Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets von Zhao, Jing Hua, Stacey, David, Eriksson, Niclas, Macdonald-Dunlop, Erin, Hedman, Åsa K., Kalnapenkis, Anette, Enroth, Stefan, Cozzetto, Domenico, Digby-Bell, Jonathan, Marten, Jonathan, Folkersen, Lasse, Herder, Christian, Jonsson, Lina, Bergen, Sarah E., Gieger, Christian, Needham, Elise J., Surendran, Praveen, Paul, Dirk S., Polasek, Ozren, Thorand, Barbara, Grallert, Harald, Roden, Michael, Võsa, Urmo, Esko, Tonu, Hayward, Caroline, Johansson, Åsa, Gyllensten, Ulf, Powell, Nick, Hansson, Oskar, Mattsson-Carlgren, Niklas, Joshi, Peter K., Danesh, John, Padyukov, Leonid, Klareskog, Lars, Landén, Mikael, Wilson, James F., Siegbahn, Agneta, Wallentin, Lars, Mälarstig, Anders, Butterworth, Adam S., Peters, James E.

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Genetic risk scores and family history as predictors of schizophrenia in Nordic registers von Lu, Y., Pouget, J. G., Andreassen, O. A., Djurovic, S., Esko, T., Hultman, C. M., Metspalu, A., Milani, L., Werge, T., Sullivan, P. F.

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A cross-disorder dosage sensitivity map of the human genome von Collins, Ryan L., Glessner, Joseph T., Porcu, Eleonora, Lepamets, Maarja, Brandon, Rhonda, Lauricella, Christopher, Han, Lide, Morley, Theodore, Niestroj, Lisa-Marie, Ulirsch, Jacob, Everett, Selin, Howrigan, Daniel P., Boone, Philip M., Fu, Jack, Karczewski, Konrad J., Kellaris, Georgios, Lowther, Chelsea, Lucente, Diane, Mohajeri, Kiana, Nõukas, Margit, Nuttle, Xander, Samocha, Kaitlin E., Trinh, Mi, Ullah, Farid, Võsa, Urmo, Metspalu, Andres, Mägi, Reedik, Nelis, Mari, Milani, Lili, Esko, Tõnu, Hurles, Matthew E., Aradhya, Swaroop, Davis, Erica E., Finucane, Hilary, Gusella, James F., Janze, Aura, Katsanis, Nicholas, Matyakhina, Ludmila, Neale, Benjamin M., Sanders, David, Warren, Stephanie, Hodge, Jennelle C., Lal, Dennis, Ruderfer, Douglas M., Meck, Jeanne, Mägi, Reedik, Esko, Tõnu, Reymond, Alexandre, Kutalik, Zoltán, Hakonarson, Hakon, Sunyaev, Shamil, Brand, Harrison, Talkowski, Michael E.

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Gut microbiome in endometriosis: a cohort study on 1000 individuals von Pérez-Prieto, Inmaculada, Vargas, Eva, Salas-Espejo, Eduardo, Lüll, Kreete, Canha-Gouveia, Analuce, Pérez, Laura Antequera, Fontes, Juan, Salumets, Andres, Andreson, Reidar, Aasmets, Oliver, Whiteson, Katrine, Org, Elin, Altmäe, Signe

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An epidemiological perspective of personalized medicine: the Estonian experience von Milani, L., Leitsalu, L., Metspalu, A.

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Genetic susceptibility to temporomandibular joint involvement in juvenile idiopathic arthritis von Niibo, P., Nikopensius, T., Jagomägi, T., Voog, Ü., Haller, T., Tõnisson, N., Metspalu, A., Saag, M., Pruunsild, C.

