Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure von Dohle, Wolfgang, Jourdan, Fabrice L, Menchon, Grégory, Prota, Andrea E, Foster, Paul A, Mannion, Pascoe, Hamel, Ernest, Thomas, Mark P, Kasprzyk, Philip G, Ferrandis, Eric, Steinmetz, Michel O, Leese, Mathew P, Potter, Barry V. L

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Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent von Jost, Marco, Chen, Yuwen, Gilbert, Luke A., Horlbeck, Max A., Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y., Stern, Jacob J., Prota, Andrea E., Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O., Tanenbaum, Marvin E., Weissman, Jonathan S.

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Molecular Dynamics as a Tool for Virtual Ligand Screening von Menchon, Grégory, Maveyraud, Laurent, Czaplicki, Georges

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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin von Menchon, Grégory, Prota, Andrea E., Lucena-Agell, Daniel, Bucher, Pascal, Jansen, Rolf, Irschik, Herbert, Müller, Rolf, Paterson, Ian, Díaz, J. Fernando, Altmann, Karl-Heinz, Steinmetz, Michel O.

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Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent von Jost, Marco, Chen, Yuwen, Gilbert, Luke A., Horlbeck, Max A., Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y., Stern, Jacob J., Prota, Andrea E., Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O., Tanenbaum, Marvin E., Weissman, Jonathan S.

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Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents von Brindisi, Margherita, Ulivieri, Cristina, Alfano, Gloria, Gemma, Sandra, de Asís Balaguer, Francisco, Khan, Tuhina, Grillo, Alessandro, Chemi, Giulia, Menchon, Grégory, Prota, Andrea E., Olieric, Natacha, Lucena-Agell, Daniel, Barasoain, Isabel, Diaz, J. Fernando, Nebbioso, Angela, Conte, Mariarosaria, Lopresti, Ludovica, Magnano, Stefania, Amet, Rebecca, Kinsella, Paula, Zisterer, Daniela M., Ibrahim, Ola, O'Sullivan, Jeff, Morbidelli, Lucia, Spaccapelo, Roberta, Baldari, Cosima, Butini, Stefania, Novellino, Ettore, Campiani, Giuseppe, Altucci, Lucia, Steinmetz, Michel O., Brogi, Simone

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Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface von Menchon, Grégory, Bombarde, Oriane, Trivedi, Mansi, Négrel, Aurélie, Inard, Cyril, Giudetti, Brigitte, Baltas, Michel, Milon, Alain, Modesti, Mauro, Czaplicki, Georges, Calsou, Patrick

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Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocryst... von Dohle, Wolfgang, Prota, Andrea E, Menchon, Grégory, Hamel, Ernest, Steinmetz, Michel O, Potter, Barry V. L

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Molecular Dynamics as a Tool for Virtual Ligand Screening von Menchon, Grégory, Maveyraud, Laurent, Czaplicki, Georges

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Anisomycin Injection in Area CA3 of the Hippocampus Impairs Both Short-Term and Long-Term Memories of Contextual Fear von Remaud, Jessica, Ceccom, Johnatan, Carponcy, Julien, Dugué, Laura, Menchon, Gregory, Pech, Stéphane, Halley, Helene, Francés, Bernard, Dahan, Lionel

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Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites von Field, Jessica J, Pera, Benet, Gallego, Juan Estévez, Calvo, Enrique, Rodríguez-Salarichs, Javier, Sáez-Calvo, Gonzalo, Zuwerra, Didier, Jordi, Michel, Andreu, José M, Prota, Andrea E, Ménchon, Grégory, Miller, John H, Altmann, Karl-Heinz, Díaz, J. Fernando

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Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent von Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S

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Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent von Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S

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Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent von Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S

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Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent von Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S

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Criblage virtuel et fonctionnel sur le complexe XRCC4/ADN ligase IV/Cer-XLF de ligature des cassures double-brin de l'ADN : application en radiosensibilisation tumorale von Menchon, Grégory

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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin von Menchon, Grégory, Prota, Andrea E, Lucena-Agell, Daniel, Bucher, Pascal, Jansen, Rolf, Irschik, Herbert, Müller, Rolf, Paterson, Ian, Díaz, J Fernando, Altmann, Karl-Heinz, Steinmetz, Michel O

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Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers von Salvadó, Gemma, Molinuevo, José Luis, Brugulat-Serrat, Anna, Falcon, Carles, Grau-Rivera, Oriol, Suárez-Calvet, Marc, Pavia, Javier, Niñerola-Baizán, Aida, Perissinotti, Andrés, Lomeña, Francisco, Minguillon, Carolina, Fauria, Karine, Zetterberg, Henrik, Blennow, Kaj, Gispert, Juan Domingo

