Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling von Hultberg, Anna, Morello, Virginia, Huyghe, Leander, De Jonge, Natalie, Blanchetot, Christophe, Hanssens, Valérie, De Boeck, Gitte, Silence, Karen, Festjens, Els, Heukers, Raimond, Roux, Benjamin, Lamballe, Fabienne, Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Maina, Flavio, Brouckaert, Peter, Saunders, Michael, Thibault, Alain, Dreier, Torsten, de Haard, Hans, Michieli, Paolo

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When iron met phosphines: a happy marriage for reduction catalysis von Misal Castro, Luis C, Li, Haoquan, Sortais, Jean-Baptiste, Darcel, Christophe

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INSIGHT 2: a phase II study of tepotinib plus osimertinib in MET -amplified NSCLC and first-line osimertinib resistance von F Smit, Egbert, Dooms, Christophe, Raskin, Jo, Nadal, Ernest, Tho, Lye M, Le, Xiuning, Mazieres, Julien, S Hin, How, Morise, Masahire, W Zhu, Viola, Tan, Daniel, H Holmberg, Kristina, Ellers-Lenz, Barbara, Adrian, Svenja, Brutlach, Sabine, Schumacher, Karl M, Karachaliou, Niki, Wu, Yi-Long

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In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models von Hughes, Paul E, Rex, Karen, Caenepeel, Sean, Yang, Yajing, Zhang, Yihong, Broome, Martin A, Kha, Hue T, Burgess, Teresa L, Amore, Benny, Kaplan-Lefko, Paula J, Moriguchi, Jodi, Werner, Jonathan, Damore, Michael A, Baker, Daniel, Choquette, Deborah M, Harmange, Jean-Christophe, Radinsky, Robert, Kendall, Richard, Dussault, Isabelle, Coxon, Angela

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Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET) von Weiss, Emmanuel, de la Peña-Ramirez, Carlos, Aguilar, Ferran, Lozano, Juan-Jose, Sánchez-Garrido, Cristina, Sierra, Patricia, Martin, Pedro Izquierdo-Bueno, Diaz, Juan Manuel, Fenaille, François, Castelli, Florence A, Gustot, Thierry, Laleman, Wim, Albillos, Agustín, Alessandria, Carlo, Domenicali, Marco, Caraceni, Paolo, Piano, Salvatore, Saliba, Faouzi, Zeuzem, Stefan, Gerbes, Alexander L, Wendon, Julia A, Jansen, Christian, Gu, Wenyi, Papp, Maria, Mookerjee, Raj, Gambino, Carmine Gabriele, Jiménez, Cesar, Giovo, Ilaria, Zaccherini, Giacomo, Merli, Manuela, Putignano, Antonella, Uschner, Frank Erhard, Berg, Thomas, Bruns, Tony, Trautwein, Christian, Zipprich, Alexander, Bañares, Rafael, Presa, José, Genesca, Joan, Vargas, Victor, Fernández, Javier, Bernardi, Mauro, Angeli, Paolo, Jalan, Rajiv, Claria, Joan, Junot, Christophe, Moreau, Richard, Trebicka, Jonel, Arroyo, Vicente

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Tepotinib plus osimertinib in patients with EGFR-mutated non-small-cell lung cancer with MET amplification following progression on first-line osimertinib (INSIGHT 2): a multicentre, open-label, phase 2 trial von Wu, Yi-Long, Guarneri, Valentina, Voon, Pei Jye, Lim, Boon Khaw, Yang, Jin-Ji, Wislez, Marie, Huang, Cheng, Liam, Chong Kin, Mazieres, Julien, Tho, Lye Mun, Hayashi, Hidetoshi, Nhung, Nguyen Viet, Chia, Puey Ling, de Marinis, Filippo, Raskin, Jo, Zhou, Qinghua, Finocchiaro, Giovanna, Le, Anh Tuan, Wang, Jialei, Dooms, Christophe, Kato, Terufumi, Nadal, Ernest, Hin, How Soon, Smit, Egbert F, Wermke, Martin, Tan, Daniel, Morise, Masahiro, O'Brate, Aurora, Adrian, Svenja, Pfeiffer, Boris M, Stroh, Christopher, Juraeva, Dilafruz, Strotmann, Rainer, Goteti, Kosalaram, Berghoff, Karin, Ellers-Lenz, Barbara, Karachaliou, Niki, Le, Xiuning, Kim, Tae Min

