Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes von Hett, Erik C, Xu, Hua, Geoghegan, Kieran F, Gopalsamy, Ariamala, Kyne, Robert E, Menard, Carol A, Narayanan, Arjun, Parikh, Mihir D, Liu, Shenping, Roberts, Lee, Robinson, Ralph P, Tones, Michael A, Jones, Lyn H

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In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels von Cherry, Jonathan J, DiDonato, Christine J, Androphy, Elliot J, Calo, Alessandro, Potter, Kyle, Custer, Sara K, Du, Sarah, Foley, Timothy L, Gopalsamy, Ariamala, Reedich, Emily J, Gordo, Susana M, Gordon, William, Hosea, Natalie, Jones, Lyn H, Krizay, Daniel K, LaRosa, Gregory, Li, Hongxia, Mathur, Sachin, Menard, Carol A, Patel, Paraj, Ramos-Zayas, Rebeca, Rietz, Anne, Rong, Haojing, Zhang, Baohong, Tones, Michael A

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A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS von Xu, Hua, Hett, Erik C, Gopalsamy, Ariamala, Parikh, Mihir D, Geoghegan, Kieran F, Kyne, Jr, Robert E, Menard, Carol A, Narayanan, Arjun, Robinson, Ralph P, Johnson, Douglas S, Tones, Michael A, Jones, Lyn H

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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoi... von Schnute, Mark E, Wennerstål, Mattias, Alley, Jennifer, Bengtsson, Martin, Blinn, James R, Bolten, Charles W, Braden, Timothy, Bonn, Tomas, Carlsson, Bo, Caspers, Nicole, Chen, Ming, Choi, Chulho, Collis, Leon P, Crouse, Kimberly, Färnegårdh, Mathias, Fennell, Kimberly F, Fish, Susan, Flick, Andrew C, Goos-Nilsson, Annika, Gullberg, Hjalmar, Harris, Peter K, Heasley, Steven E, Hegen, Martin, Hromockyj, Alexander E, Hu, Xiao, Husman, Bolette, Janosik, Tomasz, Jones, Peter, Kaila, Neelu, Kallin, Elisabet, Kauppi, Björn, Kiefer, James R, Knafels, John, Koehler, Konrad, Kruger, Lars, Kurumbail, Ravi G, Kyne, Jr, Robert E, Li, Wei, Löfstedt, Joakim, Long, Scott A, Menard, Carol A, Mente, Scot, Messing, Dean, Meyers, Marvin J, Napierata, Lee, Nöteberg, Daniel, Nuhant, Philippe, Pelc, Matthew J, Prinsen, Michael J, Rhönnstad, Patrik, Backström-Rydin, Eva, Sandberg, Johnny, Sandström, Maria, Shah, Falgun, Sjöberg, Maria, Sundell, Aron, Taylor, Alexandria P, Thorarensen, Atli, Trujillo, John I, Trzupek, John D, Unwalla, Ray, Vajdos, Felix F, Weinberg, Robin A, Wood, David C, Xing, Li, Zamaratski, Edouard, Zapf, Christoph W, Zhao, Yajuan, Wilhelmsson, Anna, Berstein, Gabriel

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Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections von Montgomery, Justin I, Brown, Matthew F, Reilly, Usa, Price, Loren M, Abramite, Joseph A, Arcari, Joel, Barham, Rose, Che, Ye, Chen, Jinshan Michael, Chung, Seung Won, Collantes, Elizabeth M, Desbonnet, Charlene, Doroski, Matthew, Doty, Jonathan, Engtrakul, Juntyma J, Harris, Thomas M, Huband, Michael, Knafels, John D, Leach, Karen L, Liu, Shenping, Marfat, Anthony, McAllister, Laura, McElroy, Eric, Menard, Carol A, Mitton-Fry, Mark, Mullins, Lisa, Noe, Mark C, O’Donnell, John, Oliver, Robert, Penzien, Joseph, Plummer, Mark, Shanmugasundaram, Veerabahu, Thoma, Christy, Tomaras, Andrew P, Uccello, Daniel P, Vaz, Alfin, Wishka, Donn G

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Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections von Brown, Matthew F, Reilly, Usa, Abramite, Joseph A, Arcari, Joel T, Oliver, Robert, Barham, Rose A, Che, Ye, Chen, Jinshan Michael, Collantes, Elizabeth M, Chung, Seung Won, Desbonnet, Charlene, Doty, Jonathan, Doroski, Matthew, Engtrakul, Juntyma J, Harris, Thomas M, Huband, Michael, Knafels, John D, Leach, Karen L, Liu, Shenping, Marfat, Anthony, Marra, Andrea, McElroy, Eric, Melnick, Michael, Menard, Carol A, Montgomery, Justin I, Mullins, Lisa, Noe, Mark. C, O’Donnell, John, Penzien, Joseph, Plummer, Mark S, Price, Loren M, Shanmugasundaram, Veerabahu, Thoma, Christy, Uccello, Daniel P, Warmus, Joseph S, Wishka, Donn G

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Heterocyclic methylsulfone hydroxamic acid LpxC inhibitors as Gram-negative antibacterial agents von McAllister, Laura A., Montgomery, Justin I., Abramite, Joseph A., Reilly, Usa, Brown, Matthew F., Chen, Jinshan M., Barham, Rose A., Che, Ye, Chung, Seung Won, Menard, Carol A., Mitton-Fry, Mark, Mullins, Lisa M., Noe, Mark C., O’Donnell, John P., Oliver, Robert M., Penzien, Joseph B., Plummer, Mark, Price, Loren M., Shanmugasundaram, Veerabahu, Tomaras, Andrew P., Uccello, Daniel P.