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Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group von Boedhoe, Premika S.W, Abe, Yoshinari, Alonso, Pino, Ameis, Stephanie H, Anticevic, Alan, Arnold, Paul D, Beucke, Jan C, Bollettini, Irene, Bose, Anushree, Brem, Silvia, Calvo, Anna, Calvo, Rosa, Denys, Damiaan, Feusner, Jamie D, Fitzgerald, Kate D, Fouche, Jean-Paul, Fridgeirsson, Egill A, Hibar, Derrek P, Hoexter, Marcelo Q, Hu, Hao, Jahanshad, Neda, James, Anthony, Kathmann, Norbert, Kaufmann, Christian, Lazaro, Luisa, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M, Minuzzi, Luciano, Nakamae, Takashi, Nakao, Tomohiro, Nurmi, Erika, O’Neill, Joseph, Piacentini, John, Piras, Fabrizio, Piras, Federica, Reess, Tim J, Sato, Joao R, Soriano-Mas, Carles, Stevens, Michael C, Szeszko, Philip R, van Wingen, Guido A, Venkatasubramanian, Ganesan, Walitza, Susanne, Wang, Zhen, Yun, Je-Yeon, Stein, Dan J, Boedhoe, Premika S.W, Abe, Yoshinari, Anticevic, Alan, Batistuzzo, Marcelo C, Benedetti, Francesco, Bollettini, Irene, Bose, Anushree, Calvo, Anna, Calvo, Rosa, Cheng, Yuqi, Ciullo, Valentina, Denys, Damiaan, Drechsler, Renate, Fang, Yu, Feusner, Jamie D, Fouche, Jean-Paul, Hanna, Gregory L, Hauser, Tobias U, Huyser, Chaim, Iorio, Mariangela, James, Anthony, Khadka, Sabin, Kwon, Jun Soo, Liu, Yanni, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, McCracken, James T, Miguel, Euripedes C, Morer, Astrid, Narumoto, Jin, Nishida, Seiji, Nurmi, Erika, Pariente, Jose C, Pittenger, Christopher, Piras, Fabrizio, Piras, Federica, Poletti, Sara, Reddy, Y.C. Janardhan, Tang, Jinsong, Vecchio, Daniela, Veltman, Dick J, Venkatasubramanian, Ganesan, Wang, Zhen, Watanabe, Anri, Xu, Jian, Xu, Xiufeng, Yun, Je-Yeon, Zhao, Qing, Thompson, Paul M, van den Heuvel, Odile A

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Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis von Boedhoe, Premika S.W, Schmaal, Lianne, Abe, Yoshinari, Ameis, Stephanie H, Batistuzzo, Marcelo C, Benedetti, Francesco, Beucke, Jan C, Bose, Anushree, Brem, Silvia, Calvo, Anna, Cheng, Yuqi, Cho, Kang Ik K, Dallaspezia, Sara, Gruner, Patricia, Hanna, Gregory L, Hibar, Derrek P, Hoexter, Marcelo Q, Hu, Hao, Huyser, Chaim, Jahanshad, Neda, Kaufmann, Christian, Koch, Kathrin, Lazaro, Luisa, Liu, Yanni, Lochner, Christine, Marsh, Rachel, Mataix-Cols, David, Menchón, José M, Minuzzi, Luciano, Narayanaswamy, Janardhanan C, Piras, Fabrizio, Piras, Federica, Pittenger, Christopher, Reddy, Y.C. Janardhan, Sato, Joao R, Soreni, Noam, Szeszko, Philip R, Xu, Jian, Xu, Xiufeng, Yun, Je-Yeon, Zhao, Qing, Stein, Dan J, Ameis, Stephanie H, Bargalló, Nuria, Batistuzzo, Marcelo C, Benedetti, Francesco, Beucke, Jan C, Boedhoe, Premika S.W, Calvo, Anna, Calvo, Rosa, Cath, Danielle C, Cheng, Yuqi, Cho, Kang Ik K, de Vries, Froukje E, Fang, Yu, Fitzgerald, Kate D, Fouche, Jean-Paul, Giménez, Mònica, Hanna, Gregory L, Hu, Hao, Huyser, Chaim, Ikari, Keisuke, Jahanshad, Neda, Kathmann, Norbert, Kaufmann, Christian, Khadka, Sabin, Koch, Kathrin, Kwon, Jun Soo, Lazaro, Luisa, Liu, Yanni, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M, Minuzzii, Luciano, Morer, Astrid, Nakamae, Takashi, Nakao, Tomohiro, Pittenger, Christopher, Reddy, Y.C. Janardhan, Sato, Joao R, Simpson, H. Blair, Soreni, Noam, Soriano-Mas, Carles, Spalletta, Gianfranco, Stein, Dan J, Stevens, Michael C, Szeszko, Philip R, Thompson, Paul M, Venkatasubramanian, Ganesan, van den Heuvel, Odile A, van der Werf, Ysbrand D, van Wingen, Guido A, Walitza, Susanne, Wang, Zhen, Xu, Jian, Xu, Xiufeng, Yun, Je-Yeon, Zhao, Qing

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