Discovery of the Selective Androgen Receptor Modulator MK-0773 Using a Rational Development Strategy Based on Differential Transcriptional Requirements for Androgenic Anabolism Ver... von Schmidt, Azriel, Kimmel, Donald B., Bai, Chang, Scafonas, Angela, Rutledge, SuJane, Vogel, Robert L., McElwee-Witmer, Sheila, Chen, Fang, Nantermet, Pascale V., Kasparcova, Viera, Leu, Chih-tai, Zhang, Hai-Zhuan, Duggan, Mark E., Gentile, Michael A., Hodor, Paul, Pennypacker, Brenda, Masarachia, Patricia, Opas, Evan E., Adamski, Sharon A., Cusick, Tara E., Wang, Jiabing, Mitchell, Helen J., Kim, Yuntae, Prueksaritanont, Thomayant, Perkins, James J., Meissner, Robert S., Hartman, George D., Freedman, Leonard P., Harada, Shun-ichi, Ray, William J.

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Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands von Schmidt, Azriel, Harada, Shun-Ichi, Kimmel, Donald B., Bai, Chang, Chen, Fang, Rutledge, Su Jane, Vogel, Robert L., Scafonas, Angela, Gentile, Michael A., Nantermet, Pascale V., McElwee-Witmer, Sheila, Pennypacker, Brenda, Masarachia, Patricia, Sahoo, Soumya P., Kim, Yuntae, Meissner, Robert S., Hartman, George D., Duggan, Mark E., Rodan, Gideon A., Towler, Dwight A., Ray, William J.

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Autoencapsulation Through Intermolecular Forces: A Synthetic Self-Assembling Spherical Complex von Meissner, Robert S., Rebek, Julius, de Mendoza, Javier

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Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator von Rudd, Michael T., Manley, Peter J., Hanney, Barbara, Meng, Zhaoyang, Shu, Youheng, de Leon, Pablo, Frie, Jessica L., Han, Yongxin, Wai, Jenny Miu-Chun, Yang, Zhi-Qiang, Perkins, James J., Hurzy, Danielle M., Manikowski, Jesse J., Zhu, Hong, Bungard, Christopher J., Converso, Antonella, Meissner, Robert S., Cosden, Mali L., Hayashi, Ikuo, Ma, Lei, O’Brien, Julie, Uebele, Victor N., Schachter, Joel B., Bhandari, Neetesh, Ward, Gwendolyn J., Fillgrove, Kerry L., Lu, Bing, Liang, Yuexia, Dubost, David C., Puri, Vanita, Eddins, Donnie M., Vardigan, Joshua D., Drolet, Robert E., Kern, Jonathan T., Uslaner, Jason M.

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Discovery of [ 11 C]MK-8056: A Selective PET Imaging Agent for the Study of mGluR 2 Negative Allosteric Modulators von Perkins, James J, McQuade, Paul, Bungard, Christopher J, Diamond, Tracy L, Gantert, Liza T, Gotter, Anthony L, Hanney, Barbara, Hills, Ivory D, Hurzy, Danielle M, Joshi, Aniket, Kern, Jonathan T, Schlegel, Kelly-Ann S, Manikowski, Jesse J, Meng, Zhaoyang, O'Brien, Julie A, Roecker, Anthony J, Smith, Sean M, Uslaner, Jason M, Hostetler, Eric, Meissner, Robert S

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Identification of an anabolic selective androgen receptor modulator that actively induces death of androgen-independent prostate cancer cells von Schmidt, Azriel, Meissner, Robert S, Gentile, Michael A, Chisamore, Michael J, Opas, Evan E, Scafonas, Angela, Cusick, Tara E, Gambone, Carlo, Pennypacker, Brenda, Hodor, Paul, Perkins, James J, Bai, Chang, Ferraro, Damien, Bettoun, David J, Wilkinson, Hilary A, Alves, Stephen E, Flores, Osvaldo, Ray, William J

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The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator von Brandish, Philip E., Anderson, Kenneth, Baltus, Gretchen A., Bai, Chang, Bungard, Christopher J., Bunting, Patricia, Byford, Alan, Chiu, Chi-Sung, Cicmil, Milenko, Corcoran, Halea, Euler, Danielle, Fisher, John E., Gambone, Carlo, Hasbun-Manning, Martha, Kuklin, Nelly, Landis, Elizabeth, Lifsted, Traci Q., McElwee-Witmer, Sheila, McIntosh, Ian S., Meissner, Robert S., Miao, John, Mitchell, Helen J., Musselman, Amy, Schmidt, Azriel, Shin, John, Szczerba, Peter, Thompson, Charles D., Tribouley, Catherine, Vogel, Robert L., Warrier, Sudha, Hershey, James C.

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Discovery of selective glucocorticoid receptor modulator MK-5932 von Bungard, Christopher J., Hartman, George D., Manikowski, Jesse J., Perkins, James J., Bai, Chang, Brandish, Philip E., Euler, Danielle H., Hershey, James C., Schmidt, Azriel, Fang, Yulin, Norcross, Ryan T., Rushmore, Tom H., Thompson, Charles D., Meissner, Robert S.

