SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis von Jacobs, Robert T, Nare, Bakela, Wring, Stephen A, Orr, Matthew D, Chen, Daitao, Sligar, Jessica M, Jenks, Matthew X, Noe, Robert A, Bowling, Tana S, Mercer, Luke T, Rewerts, Cindy, Gaukel, Eric, Owens, Jennifer, Parham, Robin, Randolph, Ryan, Beaudet, Beth, Bacchi, Cyrus J, Yarlett, Nigel, Plattner, Jacob J, Freund, Yvonne, Ding, Charles, Akama, Tsutomu, Zhang, Y-K, Brun, Reto, Kaiser, Marcel, Scandale, Ivan, Don, Robert

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SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis: e1151 von Jacobs, Robert T, Nare, Bakela, Wring, Stephen A, Orr, Matthew D, Chen, Daitao, Sligar, Jessica M, Jenks, Matthew X, Noe, Robert A, Bowling, Tana S, Mercer, Luke T, Rewerts, Cindy, Gaukel, Eric, Owens, Jennifer, Parham, Robin, Randolph, Ryan, Beaudet, Beth, Bacchi, Cyrus J, Yarlett, Nigel, Plattner, Jacob J, Freund, Yvonne, Ding, Charles, Akama, Tsutomu, Zhang, Y-K, Brun, Reto, Kaiser, Marcel, Scandale, Ivan, Don, Robert

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Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing von Anzalone, Andrew V., Gao, Xin D., Podracky, Christopher J., Nelson, Andrew T., Koblan, Luke W., Raguram, Aditya, Levy, Jonathan M., Mercer, Jaron A. M., Liu, David R.

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Examining changes in sexual lifestyles in Britain between 1990-2010: a latent class analysis approach von Muschialli, Luke, Samartsidis, Pantelis, Presanis, Anne M, Mercer, Catherine H

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Lifelong Ulk1-Mediated Autophagy Deficiency in Muscle Induces Mitochondrial Dysfunction and Contractile Weakness von Nichenko, Anna S., Sorensen, Jacob R., Southern, W. Michael, Qualls, Anita E., Schifino, Albino G., McFaline-Figueroa, Jennifer, Blum, Jamie E., Tehrani, Kayvan F., Yin, Hang, Mortensen, Luke J., Thalacker-Mercer, Anna E., Greising, Sarah M., Call, Jarrod A.

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Antidepressant and antipsychotic prescribing in patients with type 2 diabetes in Scotland: A time‐trend analysis from 2004 to 2021 von Greene, Charlotte R. L., Blackbourn, Luke A. K., McGurnaghan, Stuart J., Mercer, Stewart W., Smith, Daniel J., Wild, Sarah H., Wu, Honghan, Jackson, Caroline A.

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Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity von Biswas, Dipsikha, Slade, Logan, Duffley, Luke, Mueller, Neil, Dao, Khoi Thien, Mercer, Angella, Pakkiriswami, Shanmugasundaram, El Hiani, Yassine, Kienesberger, Petra C., Pulinilkunnil, Thomas

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SARS-CoV-2 infection in patients with autoimmune hepatitis von Marjot, Thomas, Buescher, Gustav, Sebode, Marcial, Barnes, Eleanor, Barritt, A. Sidney, Armstrong, Matthew J., Baldelli, Luke, Kennedy, James, Mercer, Carolyn, Ozga, Ann-Kathrin, Casar, Christian, Schramm, Christoph, Moon, Andrew M., Webb, Gwilym J., Lohse, Ansgar W.

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Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice von Nichenko, Anna S., Southern, W. Michael, Tehrani, Kayvan Forouhesh, Qualls, Anita E., Flemington, Alexandra B., Mercer, Grant H., Yin, Amelia, Mortensen, Luke J., Yin, Hang, Call, Jarrod A.

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The effect of intravenous iron supplementation on exercise capacity in iron-deficient but not anaemic patients with chronic kidney disease: study design and baseline data for a mul... von Greenwood, Sharlene A, Beckley-Hoelscher, Nicholas, Asgari, Elham, Ayis, Salma, Baker, Luke A, Banerjee, Debasish, Bhandari, Sunil, Bramham, Kate, Chilcot, Joseph, Burton, James, Kalra, Philip A, Lightfoot, Courtney J, McCafferty, Kieran, Mercer, Thomas H, Okonko, Darlington O, Oliveira, Benjamin, Reid, Chante, Smith, Alice C, Swift, Pauline A, Mangelis, Anastasios, Watson, Emma, Wheeler, David C, Wilkinson, Thomas J, Reid, Fiona, Macdougall, Iain C

