Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells von Elling, Ulrich, Taubenschmid, Jasmin, Wirnsberger, Gerald, O'Malley, Ronan, Demers, Simon-Pierre, Vanhaelen, Quentin, Shukalyuk, Andrey I., Schmauss, Gerald, Schramek, Daniel, Schnuetgen, Frank, von Melchner, Harald, Ecker, Joseph R., Stanford, William L., Zuber, Johannes, Stark, Alexander, Penninger, Josef M.

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Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal von Rabenhorst, Uta, Thalheimer, Frederic B., Gerlach, Katharina, Kijonka, Marek, Böhm, Stefanie, Krause, Daniela S., Vauti, Franz, Arnold, Hans-Henning, Schroeder, Timm, Schnütgen, Frank, von Melchner, Harald, Rieger, Michael A., Zörnig, Martin

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Mutant non-coding RNA resource in mouse embryonic stem cells von Hansen, Jens, von Melchner, Harald, Wurst, Wolfgang

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Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin von Hahn, Matthias, Dambacher, Silvia, Dulev, Stanimir, Kuznetsova, Anastasia Yurievna, Eck, Simon, Wörz, Stefan, Sadic, Dennis, Schulte, Maike, Mallm, Jan-Philipp, Maiser, Andreas, Debs, Pierre, von Melchner, Harald, Leonhardt, Heinrich, Schermelleh, Lothar, Rohr, Karl, Rippe, Karsten, Storchova, Zuzana, Schotta, Gunnar

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Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5 von Noda, Kazuo, Dabovic, Branka, Takagi, Kyoko, Inoue, Tadashi, Horiguchi, Masahito, Hirai, Maretoshi, Fujikawa, Yusuke, Akama, Tomoya O., Kusumoto, Kenji, Zilberberg, Lior, Sakai, Lynn Y., Koli, Katri, Naitoh, Motoko, von Melchner, Harald, Suzuki, Shigehiko, Rifkin, Daniel B., Nakamura, Tomoyuki

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High Efficiency Gene Correction in Hematopoietic Cells by Donor-Template-Free CRISPR/Cas9 Genome Editing von Sürün, Duran, Schwäble, Joachim, Tomasovic, Ana, Ehling, Roy, Stein, Stefan, Kurrle, Nina, von Melchner, Harald, Schnütgen, Frank

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Transcription Factor PROX1 Induces Colon Cancer Progression by Promoting the Transition from Benign to Highly Dysplastic Phenotype von Petrova, Tatiana V., Nykänen, Antti, Norrmén, Camilla, Ivanov, Konstantin I., Andersson, Leif C., Haglund, Caj, Puolakkainen, Pauli, Wempe, Frank, von Melchner, Harald, Gradwohl, Gérard, Vanharanta, Sakari, Aaltonen, Lauri A., Saharinen, Juha, Gentile, Massimiliano, Clarke, Alan, Taipale, Jussi, Oliver, Guillermo, Alitalo, Kari

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Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells von Cencioni, Chiara, Spallotta, Francesco, Savoia, Matteo, Kuenne, Carsten, Guenther, Stefan, Re, Agnese, Wingert, Susanne, Rehage, Maike, Sürün, Duran, Siragusa, Mauro, Smith, Jacob G., Schnütgen, Frank, von Melchner, Harald, Rieger, Michael A., Martelli, Fabio, Riccio, Antonella, Fleming, Ingrid, Braun, Thomas, Zeiher, Andreas M., Farsetti, Antonella, Gaetano, Carlo

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Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice von Bultmann-Mellin, Insa, Essers, Jeroen, van Heijingen, Paula M, von Melchner, Harald, Sengle, Gerhard, Sterner-Kock, Anja

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Genomewide Production of Multipurpose Alleles for the Functional Analysis of the Mouse Genome von Schnütgen, Frank, De-Zolt, Silke, Van Sloun, Petra, Hollatz, Melanie, Floss, Thomas, Hansen, Jens, Altschmied, Joachim, Seisenberger, Claudia, Ghyselinck, Norbert B., Ruiz, Patricia, Chambon, Pierre, Wurst, Wolfgang, von Melchner, Harald