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Design, Synthesis, and Biological Evaluation of 16-Substituted 4-Azasteroids as Tissue-Selective Androgen Receptor Modulators (SARMs) von Mitchell, Helen J, Dankulich, William P, Hartman, George D, Prueksaritanont, Thomayant, Schmidt, Azriel, Vogel, Robert L, Bai, Chang, McElwee-Witmer, Sheila, Zhang, Hai Z, Chen, Fang, Leu, Chih-Tai, Kimmel, Donald B, Ray, William J, Nantermet, Pascale, Gentile, Michael A, Duggan, Mark E, Meissner, Robert S

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Nonpeptide αvβ3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent αvβ3 Antagonist for the Prevention and Treatment of Osteoporosis von Hutchinson, John H, Halczenko, Wasyl, Brashear, Karen M, Breslin, Michael J, Coleman, Paul J, Duong, Le T, Fernandez-Metzler, Carmen, Gentile, Michael A, Fisher, John E, Hartman, George D, Huff, Joel R, Kimmel, Donald B, Leu, Chih-Tai, Meissner, Robert S, Merkle, Kara, Nagy, Rose, Pennypacker, Brenda, Perkins, James J, Prueksaritanont, Thomayant, Rodan, Gideon A, Varga, Sandor L, Wesolowski, Greg A, Zartman, Amy E, Rodan, Sevgi B, Duggan, Mark E

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Convergent synthesis of polyether ionophore antibiotics: protective manipulation and synthesis of monensin A von Ireland, Robert E, Meissner, Robert S, Rizzacasa, Mark A

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Convergent synthesis of polyether ionophore antibiotics: synthesis of the spiroketal and tricyclic glycal segments of monensin von Ireland, Robert E, Armstrong, Joseph D, Lebreton, Jacques, Meissner, Robert S, Rizzacasa, Mark A

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Nonpeptide αvβ3 antagonists. Part 2: Constrained glycyl amides derived from the RGD tripeptide von MEISSNER, Robert S, PERKINS, James J, RODAN, Gideon A, RODAN, Sevgi B, WHITMAN, David B, WESOLOWSKI, Gregg A, DUGGAN, Mark E, DUONG, Le T, HARTMAN, George D, HOFFMAN, William F, HUFF, Joel R, IHLE, Nathan C, LEU, Chih-Tai, NAGY, Rose M, NAYLOR-OLSEN, Adel

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Convenient method for the titration of amide base solutions von Ireland, Robert E, Meissner, Robert S

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Nonpeptide αvβ3 antagonists : identification of potent, chain-shortened 7-oxo RGD mimetics von ZARTMAN, Amy E, DUONG, Le T, FEMANDEZ-METZLER, Carmen, HARTMAN, George D, LEU, Chih-Tai, PRUEKSARITANONT, Thomayant, RODAN, Gideon A, RODAN, Sevgi B, DUGGAN, Mark E, MEISSNER, Robert S

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Non-peptide αvβ3 antagonists: Identification of potent, chain-shortened RGD mimetics that incorporate a central pyrrolidinone constraint von PERKINS, James J, DUONG, Le T, DUGGAN, Mark E, MEISSNER, Robert S, FERNANDEZ-METZLER, Carmen, HARTMAN, George D, KIMMEL, Donald B, LEU, Chih-Tai, LYNCH, Joseph J, PRUEKSARITANONT, Thomayant, RODAN, Gideon A, RODAN, Sevgi B

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Discovery of [11C]MK-8056: A Selective PET Imaging Agent for the Study of mGluR2 Negative Allosteric Modulators von Perkins, James J., McQuade, Paul, Bungard, Christopher J., Diamond, Tracy L., Gantert, Liza T., Gotter, Anthony L., Hanney, Barbara, Hills, Ivory D., Hurzy, Danielle M., Joshi, Aniket, Kern, Jonathan T., Schlegel, Kelly-Ann S., Manikowski, Jesse J., Meng, Zhaoyang, O’Brien, Julie A., Roecker, Anthony J., Smith, Sean M., Uslaner, Jason M., Hostetler, Eric, Meissner, Robert S.

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Discovery of 11CMK-8056: A Selective PET Imaging Agent for the Study of mGluR2 Negative Allosteric Modulators von Perkins, James J, McQuade, Paul, Bungard, Christopher J, Diamond, Tracy L, Gantert, Liza T, Gotter, Anthony L, Hanney, Barbara, Hills, Ivory D, Hurzy, Danielle M, Joshi, Aniket, Kern, Jonathan T, Schlegel, Kelly-Ann S, Manikowski, Jesse J, Meng, Zhaoyang, O'Brien, Julie A, Roecker, Anthony J, Smith, Sean M, Uslaner, Jason M, Hostetler, Eric, Meissner, Robert S

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Synthesis of 2-(alkylamino)benzimidazoles von Perkins, James J., Zartman, Amy E., Meissner, Robert S.

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Nonpeptide alpha(v)beta(3) antagonists. Part 2: constrained glycyl amides derived from the RGD tripeptide von Meissner, Robert S, Perkins, James J, Duong, Le T, Hartman, George D, Hoffman, William F, Huff, Joel R, Ihle, Nathan C, Leu, Chih Tai, Nagy, Rose M, Naylor-Olsen, Adel, Rodan, Gideon A, Rodan, Sevgi B, Whitman, David B, Wesolowski, Gregg A, Duggan, Mark E

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