The Effect of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition on the Risk of Venous Thromboembolism von Marston, Nicholas A., Gurmu, Yared, Melloni, Giorgio E.M., Bonaca, Marc, Gencer, Baris, Sever, Peter S., Pedersen, Terje R., Keech, Anthony C., Roselli, Carolina, Lubitz, Steven A., Ellinor, Patrick T., O’Donoghue, Michelle L., Giugliano, Robert P., Ruff, Christian T., Sabatine, Marc S.

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Detecting the mutational signature of homologous recombination deficiency in clinical samples von Gulhan, Doga C., Lee, Jake June-Koo, Melloni, Giorgio E. M., Cortés-Ciriano, Isidro, Park, Peter J.

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The origins and genetic interactions of KRAS mutations are allele- and tissue-specific von Cook, Joshua H., Melloni, Giorgio E. M., Gulhan, Doga C., Park, Peter J., Haigis, Kevin M.

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Computational analysis of cancer genome sequencing data von Cortés-Ciriano, Isidro, Gulhan, Doga C., Lee, Jake June-Koo, Melloni, Giorgio E. M., Park, Peter J.

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Estimating and presenting hazard ratios and absolute risks from a Cox model with complex nonlinear interactions von Bellavia, Andrea, Melloni, Giorgio E M, Park, Jeong-Gun, Discacciati, Andrea, Murphy, Sabina A

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Very low-depth whole-genome sequencing in complex trait association studies von Gilly, Arthur, Southam, Lorraine, Suveges, Daniel, Kuchenbaecker, Karoline, Moore, Rachel, Melloni, Giorgio E M, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Ritchie, Graham, Schwartzentruber, Jeremy, Danecek, Petr, Kilian, Britt, Pollard, Martin O, Ge, Xiangyu, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria

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Per-Particle Cardiovascular Risk of Lipoprotein(a) vs Non-Lp(a) Apolipoprotein B-Containing Lipoproteins von Marston, Nicholas A., Melloni, Giorgio E.M., Murphy, Sabina A., Morze, Jakub, Kamanu, Frederick K., Ellinor, Patrick T., Ruff, Christian T., Sabatine, Marc S.

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Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns von Watson, Emma V., Lee, Jake June-Koo, Gulhan, Doga C., Melloni, Giorgio E. M., Venev, Sergey V., Magesh, Rayna Y., Frederick, Abdulrazak, Chiba, Kunitoshi, Wooten, Eric C., Naxerova, Kamila, Dekker, Job, Park, Peter J., Elledge, Stephen J.

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Blood gas analyses in hyperbaric and underwater environments: a systematic review von Paganini, Matteo, Moon, Richard E, Boccalon, Nicole, Melloni, Giorgio E M, Giacon, Tommaso A, Camporesi, Enrico M, Bosco, Gerardo

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Clonal hematopoiesis, cardiovascular events and treatment benefit in 63,700 individuals from five TIMI randomized trials von Marston, Nicholas A., Pirruccello, James P., Melloni, Giorgio E. M., Kamanu, Frederick, Bonaca, Marc P., Giugliano, Robert P., Scirica, Benjamin M., Wiviott, Stephen D., Bhatt, Deepak L., Steg, Philippe Gabriel, Raz, Itamar, Braunwald, Eugene, Libby, Peter, Ellinor, Patrick T., Bick, Alexander G., Sabatine, Marc S., Ruff, Christian T.

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INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments von de Pretis, Stefano, Kress, Theresia, Morelli, Marco J, Melloni, Giorgio E M, Riva, Laura, Amati, Bruno, Pelizzola, Mattia

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Risk of new‐onset diabetes and efficacy of pharmacological weight loss therapy von Moura, Filipe A., Bellavia, Andrea, Berg, David D., Melloni, Giorgio E. M., Feinberg, Mark W., Leiter, Lawrence A., Bohula, Erin A., Morrow, David A., Scirica, Benjamin A., Wiviott, Stephen D., Sabatine, Marc S.

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Organizational aspects of pediatric anesthesia and surgery between two waves of Covid‐19 von Camporesi, Anna, Melloni, Giorgio E. M., Diotto, Veronica, Bertani, Patrizia, La Pergola, Enrico, Pelizzo, Gloria

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1896-LB: Clinical Features and C-Peptide Levels Associated with Diabetic Ketoacidosis in Patients with Type 2 Diabetes on Dapagliflozin vs. Placebo—Insights from DECLARE-TIMI 58 von MI KANG, YU, MELLONI, GIORGIO E.M., CAHN, AVIVIT, RAZ, ITAMAR, MOURA, FILIPE, BHATT, DEEPAK L., INZUCCHI, SILVIO E., LEITER, LAWRENCE A., MCGUIRE, DARREN K., WILDING, JOHN, GAUSE-NILSSON, INGRID A., OSCARSSON, JAN, MARSTON, NICHOLAS, RUFF, CHRISTIAN T., SABATINE, MARC S., WIVIOTT, STEPHEN D.

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1895-LB: Fasting C-Peptide and Type 1 Diabetes Polygenic Score Predict Diabetic Ketoacidosis in People with Type 2 Diabetes in DECLARE-TIMI 58 von MI KANG, YU, MELLONI, GIORGIO E.M., CAHN, AVIVIT, RAZ, ITAMAR, MOURA, FILIPE, BHATT, DEEPAK L., INZUCCHI, SILVIO E., LEITER, LAWRENCE A., MCGUIRE, DARREN K., WILDING, JOHN, GAUSE-NILSSON, INGRID A., OSCARSSON, JAN, MARSTON, NICHOLAS, RUFF, CHRISTIAN T., SABATINE, MARC S., WIVIOTT, STEPHEN D.

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LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer von Melloni, Giorgio E M, de Pretis, Stefano, Riva, Laura, Pelizzola, Mattia, Céol, Arnaud, Costanza, Jole, Müller, Heiko, Zammataro, Luca

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A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data von Melloni, Giorgio E M, Mazzarella, Luca, Bernard, Loris, Bodini, Margherita, Russo, Anna, Luzi, Lucilla, Pelicci, Pier Giuseppe, Riva, Laura

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Mutations targeting the coagulation pathway are enriched in brain metastases von Richichi, Cristina, Fornasari, Lorenzo, Melloni, Giorgio E. M., Brescia, Paola, Patanè, Monica, Del Bene, Massimiliano, Mustafa, Dana A. M., Kros, Johan M., Pollo, Bianca, Pruneri, Giancarlo, Sciandivasci, Angela, Munzone, Elisabetta, DiMeco, Francesco, Pelicci, Pier Giuseppe, Riva, Laura, Pelicci, Giuliana

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The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations von Bodini, Margherita, Ronchini, Chiara, Giacò, Luciano, Russo, Anna, Melloni, Giorgio E.M., Luzi, Lucilla, Sardella, Domenico, Volorio, Sara, Hasan, Syed K., Ottone, Tiziana, Lavorgna, Serena, Lo-Coco, Francesco, Candoni, Anna, Fanin, Renato, Toffoletti, Eleonora, Iacobucci, Ilaria, Martinelli, Giovanni, Cignetti, Alessandro, Tarella, Corrado, Bernard, Loris, Pelicci, Pier Giuseppe, Riva, Laura

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DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes von Melloni, Giorgio Em, Ogier, Alessandro Ge, de Pretis, Stefano, Mazzarella, Luca, Pelizzola, Mattia, Pelicci, Pier Giuseppe, Riva, Laura

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