael, Steinhart, Zachary, Brown, Kevin R., MacLeod, Graham, Mis, Monika, Zimmermann, Michal, Fradet-Turcotte, Amelie, Sun, Song, Mero, Patricia, Dirks, Peter, Sidhu, Sachdev, Roth, Frederick P., Rissland, Olivia S., Durocher, Daniel, Angers, Stephane, Moffat, Jason

Volltext

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice von Tao, Yuyong, Mis, Monika, Blazer, Levi, Ustav, Jnr, Mart, Steinhart, Zachary, Chidiac, Rony, Kubarakos, Elli, O'Brien, Siobhan, Wang, Xiaomei, Jarvik, Nick, Patel, Nish, Adams, Jarrett, Moffat, Jason, Angers, Stephane, Sidhu, Sachdev S

Volltext

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2 von Suryamohan, Kushal, Diwanji, Devan, Stawiski, Eric W., Gupta, Ravi, Miersch, Shane, Liu, Jiang, Chen, Chao, Jiang, Ying-Ping, Fellouse, Frederic A., Sathirapongsasuti, J. Fah, Albers, Patrick K., Deepak, Tanneeru, Saberianfar, Reza, Ratan, Aakrosh, Washburn, Gavin, Mis, Monika, Santhosh, Devi, Somasekar, Sneha, Hiranjith, G. H., Vargas, Derek, Mohan, Sangeetha, Phalke, Sameer, Kuriakose, Boney, Antony, Aju, Ustav Jr, Mart, Schuster, Stephan C., Sidhu, Sachdev, Junutula, Jagath R., Jura, Natalia, Seshagiri, Somasekar

Volltext

IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers von Mis, Monika, O'Brien, Siobhan, Steinhart, Zachary, Lin, Sichun, Hart, Traver, Moffat, Jason, Angers, Stephane

Volltext

A Genome‐Wide CRISPR‐Cas9 Screen Identifies Importin‐β11 as a Required Factor for β‐catenin Signaling in Colon Cancer von Mis, Monika, Steinhart, Zachary, Angers, Stephane

Volltext

SCFFBXW7 regulates G2‐M progression through control of CCNL1 ubiquitination von O'Brien, Siobhan, Kelso, Susan, Steinhart, Zachary, Orlicky, Stephen, Mis, Monika, Kim, Yunhye, Lin, Sichun, Sicheri, Frank, Angers, Stephane

Volltext

SCF FBXW7 regulates G2-M progression through control of CCNL1 ubiquitination von O'Brien, Siobhan, Kelso, Susan, Steinhart, Zachary, Orlicky, Stephen, Mis, Monika, Kim, Yunhye, Lin, Sichun, Sicheri, Frank, Angers, Stephane

Volltext

A site-directed mutagenesis study of the MdmX RING domain von Egorova, Olga, Sheng, Yi

Volltext

Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView von Kudo, Takamasa, Meireles, Ana M, Moncada, Reuben, Chen, Yushu, Wu, Ping, Gould, Joshua, Hu, Xiaoyu, Kornfeld, Opher, Jesudason, Rajiv, Foo, Conrad, Höckendorf, Burkhard, Corrada Bravo, Hector, Town, Jason P, Wei, Runmin, Rios, Antonio, Chandrasekar, Vineethkrishna, Heinlein, Melanie, Chuong, Amy S, Cai, Shuangyi, Lu, Cherry Sakura, Coelho, Paula, Mis, Monika, Celen, Cemre, Kljavin, Noelyn, Jiang, Jian, Richmond, David, Thakore, Pratiksha, Benito-Gutiérrez, Elia, Geiger-Schuller, Kathryn, Hleap, Jose Sergio, Kayagaki, Nobuhiko, de Sousa E Melo, Felipe, McGinnis, Lisa, Li, Bo, Singh, Avtar, Garraway, Levi, Rozenblatt-Rosen, Orit, Regev, Aviv, Lubeck, Eric

Volltext

Abstract PR03: High-resolution detection of fitness genes and genotype-specific cancer vulnerabilities with CRISPR-Cas9 screens von Hart, Traver, Chandrashekhar, Megha, Aregger, Michael, Steinhart, Zachary, Brown, Kevin R., Macleod, Graham, Mis, Monika, Zimmermann, Michal, Fradet-Turcotte, Amelie, Sun, Song, Driks, Peter, Sidhu, Sachdev, Roth, Frederick P., Rissland, Olivia S., Durocher, Daniel, Angers, Stephane, Moffat, Jason

Volltext

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates[S] von Coyaud, Etienne, Mis, Monika, Laurent, Estelle M.N., Dunham, Wade H., Couzens, Amber L., Robitaille, Melanie, Gingras, Anne-Claude, Angers, Stephane, Raught, Brian

Volltext

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice von Tao, Yuyong, Mis, Monika, Blazer, Levi, Ustav, Mart, Steinhart, Zachary, Chidiac, Rony, Kubarakos, Elli, O'Brien, Siobhan, Wang, Xiaomei, Jarvik, Nick, Patel, Nish, Adams, Jarrett, Moffat, Jason, Angers, Stephane, Sidhu, Sachdev S

Volltext

Effect of dietary fibre polysaccharides on structure and thermal properties of gluten proteins – A study on gluten dough with application of FT-Raman spectroscopy, TGA and DSC von Nawrocka, Agnieszka, Szymańska-Chargot, Monika, Miś, Antoni, Wilczewska, Agnieszka Z., Markiewicz, Karolina H.

Volltext

Dietary Fiber-Induced Changes in the Structure and Thermal Properties of Gluten Proteins Studied by Fourier Transform-Raman Spectroscopy and Thermogravimetry von Nawrocka, Agnieszka, Szymańska-Chargot, Monika, Miś, Antoni, Wilczewska, Agnieszka Z, Markiewicz, Karolina H

Volltext

Effect of cinnamic acid and its derivatives on structure of gluten proteins – A study on model dough with application of FT-Raman spectroscopy von Krekora, Magdalena, Szymańska-Chargot, Monika, Niewiadomski, Zbigniew, Miś, Antoni, Nawrocka, Agnieszka

Volltext

Aggregation of gluten proteins in model dough after fibre polysaccharide addition von Nawrocka, Agnieszka, Szymańska-Chargot, Monika, Miś, Antoni, Wilczewska, Agnieszka Z., Markiewicz, Karolina H.

Volltext

Effect of fluorescence dyes on wet gluten structure studied with fluorescence and FT-Raman spectroscopies von Nawrocka, Agnieszka, Rumińska, Weronika, Szymańska-Chargot, Monika, Niewiadomski, Zbigniew, Miś, Antoni

Volltext

Effect of moisturizing pre-treatment of dietary fibre preparations on formation of gluten network during model dough mixing – A study with application of FT-IR and FT-Raman spectro... von Nawrocka, Agnieszka, Krekora, Magdalena, Niewiadomski, Zbigniew, Szymańska-Chargot, Monika, Krawęcka, Ada, Sobota, Aldona, Miś, Antoni

Volltext

Characteristics of Relationships Between Structure of Gluten Proteins and Dough Rheology – Influence of Dietary Fibres Studied by FT-Raman Spectroscopy von Nawrocka, Agnieszka, Miś, Antoni, Szymańska-Chargot, Monika

Volltext