The immunological consequences of radiation‐induced DNA damage von Wilkins, Anna C, Patin, Emmanuel C, Harrington, Kevin J, Melcher, Alan A

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Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma von McKelvey, Kelly J, Wilson, Erica B, Short, Susan, Melcher, Alan A, Biggs, Michael, Diakos, Connie I, Howell, Viive M

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Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity von Wilson, Erica B, El-Jawhari, Jehan J, Neilson, Abbie L, Hall, Geoffrey D, Melcher, Alan A, Meade, Josephine L, Cook, Graham P

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Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy von Chan Wah Hak, Charleen M L, Rullan, Antonio, Patin, Emmanuel C, Pedersen, Malin, Melcher, Alan A, Harrington, Kevin J

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Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy von Patin, Emmanuel C., Nenclares, Pablo, Chan Wah Hak, Charleen, Dillon, Magnus T., Patrikeev, Anton, McLaughlin, Martin, Grove, Lorna, Foo, Shane, Soliman, Heba, Barata, Joao P., Marsden, Joanna, Baldock, Holly, Gkantalis, Jim, Roulstone, Victoria, Kyula, Joan, Burley, Amy, Hubbard, Lisa, Pedersen, Malin, Smith, Simon A., Clancy-Thompson, Eleanor, Melcher, Alan A., Ono, Masahiro, Rullan, Antonio, Harrington, Kevin J.

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The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study von Punta, Marco, Jennings, Victoria A, Melcher, Alan A, Lise, Stefano

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The Case of Oncolytic Viruses Versus the Immune System: Waiting on the Judgment of Solomon von PRESTWICH, Robin J, ERRINGTON, Fiona, DIAZ, Rosa M, PANDHA, Hardev S, HARRINGTON, Kevin J, MELCHER, Alan A, VILE, Richard G

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Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade von Patin, Emmanuel C, Dillon, Magnus T, Nenclares, Pablo, Grove, Lorna, Soliman, Heba, Leslie, Isla, Northcote, Davina, Bozhanova, Galabina, Crespo-Rodriguez, Eva, Baldock, Holly, Whittock, Harriet, Baker, Gabriella, Kyula, Joan, Guevara, Jeane, Melcher, Alan A, Harper, James, Ghadially, Hormas, Smith, Simon, Pedersen, Malin, McLaughlin, Martin, Harrington, Kevin J

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RIPK1‐mediated immunogenic cell death promotes anti‐tumour immunity against soft‐tissue sarcoma von Smith, Henry G, Jamal, Kunzah, Dayal, Jasbani HS, Tenev, Tencho, Kyula‐Currie, Joan, Guppy, Naomi, Gazinska, Patrycja, Roulstone, Victoria, Liccardi, Gianmaria, Davies, Emma, Roxanis, Ioannis, Melcher, Alan A, Hayes, Andrew J, Inman, Gareth J, Harrington, Kevin J, Meier, Pascal

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Inflammatory microenvironment remodelling by tumour cells after radiotherapy von McLaughlin, Martin, Patin, Emmanuel C., Pedersen, Malin, Wilkins, Anna, Dillon, Magnus T., Melcher, Alan A., Harrington, Kevin J.

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Progress in clinical oncolytic virus-based therapy for hepatocellular carcinoma von Jebar, Adel H, Errington-Mais, Fiona, Vile, Richard G, Selby, Peter J, Melcher, Alan A, Griffin, Stephen

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Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication von Prestwich, Robin J, Ilett, Elizabeth J, Errington, Fiona, Diaz, Rosa M, Steele, Lynette P, Kottke, Tim, Thompson, Jill, Galivo, Feorillo, Harrington, Kevin J, Pandha, Hardev S, Selby, Peter J, Vile, Richard G, Melcher, Alan A

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Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity von PRESTWICH, Robin J, ERRINGTON, Fiona, SELBY, Peter J, VILE, Richard G, MELCHER, Alan A, ILETT, Elizabeth J, MORGAN, Ruth S. M, SCOTT, Karen J, KOTTKE, Timothy, THOMPSON, Jill, MORRISON, Ewan E, HARRINGTON, Kevin J, PANDHA, Hardev S

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Cytotoxic and immune‐mediated killing of human colorectal cancer by reovirus‐loaded blood and liver mononuclear cells von Adair, Robert A., Scott, Karen J., Fraser, Sheila, Errington‐Mais, Fiona, Pandha, Hardev, Coffey, Matt, Selby, Peter, Cook, Graham P., Vile, Richard, Harrington, Kevin J., Toogood, Giles, Melcher, Alan A.

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Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization von LLETT, Elizabeth J, BARCENA, Montserrat, HOEBEN, Rob C, VILE, Richard G, MELCHER, Alan A, ERRINGTON-MAIS, Fiona, GRIFFIN, Stephen, HARRINGTON, Kevin J, PANDHA, Hardev S, COFFEY, Matthew, SELBY, Peter J, LIMPENS, Ronald W. A. L, MOMMAAS, Mieke

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The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism von McLaughlin, Martin, Pedersen, Malin, Roulstone, Victoria, Bergerhoff, Katharina F., Smith, Henry G., Whittock, Harriet, Kyula, Joan N., Dillon, Magnus T., Pandha, Hardev S., Vile, Richard, Melcher, Alan A., Harrington, Kevin J.

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Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway von Twigger, Katie, Roulstone, Victoria, Kyula, Joan, Karapanagiotou, Eleni M, Syrigos, Konstantinos N, Morgan, Richard, White, Christine, Bhide, Shreerang, Nuovo, Gerard, Coffey, Matt, Thompson, Brad, Jebar, Adel, Errington, Fiona, Melcher, Alan A, Vile, Richard G, Pandha, Hardev S, Harrington, Kevin J

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Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21 von Müller, Louise M E, Holmes, Matthew, Michael, Joanne L, Scott, Gina B, West, Emma J, Scott, Karen J, Parrish, Christopher, Hall, Kathryn, Stäble, Sina, Jennings, Victoria A, Cullen, Matthew, McConnell, Stewart, Langton, Catherine, Tidswell, Emma L, Shafren, Darren, Samson, Adel, Harrington, Kevin J, Pandha, Hardev, Ralph, Christy, Kelly, Richard J, Cook, Gordon, Melcher, Alan A, Errington-Mais, Fiona

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Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer von Crespo-Rodriguez, Eva, Bergerhoff, Katharina, Bozhanova, Galabina, Foo, Shane, Patin, Emmanuel C, Whittock, Harriet, Buus, Richard, Haider, Syed, Muirhead, Gareth, Thway, Khin, Newbold, Kate, Coffin, Robert S, Vile, Richard G, Kim, Dae, McLaughlin, Martin, Melcher, Alan A, Harrington, Kevin J, Pedersen, Malin

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Enhanced In vitro and In vivo Cytotoxicity of Combined Reovirus and Radiotherapy von TWIGGER, Katie, VIDAL, Laura, ERRINGTON, Fiona, MELCHER, Alan A, HARRINGTON, Kevin J, WHITE, Christine L, DE BONO, Johann S, BHIDE, Shreerang, COFFEY, Matt, THOMPSON, Brad, VILE, Richard G, HEINEMANN, Lucy, PANDHA, Hardev S

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