Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets von Sportès, Claude, Hakim, Frances T, Memon, Sarfraz A, Zhang, Hua, Chua, Kevin S, Brown, Margaret R, Fleisher, Thomas A, Krumlauf, Michael C, Babb, Rebecca R, Chow, Catherine K, Fry, Terry J, Engels, Julie, Buffet, Renaud, Morre, Michel, Amato, Robert J, Venzon, David J, Korngold, Robert, Pecora, Andrew, Gress, Ronald E, Mackall, Crystal L

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Age-dependent incidence, time course, and consequences of thymic renewal in adults von Hakim, Frances T, Memon, Sarfraz A, Cepeda, Rosemarie, Jones, Elizabeth C, Chow, Catherine K, Kasten-Sportes, Claude, Odom, Jeanne, Vance, Barbara A, Christensen, Barbara L, Mackall, Crystal L, Gress, Ronald E

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Quantitative analysis of T cell receptor diversity in clinical samples of human peripheral blood von Memon, Sarfraz A., Sportès, Claude, Flomerfelt, Francis A., Gress, Ronald E., Hakim, Frances T.

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Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function von Chu, Yu-Waye, Memon, Sarfraz A., Sharrow, Susan O., Hakim, Frances T., Eckhaus, Michael, Lucas, Philip J., Gress, Ronald E.

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Age-dependent incidence, time course, and consequences of thymic renewal in adults von Hakim, Frances T., Memon, Sarfraz A., Cepeda, Rosemarie, Jones, Elizabeth C., Chow, Catherine K., Kasten-Sportes, Claude, Odom, Jeanne, Vance, Barbara A., Christensen, Barbara L., Mackall, Crystal L., Gress, Ronald E.

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Cutting Edge: Apoptosis Induced by a Chimeric Fas/FLICE Receptor: Lack of Requirement for Fas- or FADD-Binding Proteins von Memon, Sarfraz A, Hou, Jing-zhou, Moreno, M. Belen, Zacharchuk, Charles M

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Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in a T cell hybridoma von Memon, SA, Moreno, MB, Petrak, D, Zacharchuk, CM

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Early Reconstitution of Natural Killer Cells Following Non-Myeloablative Hematopoietic Stem Cell Transplantation Predicts the Development of Acute Graft-Versus-Host Disease von Boyiadzis, Michael, Hakim, Frances T., Memon, Sarfraz A., Dean, Robert, Fowler, Daniel, Gress, Ronald E., Bishop, Michael R.

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Recombinant human IL‐7 (rhIL‐7) preferentially expands CD4+ and CD8+ naïve T cells and enhances T cell receptor (TCR) repertoire diversity von Sportes, Claude, Hakim, Frances T, Memon, Sarfraz A, Zhang, Hua, Brown, Margaret R, Fleisher, Thomas A, Krumlauf, Michael C, Babb, Rebecca R, Chow, Catherine K, Fry, Terry J, Engels, Julie, Buffet, Renaud, Morre, Michel, Venzon, David J, Korngold, Robert, Pecora, Andrew, Mackall, Crystal L, Gress, Ronald E

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IL-15 Plays a Critical Role in CD8+ T-Cell Recovery after Allogeneic Transplantation von Hakim, Frances T., Allen, Kenton, Carson, Jesse M., Boyiadzis, Michael, Memon, Sarfraz A., Dean, Robert, Odom, Jeanne, Wayne, Alan, Fowler, Daniel, Bishop, Michael R., Gress, Ronald E.

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Up-Regulation of NK Cell Activating Receptors Associated with Elevated IL-15 Levels Post-Transplant von Boyiadzis, Michael, Carson, Jesse, Allen, Kenton, Memon, Sarfraz A., Dean, Robert A., Odom, Jeanne, Bishop, Michael R., Gress, Ronald E., Hakim, Frances T.

