Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group von Lobera, Mercedes, Madauss, Kevin P, Pohlhaus, Denise T, Wright, Quentin G, Trocha, Mark, Schmidt, Darby R, Baloglu, Erkan, Trump, Ryan P, Head, Martha S, Hofmann, Glenn A, Murray-Thompson, Monique, Schwartz, Benjamin, Chakravorty, Subhas, Wu, Zining, Mander, Palwinder K, Kruidenier, Laurens, Reid, Robert A, Burkhart, William, Turunen, Brandon J, Rong, James X, Wagner, Craig, Moyer, Mary B, Wells, Carrow, Hong, Xuan, Moore, John T, Williams, Jon D, Soler, Dulce, Ghosh, Shomir, Nolan, Michael A

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Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells von Paul A Wilson, Sara Santos Franco, Liu He, Nicholas W Galwey, Jackie Meakin, Rebecca McIntyre, Simon M McHugh, Michael A Nolan, Sarah L Spain, Thaddeus Carlson, Mercedes Lobera, Justin P Rubio, Bill Davis, Linda C McCarthy

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Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells von Wilson, Paul A, Santos Franco, Sara, He, Liu, Galwey, Nicholas W, Meakin, Jackie, McIntyre, Rebecca, McHugh, Simon M, Nolan, Michael A, Spain, Sarah L, Carlson, Thaddeus, Lobera, Mercedes, Rubio, Justin P, Davis, Bill, McCarthy, Linda C

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Individual intestinal symbionts induce a distinct population of RORγ+regulatory T cells von Sefik, Esen, Geva-Zatorsky, Naama, Oh, Sungwhan, Konnikova, Liza, Zemmour, David, McGuire, Abigail Manson, Burzyn, Dalia, Ortiz-Lopez, Adriana, Lobera, Mercedes, Yang, Jianfei, Ghosh, Shomir, Earl, Ashlee, Snapper, Scott B., Jupp, Ray, Kasper, Dennis, Mathis, Diane, Benoist, Christophe

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Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages von Guerriero, Jennifer L., Sotayo, Alaba, Ponichtera, Holly E., Castrillon, Jessica A., Pourzia, Alexandra L., Schad, Sara, Johnson, Shawn F., Carrasco, Ruben D., Lazo, Suzan, Bronson, Roderick T., Davis, Scott P., Lobera, Mercedes, Nolan, Michael A., Letai, Anthony

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Synthesis of the tetracyclic core of the bisabosquals von Snider, Barry B., Lobera, Mercedes

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Benzofuran Derivatives as Potent, Orally Active S1P1 Receptor Agonists: A Preclinical Lead Molecule for MS von Saha, Ashis K, Yu, Xiang, Lin, Jian, Lobera, Mercedes, Sharadendu, Anurag, Chereku, Srinivas, Schutz, Nili, Segal, Dalia, Marantz, Yael, McCauley, Dilara, Middleton, Scot, Siu, Jerry, Bürli, Roland W, Buys, Janet, Horner, Michelle, Salyers, Kevin, Schrag, Michael, Vargas, Hugo M, Xu, Yang, McElvain, Michele, Xu, Han

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Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo von Skepner, Jill, Ramesh, Radha, Trocha, Mark, Schmidt, Darby, Baloglu, Erkan, Lobera, Mercedes, Carlson, Thaddeus, Hill, Jonathan, Orband-Miller, Lisa A, Barnes, Ashley, Boudjelal, Mohamed, Sundrud, Mark, Ghosh, Shomir, Yang, Jianfei

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Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms von Xiao, Sheng, Yosef, Nir, Yang, Jianfei, Wang, Yonghui, Zhou, Ling, Zhu, Chen, Wu, Chuan, Baloglu, Erkan, Schmidt, Darby, Ramesh, Radha, Lobera, Mercedes, Sundrud, Mark S., Tsai, Pei-Yun, Xiang, Zhijun, Wang, Jinsong, Xu, Yan, Lin, Xichen, Kretschmer, Karsten, Rahl, Peter B., Young, Richard A., Zhong, Zhong, Hafler, David A., Regev, Aviv, Ghosh, Shomir, Marson, Alexander, Kuchroo, Vijay K.

