The Interplay Between the Genetic and Immune Landscapes of AML: Mechanisms and Implications for Risk Stratification and Therapy von Mendez, Lourdes M., Posey, Ryan R., Pandolfi, Pier Paolo

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Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas von Ding, B. Belinda, Yu, J. Jessica, Yu, Raymond Y.-L., Mendez, Lourdes M., Shaknovich, Rita, Zhang, Yonghui, Cattoretti, Giorgio, Ye, B. Hilda

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Clonal Hematopoiesis: Origins and determinants of evolution von Mendez, Lourdes M., Patnaik, Mrinal M.

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Therapeutic Potential of Targeting the SUMO Pathway in Cancer von Kukkula, Antti, Ojala, Veera K., Mendez, Lourdes M., Sistonen, Lea, Elenius, Klaus, Sundvall, Maria

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Circulating Protein Disulfide Isomerase Is Associated with Increased Risk of Thrombosis in JAK2-Mutated Myeloproliferative Neoplasms von Sharda, Anish, Bogue, Thomas, Barr, Alexandra, Mendez, Lourdes M., Flaumenhaft, Robert, Zwicker, Jeffrey

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CtBP Is an Essential Corepressor for BCL6 Autoregulation von Mendez, Lourdes M., Polo, Jose M., Yu, J. Jessica, Krupski, Melissa, Ding, B. Belinda, Melnick, Ari, Ye, B. Hilda

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Germline NPM1 mutations lead to altered rRNA 2′-O-methylation and cause dyskeratosis congenita von Nachmani, Daphna, Bothmer, Anne H., Grisendi, Silvia, Mele, Aldo, Bothmer, Dietmar, Lee, Jonathan D., Monteleone, Emanuele, Cheng, Ke, Zhang, Yang, Bester, Assaf C., Guzzetti, Alison, Mitchell, Caitlin A., Mendez, Lourdes M., Pozdnyakova, Olga, Sportoletti, Paolo, Martelli, Maria-Paola, Vulliamy, Tom J., Safra, Modi, Schwartz, Schraga, Luzzatto, Lucio, Bluteau, Olivier, Soulier, Jean, Darnell, Robert B., Falini, Brunangelo, Dokal, Inderjeet, Ito, Keisuke, Clohessy, John G., Pandolfi, Pier Paolo

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Ipilimumab plus decitabine for patients with MDS or AML in posttransplant or transplant-naïve settings von Garcia, Jacqueline S., Flamand, Yael, Penter, Livius, Keng, Michael, Tomlinson, Benjamin K., Mendez, Lourdes M., Koller, Paul, Cullen, Nicole, Arihara, Yohei, Pfaff, Kathleen, Wolff, Jacquelyn O., Brunner, Andrew M., Galinsky, Ilene, Bashey, Asad, Antin, Joseph H., Cutler, Corey, Ho, Vincent, Jonas, Brian A., Luskin, Marlise R., Wadleigh, Martha, Winer, Eric S., Savell, Alexandra, Leonard, Rebecca, Robertson, Taylor, Davids, Matthew S., Streicher, Howard, Rodig, Scott J., Ritz, Jerome, Wu, Catherine J., DeAngelo, Daniel J., Neuberg, Donna, Stone, Richard M., Soiffer, Robert J.

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VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2 von Sharda, Anish V., Barr, Alexandra M., Harrison, Joshua A., Wilkie, Adrian R., Fang, Chao, Mendez, Lourdes M., Ghiran, Ionita C., Italiano, Joseph E., Flaumenhaft, Robert

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Clonal cytopenia of undetermined significance: definitions, risk and therapeutic targets von Taborda, Cristian C., Zeidan, Amer M., Mendez, Lourdes M.

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Older patients with chronic myeloid leukemia face suboptimal molecular testing and tyrosine kinase inhibitor adherence von Shallis, Rory M., Wang, Rong, Zeidan, Amer M., Huntington, Scott F., Neparidze, Natalia, Stempel, Jessica M., Mendez, Lourdes M., Di, Mengyang, Ma, Xiaomei, Podoltsev, Nikolai A.