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A public gene trap resource for mouse functional genomics von Skarnes, William C, von Melchner, Harald, Wurst, Wolfgang, Hicks, Geoff, Nord, Alex S, Cox, Tony, Young, Stephen G, Ruiz, Patricia, Soriano, Phil, Tessier-Lavigne, Marc, Conklin, Bruce R, Stanford, William L, Rossant, Janet

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Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms von Bultmann-Mellin, Insa, Conradi, Anne, Maul, Alexandra C, Dinger, Katharina, Wempe, Frank, Wohl, Alexander P, Imhof, Thomas, Wunderlich, F Thomas, Bunck, Alexander C, Nakamura, Tomoyuki, Koli, Katri, Bloch, Wilhelm, Ghanem, Alexander, Heinz, Andrea, von Melchner, Harald, Sengle, Gerhard, Sterner-Kock, Anja

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Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients von Spallotta Francesco, Cencioni Chiara, Atlante Sandra, Garella Davide, Cocco Mattia, Mori Mattia, Mastrocola Raffaella, Kuenne Carsten, Guenther, Stefan, Nanni Simona, Azzimato Valerio, Zukunft Sven, Kornberger, Angela, Duran, Sürün, Schnütgen Frank, von Melchner Harald, Di Stilo Antonella, Aragno Manuela, Braspenning Maarten, van Criekinge Wim, De Blasio Miles J, Ritchie, Rebecca H, Zaccagnini Germana, Martelli Fabio, Farsetti Antonella, Fleming, Ingrid, Braun, Thomas, Beiras-Fernandez Andres, Botta, Bruno, Collino Massimo, Bertinaria Massimo, Zeiher, Andreas M, Gaetano, Carlo

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Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD von Wempe, Frank, De-Zolt, Silke, Koli, Katri, Bangsow, Thorsten, Parajuli, Nirmal, Dumitrascu, Rio, Sterner-Kock, Anja, Weissmann, Norbert, Keski-Oja, Jorma, von Melchner, Harald

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Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping von Strassman, Alexander, Schnütgen, Frank, Dai, Qi, Jones, Jennifer C, Gomez, Angela C, Pitstick, Lenore, Holton, Nathan E, Moskal, Russell, Leslie, Erin R, von Melchner, Harald, Beier, David R, Bjork, Bryan C

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A Large-Scale, Gene-Driven Mutagenesis Approach for the Functional Analysis of the Mouse Genome von Hansen, Jens, Floss, Thomas, Van Sloun, Petra, Füchtbauer, Ernst-Martin, Vauti, Franz, Arnold, Hans-Hennig, Schnütgen, Frank, Wurst, Wolfgang, von Melchner, Harald, Ruiz, Patricia

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The Epithelial Membrane Protein 1 is a Novel Tight Junction Protein of the Blood—Brain Barrier von Bangsow, Thorsten, Baumann, Ewa, Bangsow, Carmen, Jaeger, Martina H, Pelzer, Bernhard, Gruhn, Petra, Wolf, Sabine, von Melchner, Harald, Stanimirovic, Danica B

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Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD von Heidler, Juliana, Fysikopoulos, Athanasios, Wempe, Frank, Seimetz, Michael, Bangsow, Thorsten, Tomasovic, Ana, Veit, Florian, Scheibe, Susan, Pichl, Alexandra, Weisel, Friederike, Lloyd, K C Kent, Jaksch, Peter, Klepetko, Walter, Weissmann, Norbert, von Melchner, Harald

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Enhanced gene trapping in mouse embryonic stem cells von Schnütgen, Frank, Hansen, Jens, De-Zolt, Silke, Horn, Carsten, Lutz, Marcus, Floss, Thomas, Wurst, Wolfgang, Noppinger, Patricia Ruiz, von Melchner, Harald

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Gene trapping identifies a putative tumor suppressor and a new inducer of cell migration von Guardiola-Serrano, Francisca, Haendeler, Judith, Lukosz, Margarete, Sturm, Karsten, Melchner, Harald von, Altschmied, Joachim

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