Pneumococcal Conjugate Vaccine Does Not Induce Humoral Response When Administrated Within the Six Months After CD19 CAR T-Cell Therapy von Lee, Dasom, Jordan, Aryanna I, Menges, Meghan A., Lazaryan, Aleksandr, Nishihori, Taiga, Gaballa, Sameh R., Shah, Bijal D, Pinilla-Ibarz, Javier, Baluch, Aliyah, Klinkova, Olga V., Chavez, Julio C., Jain, Michael D., Locke, Frederick L.

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Metabolically Flexible CAR T Cells (mfCAR-T), with Constitutive Expression of PGC-1α Resistant to Post Translational Modifications, Exhibit Superior Survival and Function in Vitro von Atkins, Reginald M, Menges, Meghan A, Bauer, Alexis, Turner, Joel G., Locke, Frederick L.

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Concurrent Monitoring of Peripheral Blood Circulating Tumor DNA and Circulating Tumor Cells in Relapsed/Refractory Follicular Lymphoma Patients Post Axicabtagene Ciloleucel, a Sing... von Gaballa, Sameh, Chavez, Julio C., Jain, Michael D., Menges, Meghan A, Reid, Kayla M, Kaldas, David, Shah, Bijal D., Davila, Marco L., Locke, Frederick L.

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Interim Results of a Prospective Trial Testing Vaccination Against Pneumococcus before and after CD19 CAR T Cell Therapy to Optimize Humoral Immunity von Lee, Dasom, Babu, Abida Poovathukaran, Corallo, Salvatore A., Menges, Meghan A., Hidalgo-Vargas, Melanie J., Ames, Danielle M., Lazaryan, Aleksandr, Nishihori, Taiga, Khimani, Farhad, Gaballa, Sameh, Shah, Bijal D., Pinilla Ibarz, Javier, Chavez, Julio C., Jain, Michael D., Locke, Frederick L.

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High Metabolic Tumor Volume Is Associated with Higher Toxicity and Decreased Efficacy of BCMA CAR-T Cell Therapy in Multiple Myeloma von Villanueva, Ricardo, Hansen, Doris K., Tonseth, Rolf Petter, Gage, Kenneth L, Wei, Zhouping, De Avila, Gabriel, Baz, Rachid C., Grajales-Cruz, Ariel F, Castaneda-Puglianini, Omar, Blue, Brandon J., Brayer, Jason, Shain, Kenneth H., Alsina, Melissa, Liu, Hien D., Nishihori, Taiga, Menges, Meghan A, Locke, Frederick L., Balagurunathan, Yoganand, Freeman, Ciara L.

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Baseline CRP and Ferritin Identify Patients at High Risk of Poor Outcomes after Axicabtagene Ciloleucel Despite Corticosteroid Prophylaxis von Faramand, Rawan, Jain, Michael D., Cao, Biwei, Wang, Xuefeng, Reid, Kayla M., Lee, Sae Bom, Corallo, Salvatore A., Menges, Meghan A., Hidalgo-Vargas, Melanie, Bachmeier, Christina A., Chavez, Julio C., Shah, Bijal D., Pinilla Ibarz, Javier, Lazaryan, Aleksandr, Khimani, Farhad, Nishihori, Taiga, Speth, Kelly, Song, Qinghua, Mattie, Mike, Locke, Frederick L., Davila, Marco L.

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Tumor Inflammation and Myeloid Derived Suppressor Cells Reduce the Efficacy of CD19 CAR T Cell Therapy in Lymphoma von Jain, Michael D., Zhao, Hua, Atkins, Reginald, Menges, Meghan A, Pope, Crystal R, Faramand, Rawan, Lee, Sae Bom, Boucher, Justin C., Kotani, Hiroshi, Bachmeier, Christina A, Chavez, Julio, Shah, Bijal, Hussaini, Mohammad, Gonzalez, Ricardo J, Mullinax, John E, Davila, Marco L., Locke, Frederick L.