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Discovery of 3‑Cyano‑N‑(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)‑1H‑pyrrolo[2,3‑b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic A... von Schnute, Mark E, Wennerstål, Mattias, Alley, Jennifer, Bengtsson, Martin, Blinn, James R, Bolten, Charles W, Braden, Timothy, Bonn, Tomas, Carlsson, Bo, Caspers, Nicole, Chen, Ming, Choi, Chulho, Collis, Leon P, Crouse, Kimberly, Färnegårdh, Mathias, Fennell, Kimberly F, Fish, Susan, Flick, Andrew C, Goos-Nilsson, Annika, Gullberg, Hjalmar, Harris, Peter K, Heasley, Steven E, Hegen, Martin, Hromockyj, Alexander E, Hu, Xiao, Husman, Bolette, Janosik, Tomasz, Jones, Peter, Kaila, Neelu, Kallin, Elisabet, Kauppi, Björn, Kiefer, James R, Knafels, John, Koehler, Konrad, Kruger, Lars, Kurumbail, Ravi G, Kyne, Robert E, Li, Wei, Löfstedt, Joakim, Long, Scott A, Menard, Carol A, Mente, Scot, Messing, Dean, Meyers, Marvin J, Napierata, Lee, Nöteberg, Daniel, Nuhant, Philippe, Pelc, Matthew J, Prinsen, Michael J, Rhönnstad, Patrik, Backström-Rydin, Eva, Sandberg, Johnny, Sandström, Maria, Shah, Falgun, Sjöberg, Maria, Sundell, Aron, Taylor, Alexandria P, Thorarensen, Atli, Trujillo, John I, Trzupek, John D, Unwalla, Ray, Vajdos, Felix F, Weinberg, Robin A, Wood, David C, Xing, Li, Zamaratski, Edouard, Zapf, Christoph W, Zhao, Yajuan, Wilhelmsson, Anna, Berstein, Gabriel

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A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpSElectronic supplementary information (ESI) available: Additional experimental... von Xu, Hua, Hett, Erik C, Gopalsamy, Ariamala, Parikh, Mihir D, Geoghegan, Kieran F, Kyne, Robert E, Menard, Carol A, Narayanan, Arjun, Robinson, Ralph P, Johnson, Douglas S, Tones, Michael A, Jones, Lyn H

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Molecular adaptations of the blood–brain barrier promote stress resilience vs. depression von Dudek, Katarzyna A., Dion-Albert, Laurence, Lebel, Manon, LeClairc, Katherine, Labrecque, Simon, Tuck, Ellen, Perez, Carmen Ferrer, Golden, Sam A., Tamminga, Carol, Turecki, Gustavo, Mechawar, Naguib, Russo, Scott J., Menard, Caroline

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VGF function in depression and antidepressant efficacy von Jiang, C, Lin, W-J, Sadahiro, M, Labonté, B, Menard, C, Pfau, M L, Tamminga, C A, Turecki, G, Nestler, E J, Russo, S J, Salton, S R

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Fibrostenotic eosinophilic esophagitis phenotype is defined by a proliferative gene signature von Menard‐Katcher, Calies, Liu, Cuining, Galbraith, Matthew D., Benson, Taylor, Burger, Cassandra, Dobias, Devin, Larsen, Leigha, O'Brien, Carol, Spencer, Lisa A., Furuta, Glenn T., Masterson, Joanne C.

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Social stress induces neurovascular pathology promoting depression von Menard, Caroline, Pfau, Madeline L., Hodes, Georgia E., Kana, Veronika, Wang, Victoria X., Bouchard, Sylvain, Takahashi, Aki, Flanigan, Meghan E., Aleyasin, Hossein, LeClair, Katherine B., Janssen, William G., Labonté, Benoit, Parise, Eric M., Lorsch, Zachary S., Golden, Sam A., Heshmati, Mitra, Tamminga, Carol, Turecki, Gustavo, Campbell, Matthew, Fayad, Zahi A., Tang, Cheuk Ying, Merad, Miriam, Russo, Scott J.

