Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults von Rakshit, Srabanti, Adiga, Vasista, Ahmed, Asma, Parthiban, Chaitra, Chetan Kumar, Nirutha, Dwarkanath, Pratibha, Shivalingaiah, Sudarshan, Rao, Srishti, D'Souza, George, Dias, Mary, Maguire, Thomas J A, Doores, Katie J, Zoodsma, Martijn, Geckin, Busranur, Dasgupta, Prokar, Babji, Sudhir, van Meijgaarden, Krista E, Joosten, Simone A, Ottenhoff, Tom H M, Li, Yang, Netea, Mihai G, Stuart, Kenneth D, De Rosa, Stephen C, McElrath, M Juliana, Vyakarnam, Annapurna

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BCG revaccination in adults enhances pro-inflammatory markers of trained immunity along with anti-inflammatory pathways von Ahmed, Asma, Tripathi, Himanshu, van Meijgaarden, Krista E., Kumar, Nirutha Chetan, Adiga, Vasista, Rakshit, Srabanti, Parthiban, Chaitra, Eveline J, Sharon, D’Souza, George, Dias, Mary, Ottenhoff, Tom H.M., Netea, Mihai G., Joosten, Simone A., Vyakarnam, Annapurna

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Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment von Joosten, Simone A, van Meijgaarden, Krista E, Del Nonno, Franca, Baiocchini, Andrea, Petrone, Linda, Vanini, Valentina, Smits, Hermelijn H, Palmieri, Fabrizio, Goletti, Delia, Ottenhoff, Tom H M

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Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represen... von van Meijgaarden, Krista E, Haks, Mariëlle C, Caccamo, Nadia, Dieli, Francesco, Ottenhoff, Tom H M, Joosten, Simone A

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A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity von Li, Wenchao, Moorlag, Simone J.C.F.M., Koeken, Valerie A.C.M., Röring, Rutger J., de Bree, L. Charlotte J., Mourits, Vera P., Gupta, Manoj K., Zhang, Bowen, Fu, Jianbo, Zhang, Zhenhua, Grondman, Inge, van Meijgaarden, Krista E., Zhou, Liang, Alaswad, Ahmed, Joosten, Leo A.B., van Crevel, Reinout, Xu, Cheng-Jian, Netea, Mihai G., Li, Yang

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Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19 von Pongracz, Tamas, Nouta, Jan, Wang, Wenjun, van Meijgaarden, Krista E., Linty, Federica, Vidarsson, Gestur, Joosten, Simone A., Ottenhoff, Tom H.M., Hokke, Cornelis H., de Vries, Jutte J.C., Arbous, Sesmu M., Roukens, Anna H.E., Wuhrer, Manfred

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BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination von van Meijgaarden, Krista E., Li, Wenchao, Moorlag, Simone J. C. F. M., Koeken, Valerie A. C. M., Koenen, Hans J. P. M., Joosten, Leo A. B., Vyakarnam, Annapurna, Ahmed, Asma, Rakshit, Srabanti, Adiga, Vasista, Ottenhoff, Tom H. M., Li, Yang, Netea, Mihai G., Joosten, Simone A.

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Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines von Smith, Steven G, Smits, Kaatje, Joosten, Simone A, van Meijgaarden, Krista E, Satti, Iman, Fletcher, Helen A, Caccamo, Nadia, Dieli, Francesco, Mascart, Francoise, McShane, Helen, Dockrell, Hazel M, Ottenhoff, Tom H M

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C-Terminal PEGylation Improves SAAP-148 Peptide’s Immunomodulatory Activities von van Gent, Miriam E., Schonkeren-Ravensbergen, Bep, Achkif, Asma, Beentjes, Daan, Dolezal, Natasja, van Meijgaarden, Krista E., Drijfhout, Jan Wouter, Nibbering, Peter H.

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Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q von Niewold, Paula, Dijkstra, Douwe J., Cai, Yi, Goletti, Delia, Palmieri, Fabrizio, van Meijgaarden, Krista E., Verreck, Frank A. W., Akkerman, Onno W., Hofland, Regina W., Delemarre, Eveline M., Nierkens, Stefan, Verheul, Marije K., Pollard, Andrew J., van Dissel, Jaap T., Ottenhoff, Tom H. M., Trouw, Leendert A., Joosten, Simone A.

