Anthracycline drug targeting: cytoplasmic versus nuclear – a fork in the road von Lothstein, Leonard, Israel, Mervyn, Sweatman, Trevor W.

Volltext

Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles von Sabnis, Nirupama, Nair, Maya, Israel, Mervyn, McConathy, Walter J, Lacko, Andras G

Volltext

ATM and the Catalytic Subunit of DNA-Dependent Protein Kinase Activate NF-κB through a Common MEK/Extracellular Signal-Regulated Kinase/p90rsk Signaling Pathway in Response to Dist... von Panta, G R, Kaur, S, Cavin, L G, Cortes, M L, Mercurio, F, Lothstein, L, Sweatman, T W, Israel, M, Arsura, M

Volltext

Metabolism and elimination of rhodamine 123 in the rat von SWEATMAN, T. W, SESHADRI, R, ISRAEL, M

Volltext

N-benzyladriamycin-14-valerate (AD 198) activates protein kinase C-δ holoenzyme to trigger mitochondrial depolarization and cytochrome c release independently of permeability trans... von Lothstein, Leonard, Savranskaya, Luydmila, Barrett, Christina M, Israel, Mervyn, Sweatman, Trevor W

Volltext

N-benzyladriamycin-14-valerate (AD 198) activates protein kinase C-?? holoenzyme to trigger mitochondrial depolarization and cytochrome c release independently of permeability tran... von Lothstein, Leonard, Savranskaya, Luydmila, Barrett, Christina M., Israel, Mervyn, Sweatman, Trevor W.

Volltext

Circumvention of Nuclear Factor κB-Induced Chemoresistance by Cytoplasmic-Targeted Anthracyclines von Bilyeu, Jennifer D, Panta, Ganesh R, Cavin, Lakita G, Barrett, Christina M, Turner, Eddie J, Sweatman, Trevor W, Israel, Mervyn, Lothstein, Leonard, Arsura, Marcello

Volltext

Novel extranuclear-targeted anthracyclines override the antiapoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis von Barrett, Christina M, Lewis, Felicia L, Roaten, J Brent, Sweatman, Trevor W, Israel, Mervyn, Cleveland, John L, Lothstein, Leonard

Volltext

Interaction of the novel anthracycline antitumor agent N-benzyladriamycin-14-valerate with the C1-regulatory domain of protein kinase C: structural requirements, isoform specificit... von Roaten, J Brent, Kazanietz, Marcelo G, Caloca, Maria Jose, Bertics, Paul J, Lothstein, Leonard, Parrill, Abby L, Israel, Mervyn, Sweatman, Trevor W

Volltext

ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response t... von Panta, Ganesh R, Kaur, Swayamjot, Cavin, Lakita G, Cortés, Maria L, Mercurio, Frank, Lothstein, Leonard, Sweatman, Trevor W, Israel, Mervyn, Arsura, Marcello

Volltext

Circumvention of Nuclear Factor κB-Induced Chemoresistance by Cytoplasmic-Targeted Anthracyclines von Jennifer D. Bilyeu, Ganesh R. Panta, Lakita G. Cavin, Christina M. Barrett, Eddie J. Turner, Trevor W. Sweatman, Mervyn Israel, Leonard Lothstein, Marcello Arsura

Volltext

Circumvention of nuclear factor kappaB-induced chemoresistance by cytoplasmic-targeted anthracyclines von Bilyeu, Jennifer D, Panta, Ganesh R, Cavin, Lakita G, Barrett, Christina M, Turner, Eddie J, Sweatman, Trevor W, Israel, Mervyn, Lothstein, Leonard, Arsura, Marcello

Volltext

DNA topoisomerase II-mediated interaction of doxorubicin and daunorubicin congeners with DNA von Bodley, A, Liu, L F, Israel, M, Seshadri, R, Koseki, Y, Giuliani, F C, Kirschenbaum, S, Silber, R, Potmesil, M

Volltext

Pilot study of the tolerability and toxicity of intravesical valrubicin immediately after transurethral resection of superficial bladder cancer von Patterson, A.Lynn, Greenberg, Richard E, Weems, Lamar, Bahnson, Robert, Wajsman, Zev, Israel, Mervyn, Sweatman, Trevor, Webber, Denise, Gulfo, Joseph

Volltext

Molecular Models of N-Benzyladriamycin-14-valerate (AD 198) in Complex with the Phorbol Ester-Binding C1b Domain of Protein Kinase C-δ von Roaten, J. Brent, Kazanietz, Marcelo G, Sweatman, Trevor W, Lothstein, Leonard, Israel, Mervyn, Parrill, Abby L

Volltext

Novel Extranuclear-targeted Anthracyclines Override the Antiapoptotic Functions of Bcl-2 and Target Protein Kinase C Pathways to Induce Apoptosis 1 Supported in part by grants from... von Christina M. Barrett, Felicia L. Lewis, J. Brent Roaten, Trevor W. Sweatman, Mervyn Israel, John L. Cleveland, Leonard Lothstein

Volltext

Interaction of the Novel Anthracycline Antitumor Agent N-Benzyladriamycin-14-valerate with the C1-Regulatory Domain of Protein Kinase C: Structural Requirements, Isoform Specificit... von J. Brent Roaten, Marcelo G. Kazanietz, Maria Jose Caloca, Paul J. Bertics, Leonard Lothstein, Abby L. Parrill, Mervyn Israel, Trevor W. Sweatman

Volltext

Initial report on intravesical administration of N-trifluoroacetyladriamycin-14-valerate (AD 32) to patients with refractory superficial transitional cell carcinoma of the urinary... von GREENBERG, R. E, BAHNSON, R. R, GIANTONIO, B, O'DWYER, P. J, WOOD, D, CHILDS, S. J, BELLINGHAM, C, EDSON, M, BAMBERGER, M. H, STEINBERG, G. D, ISRAEL, M, SWEATMAN, T

Volltext

Catalytic inhibition of DNA topoisomerase II by N-benzyladriamycin (AD 288) von Lothstein, Leonard, Suttle, D.Parker, Roaten, J.Brent, Koseki, Yoshihiro, Israel, Mervyn, Sweatman, Trevor W

Volltext

Cytotoxicity and intracellular biotransformation of N-benzyladriamycin-14-yalerate (AD 198) are modulated by changes in 14-O-acyl chain length von Lothstein, Leonard, Rodrigues, Patrick J, Sweatman, Trevor W, Israel, Mervyn

Volltext