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Increased Expression of Activating Receptors on NK Cells in the Post-Transplant Period von Boyiadzis, Michael, Carson, Jesse M., Memon, Sarfraz A., Dean, Robert, Castro, Kate, Odom, Jeanne, Bishop, Michael R., Gress, Ronald E., Hakim, Frances T.

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Apoptosis signaling pathways in normal T cells. Differential activity of Bcl-2 and IL-1 beta -converting enzyme family protease inhibitors on glucocorticoid- and Fas-mediated cytot... von Moreno, M B, Memon, SA, Zacharchuk, C M

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Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription von Petrak, D, Memon, SA, Birrer, MJ, Ashwell, JD, Zacharchuk, CM

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A simple assay for examining the effect of transiently expressed genes on programmed cell death von Memon, Sarfraz A., Petrak, Daniel, Belen Moreno, M., Zacharchuk, Charles M.

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We measured TRECs in sorted CD4 and CD8 T cells at the time points shown, and values shown were normalized per 10 cells von Sportès, Claude, T. Hakim, Frances, A. Memon, Sarfraz, Zhang, Hua, S. Chua, Kevin, R. Brown, Margaret, A. Fleisher, Thomas, C. Krumlauf, Michael, R. Babb, Rebecca, K. Chow, Catherine, J. Fry, Terry, Engels, Julie, Buffet, Renaud, Morre, Michel, J. Amato, Robert, J. Venzon, David, Korngold, Robert, Pecora, Andrew, E. Gress, Ronald, L. Mackall, Crystal

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Shown are representative images on PET-CT scan in one subject (42-yr-old female treated with 60 μg/kg/dose) von Sportès, Claude, T. Hakim, Frances, A. Memon, Sarfraz, Zhang, Hua, S. Chua, Kevin, R. Brown, Margaret, A. Fleisher, Thomas, C. Krumlauf, Michael, R. Babb, Rebecca, K. Chow, Catherine, J. Fry, Terry, Engels, Julie, Buffet, Renaud, Morre, Michel, J. Amato, Robert, J. Venzon, David, Korngold, Robert, Pecora, Andrew, E. Gress, Ronald, L. Mackall, Crystal

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Representative data from a single subject treated at 60 μg/kg/d are shown von Sportès, Claude, T. Hakim, Frances, A. Memon, Sarfraz, Zhang, Hua, S. Chua, Kevin, R. Brown, Margaret, A. Fleisher, Thomas, C. Krumlauf, Michael, R. Babb, Rebecca, K. Chow, Catherine, J. Fry, Terry, Engels, Julie, Buffet, Renaud, Morre, Michel, J. Amato, Robert, J. Venzon, David, Korngold, Robert, Pecora, Andrew, E. Gress, Ronald, L. Mackall, Crystal

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Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets-5 von Sportès, Claude, T. Hakim, Frances, A. Memon, Sarfraz, Zhang, Hua, S. Chua, Kevin, R. Brown, Margaret, A. Fleisher, Thomas, C. Krumlauf, Michael, R. Babb, Rebecca, K. Chow, Catherine, J. Fry, Terry, Engels, Julie, Buffet, Renaud, Morre, Michel, J. Amato, Robert, J. Venzon, David, Korngold, Robert, Pecora, Andrew, E. Gress, Ronald, L. Mackall, Crystal

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(A) PBMCs were collected at the time points shown, cryopreserved, and then thawed before analysis von Sportès, Claude, T. Hakim, Frances, A. Memon, Sarfraz, Zhang, Hua, S. Chua, Kevin, R. Brown, Margaret, A. Fleisher, Thomas, C. Krumlauf, Michael, R. Babb, Rebecca, K. Chow, Catherine, J. Fry, Terry, Engels, Julie, Buffet, Renaud, Morre, Michel, J. Amato, Robert, J. Venzon, David, Korngold, Robert, Pecora, Andrew, E. Gress, Ronald, L. Mackall, Crystal

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