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Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma von Jain, Michael D., Zhao, Hua, Wang, Xuefeng, Atkins, Reginald, Menges, Meghan, Reid, Kayla, Spitler, Kristen, Faramand, Rawan, Bachmeier, Christina, Dean, Erin A., Cao, Biwei, Chavez, Julio C., Shah, Bijal, Lazaryan, Aleksandr, Nishihori, Taiga, Hussaini, Mohammed, Gonzalez, Ricardo J., Mullinax, John E., Rodriguez, Paulo C., Conejo-Garcia, Jose R., Anasetti, Claudio, Davila, Marco L., Locke, Frederick L.

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CAR-T manufactured from frozen PBMC yield efficient function with prolonged in vitro production von Abraham-Miranda, Julieta, Menges, Meghan, Atkins, Reginald, Mattie, Mike, Kanska, Justyna, Turner, Joel, Hidalgo-Vargas, Melanie J., Locke, Frederick L.

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Whole-genome sequencing reveals complex genomic features underlying anti-CD19 CAR T-cell treatment failures in lymphoma von Jain, Michael D., Ziccheddu, Bachisio, Coughlin, Caroline A., Faramand, Rawan, Griswold, Anthony J., Reid, Kayla M., Menges, Meghan, Zhang, Yonghong, Cen, Ling, Wang, Xuefeng, Hussaini, Mohammad, Landgren, Ola, Davila, Marco L., Schatz, Jonathan H., Locke, Frederick L., Maura, Francesco

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A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy von Stein-Thoeringer, Christoph K., Saini, Neeraj Y., Zamir, Eli, Blumenberg, Viktoria, Schubert, Maria-Luisa, Mor, Uria, Fante, Matthias A., Schmidt, Sabine, Hayase, Eiko, Hayase, Tomo, Rohrbach, Roman, Chang, Chia-Chi, McDaniel, Lauren, Flores, Ivonne, Gaiser, Rogier, Edinger, Matthias, Wolff, Daniel, Heidenreich, Martin, Strati, Paolo, Nair, Ranjit, Chihara, Dai, Fayad, Luis E., Ahmed, Sairah, Iyer, Swaminathan P., Steiner, Raphael E., Jain, Preetesh, Nastoupil, Loretta J., Westin, Jason, Arora, Reetakshi, Wang, Michael L., Turner, Joel, Menges, Meghan, Hidalgo-Vargas, Melanie, Reid, Kayla, Dreger, Peter, Schmitt, Anita, Müller-Tidow, Carsten, Locke, Frederick L., Davila, Marco L., Champlin, Richard E., Flowers, Christopher R., Shpall, Elizabeth J., Poeck, Hendrik, Neelapu, Sattva S., Schmitt, Michael, Subklewe, Marion, Jain, Michael D., Jenq, Robert R., Elinav, Eran

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The relative contribution of calcium, zinc and oxidation-based cross-links to the stiffness of Arion subfuscus glue von Braun, M, Menges, M, Opoku, F, Smith, A M

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Clinical Impact of Neoantigen Burden and HLA Loss in Aggressive B-Cell Lymphomas Treated with CD19 CAR T-Cell von Ziccheddu, Bachisio, Jain, Michael D., Chojnacka, Monika, Durante, Michael, Abraham Miranda, Julieta, Menges, Meghan, Landgren, Ola, Davila, Marco, Schatz, Jonathan H., Maura, Francesco, Locke, Frederick L.

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CD19 Intron Retention Is Mechanism of CAR-T Treatment Resistance in Non-Hodgkin Lymphoma von Noble, Jerald, Locke, Frederick L., Savid-Frontera, Constanza, Jain, Michael D., Turner, Joel G., Abraham Miranda, Julieta, Madanayake, Thushara W, Naderinezhad, Samira, Corallo, Salvatore, Menges, Meghan, Reid, Kayla, Robinson, Timothy J

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Survivin Dendritic Cell Vaccine Safely Induces Immune Responses and Is Associated with Durable Disease Control after Autologous Transplant in Patients with Myeloma von Freeman, Ciara L, Atkins, Reginald, Varadarajan, Indumathy, Menges, Meghan, Edelman, Jeffrey, Baz, Rachid, Brayer, Jason, Castaneda Puglianini, Omar, Ochoa-Bayona, Jose Leonel, Nishihori, Taiga, Shain, Kenneth H, Shah, Bijal, Chen, Dung Tsa, Kelley, Linda, Coppola, Domenico, Alsina, Melissa, Antonia, Scott, Anasetti, Claudio, Locke, Frederick L