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Histone serotonylation in dorsal raphe nucleus contributes to stress- and antidepressant-mediated gene expression and behavior von Al-Kachak, Amni, Di Salvo, Giuseppina, Fulton, Sasha L., Chan, Jennifer C, Farrelly, Lorna A., Lepack, Ashley E., Bastle, Ryan M., Kong, Lingchun, Cathomas, Flurin, Newman, Emily L., Menard, Caroline, Ramakrishnan, Aarthi, Safovich, Polina, Lyu, Yang, Covington, Herbert E., Shen, Li, Gleason, Kelly, Tamminga, Carol A., Russo, Scott J., Maze, Ian

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Sex-specific transcriptional signatures in human depression von Labonté, Benoit, Engmann, Olivia, Purushothaman, Immanuel, Menard, Caroline, Wang, Junshi, Tan, Chunfeng, Scarpa, Joseph R, Moy, Gregory, Loh, Yong-Hwee E, Cahill, Michael, Lorsch, Zachary S, Hamilton, Peter J, Calipari, Erin S, Hodes, Georgia E, Issler, Orna, Kronman, Hope, Pfau, Madeline, Obradovic, Aleksandar L J, Dong, Yan, Neve, Rachael L, Russo, Scott, Kasarskis, Andrew, Tamminga, Carol, Mechawar, Naguib, Turecki, Gustavo, Zhang, Bin, Shen, Li, Nestler, Eric J

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Unexpectedly high mortality in Pacific herring embryos exposed to the 2007 Cosco Busan oil spill in San Francisco Bay von Incardona, John P, Vines, Carol A, Anulacion, Bernadita F, Baldwin, David H, Day, Heather L, French, Barbara L, Labenia, Jana S, Linbo, Tiffany L, Myers, Mark S, Olson, O. Paul, Sloan, Catherine A, Sol, Sean, Griffin, Frederick J, Menard, Karl, Morgan, Steven G, West, James E, Collier, Tracy K, Ylitalo, Gina M, Cherr, Gary N, Scholz, Nathaniel L

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Fast-moving features in the debris disk around AU Microscopii von Boccaletti, Anthony, Thalmann, Christian, Lagrange, Anne-Marie, Janson, Markus, Augereau, Jean-Charles, Schneider, Glenn, Milli, Julien, Grady, Carol, Debes, John, Langlois, Maud, Mouillet, David, Henning, Thomas, Dominik, Carsten, Maire, Anne-Lise, Beuzit, Jean-Luc, Carson, Joseph, Dohlen, Kjetil, Engler, Natalia, Feldt, Markus, Fusco, Thierry, Ginski, Christian, Girard, Julien H., Hines, Dean, Kasper, Markus, Mawet, Dimitri, Ménard, François, Meyer, Michael R., Moutou, Claire, Olofsson, Johan, Rodigas, Timothy, Sauvage, Jean-Francois, Schlieder, Joshua, Schmid, Hans Martin, Turatto, Massimo, Udry, Stephane, Vakili, Farrokh, Vigan, Arthur, Wahhaj, Zahed, Wisniewski, John

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Dynamical Evidence of a Spiral Arm-driving Planet in the MWC 758 Protoplanetary Disk von Ren, Bin, Dong, Ruobing, van Holstein, Rob G., Ruffio, Jean-Baptiste, Calvin, Benjamin A., Girard, Julien H., Benisty, Myriam, Boccaletti, Anthony, Esposito, Thomas M., Choquet, Élodie, Mawet, Dimitri, Pueyo, Laurent, Stolker, Tomas, Chiang, Eugene, Boer, Jozua de, Debes, John H., Garufi, Antonio, Grady, Carol A., Hines, Dean C., Maire, Anne-Lise, Ménard, François, Millar-Blanchaer, Maxwell A., Perrin, Marshall D., Poteet, Charles A., Schneider, Glenn

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Metabolic dysfunction mediated by HIF-1α contributes to epithelial differentiation defects in eosinophilic esophagitis von Ryan, Sinéad, Crowe, Louise, Almeida Cruz, Sofía N., Galbraith, Matthew D., O’Brien, Carol, Hammer, Juliet A., Bergin, Ronan, Kellett, Shauna K., Markey, Gary E., Benson, Taylor M., Fagan, Olga, Espinosa, Joaquin M., Conlon, Niall, Donohoe, Claire L., McKiernan, Susan, Hogan, Andrew E., McNamee, Eóin N., Furuta, Glenn T., Menard-Katcher, Calies, Masterson, Joanne C.

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Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial von Hill, Kevin D., Kannankeril, Prince J., Jacobs, Jeffrey P., Baldwin, H. Scott, Jacobs, Marshall L., O’Brien, Sean M., Bichel, David P., Graham, Eric M., Blasiole, Brian, Resheidat, Ashraf, Husain, Adil S., Kumar, S. Ram, Kirchner, Jerry L., Gallup, Dianne S., Turek, Joseph W., Bleiweis, Mark, Mettler, Bret, Benscoter, Alexis, Wald, Eric, Karamlou, Tara, Van Bergen, Andrew H., Overman, David, Eghtesady, Pirooz, Butts, Ryan, Kim, John S., Scott, John P., Anderson, Brett R., Swartz, Michael F., McConnell, Patrick I., Vener, David F., Li, Jennifer S.

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