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Discovery of Potent and Selective 8‑Fluorotriazolopyridine c‑Met Inhibitors von Peterson, Emily A, Teffera, Yohannes, Albrecht, Brian K, Bauer, David, Bellon, Steven F, Boezio, Alessandro, Boezio, Christiane, Broome, Martin A, Choquette, Deborah, Copeland, Katrina W, Dussault, Isabelle, Lewis, Richard, Lin, Min-Hwa Jasmine, Lohman, Julia, Liu, Jingzhou, Potashman, Michele, Rex, Karen, Shimanovich, Roman, Whittington, Douglas A, Vaida, Karina R, Harmange, Jean-Christophe

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PERSPECTIVE: Tepotinib + cetuximab in patients (pts) with RAS/BRAF wild-type left-sided metastatic colorectal cancer (mCRC) and acquired resistance to anti-EGFR antibody therapy due to MET amplification ( MET amp) von Bekaii-Saab, Tanios S., Van Cutsem, Eric, Cubillo, Antonio, Petorin-Lesens, Caroline, Rodriguez-Salas, Nuria, Raghav, Kanwal Pratap Singh, Dupuis, Olivier, López-López, Carlos, Tournigand, Christophe, Isambert, Nicolas, Abubaker, Khalid, Schumacher, Karl-Maria, Berghoff, Karin, Vlassak, Soetkin, Otto, Gordon, Tabernero, Josep

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iPSC-Derived Embryoid Bodies as Models of c- Met -Mutated Hereditary Papillary Renal Cell Carcinoma von Hwang, Jin Wook, Desterke, Christophe, Féraud, Olivier, Richard, Stephane, Ferlicot, Sophie, Verkarre, Virginie, Patard, Jean Jacques, Loisel-Duwattez, Julien, Foudi, Adlen, Griscelli, Frank, Bennaceur-Griscelli, Annelise, Turhan, Ali G

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MET Is a Potential Target across All Papillary Renal Cell Carcinomas: Result from a Large Molecular Study of pRCC with CGH Array and Matching Gene Expression Array von ALBIGES, Laurence, GUEGAN, Justine, ALLORY, Yves, OREAR, Cedric, COUVE, Sophie, GAD, Sophie, PATARD, Jean-Jacques, ESCUDIER, Bernard, LE FORMAL, Audrey, VERKARRE, Virginie, RIOUX-LECLERCQ, Nathalie, SIBONY, Mathilde, BERNHARD, Jean-Christophe, CAMPARO, Philippe, MERABET, Zahira, MOLINIE, Vincent

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MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis von Cataisson, Christophe, Michalowski, Aleksandra M, Shibuya, Kelly, Ryscavage, Andrew, Klosterman, Mary, Wright, Lisa, Dubois, Wendy, Liu, Fan, Zhuang, Anne, Rodrigues, Kameron B, Hoover, Shelley, Dwyer, Jennifer, Simpson, Mark R, Merlino, Glenn, Yuspa, Stuart H

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Fully automated radiolabeling of [68Ga]Ga-EMP100 targeting c-MET for PET-CT clinical imaging von Rusu, Timofei, Delion, Matthieu, Pirot, Charlotte, Blin, Amaury, Rodenas, Anita, Talbot, Jean-Noël, Veran, Nicolas, Portal, Christophe, Montravers, Françoise, Cadranel, Jacques, Prignon, Aurélie

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Somatic mutations lead to an oncogenic deletion of met in lung cancer von KONG-BELTRAN, Monica, SESHAGIRI, Somasekar, SEVERIN, Christophe, RANGELL, Linda, SCHWALL, Ralph, AMLER, Lukas, WICKRAMASINGHE, Dineli, YAUCH, Robert, JIPING ZHA, WENJING ZHU, BHAWE, Kaumudi, MENDOZA, Nerissa, HOLCOMB, Thomas, PUJARA, Kanan, STINSON, Jeremy, LING FU