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Expression of Cell Surface Immunotherapy Targets across the Multiple Myeloma Disease Spectrum: Implications for Sequencing and Multi-Target Strategies von Freeman, Ciara Louise L., Menges, Meghan, Noble, Jerald, Alugubelli, Raghunandan Reddy, Renatino-Canevarolo, Rafael, Hampton, Oliver, Sudalagunta, Praneeth Reddy, Corallo, Salvatore, Siqueira Silva, Ariosto, Meads, Mark B, Baz, Rachid, Alsina, Melissa, Hansen, Doris K., Nishihori, Taiga, Castaneda, Omar, Blue, Brandon, Grajales-Cruz, Ariel F., Wang, Yunfei, Hwu, Patrick, Koomen, John, Shain, Kenneth H., Locke, Frederick L.

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Poor Hematopoietic Reserve at the Time of CD19 CAR T-Cell Infusion Is Associated with Long Term B-Cell Aplasia von Johnson, Grace, Patel, Kedar, Arciola, Brian, Perez Perez, Ariel, Wood, Anthony, Ionescu, Filip, Logue, Jennifer M, Albanyan, Omar, Yasin, Hassaan, Bachmeier, Christina A, Reid, Kayla, Menges, Meghan, Corallo, Salvatore, Shah, Bijal D., Chavez, Julio C, Khimani, Farhad, Nishihori, Taiga, Faramand, Rawan, Liu, Hien, Lazaryan, Aleksandr, Rejeski, Kai, Subklewe, Marion, Perna, Fabiana, Davila, Marco, Mhaskar, Rahul, Locke, Frederick L., Jain, Michael D.

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CAR-T Phenotype and Efficacy Is Impaired By Lymphoma-Associated CD39 + T Cells von Jain, Michael D., Yu, Xiaoqing, Atkins, Reginald, Turner, Joel G., Noble, Jerald, Menges, Meghan, Reid, Kayla, Corallo, Salvatore, Cen, Ling, Yoder, Sean J., Abraham Miranda, Julieta, Naderinezhad, Samira, Liu, Hien, Shah, Bijal D., Chavez, Julio C, Dean, Erin, Fahrmann, Johannes, Saini, Neeraj Y., Hanash, Samir, Hesterberg, Rebecca S., Rodriguez, Paulo C., Cleveland, John L., Davila, Marco, Wang, Xuefeng, Locke, Frederick L.

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Paired Analysis from Patients with Myeloma Elucidates Favorable CAR-T Manufacture and Phenotype, Starting from Mobilized Pre-Transplant Apheresis Vs. Non-Mobilized Apheresis after... von Freeman, Ciara Louise L., Abraham Miranda, Julieta, Menges, Meghan, Noble, Jerald, Liu, Hien, Corallo, Salvatore, Ribickas, Albert J, Savid-Frontera, Constanza, De Avila, Gabriel, Castaneda, Omar, Ochoa-Bayona, Jose L., Baz, Rachid, Hansen, Doris K., Alsina, Melissa, Shain, Kenneth H., Nishihori, Taiga, Atkins, Reginald, Locke, Frederick L.

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Cladribine and Cyclophosphamide Lymphodepletion Prior to Axicabtagene Ciloleucel in Relapsed or Refractory Large B-Cell Lymphoma von Ionescu, Filip, Shah, Bijal D., Menges, Meghan, Reid, Kayla, Bailey, Hanna, DiMaggio, Elizabeth, Gonzalez, Rebecca, Bachmeier, Christina A, Corallo, Salvatore, Cuadrado Delgado, Luis, Mohammed, Turab, Nishihori, Taiga, Khimani, Farhad, Lazaryan, Aleksandr, Liu, Hien, Davila, Marco, Perna, Fabiana, Chavez, Julio C, Locke, Frederick L., Jain, Michael D.

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