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Branched-chain ketoacid overload inhibits insulin action in the muscle von Biswas, Dipsikha, Dao, Khoi T., Mercer, Angella, Cowie, Andrew M., Duffley, Luke, El Hiani, Yassine, Kienesberger, Petra C., Pulinilkunnil, Thomas

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Functional and Evolutionary Characterization of a Gene Transfer Agent's Multilocus "Genome" von Hynes, Alexander P, Shakya, Migun, Mercer, Ryan G, Grüll, Marc P, Bown, Luke, Davidson, Fraser, Steffen, Ekaterina, Matchem, Heidi, Peach, Mandy E, Berger, Tim, Grebe, Katherine, Zhaxybayeva, Olga, Lang, Andrew S

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Protocol for a pragmatic cluster randomised controlled trial assessing the clinical effectiveness and cost-effectiveness of Electronic RIsk-assessment for CAncer for patients in ge... von Hamilton, Willie, Mounce, Luke, Abel, Gary A, Dean, Sarah Gerard, Campbell, John L, Warren, Fiona C, Spencer, Anne, Medina-Lara, Antonieta, Pitt, Martin, Shephard, Elizabeth, Shakespeare, Marijke, Fletcher, Emily, Mercer, Adrian, Calitri, Raff

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Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis von NARE, Bakela, WRING, Stephen, HUSSAIN, Ali, JARNAGIN, Kurt, JENKS, Matthew, KAISER, Marcel, MERCER, Luke, MEJIA, Elena, NOE, Andy, ORR, Matt, PARHAM, Robin, PLATTNER, Jacob, BACCHI, Cyrus, RANDOLPH, Ryan, RATTENDI, Donna, REWERTS, Cindy, SLIGAR, Jessica, YARLETT, Nigel, DON, Robert, JACOBS, Robert, BEAUDET, Beth, BOWLING, Tana, BRUN, Reto, DAITAO CHEN, DING, Charles, FREUND, Yvonne, GAUKEL, Eric

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Unintended pregnancy risk factors and perinatal outcomes in a nulliparous population von Post, Rebecca J., Schmidt, Luke, Crosland, Adam, Chang, Jenny, Ziogas, Argyrios, Silver, Bob M., Parry, Samuel, Saade, George R., Grobman, William A., Mercer, Brian M., Bernard, Caitlin, Simhan, Hyagriv, Chung, Judith H.

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OTH-1 SARS-CoV-2 Infection in patients with autoimmune hepatitis von Marjot, Thomas, Buescher, Gustav, Sebode, Marcial, Barnes, Eleanor, Barritt, Alfred, Armstrong, Matthew, Baldelli, Luke, Kennedy, James, mercer, Carolyn, Ozga, Ann-Kathrin, Casar, Christian, Schramm, Christoph, Moon, Andrew, Webb, Gwilym, Lohse, Ansgar

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Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of... von WRING, STEPHEN, GAUKEL, ERIC, NARE, BAKELA, JACOBS, ROBERT, BEAUDET, BETH, BOWLING, TANA, MERCER, LUKE, BACCHI, CYRUS, YARLETT, NIGEL, RANDOLPH, RYAN, PARHAM, ROBIN, REWERTS, CINDY, PLATNER, JACOB, DON, ROBERT

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Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis von Bowling, Tana, Mercer, Luke, Don, Robert, Jacobs, Robert, Nare, Bakela

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Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT) von Akama, Tsutomu, Zhang, Yong-Kang, Freund, Yvonne R., Berry, Pamela, Lee, Joanne, Easom, Eric E., Jacobs, Robert T., Plattner, Jacob J., Witty, Michael J., Peter, Rosemary, Rowan, Tim G., Gillingwater, Kirsten, Brun, Reto, Nare, Bakela, Mercer, Luke, Xu, Musheng, Wang, Jiangong, Liang, Hao

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A Randomized Trial of Intravenous Iron Supplementation and Exercise on Exercise Capacity in Iron-Deficient Nonanemic Patients With CKD von Greenwood, Sharlene A., Oliveira, Benjamin A., Asgari, Elham, Ayis, Salma, Baker, Luke A., Beckley-Hoelscher, Nicholas, Goubar, Aicha, Banerjee, Debasish, Bhandari, Sunil, Chilcot, Joseph, Burton, James O., Kalra, Philip A., Lightfoot, Courtney J., Macdougall, Iain C., McCafferty, Kieran, Mercer, Thomas H., Okonko, Darlington O., Reid, Chante, Reid, Fiona, Smith, Alice C., Swift, Pauline A., Mangelis, Anastasios, Watson, Emma, Wheeler, David C., Wilkinson, Thomas J., Bramham, Kate

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