Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer von Scales, Michael K, Velez-Delgado, Ashley, Steele, Nina G, Schrader, Hannah E, Stabnick, Anna M, Yan, Wei, Mercado Soto, Nayanna M, Nwosu, Zeribe C, Johnson, Craig, Zhang, Yaqing, Salas-Escabillas, Daniel J, Menjivar, Rosa E, Maurer, H Carlo, Crawford, Howard C, Bednar, Filip, Olive, Kenneth P, Pasca di Magliano, Marina, Allen, Benjamin L

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Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1 von Kemp, Samantha B, Carpenter, Eileen S, Steele, Nina G, Donahue, Katelyn L, Nwosu, Zeribe C, Pacheco, Amanda, Velez-Delgado, Ashley, Menjivar, Rosa E, Lima, Fatima, The, Stephanie, Espinoza, Carlos E, Brown, Kristee, Long, Daniel, Lyssiotis, Costas A, Rao, Arvind, Zhang, Yaqing, Pasca di Magliano, Marina, Crawford, Howard C

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Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis von Zhang, Yaqing, Lazarus, Jenny, Steele, Nina G, Yan, Wei, Lee, Ho-Joon, Nwosu, Zeribe C, Halbrook, Christopher J, Menjivar, Rosa E, Kemp, Samantha B, Sirihorachai, Veerin R, Velez-Delgado, Ashley, Donahue, Katelyn, Carpenter, Eileen S, Brown, Kristee L, Irizarry-Negron, Valerie, Nevison, Anna C, Vinta, Alekya, Anderson, Michelle A, Crawford, Howard C, Lyssiotis, Costas A, Frankel, Timothy L, Bednar, Filip, Pasca di Magliano, Marina

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Arginase 1 is a key driver of immune suppression in pancreatic cancer von Menjivar, Rosa E, Nwosu, Zeribe C, Du, Wenting, Donahue, Katelyn L, Hong, Hanna S, Espinoza, Carlos, Brown, Kristee, Velez-Delgado, Ashley, Yan, Wei, Lima, Fatima, Bischoff, Allison, Kadiyala, Padma, Salas-Escabillas, Daniel, Crawford, Howard C, Bednar, Filip, Carpenter, Eileen, Zhang, Yaqing, Halbrook, Christopher J, Lyssiotis, Costas A, Pasca di Magliano, Marina

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WNT signaling in the tumor microenvironment promotes immunosuppression in murine pancreatic cancer von Du, Wenting, Menjivar, Rosa E, Donahue, Katelyn L, Kadiyala, Padma, Velez-Delgado, Ashley, Brown, Kristee L, Watkoske, Hannah R, He, Xi, Carpenter, Eileen S, Angeles, Christina V, Zhang, Yaqing, Pasca di Magliano, Marina

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Uridine-derived ribose fuels glucose-restricted pancreatic cancer von Nwosu, Zeribe C., Ward, Matthew H., Sajjakulnukit, Peter, Poudel, Pawan, Ragulan, Chanthirika, Kasperek, Steven, Radyk, Megan, Sutton, Damien, Menjivar, Rosa E., Andren, Anthony, Apiz-Saab, Juan J., Tolstyka, Zachary, Brown, Kristee, Lee, Ho-Joon, Dzierozynski, Lindsey N., He, Xi, PS, Hari, Ugras, Julia, Nyamundanda, Gift, Zhang, Li, Halbrook, Christopher J., Carpenter, Eileen S., Shi, Jiaqi, Shriver, Leah P., Patti, Gary J., Muir, Alexander, Pasca di Magliano, Marina, Sadanandam, Anguraj, Lyssiotis, Costas A.

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Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming von Velez-Delgado, Ashley, Donahue, Katelyn L., Brown, Kristee L., Du, Wenting, Irizarry-Negron, Valerie, Menjivar, Rosa E., Lasse Opsahl, Emily L., Steele, Nina G., The, Stephanie, Lazarus, Jenny, Sirihorachai, Veerin R., Yan, Wei, Kemp, Samantha B., Kerk, Samuel A., Bollampally, Murali, Yang, Sion, Scales, Michael K., Avritt, Faith R., Lima, Fatima, Lyssiotis, Costas A., Rao, Arvind, Crawford, Howard C., Bednar, Filip, Frankel, Timothy L., Allen, Benjamin L., Zhang, Yaqing, Pasca di Magliano, Marina

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Tumor-associated macrophages restrict CD8 + T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment von Tharp, Kevin M, Kersten, Kelly, Maller, Ori, Timblin, Greg A, Stashko, Connor, Canale, Fernando P, Menjivar, Rosa E, Hayward, Mary-Kate, Berestjuk, Ilona, Ten Hoeve, Johanna, Samad, Bushra, Ironside, Alastrair J, di Magliano, Marina Pasca, Muir, Alexander, Geiger, Roger, Combes, Alexis J, Weaver, Valerie M