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Polymorphic Variation in TPMT Is the Principal Determinant of TPMT Phenotype: A Meta‐Analysis of Three Genome‐Wide Association Studies von Tamm, R, Mägi, R, Tremmel, R, Winter, S, Mihailov, E, Smid, A, Möricke, A, Klein, K, Schrappe, M, Stanulla, M, Houlston, R, Weinshilboum, R, Mlinarič Raščan, Irena, Metspalu, A, Milani, L, Schwab, M, Schaeffeler, E

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A Missense Mutation in DUSP6 is Associated with Class III Malocclusion von Nikopensius, T., Saag, M., Jagomägi, T., Annilo, T., Kals, M., Kivistik, P.A., Milani, L., Metspalu, A.

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Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles von Noordam, Raymond, Laell, Kristi, Smit, Roelof A. J., Laisk, Triin, Loos, Ruth J. F., Magi, Reedik, van Dijk, Ko Willems, van Heemst, Diana

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Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss von Trpchevska, Natalia, Freidin, Maxim B., Broer, Linda, Oosterloo, Berthe C., Yao, Shuyang, Zhou, Yitian, Vona, Barbara, Bishop, Charles, Bizaki-Vallaskangas, Argyro, Canlon, Barbara, Castellana, Fabio, Chasman, Daniel I., Cherny, Stacey, Christensen, Kaare, Concas, Maria Pina, Correa, Adolfo, Elkon, Ran, Metspalu, Andres, Nelis, Mari, Mägi, Reedik, Esko, Tõnu, Mengel-From, Jonas, Gao, Yan, Giersch, Anne B.S., Girotto, Giorgia, Gudjonsson, Alexander, Gudnason, Vilmundur, Heard-Costa, Nancy L., Hertzano, Ronna, Hjelmborg, Jacob v.B., Hjerling-Leffler, Jens, Hoffman, Howard J., Kaprio, Jaakko, Kettunen, Johannes, Krebs, Kristi, Kähler, Anna K., Lallemend, Francois, Launer, Lenore J., Lee, I-Min, Leonard, Hampton, Li, Chuan-Ming, Lowenheim, Hubert, Magnusson, Patrik K.E., van Meurs, Joyce, Milani, Lili, Morton, Cynthia C., Mäkitie, Antti, Nalls, Mike A., Nardone, Giuseppe Giovanni, Nygaard, Marianne, Palviainen, Teemu, Pratt, Sheila, Quaranta, Nicola, Rämö, Joel, Saarentaus, Elmo, Sardone, Rodolfo, Satizabal, Claudia L., Schweinfurth, John M., Seshadri, Sudha, Shiroma, Eric, Shulman, Eldad, Simonsick, Eleanor, Spankovich, Christopher, Tropitzsch, Anke, Lauschke, Volker M., Sullivan, Patrick F., Goedegebure, Andre, Cederroth, Christopher R., Williams, Frances M.K., Nagtegaal, Andries Paul

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The individual and global impact of copy-number variants on complex human traits von Auwerx, Chiara, Lepamets, Maarja, Sadler, Marie C., Patxot, Marion, Stojanov, Miloš, Baud, David, Mägi, Reedik, Esko, Tõnu, Metspalu, Andres, Milani, Lili, Mägi, Reedik, Nelis, Mari, Porcu, Eleonora, Reymond, Alexandre, Kutalik, Zoltán

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A KATP channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila von Allebrandt, K V, Amin, N, Müller-Myhsok, B, Esko, T, Teder-Laving, M, Azevedo, R V D M, Hayward, C, van Mill, J, Vogelzangs, N, Green, E W, Melville, S A, Lichtner, P, Wichmann, H-E, Oostra, B A, Janssens, A C J W, Campbell, H, Wilson, J F, Hicks, A A, Pramstaller, P P, Dogas, Z, Rudan, I, Merrow, M, Penninx, B, Kyriacou, C P, Metspalu, A, van Duijn, C M, Meitinger, T, Roenneberg, T

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Genome-wide association study identifies five risk loci for pernicious anemia von Laisk, Triin, Lepamets, Maarja, Koel, Mariann, Abner, Erik, Mägi, Reedik

