AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL von Weisberg, E, Manley, P, Mestan, J, Cowan-Jacob, S, Ray, A, Griffin, J D

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In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants von O'HARE, Thomas, WALTERS, Denise K, DRUKER, Brian J, STOFFREGEN, Eric P, TAIPING JIA, MANLEY, Paul W, MESTAN, Jürgen, COWAN-JACOB, Sandra W, LEE, Francis Y, HEINRICH, Michael C, DEININGER, Michael W. N

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AMN107, a Novel Aminopyrimidine Inhibitor of Bcr-Abl, Has In vitro Activity against Imatinib-Resistant Chronic Myeloid Leukemia von GOLEMOVIC, Mirna, VERSTOVSEK, Srdan, ARLINGHAUS, Ralph B, TONG SUN, KANTARJIAN, Hagop, BERAN, Miloslav, GILES, Francis, CORTES, Jorge, MANSHOURI, Taghi, MANLEY, Paul W, MESTAN, Jürgen, DUGAN, Margaret, ALLAND, Leila, GRIFFIN, James D

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AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity von TRAXLER, Peter, ALLEGRINI, Peter R, MEYER, Thomas, TANG, Careen, WARTMANN, Markus, WOOD, Jeanette, CARAVATTI, Giorgio, BRANDT, Ralf, BRUEGGEN, Josef, COZENS, Robert, FABBRO, Doriano, GROSIOS, Konstantina, LANE, Heidi A, MCSHEEHY, Paul, MESTAN, Jürgen

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Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl von Weisberg, Ellen, Manley, Paul W., Breitenstein, Werner, Brüggen, Josef, Cowan-Jacob, Sandra W., Ray, Arghya, Huntly, Brian, Fabbro, Doriano, Fendrich, Gabriele, Hall-Meyers, Elizabeth, Kung, Andrew L., Mestan, Jürgen, Daley, George Q., Callahan, Linda, Catley, Laurie, Cavazza, Cara, Mohammed, Azam, Neuberg, Donna, Wright, Renee D., Gilliland, D. Gary, Griffin, James D.

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S6K1−/−/S6K2−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kin... von Pende, Mario, Um, Sung Hee, Mieulet, Virginie, Sticker, Melanie, Goss, Valerie L., Mestan, Jurgen, Mueller, Matthias, Fumagalli, Stefano, Kozma, Sara C., Thomas, George

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Allosteric inhibitors of Bcr-abl-dependent cell proliferation von Gray, Nathanael S, Adrián, Francisco J, Ding, Qiang, Sim, Taebo, Velentza, Anastasia, Sloan, Christine, Liu, Yi, Zhang, Guobao, Hur, Wooyoung, Ding, Sheng, Manley, Paul, Mestan, Jürgen, Fabbro, Doriano

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Correction: AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL von Weisberg, E, Manley, P, Mestan, J, Cowan-Jacob, S, Ray, A, Griffin, J D

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In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase von Garcı́a-Echeverrı́a, Carlos, Pearson, Mark A, Marti, Andreas, Meyer, Thomas, Mestan, Juergen, Zimmermann, Johann, Gao, Jiaping, Brueggen, Josef, Capraro, Hans-Georg, Cozens, Robert, Evans, Dean B, Fabbro, Doriano, Furet, Pascal, Porta, Diana Graus, Liebetanz, Janis, Martiny-Baron, Georg, Ruetz, Stephan, Hofmann, Francesco

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Skp2 is Oncogenic and Overexpressed in Human Cancers von Gstaiger, Matthias, Jordan, Richard, Lim, Megan, Catzavelos, Charles, Mestan, Jürgen, Slingerland, Joyce, Krek, Wilhelm

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Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myeloid leukaemia von Manley, Paul William, Cowan-Jacob, Sandra W., Mestan, Jürgen

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PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tum... von WOOD, J. M, BOLD, G, PERSOHN, E, RÖSEL, J, SCHNELL, C, STOVER, D, THEUER, A, TOWBIN, H, WENGER, F, WOODS-COOK, K, MENRAD, A, SIEMEISTER, G, BUCHDUNGER, E, SCHIRNER, M, THIERAUCH, K.-H, SCHNEIDER, M. R, DREVS, J, MARTINY-BARON, G, TOTZKE, F, MARME, D, COZENS, R, FERRARI, S, FREI, J, HOFMANN, F, MESTAN, J, METT, H, O'REILLY, T

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Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin von Wagner, Klaus W, Sapinoso, Lisa M, El-Rifai, Wa'el, Frierson, Henry F, Butz, Nicole, Mestan, Juergen, Hofmann, Francesco, Deveraux, Quinn L, Hampton, Garret M

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Protein kinases as targets for anticancer agents: from inhibitors to useful drugs von Fabbro, Doriano, Ruetz, Stephan, Buchdunger, Elisabeth, Cowan-Jacob, Sandra W, Fendrich, Gabriele, Liebetanz, Janis, Mestan, Jürgen, O'Reilly, Terence, Traxler, Peter, Chaudhuri, Bhabatosh, Fretz, Heinz, Zimmermann, Jürg, Meyer, Thomas, Caravatti, Giorgio, Furet, Pascal, Manley, Paul W

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Tracing pathway activities with kinase inhibitors and reverse phase protein arrays von van Oostrum, Jan, Calonder, Claudio, Rechsteiner, Daniel, Ehrat, Markus, Mestan, Jürgen, Fabbro, Doriano, Voshol, Hans

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New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis von Bold, Guido, Altmann, Karl-Heinz, Frei, Jörg, Lang, Marc, Manley, Paul W, Traxler, Peter, Wietfeld, Bernhard, Brüggen, Josef, Buchdunger, Elisabeth, Cozens, Robert, Ferrari, Stefano, Furet, Pascal, Hofmann, Francesco, Martiny-Baron, Georg, Mestan, Jürgen, Rösel, Johannes, Sills, Matthew, Stover, David, Acemoglu, Figan, Boss, Eugen, Emmenegger, René, Lässer, Laurent, Masso, Elvira, Roth, Rosemarie, Schlachter, Christian, Vetterli, Werner, Wyss, Dominique, Wood, Jeanette M

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Antiviral effects of recombinant tumour necrosis factor in vitro von Mestan, J, Digel, W, Mittnacht, S, Hillen, H, Blohm, D, Möller, A, Jacobsen, H, Kirchner, H

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Anthranilic Acid Amides:  A Novel Class of Antiangiogenic VEGF Receptor Kinase Inhibitors von Manley, Paul W, Furet, Pascal, Bold, Guido, Brüggen, Josef, Mestan, Jürgen, Meyer, Thomas, Schnell, Christian R, Wood, Jeanette, Haberey, Martin, Huth, Andreas, Krüger, Martin, Menrad, Andreas, Ottow, Eckhard, Seidelmann, Dieter, Siemeister, Gerhard, Thierauch, Karl-Heinz

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133 POSTER Discovery of potent and selective focal adhesion kinase inhibitors von Kawahara, E, Miyake, T, Matsuura, N, Umemura, I, Masuya, K, Kanazawa, T, Meyer, T, Mestan, J, Hatakeyama, S, Ohmori, O

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Beta interferon subtype 1 induction by tumor necrosis factor von JACOBSEN, H, MESTAN, J, MITTNACHT, S, DIEFFENBACH, C. W

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