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TMP778, a selective inhibitor of RORγt, suppresses experimental autoimmune uveitis development, but affects both Th17 and Th1 cell populations von Lyu, Cancan, Bing, So Jin, Wandu, Wambui S., Xu, Biying, Shi, Guangpu, Hinshaw, Samuel J., Lobera, Mercedes, Caspi, Rachel R., Lu, Lin, Yang, Jianfei, Gery, Igal

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From RORγt Agonist to Two Types of RORγt Inverse Agonists von Wang, Yonghui, Cai, Wei, Tang, Ting, Liu, Qian, Yang, Ting, Yang, Liuqing, Ma, Yingli, Zhang, Guifeng, Huang, Yafei, Song, Xiaoxia, Orband-Miller, Lisa A, Wu, Qianqian, Zhou, Ling, Xiang, Zhijun, Xiang, Jia-Ning, Leung, Stewart, Shao, Liming, Lin, Xichen, Lobera, Mercedes, Ren, Feng

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Class IIa HDAC inhibition reduces breast tumors and metastases via anti-tumor macrophages von Guerriero, Jennifer L., Sotayo, Alaba, Ponichtera, Holly E., Castrillon, Jessica A., Pourzia, Alexandra L., Schad, Sara, Johnson, Shawn F., Carrasco, Ruben D., Lazo, Suzan, Bronson, Roderick T., Davis, Scott P., Lobera, Mercedes, Nolan, Michael A., Letai, Anthony

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In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists von Skepner, Jill, Trocha, Mark, Ramesh, Radha, Qu, Xiaoyan A., Schmidt, Darby, Baloglu, Erkan, Lobera, Mercedes, Davis, Scott, Nolan, Michael A., Carlson, Thaddeus J., Hill, Jonathan, Ghosh, Shomir, Sundrud, Mark S., Yang, Jianfei

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An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition von Forcade, Edouard, Paz, Katelyn, Flynn, Ryan, Griesenauer, Brad, Amet, Tohti, Li, Wei, Liu, Liangyi, Bakoyannis, Giorgos, Jiang, Di, Chu, Hong Wei, Lobera, Mercedes, Yang, Jianfei, Wilkes, David S, Du, Jing, Gartlan, Kate, Hill, Geoffrey R, MacDonald, Kelli Pa, Espada, Eduardo L, Blanco, Patrick, Serody, Jonathan S, Koreth, John, Cutler, Corey S, Antin, Joseph H, Soiffer, Robert J, Ritz, Jerome, Paczesny, Sophie, Blazar, Bruce R

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Individual intestinal symbionts induce a distinct population of ROR[gamma]+ regulatory T cells von Esen Sefik, Geva-Zatorsky, Naama, Oh, Sungwhan, Konnikova, Liza, Zemmour, David, Abigail Manson McGuire, Burzyn, Dalia, Ortiz-Lopez, Adriana, Lobera, Mercedes, Yang, Jianfei, Ghosh, Shomir, Earl, Ashlee, Snapper, Scott B, Jupp, Ray, Kasper, Dennis, Mathis, Diane

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Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo (THER6P.855) von Yang, Jianfei, Skepner, Jill, Ramesh, Radha, Trocha, Mark, Schmidt, Darby, Baloglu, Erkan, Lobera, Mercedes, Carlson, Thaddeus, Hill, Jonathan, Miller, Lias, Barnes, Ashley, Boudjelal, Mohamed, Sundrud, Mark, Ghosh, Shomir

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Abstract B35: Class IIa HDAC inhibition promotes an antitumor macrophage phenotype that induces breast tumor regression and inhibits metastasis von Guerriero, Jennifer L., Sotayo, Alaba, Ponichtera, Holly E., Castrillon, Jessica A., Pourzia, Alexandra L., Schad, Sara, Johnson, Shawn F., Carrasco, Ruben D., Lazo, Susan B., Bronson, Roderick T., Davis, Scott P., Lobera, Mercedes X., Nolan, Michael A., Letai, Anthony

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In vivo regulation of gene expression and T helper type 17 differentiation by ROR[gamma]t inverse agonists von Skepner, Jill, Trocha, Mark, Ramesh, Radha, Qu, Xiaoyan A, Schmidt, Darby, Baloglu, Erkan, Lobera, Mercedes, Davis, Scott, Nolan, Michael A, Carlson, Thaddeus J, Hill, Jonathan, Ghosh, Shomir, Sundrud, Mark S, Yang, Jianfei

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Synthesis of 2,3-Dihydro-3-hydroxy-2-hydroxylalkylbenzofurans from Epoxy Aldehydes. One-Step Syntheses of Brosimacutin G, Vaginidiol, Vaginol, Smyrindiol, Xanthoarnol, and Avicenol... von Zou, Yefen, Lobera, Mercedes, Snider, Barry B

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Small-Molecule ROR[gamma]t Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms von Xiao, Sheng, Yosef, Nir, Yang, Jianfei, Wang, Yonghui, Zhou, Ling, Zhu, Chen, Wu, Chuan, Baloglu, Erkan, Schmidt, Darby, Ramesh, Radha, Lobera, Mercedes, Sundrud, Mark S, Tsai, Pei-Yun, Xiang, Zhijun, Wang, Jinsong, Xu, Yan, Lin, Xichen, Kretschmer, Karsten, Rahl, Peter B, Young, Richard A, Zhong, Zhong, Hafler, David A, Regev, Aviv, Ghosh, Shomir, Marson, Alexander, Kuchroo, Vijay K

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