Subtype-Selective N-Methyl-d-Aspartate Receptor Antagonists:  Synthesis and Biological Evaluation of 1-(Heteroarylalkynyl)-4-benzylpiperidines von Wright, Jon L, Gregory, Tracy F, Kesten, Suzanne R, Boxer, Peter A, Serpa, Kevin A, Meltzer, Leonard T, Wise, Lawrence D, Espitia, Stephen A, Konkoy, Christopher S, Whittemore, Edward R, Woodward, Richard M

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Evidence for N-methyl- d-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: Possible preferential role for N-methyl- d-aspartate receptors von Christoffersen, C.L., Meltzer, L.T.

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Mouse strains differ under a simple schedule of operant learning von Baron, Scott P, Meltzer, Leonard T

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Reversal of Haloperidol-Induced Extrapyramidal Side Effects in Cebus Monkeys by 8-Hydroxy-2-(di-n-propylamino)tetralin and Its Enantiomers von Christoffersen, B.A, Curt L, Meltzer, Ph.D, Leonard T

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Subtype-Selective N-Methyl-d-aspartate Receptor Antagonists:  Benzimidazalone and Hydantoin as Phenol Replacements von Schelkun, Robert M, Yuen, Po-wai, Serpa, Kevin, Meltzer, Leonard T, Wise, Lawrence D, Whittemore, Edward R, Woodward, Richard M

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Thiazoloindans and Thiazolobenzopyrans:  A Novel Class of Orally Active Central Dopamine (Partial) Agonists von van Vliet, L. Alexander, Rodenhuis, Nienke, Wikström, Håkan, Pugsley, Thomas A, Serpa, Kevin A, Meltzer, Leonard T, Heffner, Thomas G, Wise, Lawrence D, Lajiness, Mary E, Huff, Rita M, Svensson, Kjell, Haenen, Guido R. M. M, Bast, Aalt

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Subtype-Selective N-Methyl-d-aspartate Receptor Antagonists:  Synthesis and Biological Evaluation of 1-(Arylalkynyl)-4-benzylpiperidines von Wright, Jon L, Gregory, Tracy F, Bigge, Christopher F, Boxer, Peter A, Serpa, Kevin, Meltzer, Leonard T, Wise, Lawrence D, Cai, Sui Xiong, Hawkinson, Jon E, Konkoy, Christopher S, Whittemore, Edward R, Woodward, Richard M, Zhou, Zhang-Lin

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Parallel synthesis of a series of subtype-selective NMDA receptor antagonists von GREGORY, T. F, WRIGHT, J. L, WISE, L. D, MELTZER, L. T, SERPA, K. A, KONKOY, C. S, WHITTEMORE, E. R, WOODWARD, R. M

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Aryl 1-But-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as Potential Antipsychotic Agents:  Synthesis and Structure−Activity Relationships von Glase, Shelly A, Akunne, Hyacinth C, Heffner, Thomas G, Jaen, Juan C, MacKenzie, Robert G, Meltzer, Leonard T, Pugsley, Thomas A, Smith, Sarah J, Wise, Lawrence D

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Firing properties of substantia nigra dopaminergic neurons in freely moving rats von Freeman, Arthur S., Meltzer, Leonard T., Bunney, Benjamin S.

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Modulation of dopamine neuronal activity by glutamate receptor subtypes von Meltzer, Leonard T., Christoffersen, Curt L., Serpa, Kevin A.

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The Discovery and Structure-Activity Relationships of 1,2,3,6-Tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine Autoreceptor Agonists and Potential Antipsychotic A... von Wright, Jon L, Caprathe, Bradley W, Downing, Dennis M, Glase, Shelly A, Heffner, Thomas G, Jaen, Juan C, Johnson, Stephen J, Kesten, Suzanne R, MacKenzie, Robert G

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Synthesis and dopamine agonist properties of (+)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol and its enantiomers von DeWald, Horace A, Heffner, Thomas G, Jaen, Juan C, Lustgarten, David M, McPhail, Andrew T, Meltzer, Leonard T, Pugsley, Thomas A, Wise, Lawrence D

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Pharmacokinetics and pharmacodynamics of an investigational antipsychotic agent, CI-1007, in rats and monkeys von FENG, M. R, CORBIN, A. E, WRIGHT, D. S, WANG, Y, CHRISTOFFERSEN, C. L, WILEY, J. N, STRENKOSKI, C. A, TUCKER, E. V, NINTEMAN, F. W, MELTZER, L. T, HEFFNER, T. G

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Identification, characterization and pharmacological profile of three metabolites of (R)-(+)-1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1-yl)methyl]pyridine (CI-1007), a do... von WRIGHT, J. L, DOWNING, D. M, FENG, M. R, HAYES, R. N, HEFFNER, T. G, MACKENZIE, R. G, MELTZER, L. T, PUGSLEY, T. A, WISE, L. D

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4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties von Jaen, Juan C, Wise, Lawrence D, Caprathe, Bradley W, Tecle, Haile, Bergmeier, Stephen, Humblet, Christine C, Heffner, Thomas G, Meltzer, Leonard T, Pugsley, Thomas A

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Lack of involvement of haloperidol-sensitive sigma binding sites in modulation of dopamine neuronal activity and induction of dystonias by antipsychotic drugs von Meltzer, L.T., Christoffersen, C.L., Serpa, K.A., Pugsley, T.A., Razmpour, A., Heffner, T.G.

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PD 158771, a potential antipsychotic agent with D2/D3 partial agonist and 5-HT(1A) agonist actions. II. Preclinical behavioral effects von Corbin, A E, Meltzer, L T, Ninteman, F W, Wiley, J N, Christoffersen, C L, Wustrow, D J, Wise, L D, Pugsley, T A, Heffner, T G

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Discovery of subtype-selective NMDA receptor ligands : 4-benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1A/2B antagonists von WRIGHT, J. L, GREGORY, T. F, WHITTEMORE, E. R, WOODWARD, R. M, YANG, K. C, ZHOU, Z.-L, BOXER, P. A, MELTZER, L. T, SERPA, K. A, WISE, L. D, HONG-BAE, S, HUANG, J. C, KONKOY, C. S, UPASANI, R. B

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Evaluation in rats of the somnogenic, pyrogenic, and central nervous system depressant effects of muramyl dipeptide von MELTZER, L. T, SERPA, K. A, MOOS, W. H

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