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Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET) von Weiss, Emmanuel, de la Pena-Ramirez, Carlos, Aguilar, Ferran, Lozano, Juan-Jose, Sanchez-Garrido, Cristina, Sierra, Patricia, Martin, Pedro Izquierdo-Bueno, Diaz, Juan Manuel, Fenaille, Francois, Castelli, Florence A, Gustot, Thierry, Laleman, Wim, Albillos, Agustin, Alessandria, Carlo, Domenicali, Marco, Caraceni, Paolo, Piano, Salvatore, Saliba, Faouzi, Zeuzem, Stefan, Gerbes, Alexander L, Wendon, Julia A, Jansen, Christian, Gu, Wenyi, Papp, Maria, Mookerjee, Raj, Gambino, Carmine Gabriele, Jimenez, Cesar, Giovo, Ilaria, Zaccherini, Giacomo, Merli, Manuela, Putignano, Antonella, Uschner, Frank Erhard, Berg, Thomas, Bruns, Tony, Trautwein, Christian, Zipprich, Alexander, Banares, Rafael, Presa, Jose, Genesca, Joan, Vargas, Victor, Fernandez, Javier, Bernardi, Mauro, Angeli, Paolo, Jalan, Rajiv, Claria, Joan, Junot, Christophe, Moreau, Richard, Trebicka, Jonel, Arroyo, Vicente

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The impact of resolving the Rossby radius at mid-latitudes in the ocean: results from a high-resolution version of the Met Office GC2 coupled model von Hewitt, Helene T, Roberts, Malcolm J, Hyder, Pat, Graham, Tim, Rae, Jamie, Belcher, Stephen E, Bourdallé-Badie, Romain, Copsey, Dan, Coward, Andrew, Guiavarch, Catherine, Harris, Chris, Hill, Richard, Hirschi, Joël J.-M, Madec, Gurvan, Mizielinski, Matthew S, Neininger, Erica, New, Adrian L, Rioual, Jean-Christophe, Sinha, Bablu, Storkey, David, Shelly, Ann, Thorpe, Livia, Wood, Richard A

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Discovery of (R)‑6-(1-(8-Fluoro-6-(1-methyl‑1H‑pyrazol-4-yl)-[1,2,4]triazolo[4,3‑a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)‑one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity von Boezio, Alessandro A, Copeland, Katrina W, Rex, Karen, K. Albrecht, Brian, Bauer, David, Bellon, Steven F, Boezio, Christiane, Broome, Martin A, Choquette, Deborah, Coxon, Angela, Dussault, Isabelle, Hirai, Satoko, Lewis, Richard, Lin, Min-Hwa Jasmine, Lohman, Julia, Liu, Jingzhou, Peterson, Emily A, Potashman, Michele, Shimanovich, Roman, Teffera, Yohannes, Whittington, Douglas A, Vaida, Karina R, Harmange, Jean-Christophe

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Correction to: Multicenter evaluation of an automated, multiplex, RNA-based molecular assay for detection of ALK, ROS1, RET fusions and MET exon 14 skipping in NSCLC von Melchior, Linea, Hirschmann, Astrid, Hofman, Paul, Bontoux, Christophe, Concha, Angel, Mrabet‑Dahbi, Salima, Vannuffel, Pascal, Watkin, Emmanuel, Putzová, Martina, Scarpino, Stefania, Cayre, Anne, Martin, Paloma, Stoehr, Robert, Hartmann, Arndt

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Four individually druggable MET hotspots mediate HGF-driven tumor progression von Basilico, Cristina, Hultberg, Anna, Blanchetot, Christophe, de Jonge, Natalie, Festjens, Els, Hanssens, Valérie, Osepa, Sjudry-Ilona, De Boeck, Gitte, Mira, Alessia, Cazzanti, Manuela, Morello, Virginia, Dreier, Torsten, Saunders, Michael, de Haard, Hans, Michieli, Paolo

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An improved assay for detection of theranostic gene translocations and MET exon 14 skipping in thoracic oncology von Piton, Nicolas, Lanic, Marie-Delphine, Marguet, Florent, Lamy, Aude, Blanchard, France, Guisier, Florian, Viennot, Mathieu, Salaün, Mathieu, Thiberville, Luc, Jardin, Fabrice, Sabourin, Jean-Christophe, Ruminy, Philippe

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A Constitutional Activating MET Mutation Makes the Genetic Link between Malignancies and Chronic Inflammatory Diseases von El Bouchtaoui, Morad, Do Cruzeiro, Marcio, Leboeuf, Christophe, Loisel-Ferreira, Irmine, Fedronie, Carèle, Ferreira, Chrystophe, Ait El Far, Rachida, Ziol, Marianne, Espié, Marc, Falgarone, Géraldine, Cassinat, Bruno, Kiladjian, Jean-Jacques, Feugeas, Jean-Paul, Janin, Anne, Bousquet, Guilhem

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