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Toward a roadmap in global biobanking for health von HARRIS, Jennifer R, BURTON, Paul, FORTIER, Isabel, HAINAUT, Pierre, HEWITT, Robert, KAYE, Jane, LITTON, Jan-Eric, METSPALU, Andres, OLLIER, Bill, PALMER, Lyle J, PALOTIE, Aarno, PASTERK, Markus, KNOPPERS, Bartha Maria, PEROLA, Markus, RIEGMAN, Peter Hj, OMMEN, Gert-Janvan, YUILLE, Martin, ZATLOUKAL, Kurt, LINDPAINTNER, Klaus, BLEDSOE, Marianna, BROOKES, Anthony J, BUDIN-LJØSNE, Isabelle, CHISHOLM, Rex, COX, David, DESCHENES, Mylène

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Genetic drivers and cellular selection of female mosaic X chromosome loss von Liu, Aoxing, Genovese, Giulio, Zhao, Yajie, Pirinen, Matti, Zekavat, Seyedeh M., Kentistou, Katherine A., Yang, Zhiyu, Yu, Kai, Vlasschaert, Caitlyn, Liu, Xiaoxi, Brown, Derek W., Hudjashov, Georgi, Gorman, Bryan R., Dennis, Joe, Zhou, Weiyin, Momozawa, Yukihide, Pyarajan, Saiju, Tuzov, Valdislav, Pajuste, Fanny-Dhelia, Aavikko, Mervi, Sipilä, Timo P., Ghazal, Awaisa, Huang, Wen-Yi, Freedman, Neal D., Song, Lei, Gardner, Eugene J., Sankaran, Vijay G., Palotie, Aarno, Ollila, Hanna M., Tukiainen, Taru, Chanock, Stephen J., Mägi, Reedik, Natarajan, Pradeep, Daly, Mark J., Bick, Alexander, McCarroll, Steven A., Terao, Chikashi, Loh, Po-Ru, Ganna, Andrea, Perry, John R. B., Machiela, Mitchell J.

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Contribution of schizophrenia polygenic burden to longitudinal phenotypic variance in 22q11.2 deletion syndrome von Alver, Maris, Mancini, Valentina, Läll, Kristi, Schneider, Maude, Romano, Luciana, Mägi, Reedik, Dermitzakis, Emmanouil T., Eliez, Stephan, Reymond, Alexandre

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Long-range regulatory effects of Neandertal DNA in modern humans von Yermakovich, Danat, Pankratov, Vasili, Võsa, Urmo, Yunusbayev, Bayazit, Dannemann, Michael

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Prioritizing autoimmunity risk variants for functional analyses by fine-mapping mutations under natural selection von Pankratov, Vasili, Yunusbaeva, Milyausha, Ryakhovsky, Sergei, Zarodniuk, Maksym, Yunusbayev, Bayazit

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Genetic determinants of plasma protein levels in the Estonian population von Kalnapenkis, Anette, Jõeloo, Maarja, Lepik, Kaido, Kukuškina, Viktorija, Kals, Mart, Alasoo, Kaur, Mägi, Reedik, Esko, Tõnu, Võsa, Urmo

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Replication and meta-analysis of TMEM132D gene variants in panic disorder von Erhardt, A, Akula, N, Schumacher, J, Czamara, D, Karbalai, N, Müller-Myhsok, B, Mors, O, Borglum, A, Kristensen, A S, Woldbye, D P D, Koefoed, P, Eriksson, E, Maron, E, Metspalu, A, Nurnberger, J, Philibert, R A, Kennedy, J, Domschke, K, Reif, A, Deckert, J, Otowa, T, Kawamura, Y, Kaiya, H, Okazaki, Y, Tanii, H, Tokunaga, K, Sasaki, T, Ioannidis, J P A, McMahon, F J, Binder, E B

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