Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation von Zhang, Zeda, Zhou, Chuanli, Li, Xiaoling, Barnes, Spencer D., Deng, Su, Hoover, Elizabeth, Chen, Chi-Chao, Lee, Young Sun, Zhang, Yanxiao, Wang, Choushi, Metang, Lauren A., Wu, Chao, Tirado, Carla Rodriguez, Johnson, Nickolas A., Wongvipat, John, Navrazhina, Kristina, Cao, Zhen, Choi, Danielle, Huang, Chun-Hao, Linton, Eliot, Chen, Xiaoping, Liang, Yupu, Mason, Christopher E., de Stanchina, Elisa, Abida, Wassim, Lujambio, Amaia, Li, Sheng, Lowe, Scott W., Mendell, Joshua T., Malladi, Venkat S., Sawyers, Charles L., Mu, Ping

Volltext

Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer von Li, Xiaoling, Wang, Yunguan, Deng, Su, Zhu, Guanghui, Wang, Choushi, Johnson, Nickolas A., Zhang, Zeda, Tirado, Carla Rodriguez, Xu, Yaru, Metang, Lauren A., Gonzalez, Julisa, Mukherji, Atreyi, Ye, Jianfeng, Yang, Yuqiu, Peng, Wei, Tang, Yitao, Hofstad, Mia, Xie, Zhiqun, Yoon, Heewon, Chen, Liping, Liu, Xihui, Chen, Sujun, Zhu, Hong, Strand, Douglas, Liang, Han, Raj, Ganesh, He, Housheng Hansen, Mendell, Joshua T., Li, Bo, Wang, Tao, Mu, Ping

Volltext

UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance von Rodriguez Tirado, Carla, Wang, Choushi, Li, Xiaoling, Deng, Su, Gonzalez, Julisa, Johnson, Nickolas A., Xu, Yaru, Metang, Lauren A., Sundar Rajan, Medha, Yang, Yuqiu, Yin, Yi, Hofstad, Mia, Raj, Ganesh V., Zhang, Song, Lemoff, Andrew, He, Wei, Fan, Jie, Wang, Yunguan, Wang, Tao, Mu, Ping

Volltext

Ectopic JAK-STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance von Deng, Su, Wang, Choushi, Wang, Yunguan, Xu, Yaru, Li, Xiaoling, Johnson, Nickolas A, Mukherji, Atreyi, Lo, U-Ging, Xu, Lingfan, Gonzalez, Julisa, Metang, Lauren A, Ye, Jianfeng, Tirado, Carla Rodriguez, Rodarte, Kathia, Zhou, Yinglu, Xie, Zhiqun, Arana, Carlos, Annamalai, Valli, Liu, Xihui, Vander Griend, Donald J, Strand, Douglas, Hsieh, Jer-Tsong, Li, Bo, Raj, Ganesh, Wang, Tao, Mu, Ping

Volltext

Author Correction: Ectopic JAK–STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance von Deng, Su, Wang, Choushi, Wang, Yunguan, Xu, Yaru, Li, Xiaoling, Johnson, Nickolas A., Mukherji, Atreyi, Lo, U-Ging, Xu, Lingfan, Gonzalez, Julisa, Metang, Lauren A., Ye, Jianfeng, Tirado, Carla Rodriguez, Rodarte, Kathia, Zhou, Yinglu, Xie, Zhiqun, Arana, Carlos, Annamalai, Valli, Liu, Xihui, Vander Griend, Donald J., Strand, Douglas, Hsieh, Jer-Tsong, Li, Bo, Raj, Ganesh, Wang, Tao, Mu, Ping

Volltext

Active enhancer and chromatin accessibility landscapes chart the regulatory network of primary multiple myeloma von Jin, Yi, Chen, Kenian, De Paepe, Ayla, Hellqvist, Eva, Krstic, Aleksandra D., Metang, Lauren, Gustafsson, Charlotte, Davis, Richard E., Levy, Yair M., Surapaneni, Rakesh, Wallblom, Ann, Nahi, Hareth, Mansson, Robert, Lin, Yin C.

Volltext

Abstract LB-A28: Super-enhancer signatures of pancreatic ductal adenocarcinoma and associated fibroblasts von Hussein, Shaimaa, Noel, Pawan, Chen, Kenian, Metang, Lauren, Von Hoff, Daniel, Han, Haiyong, Lin, Yin

Volltext

Abstract 3891: Epigenetic rewiring promotes antiandrogen resistance and metastasis via heterogenous oncogenic drivers in prostate cancer von li, Xiaong, Deng, Su, Gonzalez, Julisa, Tirado, Carla Rodriguez, Wang, Choushi, Johnson, Nickolas A., Metang, Lauren, Mu, Ping

Volltext

Abstract NG06: CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity von Zhang, Zeda, Zhou, Chuanli, Li, Xiaoling, Barnes, Spencer, Deng, Su, Hoover, Elizabeth, Chen, Chi-Chao, Lee, Young Sun, Wang, Choushi, Tirado, Carla, Metang, Lauren, Johnson, Nickolas, Wongvipat, John, Navrazhina, Kristina, Cao, Zhen, Abida, Wassim, Lujambio, Amaia, Li, Sheng, Malladi, Vankat, Sawyers, Charles, Mu, Ping

Volltext