Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer von Sartor, Oliver, de Bono, Johann, Chi, Kim N, Fizazi, Karim, Herrmann, Ken, Rahbar, Kambiz, Tagawa, Scott T, Nordquist, Luke T, Vaishampayan, Nitin, El-Haddad, Ghassan, Park, Chandler H, Beer, Tomasz M, Armour, Alison, Pérez-Contreras, Wendy J, DeSilvio, Michelle, Kpamegan, Euloge, Gericke, Germo, Messmann, Richard A, Morris, Michael J, Krause, Bernd J

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The multifunctional APE1 DNA repair–redox signaling protein as a drug target in human disease von Caston, Rachel A., Gampala, Silpa, Armstrong, Lee, Messmann, Richard A., Fishel, Melissa L., Kelley, Mark R.

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PRECEDENT: A Randomized Phase II Trial Comparing Vintafolide (EC145) and Pegylated Liposomal Doxorubicin (PLD) in Combination Versus PLD Alone in Patients With Platinum-Resistant O... von NAUMANN, R. Wendel, COLEMAN, Robert L, GERSH, Robert H, TENERIELLO, Michael G, HARB, Wael A, KONSTANTINOPOULOS, Panagiotis A, PENSON, Richard T, SYMANOWSKI, James T, LOVEJOY, Chandra D, LEAMON, Christopher P, MORGENSTERN, David E, MESSMANN, Richard A, BURGER, Robert A, SAUSVILLE, Edward A, KUTARSKA, Elzbieta, GHAMANDE, Sharad A, GABRAIL, Nashat Y, DEPASQUALE, Stephen E, NOWARA, Elzbieta, GILBERT, Lucy

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Health-related quality of life and pain outcomes with [177Lu]Lu-PSMA-617 plus standard of care versus standard of care in patients with metastatic castration-resistant prostate can... von Fizazi, Karim, Herrmann, Ken, Krause, Bernd J, Rahbar, Kambiz, Chi, Kim N, Morris, Michael J, Sartor, Oliver, Tagawa, Scott T, Kendi, Ayse T, Vogelzang, Nicholas, Calais, Jeremie, Nagarajah, James, Wei, Xiao X, Koshkin, Vadim S, Beauregard, Jean-Mathieu, Chang, Brian, Ghouse, Ray, DeSilvio, Michelle, Messmann, Richard A, de Bono, Johann

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Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic von Shah, Fenil, Logsdon, Derek, Messmann, Richard A., Fehrenbacher, Jill C., Fishel, Melissa L., Kelley, Mark R.

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Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors von LORUSSO, Patricia M, EDELMAN, Martin J, LEAMON, Christopher P, MESSMANN, Richard A, SAUSVILLE, Edward A, BEVER, Susan L, FORMAN, Karen M, PILAT, Maryjo, QUINN, Mary F, JING LI, HEATH, Elisabeth I, MALBURG, Lisa M, KLEIN, Patrick J

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A phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumors von Tolcher, Anthony W., Rodrigueza, Wendi V., Rasco, Drew W., Patnaik, Amita, Papadopoulos, Kyriakos P., Amaya, Alex, Moore, Timothy D., Gaylor, Shari K., Bisgaier, Charles L., Sooch, Mina P., Woolliscroft, Michael J., Messmann, Richard A.

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Bridging population pharmacokinetic and semimechanistic absorption modeling of APX3330 von Silva, Larissa L., Stratford, Robert E., Messmann, Richard, Kelley, Mark R., Quinney, Sara K.

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Clinical Pharmacokinetics and Exposure-Toxicity Relationship of a Folate-Vinca Alkaloid Conjugate EC145 in Cancer Patients von Li, Jing, Sausville, Edward A., Klein, Patrick J., Morgenstern, David, Leamon, Christopher P., Messmann, Richard A., LoRusso, Patricia

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Multicenter Trial of EC145 in Advanced, Folate-Receptor Positive Adenocarcinoma of the Lung von Edelman, Martin J., Harb, Wael A., Pal, Sridhar E., Boccia, Ralph V., Kraut, Michael J., Bonomi, Philip, Conley, Barbara A., Rogers, John S., Messmann, Richard A., Garon, Edward B.