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Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis von Apiz Saab, Juan J, Dzierozynski, Lindsey N, Jonker, Patrick B, AminiTabrizi, Roya, Shah, Hardik, Menjivar, Rosa Elena, Scott, Andrew J, Nwosu, Zeribe C, Zhu, Zhou, Chen, Riona N, Oh, Moses, Sheehan, Colin, Wahl, Daniel R, Pasca di Magliano, Marina, Lyssiotis, Costas A, Macleod, Kay F, Weber, Christopher R, Muir, Alexander

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Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2) von Shen, Yu-Chi, Arellano-Garcia, Caroline, Menjivar, Rosa E, Jewett, Ethan M, Dohle, Wolfgang, Karchugina, Sofiia, Chernoff, Jonathan, Potter, Barry V L, Barald, Kate F

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A genome-wide immunodetection screen in S. cerevisiae uncovers novel genes involved in lysosomal vacuole function and morphology von Ricarte, Florante, Menjivar, Rosa, Chhun, Surya, Soreta, Tattika, Oliveira, Lisa, Hsueh, Teli, Serranilla, Maribeth, Gharakhanian, Editte

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Abstract PO-104: Activation of WNT signaling in CD4+ T cells promotes immune suppression in pancreatic cancer von Du, Wenting, Menjivar, Rosa E., Donahue, Katelyn, Velez-Delgado, Ashley, Pasca di Magliano, Marina

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Abstract A58: Notch signaling is a key regulator for immune-suppressive function of tumor-associated macrophages in pancreatic adenocarcinoma von Yan, Wei, Zhang, Yaqing, Menjivar, Rosa, Bednar, Filip, Magliano, Marina Pasca di, Burns, William Reece

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Abstract PR13: Macrophage metabolism inhibits pancreatic cancer therapy von Halbrook, Christopher J., Menjivar, Rosa, Thurston, Galloway, Magliano, Marina Pasca di, Lyssiotis, Costas

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Abstract PO-116: Deletion of Arginase 1 in myeloid cells alters the pancreatic cancer microenvironment von Menjivar, Rosa E., Nwosu, Zeribe, Du, Wenting, Donahue, Katelyn, Espinoza, Carlos, Velez-Delgado, Ashley, Brown, Kristee, Yan, Wei, Halbrook, Christopher, Zhang, Yaqing, Lyssiotis, Costas, Pasca di Magliano, Marina

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Abstract A54: Oncogenic Kras modulates pancreas plasticity and the tumor microenvironment von Velez-Delgado, Ashley, Irizarry-Negron, Valerie, Menjivar, Rosa, Lazarus, Jenny, Bollampally, Murali, Steele, Nina, Frankel, Timothy, Bednar, Fillip, Zhang, Yaqing, Magliano, Marina Pasca di

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Abstract A31: Investigating the effect of myeloid Arg1 deletion on tumor growth and CD8+ T-cell infiltration and activation in pancreatic cancer von Menjivar, Rosa E., Halbrook, Christopher, Velez, Ashley, Lima, Fatima, Espinoza, Carlos, Galban, Stefanie, Zhang, Yaqing, Lyssiotis, Costas, Magliano, Marina Pasca di

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Abstract PR-016: Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming von Velez-Delgado, Ashley, Donahue, Katelyn L., Brown, Kristee L., Du, Wenting, Irizarry-Negron, Valerie, Menjivar, Rosa E., Lasse-Opsahl, Emily L., Steele, Nina G., The, Stephanie, Lazarus, Jenny, Sirihorachai, Veerin R., Bednar, Filip, Frankel, Timothy L., Zhang, Yaqing, Pasca di Magliano, Marina

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Abstract I04: Regulatory T-cell depletion causes compensatory immune suppression and accelerates pancreatic carcinogenesis von Zhang, Yaqing, Lazarus, Jenny, Steele, Nina, Lee, Ho-Joon, Yan, Wei, Halbrook, Cristopher J., Menjivar, Rosa, Kemp, Samantha B., Sirihoracai, Veerin, Carpenter, Eileen S., Nevison, Anna C., Vinta, Alekya, Anderson, Michelle A., Crawford, Howard C., Lyssiotis, Costas A., Frankel, Timothy L., Bednar, Filip, Magliano, Marina Pasca di

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Abstract A62: Regulatory T-cell depletion promotes oncogenic Kras-driven pancreatic carcinogenesis von Zhang, Yaqing, Lazarus, Jenny, Steele, Nina, Yan, Wei, Lee, Ho-Joon, Halbrook, Christopher J., Menjivar, Rosa, Kemp, Samantha B., Sirihorachai, Veerin, Carpenter, Eileen S., Nevison, Anna C., Vinta, Alekya, Anderson, Michelle A., Crawford, Howard C., Lyssiotis, Costas A., Frankel, Timothy L., Bednar, Filip, Magliano, Marina Pasca di

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