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Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial von Brunner, Andrew M, Blonquist, Traci M, DeAngelo, Daniel J, McMasters, Malgorzata, Fell, Geoffrey, Hermance, Nicole M, Winer, Eric S, Lindsley, R Coleman, Hobbs, Gabriela S, Amrein, Philip C, Hock, Hanno R, Steensma, David P, Garcia, Jacqueline S, Luskin, Marlise R, Stone, Richard M, Ballen, Karen K, Rosenblatt, Jacalyn, Avigan, David, Nahas, Myrna R, Mendez, Lourdes M, McAfee, Steven L, Moran, Jenna A, Bergeron, Meghan, Foster, Julia, Bertoli, Christina, Manning, Amity L, McGregor, Kristin L, Fishman, Kaitlyn M, Kuo, Frank C, Baltay, Michele T, Macrae, Molly, Burke, Meghan, Behnan, Tanya, Wey, Margaret C, Som, Tina T, Ramos, Aura Y, Rae, Jessica, Lombardi Story, Jennifer, Nelson, Nicole, Logan, Emma, Connolly, Christine, Neuberg, Donna S, Chen, Yi-Bin, Graubert, Timothy A, Fathi, Amir T

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Aberrant rRNA 2′-O-Methylation Causes Bone Marrow Failure and Defective Immune Function von Nachmani, Daphna, Mendez, Lourdes M., Pandolfi, Pier Paolo

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Circulating Protein Disulfide Isomerase Is Associated with Increased Risk of Thrombosis in JAK2-Mutated Myeloproliferative Neoplasms von Sharda, Anish V., Bogue, Thomas, Barr, Alexandra, Mendez, Lourdes M., Flaumenhaft, Robert, Zwicker, Jeffrey I.

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Circulating Protein Disulfide Isomerase Is Associated with Increased Risk of Thrombosis in JAK2-Mutated Myeloproliferative Neoplasms von Sharda, Anish V., Bogue, Thomas, Barr, Alexandra, Mendez, Lourdes M., Flaumenhaft, Robert, Zwicker, Jeffrey I.

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Abstract 1694: CHIP and AML mutations dictate the composition of hematopoietic microenvironments von Posey, Ryan R., Mendez, Lourdes M., Lee, Jonathan D., Clohessy, John G., Pandolfi, Pier Paolo

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VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex von Sharda, Anish V., Harrison, Joshua, Wilkie, Adrian R., Fang, Chao, Mendez, Lourdes M., Italiano, Joseph E., Flaumenhaft, Robert C.

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Inhibition of ATR with AZD6738 (Ceralasertib) for the Treatment of Progressive or Relapsed Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: Safety and Preliminary Act... von Brunner, Andrew M., Liu, Yiwen, Mendez, Lourdes M., Garcia, Jacqueline S., Amrein, Philip C., Neuberg, Donna S., Dean, Emma, Smith, Simon, Stone, Richard M., Fathi, Amir T., Walter, Matthew J., Graubert, Timothy A., Jacoby, Meagan A.

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A Phase I Study of Asciminib (ABL001) in Combination with Dasatinib and Prednisone for BCR-ABL1-Positive ALL in Adults von Luskin, Marlise R., Stevenson, Kristen E., Mendez, Lourdes M., Wang, Eunice S., Wadleigh, Martha, Garcia, Jacqueline S., Stone, Richard M., An, Hyun Hwan, Hagopian, Ella, Galinsky, Ilene, Rae, Lindsey, Leonard, Rebecca, DeAngelo, Daniel J., Murakami, Mark A.

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Post-Transplant Vaccination with a Personalized Dendritic Cell/AML Fusion Cell Vaccine for Prevention of Relapse von Liegel, Jessica J., Bindal, Poorva, Stone, Richard M., Soiffer, Robert J., Stroopinsky, Dina, Cheloni, Giulia, Bisharat, Lina, Torres, Daniela, Rahimian, Maryam, Yoo, Seo Yeon, Logan, Emma K., Elavalakanar, Pavania, El Banna, Hassan, Hauser, Joshua, Koshy, Anita G., Romee, Rizwan, Ho, Vincent T., Neuberg, Donna S., Liu, Yiwen, Mendez, Lourdes M., Dias, Ajoy L., Ebert, Benjamin L., Kufe, Donald, Avigan, David, Rosenblatt, Jacalyn

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