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Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer von Sartor, Oliver, de Bono, Johann, Chi, Kim N., Fizazi, Karim, Herrmann, Ken, Rahbar, Kambiz, Tagawa, Scott T., Nordquist, Luke T., Vaishampayan, Nitin, El-Haddad, Ghassan, Park, Chandler H., Beer, Tomasz M., Armour, Alison, Pérez-Contreras, Wendy J., DeSilvio, Michelle, Kpamegan, Euloge, Gericke, Germo, Messmann, Richard A., Morris, Michael J., Krause, Bernd J.

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Phase I Trial of 72-Hour Continuous Infusion UCN-01 in Patients With Refractory Neoplasms von SAUSVILLE, Edward A, ARBUCK, Susan G, JING, Xiu-Xian, ROBERGE, Michel, FUSE, Eiichi, KUWABARA, Takashi, SENDEROWICZ, Adrian M, MESSMANN, Richard, HEADLEE, Donna, BAUER, Kenneth S, LUSH, Richard M, MURGO, Anthony, FIGG, William D, LAHUSEN, Tyler, JAKEN, Susan

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Reducing undesirable hepatic clearance of a tumor-targeted vinca alkaloid via novel saccharopeptidic modifications von Leamon, Christopher P, Reddy, Joseph A, Klein, Patrick J, Vlahov, Iontcho R, Dorton, Ryan, Bloomfield, Alicia, Nelson, Melissa, Westrick, Elaine, Parker, Nikki, Bruna, Kristen, Vetzel, Marilynn, Gehrke, Mark, Nicoson, Jeffrey S, Messmann, Richard A, LoRusso, Patricia M, Sausville, Edward A

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Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide von Rodrigueza, Wendi V., Woolliscroft, Michael J., Ebrahim, Abdul-Shukkur, Forgey, Robert, McGovren, Patrick J., Endert, Gerold, Wagner, Andreas, Holewa, Danielle, Aboukameel, Amro, Gill, Richard D., Bisgaier, Charles L., Messmann, Richard A., Whitehead, Christopher E., Izbicka, Elzbieta, Streeper, Robert, Wick, Michael C., Stiegler, Gabriela, Stein, C. A., Monsma, David, Webb, Craig, Sooch, Mina P., Panzner, Steffen, Mohammad, Ramzi, Goodwin, Neal C., Al-Katib, Ayad

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Why We Did What We Did: PSMA PET/CT Selection Criteria for the VISION Trial von Kuo, Phillip H, Benson, Taylor, Messmann, Richard, Groaning, Michael

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Phase I Clinical and Pharmacokinetic Study of Flavopiridol Administered as a Daily 1-Hour Infusion in Patients With Advanced Neoplasms von TAN, Antoinette R, HEADLEE, Donna, SENDEROWICZ, Adrian M, MESSMANN, Richard, SAUSVILLE, Edward A, ARBUCK, Susan G, MURGO, Anthony J, MELILLO, Giovanni, SUOPING ZHAI, FIGG, William D, SWAIN, Sandra M

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Novel first-in-class small molecule targeting APE1/Ref-1 to prevent and treat chemotherapy-induced peripheral neuropathy (CIPN) von Kelley, Mark R., Messmann, Richard Adam, Fehrenbacher, Jill

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Tolerability of [ 177 Lu]Lu-PSMA-617 by treatment exposure in patients with metastatic castration-resistant prostate cancer (mCRPC): A VISION study subgroup analysis von Tagawa, Scott T., Armstrong, Andrew J., Krause, Bernd J., Herrmann, Ken, Rahbar, Kambiz, De Bono, Johann S., Adra, Nabil, Desilvio, Michelle, Messmann, Richard, Holder, Geoffrey, Chi, Kim N.

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Effects of α1-Acid Glycoprotein on the Clinical Pharmacokinetics of 7-Hydroxystaurosporine von SPARREBOOM, Alex, HUACHEN CHEN, FIGG, William D, ACHARYA, Milin R, SENDEROWICZ, Adrian M, MESSMANN, Richard A, KUWABARA, Takashi, VENZON, David J, MURGO, Anthony J, HEADLEE, Donna, SAUSVILLE, Edward A

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Flavopiridol-related Proinflammatory Syndrome Is Associated with Induction of Interleukin-6 von MESSMANN, Richard A, ULLMANN, Claudio Dansky, SENDEROWICZ, Adrian M, LAHUSEN, Tyler, KALEHUA, Audrey, WASFY, Jason, MELILLO, Giovanni, DING, Ivan, HEADLEE, Donna, FIGG, William D, SAUSVILLE, Edward A

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