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Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity von Joosten, Simone A, van Meijgaarden, Krista E, van Weeren, Pascale C, Kazi, Fatima, Geluk, Annemieke, Savage, Nigel D L, Drijfhout, Jan W, Flower, Darren R, Hanekom, Willem A, Klein, Michèl R, Ottenhoff, Tom H M

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CD8+ regulatory T cells, and not CD4+ T cells, dominate suppressive phenotype and function after in vitro live Mycobacterium bovis-BCG activation of human cells von Boer, Mardi C, van Meijgaarden, Krista E, Joosten, Simone A, Ottenhoff, Tom H M

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Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies von van Meijgaarden, Krista E, Khatri, Bhagwati, Smith, Steven G, Drittij, Anne M F H, de Paus, Roelof A, Goeman, Jelle J, Ho, Mei M, Dockrell, Hazel M, McShane, Helen, Joosten, Simone A, Ottenhoff, Tom H M

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Cell-Mediated Immune Responses to in vivo-Expressed and Stage-Specific Mycobacterium tuberculosis Antigens in Latent and Active Tuberculosis Across Different Age Groups von Coppola, Mariateresa, Villar-Hernandez, Raquel, Van Meijgaarden, Krista E., Latorre, Irene, Muriel Moreno, Beatriz, Garcia-Garcia, Esther, Franken, Kees L. M. C., Prat, Cristina, Stojanovic, Zoran, De Souza Galvao, Maria Luiza, Millet, Joan-Pau, Sabria, Josefina, Sanchez-Montalva, Adrian, Noguera-Julian, Antoni, Geluk, Annemieke, Dominguez, Jose, Ottenhoff, Tom H. M.

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T-cell regulation in lepromatous leprosy von Bobosha, Kidist, Wilson, Louis, van Meijgaarden, Krista E, Bekele, Yonas, Zewdie, Martha, van der Ploeg-van Schip, Jolien J, Abebe, Markos, Hussein, Jemal, Khadge, Saraswoti, Neupane, Kapil D, Hagge, Deanna A, Jordanova, Ekaterina S, Aseffa, Abraham, Ottenhoff, Tom H M, Geluk, Annemieke

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Disparate Tuberculosis Disease Development in Macaque Species Is Associated With Innate Immunity von Dijkman, Karin, Vervenne, Richard A W, Sombroek, Claudia C, Boot, Charelle, Hofman, Sam O, van Meijgaarden, Krista E, Ottenhoff, Tom H M, Kocken, Clemens H M, Haanstra, Krista G, Vierboom, Michel P M, Verreck, Frank A W

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Identification of a human CD8⁺ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4 von Joosten, Simone A, van Meijgaarden, Krista E, Savage, Nigel D.L, de Boer, Tjitske, Triebel, Frédéric, van der Wal, Annemieke, de Heer, Emile, Klein, Michèl R, Geluk, Annemieke, Ottenhoff, Tom H.M

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Innovative Strategies to Identify M. tuberculosis Antigens and Epitopes Using Genome-Wide Analyses von Geluk, Annemieke, van Meijgaarden, Krista E, Joosten, Simone A, Commandeur, Susanna, Ottenhoff, Tom H M

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Mtb -Specific HLA-E-Restricted T Cells Are Induced during Mtb Infection but Not after BCG Administration in Non-Human Primates and Humans von Voogd, Linda, van Wolfswinkel, Marjolein, Satti, Iman, White, Andrew D, Dijkman, Karin, Gela, Anele, van Meijgaarden, Krista E, Franken, Kees L M C, Marshall, Julia L, Ottenhoff, Tom H M, Scriba, Thomas J, McShane, Helen, Sharpe, Sally A, Verreck, Frank A W, Joosten, Simone A

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Analysis of Immune Responses against a Wide Range of Mycobacterium tuberculosis Antigens in Patients with Active Pulmonary Tuberculosis von Kassa, Desta, Ran, Leonie, Geberemeskel, Wudneh, Tebeje, Mekashaw, Alemu, Amelewerk, Selase, Alemayehu, Tegbaru, Belete, Franken, Kees L M C, Friggen, Annemieke H, van Meijgaarden, Krista E, Ottenhoff, Tom H M, Wolday, Dawit, Messele, Tsehaynesh, van Baarle, Debbie

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